See LKT's Specialty Chemicals
See LKT's Product Line
 
Alphabetized - A
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
A0099 A-779    

A potent and selective antagonist for the heptapeptide angiotensin-(1-7)[ANG-(1-7)]. It prevents ANG-(1-7)-induced inhibition of angiogenesis.

Santos, R.A; Campagnole-Santos, M.J.; Baracho, N.C., et.al. Brain Res. Bull 35:293-298 (1994). Machado, R.D.; Santos, R.A., Andrade, S.P. Amer. J Physio-Reg. Integ. & Comp. Physio 280:R994-RR1000 (2001).

1 mg
2 mg
5 mg
$57.60
$97.60
$172.80
  A23187, Free acid
See Calcimycin C0246
   
A0101 A23187, 4-Bromo    
 

4-Bromo-A-23187, 4-BrA23187, 4-Bra23187
C29H36BrN3O6       Mol.Wt.: 602.52       [76455-82-8]
A halogenated analogue of A23187. It is a nonfluorescent Ca2+ ionophore used in calibration for determining cytoplasmic Ca2+ by fluorescent probes.

Deber CM., Tom-Kun J., Mack E., Grinstein S. Anal Biochem 146: 349-352 (1985).

1 mg
5 mg
$72.00
$294.00
A0102 A23187, Ca-Mg    
  (C29H36N3O6)22Mg,    (C29H36N3O2)2Ca   Mol.Wt.: 523.62
A calcium, magnesium salt of A23187, a calcium ionophore used to increase intracellular calcium levels in cells.

Mickelson et.al. Arch Biochem Biosphys. 242: 127-136 (1985).
Andersson D, Zygmunt P, Movahed P, Anderson T, Hogestatt E. Br J Pharmacol. 129: 1490-6 (2000).

5 mg
10 mg
$54.00
$100.00
A0025 17-AAG    
 

17-(Allylamino)-17-desmethoxy-geldanamycin; allylaminogeldanamycin
An anologue of geldanamycin. It is a Hsp90 antagonist that induces apoptosis in human leukemia cells. It has been shown to enhance paclitaxel-mediated cytotoxicity and downregulate vascular endothelial factor expression.

Rahmani M, Yu C, Dai Y et al. Cancer Research. 63:8420-7 (2003).
Nguyen DM, Lorang D, Chen GA et al. Annals of Thoracic Surgery. 72:371-8 (2001).

0.5 mg
1 mg
$202.30
$274.40
A0501 Abamectin    
 

An insecticide and antihelmintic agent made up of a mixture of avermectins.

Lasota JA, Dybas RA. Acta Leidensia. 59:217-225 (1990)
Ali A, Nayar JK. J Am Mosquito Control Assoc. 1:384-386 (1985).

1 g
5 g
25 g
$28.00
$95.20
$364.00
A0802 Acarbose    
 

An α-glucosidase inhibitor that inhibits sucrose digestion in rats.
It has been found to reduce the risk of cardiovascular disease and hypertension.

Krause HP, Keup U, Puls, W. Digestion. 23:486-94 (1982).
Chiasson JL, Josse RG, Gomis R et al. JAMA. 23:486-94 (2003).

1 g
5 g
25 g
$39.50
$154.00
$616.00
A0812 Ac-D-E    
    5 mg
10 mg
25 mg
$32.00
$96.00
$39.50
A1017 Aceclofenac    
 

A non-steroidal anti-inflammatory drug. It possesses potent inhibitory activity in several models of acute and chronic inflammation. It has a more favorable therapeutic ratio compared to indomethacin, diclofenac, naproxen, and phenylbutazone.

Yamazaki R, Kawai S, Matsuzaki T et al. Eur J Pharmacol. 329:181-7 (1997).
Grau M, Guasch J, Montero JL et al. Arzneimittelforschung. 41:1265-76 (1991).

5 g
25 g
100 g
$39.50
$154.00
$462.00
A0816 Acemetacin    
 

A non-steroidal anti-inflammatory drug. It possesses potent inhibitory activity in several models of acute and chronic inflammation. It has a more favorable therapeutic ratio compared to indomethacin, diclofenac, naproxen, and phenylbutazone.

Yamazaki R, Kawai S, Matsuzaki T et al. Eur J Pharmacol. 329:181-7 (1997).
Grau M, Guasch J, Montero JL et al. Arzneimittelforschung. 41:1265-76 (1991).

5 g
25 g
100 g
$39.50
$154.00
$462.00
A0817 D,L-1'-Acetoxychavicol acetate    
RT

A xanthine oxidase inhibitor shown to possess chemopreventive
potential against both oral and colonic tumorigenesis in rats.


Ohnishi M, Tanaka T, Makita H et al. Jpn J Cancer Res. 87:349-356 (1996).
Tanaka T, Makita H, Kawamori T et al. Carcinogenesis. 18:1113-1118 (1997).

25 mg
100 mg
250 mg
$41.70
$156.30
$282.60
A0918 N-Acetyl-L-Cysteine    
  An antioxidant, that is effective in the early stages of carcinogenesis.

Bongers V, deJong J, Steen I, De Vries N, Bast A, Snow GB, Braakhuis B. J. Eur J. Cancer A(6):921-923 (1995).

10 g
25 g
$20.80
$36.00
A0920 N-Acetyl-S-(N'-phenethylthiocarbamoyl)-L-cysteine    
 

Phenethyl isothiocyanate N-acteyl-L-cysteine conjugate; PEITC N-acetyl-L-cysteine conjugate.<>br>An effective chemopreventive agent in mouse lung tumor bioassays and in other models.

25 mg
100 mg
500 mg
$67.20
$201.60
$784.00
A0819 Acetylsalicylic Acid / Aspirin    
 

Non-steroidal anti-inflammatory agent. Has undergone clinical trials as a chemopreventive agent.

Kelloff GJ, Boone CW, Crowell JA et al. Cancer Epidemiol. Biomarkers Prev 3:85-98 (1994).

500 g
1 kg
$34.40
$59.20
A0825 Ac-GPK-pNA    
 

 

25 mg
$680.00
A0826 Ac-GPK(Ac)-pNA    
 

 

25 mg
$680.00
A0832 Ac-IEAR-pNA    
 

 

25 mg $680.00
A0834 Ac-IETD-pNA    
 

 

25 mg
$680.00
A0833 Acipimox    
 

Acipimox inhibits lipolysis in peripheral tissues and induces large reduction in circulating serum-free fatty acids. The mechanism of triglyceride lowering appears to be an increase of VLDL-Tg clearance.

Nuutinen, J. Minn, H., Bergmand, J. et al Br. J. Cancer 80:513-518 (1999).
Hannah, J.S., Bodkin, NL., Paidi,, MS., et al. Acta Diabetol. 32:279-283 (1995).

1 g
5 g
10 g
$61.10
$237.30
$462.50
A0934 Acivicin    
-20 oC

A specific inhibitor of γ-glutamyl transpeptidase and transmembrane glutathione transport. Potent antitumor and antileishmania agent. It induces apoptosis in human lymphoblastoid cells.

Griffith, O.W. et al. Proc. Natl. Acad. Sci. USA 77:3384 (1980).
Earhart, R.H., et al. Adv. Enzyme Regulation. 24:179 (1986).
Mukherjee, T. et al. Biochem. Biophys. Res. Commun. 170:426(1982).
Graber, R., Losa, G.A. Int. J. Cancer. 62:443-8 (1995).

10 mg
25 mg
100 mg
$100.00
$160.00
$203.00
A0958 Aconitine    
4 oC A diterpene alkaloid isolated from Aconiti Carmichaeli Praeparata used to induce cardiac arrhythmias. It binds to neurotoxin binding site 2 of the alpha-sub-unit of the Na+ channel protein.

Telang BV, Ng'ang'a JN. Ind J Phy Pharm. 19:1-10 (1975). Ameri A. Prog Neurobiol. 56:211-235 (1998).
10 mg
25 mg
100 mg
$27.20
$47.50
$149.00
  Acrinol    
  See Ethacridine lactate monohydrate
   
A0960 ACTH (1-39), human    
 

Adrenocorticotropic hormone.

1 mg
$680.00
A0961 ACTH (1-39), rat    
 

Adrenocorticotropic hormone.

0.5 mg
1 mg
2.5 mg
$121.60
$206.40
$364.80
A0962 ACTH (1-4)    
 

Adrenocorticotropic hormone.

1 mg
2 mg
5 mg
$19.20
$32.00
$57.60
A0963 ACTH (1-10), human    
 

Adrenocorticotropic hormone.

1 mg
2 mg
5 mg
$25.60
$43.20
$76.80
A0964 ACTH (1-13), human    
 

Adrenocorticotropic hormone.

0.5 mg
1 mg
2.5 mg
$38.40
$65.60
$115.20
A0965 ACTH (1-14)    
 

Adrenocorticotropic hormone.

1 mg
2 mg
5 mg
$38.40
$65.60
$115.20
A0966 ACTH (1-16), human    
 

Adrenocorticotropic hormone.

0.5 mg
1 mg
2.5 mg
$44.80
$76.80
$134.40
A0967 ACTH (1-17), human    
 

Adrenocorticotropic hormone.

0.5 mg
1 mg
2.5 mg
$44.80
$76.80
$134.40
A0968 ACTH (1-24), human    
  Adrenocorticotropic hormone.
0.5 mg
1 mg
2.5 mg
$44.80
$76.80
$134.40
A0971 ACTH (4-10), human    
 

Adrenocorticotropic hormone.

1 mg
2 mg
5 mg
$32.00
$54.40
$96.00
A0970 ACTH (18-39), human    
  Adrenocorticotropic hormone.
1 mg
2 mg
5 mg
$83.20
$140.80
$249.60
A0977 Actinomycin D    
  Dactinomycin
An antibiotic from Streptomyces. Has antineoplastic activity.

Hennings H, Boutwell RK. Life Sci., 6:173-181 (1967).
Harris CC. Cancer. 37 (2 Suppl):1014-1023 (1976).
5 mg
10 mg
$73.20
$132.20
  Actinomycin D, 7-Amino    
  See 7-Amino-Actinomycin    
A0978 Actinonin    
  A naturally occurring antibacterial agent that is a potent peptide deformylase (PDF) inhibitor. It has shown dose-dependent antitumor effects on AKR leukemia in vivo.

Xu Y, Lai LT, Gabrilove JL, et al. Clinical Cancer Research. 4:171-6 (1998). Chen DZ, Patel DV, Hackbarth CJ et al. Biochemistry. 39:1256-62 (2000).
5 mg
25 mg
$70.60
$680.00
A1084 Ac-VEID-pNA    
    25 mg $680.00
A1096 Acycloguanosine    
  An orally active acyclic nucleoside with inhibitory activity towards several herpes viruses.

Elion GB et al. Proc Nat Acad Aci USA. 74:5716 (1977).
50 mg
100 mg
500 mg
$48.80
$87.90
$345.30
  Acyclovir    
  See acycloguanosine    
A1097 Ac-YVAD-pNA    
    25 mg $680.00
A1318 Adenine    
  Inhibits HL-60 cell growth by induction of apoptosis. Also induces
selective apoptosis toward MOLT4/HIV cells.

Tanaka Y, Yoshihara K, Tsuyuki M, Kamiya T. Exp. Cell Res. 213:242-52 (1994).
Hirasawa K, Yoshida O, Fujunami T et al. Biochem Biophys Res Commun. 273:1025-32 (2000).
10 g
25 g
$33.80
$61.50
A1319 Adenosine Triphosphate disodium    
  ATP
A P2 purinergic agonist, it increases activity of Ca2+ activated K+ channels.

Arkhammar P, Hallberg A, Kindmark H et al. Biochem J. 265:203-11 (1990).
Jaffar ZH, Pearce FL. Agents Actions. 40:18-27 (1993).

1 g
5 g
10 g
25 g
$22.00
$52.80
$85.80
$189.20
A1330 Adipokinetic Hormone    
  Adipokinetic hormones are neurohormones that regulate the metabolism of carbohydrates and lipids during flight and locomotion.

Stone, J.V. Mordue, W. Batley, K.E., Morris, H.R. Nature 263:207-211 (1976).
Robinson, NL., Goldsworthy, G.J. J. Insect Physiol 23:9-16 (1977).
1 mg
2 mg
5 mg
$32.00
$54.40
$96.00
A1330 Adipokinetic Hormone, AKH, locust    
    1 mg
2 mg
5 mg
$44.80
$76.80
$134.40
A1332 Adipokinetic Hormone II from Locusta migratoria    
  A grasshopper neuropeptide.

Noves BE, Schaffer MH. DNA Cell Biol. 12(6):509-516 (1993).
1 mg
2 mg
5 mg
$44.80
$76.80
$134.40
A1333 Adipokinetic Hormone II from Schistocera gregaria    
    1 mg
2 mg
5 mg
$44.80
$76.80
$134.40
A1368 Adrenomedullin (1-52), human    
  A potent vasodilating peptide found in human pheochromocytoma from the adrenal medulla. Intravenous administration of adrenomedullin resulted in a significant decrease in blood pressure along with total peripheral resistance.

Perret M. et. al. Life Sci. 53: 377-9 (1993).
Ishiyama Y. et. al. Eur J Pharmacol. 241:271-3 (1993).
0.5 mg
1 mg
2.5 mg
$403.20
$684.80
$1,209.60
A1369 Adrenomedullin (13-52), human    
    0.5 mg
1 mg
2.5 mg
$320.00
$544.00
$960.000
>A1369 Adrenomedullin (22-52), human    
    0.5 mg
1 mg
2.5 mg
$192.00
$326.40
$576.00
A1371 Adrenorphin    
    1 mg
2 mg
5 mg
$38.40
$65.60
$115.20
  Adriamycin    
  See doxorubicin HCl    
A1865 Aeroplysinin    
  A naturally occurring tyrosine metabolite from the marine sponge Verongia aerophoba. It has been shown to interfere with key events in angiogenesis, and displays a strong anti-tumor effect on epidermal growth factor dependent tumor lines. It has also shown antileukemic activity.

Rodriguez S, Gonzalez M, et al. FASEB Journal. 16:261-3 (2002).
Kreuter MH, Leake RE, et al. Comparative Biochem. 97:151-8 (1990).
Kreuter MH, Bernd A, et al. Journal of Biosciences. 44:680-8 (1989).
100 μg
5 x 100 μg
1 mg
$150.00
$600.00
$1,000.00
A2044 Aflatoxin B1    
  A potent hepatoxin and hepatocarcinogen oxidizes to form the carcinogenic, 2,3-exo-epoxide. Chronic exposure produces necrosis, cirrhosis, and carcinoma of the liver.

Phillips, T., Tox. Sci. (52 Suppl), 118-126 (1999). Daniels JM, Liu L, Stewart RK, Massey TE. Carcinogenesis. 5: 823-827 (1990).
1 mg
5 mg
$25.00
$100.00
A2046 Aflatoxin B2    
  A potent hepatoxin and hepatocarcinogen found in poorly stored grains and nuts. Chronic exposure is shown to produce mutagenesis, necrosis, and liver carcinogenesis.

Phillips, T., Tox. Sci. (52 Suppl), 118-126 (1999).
Daniels JM, Liu L, Stewart RK, Massey TE. Carcinogenesis. 5: 823-827 (1990).
1 mg
5 mg
$68.00
$330.00
A2048 Aflatoxin G1    
  A mycotyxin produced by aspergillus parasiticus. A toxic and carcinogenic mycotoxin that induces mutation of human chromosomes by forming guanyl-N7 adducts in liver DNA.

el-Zawahri MM, Morad MM, Khishin AF. J Environ Pathol Toxicol Oncol. 10:45-51 (1990).
Baertschi SW, Raney KD, Shimada T, Harris TM, Guengerich FP. Chem Res Toxicol. 2:114-2 (1989).
1 mg
5 mg
$70.00
$340.00
A2050 Aflatoxin G2    
  A mycotyxin produced by aspergillus parasiticus. Binds to DNAse II, exhibits inhibition effects.

Lotter LH, Schabort JC. Int J Biochem. 15:817-25 (1983).
1 mg
5 mg
$168.00
$540.00
A2052 Aflatoxin M1    
  A potent hepatotoxic mycotyxin metabolite of Aflatoxin B1. Often found in milk of cattle fed on AfB1 contaminated feed. Exhibits cytotoxic activities.

Neal G, Eaton D, Judah D, Verma A. Toxicol Appl Pharmacol. 151:1582-8 (1998).
100 µg
1 mg
$54.00
$316.00
A2054 Aflatoxin M2    
  Metabolite of Aflatoxin B2, which is found in milk of cattle fed on AfB2.

Purchase, I, Food Cosmet Toxicol. 5:339-42 (1967).
100 µg
1 mg
$136.00
$956.00
A2412 A-G-D-V    
  A mycotyxin produced by aspergillus parasiticus. A toxic and carcinogenic mycotoxin that induces mutation of human chromosomes by forming guanyl-N7 adducts in liver DNA.

el-Zawahri MM, Morad MM, Khishin AF. J Environ Pathol Toxicol Oncol. 10:45-51 (1990).
Baertschi SW, Raney KD, Shimada T, Harris TM, Guengerich FP. Chem Res Toxicol. 2:114-2 (1989).
5 mg
10 mg
25 mg
$96.00
$163.20
$288.00
A4369 A-K-R-R-R-L-S-S-L-R-A    
  A mycotyxin produced by aspergillus parasiticus. Binds to DNAse II, exhibits inhibition effects.

Lotter LH, Schabort JC. Int J Biochem. 15:817-25 (1983).
1 mg
2 mg
5 mg
$38.40
$65.60
$115.20
A4401 A-L-A-L    
  A potent hepatoxin and hepatocarcinogen oxidizes to form the carcinogenic, 2,3-exo-epoxide. Chronic exposure produces necrosis, cirrhosis, and carcinoma of the liver.

Phillips, T., Tox. Sci. (52 Suppl), 118-126 (1999). Daniels JM, Liu L, Stewart RK, Massey TE. Carcinogenesis. 5: 823-827 (1990).
1 mg
2 mg
5 mg
$12.80
$22.40
$38.40
A4400 Alamethicin    
  Alamethicin is a channel-forming ionophore. It activates membrane enzymes by disrupting the membrane barriers of sarcolemmal vesicles, which gives substrates and activators access to enzymatic sites in the interior of the vesicles.

Jones, L.R., Maddock, S.W., Besch , H.R. Jr. J. Biol. Chem. 255:9971-9980 (1980).
1 mg
5 mg
$34.00
$138.00
A4402 L-Alaninol    
  An amino acid alcohol with anti-proliferative effect.

Landau O, Wasserman L, Deutsch AA. Cancer Lett. 69:203-8 (1993).
1 g
10 g
$29.60
$203.30
A4403 Alarelin Acetate    
  A gonadotropin-releasing hormone analogue shown to inhibit DNA synthesis and poliferation of rat gastric smooth muscle cells through GnRH receptors in vitro.

Chen L, He HX, Sun XD, Zhao J, Liu LH, Huang WQ, Zhang RQ. World J Gastroenterol. 10:1780-4 (2004).
  Please inquire
A4606 Albendazole    
RT Methyl-5(propylthio)-2-benzimidazolecarbamate
10 g
50 g
$45.60
$159.10
  Albendazole sulfoxide    
  See Ricobendazole
   
A4508 Alclofenac    
  A non-steroidal anti-inflammatory agent, commonly used in the treatment of rheumatoid arthritis. 5 g
25 g
100 g
$35.90
$112.00
$336.00
A4515 Alendronate Monosodium Trihydrate    
  A second generation bisphosphonate used as bone resorptive inhibitor. It induces apoptosis of rabbit osteoclasts, human osteoclastoma-derived isteiclasts and human osteollclast-like cells in vitro. The promotion of apoptosis of OCLs is related to the expression of FAS gene.

Woo T, Adachi JD. Baillieres Best Pract Res. Clin Rheumatol. 15:469-81 (2001).
Benford HL, McGowan NW, Helfrichg MH et al. Bone 28:465-73 (2001).
Wang XM, Yu SF, Yang ZP. Chin J Dent Res. 3:26-32 (2000).
100 mg
500 mg
$45.60
$159.10
A4521 Alfacalcidol    
  A bone resorption inhibitor. Has shown antitumor activity in non-Hodgkin's lymphomas.

Cunningham D, Gilchrist NL, Cowan RA et al. Brit Med J Clin Res. 291:1153-1155 (1985).
Shiraki M, Fukuchi M, Kiriyama T. J Bone Miner Metab. 22:352-359 (2004).
1 mg
5 mg
$89.60
$364.00
A4438 Allotostatin I    
  A neuropeptide that inhibits juvenile hormone synthesis in insects. Its inhibitory regulation of intestinal muscles, it was also found to modulate skeletal neuromuscular events.

Woodhead, AP., Stay, B, Seidel, SL, et al Proc. Natl. Acad. Sci.USA 86:5997-6001 (1989).
Kreissl, S. Weiss, T., Djokaj, S. Et al. Eur. J. Neurosci. 11:2519-2530 (1999).
1 mg
2 mg
5 mg
$44.80
$76.80
$134.40
A4440 Allicin    
  10 mg/ml methanol/water/formic acid (60:40:0.1)
The main biologically active compound in garlic. It exerts various biological effects, including antiproliferative, chemopreventive, antioxidant, antihyperlipidaemic and antihypertensive effects. It has been shown to inhibit the growth of cancer cells of murine and human origin in addition to inhibiting telomerase activity and inducing apoptosis in gastric SGS-7901 cells.

Sela U, Ganor S, Hecht I et al. Immunology. 11:391-9 (2004).
Oommen S, Anto RJ, Srinivas G et al. Eur J Pharmacol. 485:97-103 (2004).
Sun L, Wang X. World J Gastroenterol. 9:1930-4 (2003).
1 mg
5 mg
$145.80
$512.30
A4443 L(+) Alliin    
  3-(2-Propenylsulfinyl) alanine
Optically pure form of alliin
25 mg
50 mg
100 mg
$138.70
$234.80
$426.40
A4444 L(±) Alliin    
  3-(2-Propenylsulfinyl) alanine.
Racemic mixture.
100 mg
500 mg
1 g
$72.00
$295.80
$476.30
A4445 Allopurinol    
  An isomer of hypoxanthine. It is a potent xanthine oxidase inhibitor.

Kelley WN, Beardmore TD. Science, 169:388-390 (1970).
Marchmont RJ, Houslay MD. Biochem J. 195:653-660 (1981).
Weber G, Prajda N. Adv Enz Reg. 34:71-89 (1994).
5 g
10 g
$15.10
$27.30
A4547 Alloxan Monohydrate    
 

2,4,5,6(1H,3H)-pyrimidinetetrone monohydrate
It is a cytotoxic compound which causes oxidative base damage to nuclear and mtDNA. It also inhibits pancreatic cancer by selectively destroying pancreatic islet cells, and gall bladder cancer.

Driggers WJ, Holmquist GP, LeDoux SP, Wilson GL. Nucleic Acids Res 25:4362-9 (1997).
Pour PM. Frontiers in Bioscience 2:271-282 (1997).
Pour PM, Donnelly K, Stepan K. Am J Pathology 110:310-4 (1983).

5 g
10 g
25 g
$14.70
$26.10
$49.20
  S-Allyl-L-cysteine    
  See L-Deoxyalliin    
A4544 Allyl Disulfide    
  Garlic constituent. Known to have anticarcinogenic and antimicrobial activity. It inhibits human tumor cell proliferation, induces apoptosis in human colon tumor cells and selectively kills HIV-1-infected cells.

Reddy S, Rao CV, Rivenson A, Kelloff G. Cancer Res. 35:3493-8 (1993).
Sundaran SG, Milner JA. Biochim Biophys Acta. 1315:15-20 (1996).
Sundaran SG, Milner JA. Carcinogenesis. 17:669-73 (1996).
Shoji S, Furuishi K, Yanase R et al. Biochem Biophys Res Commun. 194:610-21 (1993).
500 mg
1 g
5 g
$62.90
$118.80
$530.50
A4577 Alsterpaullone    
  The most active paullone. It is a potent inhibitor of glycogen synthase kinase-3 and cyclin - dependent kinase 5/p25. It has been shown to induce apoptosis and promote loss in clonogenicity in the Jurkate cell line.

Leost M, Schultz C, Link A et al. European J Biochem. 267:5983-94 (2000).
Lahusen T, De Siervi A, Kunick C et al. Molecular Carcinogenesis. 36:183-94 (2003).
1 mg
5 mg
$98.80
$444.60
A4578 Altretamine    
  An antineoplastic agent. Active in ovarian cancer, lymphomas, bronchogenic carcinoma, and carcinoma of the breast.

Lake LM, Grunden EE, Johnson BM. Cancer Res. 35:2858-63 (1975).
Legha SS, Slavik M, Carter SK. Cancer. 38:27-35 (1976).
500 mg
1 g
5 g
$49.30
$74.00
$301.90
A4496 Alyssin, 97%    
4 oC Homolog of sulforaphane.
25 mg
50 mg
100 mg
500 mg
$93.10
$161.60
$290.90
$977.40
A4497 Alyssin sulfone, 97%    
4 oC   25 mg
50 mg
100 mg
500 mg
$85.80
$143.10
$257.40
$867.30
A4498 Alytesin    
  A neuropeptide isolated from amphibian skin that stimulates gastric acid secretion, intestinal contraction and hypertension in dogs.

Anastasi et. al. Experientia. 27:166-7 (1971).
1 mg
2 mg
5 mg
$32.00
$54.40
$96.00
A4802 Amantadine Hydrochloride    
  An antiviral drug. Inhibits ion channels of influenza, and disrupts T-cell development.

Griffin SD, Beales LP, Clarke DS et al. FEBS Lett. 535:34-8 (2003).
Smith CA, Graham CM, Mathers K et al. Immunology. 105:306-13 (2002).
25 g
100 g
$51.80
$166.40
A4803 Amantadine Sulfate    
    25 g
100 g
$51.80
$166.40
A4805 Amastatin Hydrochloride    
  An inhibitor of aminopeptidase, shown to prolong the effect of both vasopressin and oxytocin.

Meisenberg G, Simmons WH. Peptides. 5:535-9 (1984).
Chen X, Pittman QJ. J Neurophysiol. 82:1689-96 (1999).
1 mg
5 mg
10 mg
$89.60
$296.80
$537.60
A4806 Ambroxol Hydrochloride    
  A metabolite of bromhexine that is a mucolytic agent. It prevents neutrophil-mediated A1AT inactivation via inhibition of HOCl production as well as HOCl scavenging, in addition to inhibiting proinflammatory cytokines.

Su X, Wang L, Song Y et al. Intens Care Med. 30:133-40 (2004).
Ottonello L, Arduino N, Bertolotto M et al. Brit J Pharmacol. 140:736-42 (2003).
Sepulveda J, Velasquez BJ. Respiration. 43:363-88 (1982).
1 g
5 g
25 g
$25.00
$45.00
$150.00
  L-(+)-Amethopterin Dihydrate    
  See Methotrexate
   
A4933 Amifostine    
  Aminopropyl aminoethylthiophosphate
Amifostine is a chemoprotective drug used to selectively protect normal tissues from the side effects of chemotherapeutic drugs such as cyclophosphamide, mitomycin-C and cisplatin, and ionizing radiation therapy.

Culy CR, Spencer CM. Drugs 61:641-84 (2001).
Grdina DJ, Kataoka Y, Murley JS. Drug Metabol Drug Interact 16:237-79 (2000).

50 mg
100 mg
500 mg
$66.00
$117.10
$439.10
A5132 Amikacin Disulfate    
  An aminoglycoside antibiotic derived from Kanamycin A.

Danhauer FJ, Fortner CL, Schimpff SC et al. Clin Pharm. 1:539-43 (1982).
Guy H, Chavanet P, Portier H, et al. Nouv Presse Med. 10:654-6 (1981).
250 mg
1 g
5 g
$29.60
$74.00
$246.40
A5133 Amiloride HCl    
  Potassium-sparing diuretic.

Baer JE, Jones CB, Spitzer SA, Russo HF. J Pharmacol Exp Ther 157:472-85 (1967).
500 mg
1 g
5 g
$24.70
$33.30
$120.80
A4930 7-Amino-actinomycin D    
  A reagent used as a cytochemical probe. It forms complexes with DNA in solution resulting in shifts of both the excitation and emission wavelengths. It has been used successfully to identify apoptosis.

Gill, J.E.; Jotz, M.M.; Young, S.G et al. J Histochem & Cytochem. 23:793-799 (1975).
Philpott, N.J., Turner, A.J., Scopes, J. et al. Blood 87:2244-2241 (1996).
1 mg
5 mg
$72.00
$360.00
A4931 3-Aminobenzamide    
  A poly (ADP-ribose) Polymerase (PARP) inhibitor, a stress response protein activated by cytotoxic agents and makes cells resistant to apoptosis. It inhibits the modification of specific sites in replicating DNA. It also stimulates repair replication after exposure to alkylating agents

Lee YJ, Shacter E. J Biol Chem. 274:19792-8 (1999).
Kurian P, Kumari HL, Milo GE. Carcinogenesis. 13:489-91 (1992).
Cleaver JE. Carcinogenesis. 17:1-3 (1996).
100 mg
250 mg
500 mg
$44.40
$86.00
$231.80
  γ-Amino-n-butyric acid    
  See GABA
   
A4935 6-Aminocaproic acid    
  A protease inhibitor with chemopreventive properties. It inhibits chemically induced carcinogenesis of the esophagus, peripheral nerve, brain and kidney in experimental animals.

Bespalov VG, Aleksandrov VA, Petrov AS, Troian DN. Vopr Onkol. 38(1):69-74. (1992).
Alexandrov VA, Bespalov VG, Petrov AS, Troyan DN, Lidaks MYu. Carcinogenesis. 17(9):1935-9 (1996).
10 g
100 g
$15.30
$23.20
A5032 D,L-Aminoglutethimide    
  3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione
An adrenocortical suppressant which also inhibits conversion of androgens to estrogens by the aromatase enzyme system. Reduces tumor multiplicity and increases latent period of MNU-induced mammary tumorigenesis.

Pelissero C, Lenczowski MJ, Chinzi D et al. J Steroid Biochem Mol Biol. 57:215-23 (1996).
Moon RC, Steele VE, Kelloff GJ et al. Anticancer Res. 14:889-93 (1994).
500 mg
1 g
$46.10
$76.90
A4940 6-Aminonicotinamide    
 

Induces apoptosis in tumor cells. Member of the drug combination called PMA which induces regression of murine mammary tumors by depleting ATP.

Ogata S, Takeuchi M, Fujit, H et al. Biosci Biotechnol Biochem 64:327-332 (2000).
Nord, L.D., Stolfi, R.L., Alfieri, A.A., et al Cancer Chemother Pharmacol. 40:376-384 (1997).
Colofiore JR, Stolfi RL, Nord LD, Maartin DS. Biochem Pharmacol 50:1943-8 (1995).

1 g
5 g
$98.00
$400.00
A5001 Aminopterin    
  4-Aminofolic acid
An inhibitor of dihydrofolate reductase shown to induce apoptosis mouse HGPRT(-) myeloma cell lines.

Chung YH, Youn J, Choi Y et al. Immunol Lett. 77:127-31 (2001).
Kremer P, Hartung G, Bauder-Wust U et al. Anticancer Drugs. 13:615-23 (2002).
25 mg
100 mg
500 mg
$76.20
$235.20
$800.80
A5030 4-Aminophenylphosphate monosodium salt, 98%    
  Substrate for the electrochemical measurement of alkaline phosphatase.

Frew JE, Foulds NC, Wilshere JM, Forrow NJ, Green MJ. J. Electroanal. Chem., 266:309-316 (1989).
10 mg
50 mg
100 mg
$42.90
$145.90
$262.40
A5134 Aminophylline Anhydrous    
  The water soluble complex of Theophyline. A non-selective phosphodiesterase inhibitor.

Noguchi Y, Ito M, Katsumi K et al. Gastroenterol Jpn. 21:129-34 (1986).
Reddy SV, Maderdrut JL, Yaksh TL. J Pharmacol Exp Ther. 213:525-33 (1980).
25 g
100 g
500 g
$43.20
$61.60
$184.80
A5135 Aminophylline Dihydrate    
    25 g
100 g
500 g
$34.50
$43.20
$104.80
A5033 4-Aminosalicylic acid    
  p-Aminosalicylic acid
An antituberculous agent. Effective in treatment of distal ulcerative colits.

Oda N, Matsumoto K. Yakushigaku Zasshi 36:161-6 (2001).
O'Donnell LJ, Arvind AS, Hoang P et al. Gut. 33:947-9 (1992).
25 g
100 g
500 g
$12.40
$22.20
$98.60
A5034 4-Aminosalicylic acid sodium dihydrate    
  p-Aminosalicylic acid sodium salt
Sodium salt of p-Aminosalicylic acid.
25 g
100 g
500 g
$12.40
$19.80
$92.40
A5035 5-Aminosalicylic acid    
  Mesalazine; mesalamine
The active metabolite of Sulphasalazine. Effective in remission of Crohn's disease.

Rhodes JM, Bartholomew TC, Jewell DP. Glut. 22:642-7 (1981)
Modigliani R, Colombel JF, Dupas JL et al. Gastroenterology 110:688-93 (1996).
25 g
100 g
$61.60
$160.20
A5037 Amiodarone Hydrochloride    
  Formamidine pesticide with carcinogenic potential. It has been shown that amitraz-induced mydriasis is mediated by postsynaptic alpha 2-adrenoreceptors while amitraz-induced bradycardia is mediated by presynaptic alpha 2-adrenoreceptors.

Moser VC, MacPhail RC. Toxicol Lett. 28:99-104 (1985).
Hsu WH, Kakuk TJ. Toxicol Appl Pharmacol 73:411-5 (1984).
1 g
5 g
10 g
$37.00
$98.60
$308.00
A5039 Amitraz    
  Formamidine pesticide with carcinogenic potential. It has been shown that amitraz-induced mydriasis is mediated by postsynaptic alpha 2-adrenoreceptors while amitraz-induced bradycardia
is mediated by presynaptic alpha 2-adrenoreeptors.

Moser VC, MacPhail RC. Toxicol Lett. 28:99-104 (1985).
Hsu WH, Kakuk TJ. Toxicol Appl Pharmacol 73:411-5 (1984).
5 g
25 g
100 g
$37.00
$98.60
$308.00
A5045 Amlodipine    
 

A calcium channel antagonist with potent antioxidant activity. It inhibits doxorubicin-induced myocyte apoptosis by supressing the mitochondrial apoptotic pathway. It has been found to inhibit hyperplasia and hypertrophy in mesangial cells.

Yamanka S, Tatsumi T, Shiraishi J et al. J Am Coll Cardiol. 41:870-8 (2003).
Shultz PJ, Raij L. Am J Hypertens. 5:912-4 (1992).

1 g
5 g
10 g
$37.00
$141.70
$184.80
A5044 Amlodipine besylate
   
  A calcium channel blocker commonly used in the treatment of hypertension and angina. It also has shown antireproductive effects in male rats: a reduction in sperm density, the amount of mature spermatids, and the number of Sertoli cells.

Almeida SA, Teofilo JM, Anselmo JA et al. Exp Toxicol Pathol. 52:353-6 (2000).
1 g
5 g
10 g
$39.50
$145.40
$194.70
A5057 Amoxicillin    
  A semi-synthetic antibiotic similar to penicillin.

Kochi T, Tachimori Y, Itoh N et al. Jpn J Antibiot. 34:1395-400 (1981).
Brogeden RN, Speight TM, Avery GS. Drugs. 9:88-140 (1975).
5 g
25 g
100 g
$28.00
$50.40
$151.20
A5130 Amphotericin B    
  A polyene antibiotic produced by Streptomycetes nodosus that has shown antitumor activity.

Presant CA, Metter GE, Multhauf P et al. Cancer Treat Rep. 68:651-4 (1984).
Medoff J, Medoff G, Goldstein MN et al. Cancer Res. 35:2548-52 (1975).
100 mg
250 mg
500 mg
1 g
$39.20
$65.00
$112.00
$168.00
A5160 Ampicillin Trihydrate    
  An antibiotic. It is a semi-synthetic penicillin.

Visuri T, Antila P, Laurent LE. Ann Chir Gynaecol Suppl. 65:58-61 (1976).
5 g
25 g
100 g
$27.80
$67.80
$184.80
A5161 Ampiroxicam    
  A prodrug of piroxicam with reduced gastrointestinal irritation. It is a non-steroidal anti-inflammatory agent proven to be an effective chemopreventive.

Olkkola KT, Brunetto AV, Mattila MJ. Clin Pharmacokinet. 26:107-20 (1994).
Carty TJ, Marfat A, Moore PF et al. Agents Actions. 39:157-65 (1993).
1 g
5 g
25 g
$30.80
$80.10
$326.50
A5162 Amprolium Hydrochloride    
  A coccidiostat mainly used in poultry feed. It inhibits the sporulation of the oocysts of several common strains of coccidia.

Joyner, LP., Norton, CC. Parasitology 75:155-164 (1977).
25 g
100 g
$27.20
$92.20
A5170 Amrinone    
  Selective phosphodiesterase III inhibitor. A nonglycoside, noncatecholamine agent with positive inotropic effect. Inhibits cyclic AMP-dependent protein kinase activity by competing with ATP
but not cyclic AMP binding sites. It also inhibits platelet aggregation and induces disaggregation.

Ono S, Ueda S, Sakuma T et al. J Cardiov. Surgery 37:177-81 (1996).
Earl CQ, Linden J, Weglicki WB. Life Sciences 39:1901-8 (1986).
Kikura M, Kazama T, Ikeda T et al. Platelets 11:446-58 (2000).
250 mg
1 g
$37.00
$98.60
A5193 Amygdalin    
  A benzylic glycoside that has been used as an antineoplastic agent.

Fukuda T, Ito H, Makainaka et al. Biol Pharm Bull. 26:271-273 (2003).
Stock CC, Martin DS, Sugiura K et al. J Surgical Oncology. 10:89-123 (1978).
1 g
5 g
25 g
$22.40
$33.60
$134.40
A4844 Amylin (8-37), human    
  Putative polypeptide hormone from type 2 human diabetes and adult diabetic cats which consists of 37-amino acid peptide subunit of amyloid.

Edwards, B. J.; Morley, J. E. Life Sci. 51:1899-1912 (1992).
0.5 mg
1 mg
2.5 mg
$172.80
$33.60
$518.40
A4845 Amylin (8-37), rat    
    0.5 mg
1 mg
2.5 mg
$172.80
$33.60
$518.40
A4846 Amylin (IAPP)(Feline)    
    0.5 mg
1 mg
2.5 mg
$185.60
$315.20
$556.80
A4847 Amylin, human    
  A member of the calcitonin family of hormones that is co-secreted with insulin from the pancreas during and after food intake. It inhibits RINm5F islet beta-cell proliferation and evokes apoptosis associated with typical degenerative ultrastructural changes and DNA fragmentation.

Zhang S, Liu J, Saafi EL et al. FEBS Lett. 455:315-20 (1999).
Riediger T, Zuend D, Becskei C et al. Am J Physiol Regul Integr Comp Physiol. 286:R114-22 (2004).
0.5 mg
1 mg
2.5 mg
$103.10
$174.80
$309.20
A4850 Amylin, rat    
  Putative polypeptide hormone from type 2 human diabetes and adult diabetic cats which consists of 37-amino acid peptide subunit of amyloid.

Edwards, B. J.; Morley, J. E. Life Sci. 51:1899-1912 (1992).
0.5 mg
1 mg
2.5 mg
$147.20
$249.60
$441.60
A4851 β-Amyloid (1-40), rat    
  A protein that stimulates the release of nitric oxide in neuronal cell lines. It often forms the neurotoxic peptide deposits associated with Alzheimer's disease and aging.

Hu J, el-Fakahany EE. Neuroreport. 4(6):760-762 (1993).
0.5 mg
1 mg
2.5 mg
$211.20
$358.40
$633.60
A4853 β-Amyloid (1-40), Ultra Pure, TFA    
    0.5 mg
1 mg
2.5 mg
$211.20
$358.40
$633.60
A1330 β-Amyloid (1-42), human    
    0.5 mg
1 mg
2.5 mg
$211.20
$358.40
$633.60
A4849 β-Amyloid (25-35)    
  The 11-residue functional domain of Amyloid-b protein. 1 mg
2 mg
5 mg
$27.80
$67.80
$184.80
A4854 β-Amyloid Peptide (1-42), rat    
    1 mg
2 mg
5 mg
$236.80
$403.20
$710.40
A4848 Amyloid-β Protein    
  A protein that stimulates the release of nitric oxide in neuronal cell lines. It often forms the neurotoxic peptide deposits associated with Alzheimer's disease and aging.

Hu J, el-Fakahany EE. Neuroreport. 4(6):760-762 (1993).
1 mg $322.60
A5202 Anabasine hydrochloride    
  An anabisis aphylla alkaloid with antialcoholic effects. It has been shown to suppress breast cancer aromatase activity.

Kadohama N, Shintani K, Osawa Y. Cancer Lett. 75:175-82 (1993).
Mirzaez S. Farmakol Toksikol. 41:52-5 (1978).
25 mg
100 mg
$24.70
$64.10
A5302 Anastrozole    
  A selective aromatase inhitor used to treat hormone-responsive metastic breast cancer. It may be effective against recurrent ovarian adult granluosa cell tumors.

Plourde, PV., Dyroff, M., Dowsett, M. et al. J. Steroid Biochem. Mol. Biol 53:175-179 (1995).
Edwards, B. J.; Morley, J. E. Life Sci. 51:1899-1912 (1992).
100 mg
250 mg
1 g
$68.00
$125.00
$380.00
A5313 Andrographolide    
  Andrographolide is from Andrographis paniculata. It inhibits PAP-induced human blood platelet aggregation, inhibits nitrite synthessis in macrophage, and restores vasocontractile response in thoracic aorta.

Amroyan E, Gabrielian E, Panossian A et al. Phytomedicine 6:27-31 (1999).
Chiou WF, Lin JJ, Chen CF. Br. J. Pharmacol. 125:327-334 (1998).
1 mg
5 mg
10 mg
$61.50
$223.00
$325.70
A5314 Andrographolide, dehydro-    
 

1 mg
5 mg
10 mg
$61.50
$223.00
$325.70
A5315 Andrographolide, deoxy-    
  Anti-inflammatory drug, isolated from Andrographis paniculata Nees. A potent cell differentiation-inducer of M1 cells.
Shen YC, Chen CF, Chiou WF. Planta Med. 66:314-7 (2000).

Matsuda T, Kuroyanagi M, Sugiyama S et al. Chem Pharm Bull 42:1216-25 (1994).
1 mg
5 mg
10 mg
$61.50
$223.00
$325.70
A5217 trans-Anethole    
  Induces Phase II drug-metabolizing enzymes. Potential anti-carcinogen in tumor cells.

Rompelberg CJ, Verhagen H, van Bladeren PJ. Food Chem Toxicol., 31:637-645 (1993).
al-Harbi MM, Qureshi S, Raza M et al. Eur J Cancer Res. 4:307-318 (1995).
50 ml
100 ml
$47.00
$81.10
A5219 Anethole-trithione    
  Analog of the chemopreventive agent oltipraz. It was shown to increase cholinergic and adrenergic responsiveness in rats. Mechanism may act by stimulating some post-receptor effect in the coulping to the secretory response.

Lubet RA, Steele VE, Eto I et al. Int J Cancer. 72:95-101 (1997).
Glenert U. Eur J Pharmacol. 226:43-52 (1992).
25 mg
100 mg
500 mg
$55.50
$178.70
$616.00
A5225 α-ANF(1-28), human    
  The major form of atrial natriuretic peptide in circulation throughout the body. Modulates saline and fluid balance in the blood by stimulating renin release.

Hisa H, Tomura Y, Satoh S. Am J Physiol. 257(3 Pt 1): E332-335 (1989).
0.5 mg
1 mg
2.5 mg
$172.80
$294.40
$518.40
A5228 Angiogenin    
  Mol. Wt. ~14,000 Da
An endogenous single chain protein that induces the formation of blood vessels.

Fett JW. Biochemistry 24:5480 (1985).
Shapiro R. Biochemistry 26:5141 (1987).
50 μg $1,121.90
A5230 Angiostatin    
  A 38-kD fragment of plasminogen that is a potent endothelial cell growth inhibitor. It has been shown to inhibit angiogenesis in vivo and tumor growth in mice.

O'Reilly MS, Holmgren L, Chen C et al. Cell. 79:315-28 (1994).
Scappaticci FA, Smith R, Pathak A et al. Molecular Therapy. 3:186-96 (2001).
0.5 mg $635.10
A5070 Angiotensin Acetate    
  Please inquire
A5272 Angiotensin, Canine, rat    
  5 mg
10 mg
25 mg
$44.80
$76.80
$134.40
A5273 Angiotensin Converting Enzyme Inhibitor    
    5 mg
10 mg
25 mg
$25.60
$43.20
$76.80
A5275 Angiotensin I [Des-Asp1-], human    
    5 mg
10 mg
25 mg
$19.20
$32.00
$57.60
A5276 Angiotensin I, human    
  The decapeptide precursor to angiotensin II.

5 mg
10 mg
25 mg
$19.20
$32.00
$57.60
A5277 Angiotensin II, human
   
  A vasoactive agent that acts on the adrenal gland to stimulate the release of aldosterone.

Wallace KB, Roth RA, Hook JB et al. Am J Physiol. 238:R395-399 (1980).
5 mg
25 mg
$32.00
$112.00
A5279 Angiotensin II (1-4), human    
  5 mg
10 mg
25 mg
$32.00
$54.40
$96.00
A5280 Angiotensin II (3-8), human    
  5 mg