| A0099 |
A-779 |
1 mg |
$64.50 |
| |
C39H60N12O11 FW 872.99 |
2 mg |
$109.30 |
| |
A potent and selective antagonist for the heptapeptide angiotensin- |
5 mg |
$193.50 |
| |
(1-7)[ANG-(1-7)]. It prevents ANG-(1-7)-induced inhibition of angiogenesis. |
|
|
| |
Santos, R.A; Campagnole-Santos, M.J.; Baracho, N.C., et.al. Brain Res. Bull 35:293-298 (1994). |
|
|
| |
Machado,R.D.;Santos,R.A.,Andrade,S.P.Amer.JPhysio-Reg. Integ.&Comp.Physio280:R994-RR1000(2001). |
|
|
| |
| |
A23187, Free acid (See Calcimycin C0246) |
|
|
| |
| A0101 |
A23187, 4-Bromo |
1 mg |
$80.60 |
| |
4-Bromo-A-23187, 4-BrA23187, 4-Bra23187 |
5 mg |
$329.30 |
| |
C29H36BrN3O6 FW 602.52 [76455-82-8] |
|
|
| |
A halogenated analogue of A23187. It is a nonfluorescent Ca2+ ionophore used in calibration |
|
|
| |
for determining cytoplasmic Ca2+ by fluorescent probes. |
|
|
| |
Deber CM., Tom-Kun J., Mack E., Grinstein S. Anal Biochem 146: 349-352 (1985) |
|
|
| |
| A0102 |
A23187, Ca-Mg |
5 mg |
$60.50 |
| |
(C29H36N3O6)2Mg, (C29H36N3O6)2Ca FW: 523.62 |
10 mg |
$112.00 |
| |
A calcium, magnesium salt of A23187, a calcium ionophore used to increase intracellular |
|
|
| |
calcium levels in cells. |
|
|
| |
Mickelson et.al. Arch Biochem Biosphys. 242: 127-136 (1985). |
|
|
| |
Andersson D, Zygmunt P, Movahed P, Anderson T, Hogestatt E. Br J Pharmacol. 129: 1490-6 (2000)0 |
|
|
| |
| A0025 |
17-AAG |
0.5 mg |
$226.60 |
| |
17-(Allylamino)-17-desmethoxy-geldanamycin; allylaminogeldanamycin |
1 mg |
$307.30 |
| |
C31H43N3O8 FW 585.69 [75747-14-7] |
|
|
| |
An anologue of geldanamycin. It is a Hsp90 antagonist that induces apoptosis in human leukemia |
|
|
| |
cells. It has been shown to enhance paclitaxel-mediated cytotoxicity and downregulate vascular |
|
|
| |
endothelial factor expression. |
|
|
| |
Rahmani M, Yu C, Dai Y et al. Cancer Research. 63:8420-7 (2003). |
|
|
| |
Nguyen DM, Lorang D, Chen GA et al. Annals of Thoracic Surgery. 72:371-8 (2001). |
|
|
| |
| A0501 |
Abamectin |
1 g |
$31.40 |
| |
[71751-41-2] |
5 g |
$106.60 |
| |
An insecticide and antihelmintic agent made up of a mixture of avermectins. |
25 g |
$407.70 |
| |
Lasota JA, Dybas RA. Acta Leidensia. 59:217-225 (1990) |
|
|
| |
Ali A, Nayar JK. J Am Mosquito Control Assoc. 1:384-386 (1985). |
|
|
| |
| A0802 |
Acarbose |
1 g |
$44.20 |
| |
C25H43NO18 FW 645.60 [56180-94-0] |
5 g |
$172.50 |
| |
An a-glucosidase inhibitor that inhibits sucrose digestion in rats. |
25 g |
$689.90 |
| |
It has been found to reduce the risk of cardiovascular disease and hypertension. |
|
|
| |
Krause HP, Keup U, Puls, W. Digestion. 23:486-94 (1982). |
|
|
| |
Chiasson JL, Josse RG, Gomis R et al. JAMA. 23:486-94 (2003). |
|
|
| |
| A0812 |
Ac-D-E |
5 mg |
$35.80 |
| |
C11H16N2O8 FW 304.3 |
10 mg |
$60.90 |
| |
| A1017 |
Aceclofenac |
5 g |
$44.20 |
| |
C16H13Cl2NO4 FW 354.18 [89796-99-6] |
25 g |
$172.50 |
| |
A non-steroidal anti-inflammatory drug. It possesses potent inhibitory activity |
100 g |
$517.40 |
| |
in several models of acute and chronic inflammation. It has a more favorable therapeutic |
|
|
| |
ratio compared to indomethacin, diclofenac, naproxen, and phenylbutazone. |
|
|
| |
Yamazaki R, Kawai S, Matsuzaki T et al. Eur J Pharmacol. 329:181-7 (1997). |
|
|
| |
Grau M, Guasch J, Montero JL et al. Arzneimittelforschung. 41:1265-76 (1991). |
|
|
| |
| A0816 |
Acemetacin |
1 g |
$24.40 |
| |
C21H18ClNO6 FW 415.82 [53164-05-9] |
5 g |
$75.90 |
| |
A derivative of indomethacin. Used as an anti-inflammatory drug. It is as potent as indomethacin |
|
|
| |
as an inhibitor of COX-2, but less active on COX-1. It has been found to have anti-tumor activity in |
|
|
| |
the colon of mice. |
|
|
| |
Tavares IA, Bennett A. Int. J Tisssue Reactions. 15:49-53 (1993). |
|
|
| |
Kisara S, Maekawa I, Sasaki K et al. Res. Comm. Chem Path. Pharm. 81: 247-250 (1993). |
|
|
| |
| A0817 |
D,L-1'-Acetoxychavicol Acetate |
25 mg |
$46.70 |
| |
C13H14O4 FW 234.25 [52946-22-2] |
100 mg |
$175.10 |
| |
A xanthine oxidase inhibitor shown to possess chemopreventive |
250 mg |
$316.50 |
| |
potential against both oral and colonic tumorigenesis in rats. |
|
|
| |
Ohnishi M, Tanaka T, Makita H et al. Jpn J Cancer Res. 87:349-356 (1996). |
|
|
| |
Tanaka T, Makita H, Kawamori T et al. Carcinogenesis. 18:1113-1118 (1997). |
|
|
| |
| A0918 |
N-Acetyl-L-Cysteine |
10 g |
$23.30 |
| |
C5H9O3S FW 163.19 m.p. 109-111oC [616-91-1] |
25 g |
$40.30 |
| |
An antioxidant, that is effective in the early stages of carcinogenesis. |
|
|
| |
Bongers V, deJong J, Steen I, De Vries N, Bast A, Snow GB, BraakhuisB.J.EurJ.CancerA(6):921-923(1995). |
|
|
| |
| A0920 |
N-Acetyl-S-(N'-phenethylthiocarbamoyl)-L-cysteine |
25 mg |
$75.30 |
| |
C14H18N2O3S2 FW 326.44 |
100mg |
$225.80 |
| |
Phenethyl isothiocyanate N-acteyl-L-cysteine conjugate; PEITC N-acetyl-L- |
500mg |
$878.10 |
| |
cysteine conjugate. |
|
|
| |
| A0819 |
Acetylsalicylic Acid / Aspirin |
500 g |
$50.40 |
| |
C9H8O4 FW 180.16 [50-78-2] |
1 kg |
$80.64 |
| |
Non-steroidal anti-inflammatory agent. Has undergone clinical |
|
|
| |
trials as a chemopreventive agent. |
|
|
| |
Kelloff GJ, Boone CW, Crowell JA et al. Cancer Epidemiol. Biomarkers Prev 3:85-98 (1994). |
|
|
| |
| A0825 |
Ac-GPK-pNA |
25 mg |
$761.60 |
| |
C21H30N6O6 FW 462.50 |
|
|
| |
| A0826 |
Ac-GPK(Ac)-pNA |
25 mg |
$761.60 |
| |
C23H32N6O7 FW 504.50 |
|
|
| |
| A0832 |
Ac-IEAR-pNA |
25 mg |
$761.60 |
| |
C28H43N9O9 FW 649.70 |
|
|
| |
| A0834 |
Ac-IETD-pNA |
25 mg |
$761.60 |
| |
C27H38N6O12 FW 638.6 |
|
|
| |
| A0833 |
Acipimox |
1 g |
$68.40 |
| |
C6H6N2O3 FW 154.12 [51037-30-0] |
5 g |
$265.80 |
| |
Acipimox inhibits lipolysis in peripheral tissues and induces large reduction in |
10 g |
$455.40 |
| |
circulating serum-free fatty acids. The mechanism of triglyceride lowering appears to |
|
|
| |
be an increase of VLDL-Tg clearance. |
|
|
| |
Nuutinen J, Minn H, Bergmand J et al. Br J. Cancer. 80:513-518 (1999). |
|
|
| |
Hannah JS, Bodkin NL, Paidi MS et al. Acta Diabetol. 32:279-283 (1995). |
|
|
| |
| A0934 |
Acivicin |
10 mg |
$134.40 |
| |
C5H7ClN2O3 FW 178.57 [42228-92-2] |
25 mg |
$302.40 |
| |
A specific inhibitor of g -glutamyl transpeptidase and transmembrane |
100 mg |
$963.20 |
| |
glutathione transport. Potent antitumor and antileishmania agent. Induces |
|
|
| |
apoptosis in human lymphoblastoid cells. |
|
|
| |
Griffith OW et al. Proc. Natl. Acad. Sci. USA 77:3384 (1980). |
|
|
| |
Earhart RH et al. Adv. Enzyme Regulation 24:179 (1986). |
|
|
| |
Mukherjee T et al. Biochem. Biophys. Res. Commun. 170:426 (1982). |
|
|
| |
Graber R, Losa GA. Int. J. Cancer. 62:443-8 (1995). |
|
|
| |
| A0958 |
Aconitine |
10 mg |
$30.50 |
| |
C34H47NO11 FW 645.74 [302-27-2] |
25 mg |
$53.20 |
| |
A diterpene alkaloid isolated from Aconiti Carmichaeli Praeparata used to |
100 mg |
$167.00 |
| |
induce cardiac arrhythmias. It binds to neurotoxin binding site 2 of the alpha- |
|
|
| |
sub-unit of the Na+ channel protein. |
|
|
| |
Telang BV, Ng'ang'a JN. Ind J Phy Pharm. 19:1-10 (1975). |
|
|
| |
Ameri A. Prog Neurobiol. 56:211-235 (1998). |
|
|
| |
| |
Acrinol (See Ethacridine lactate monohydrate) |
|
|
| |
| A0960 |
ACTH (1-39), human |
1 mg |
$761.60 |
| |
C207H308N56O58S FW 4541.1 [12279-41-3] |
|
|
| |
Adrenocorticotropic hormone. |
|
|
| |
| A0961 |
ACTH (1-39), rat |
0.5 mg |
$136.20 |
| |
C210H315N57O57S FW 4582.3 |
1 mg |
$231.20 |
| |
Adrenocorticotropic hormone. |
2.5 mg |
$408.60 |
| |
| A0962 |
ACTH (1-4) |
1 mg |
$21.50 |
| |
C20H30N4O8S FW 486.6 |
2 mg |
$35.80 |
| |
Adrenocorticotropic hormone. |
5 mg |
$64.50 |
| |
| A0963 |
ACTH (1-10), human |
1 mg |
$28.70 |
| |
C59H78N16O16S1 FW 1299.4 |
2 mg |
$48.40 |
| |
Adrenocorticotropic hormone. |
5 mg |
$86.00 |
| |
| A0964 |
ACTH (1-13), human |
0.5 mg |
$43.00 |
| |
C75H106N20O19S1 FW 1623.9 |
1 mg |
$73.50 |
| |
Adrenocorticotropic hormone. |
2.5 mg |
$129.00 |
| |
| A0965 |
ACTH (1-14) |
1 mg |
$43.00 |
| |
C77H169N21O20S1 FW 1680.9 |
2 mg |
$73.50 |
| |
Adrenocorticotropic hormone. |
5 mg |
$129.00 |
| |
| A0966 |
ACTH (1-16), human |
0.5 mg |
$50.20 |
| |
C89H133N25O22S FW 1937.27 |
1 mg |
$86.00 |
| |
Adrenocorticotropic hormone. |
2.5 mg |
$150.50 |
| |
| A0967 |
ACTH (1-17), human |
0.5 mg |
$50.20 |
| |
C95H145N29O23S FW 2093.5 |
1 mg |
$86.00 |
| |
Adrenocorticotropic hormone. |
2.5 mg |
$150.50 |
| |
| A0968 |
ACTH (1-24), human |
0.5 mg |
$50.20 |
| |
C136G210N40O31S FW 2933.5 |
1 mg |
$86.00 |
| |
Adrenocorticotropic hormone. |
2.5 mg |
$150.50 |
| |
| A0971 |
ACTH (4-10), human |
1 mg |
$35.80 |
| |
C44H59N13O10S1 FW 962.1 |
2 mg |
$60.90 |
| |
Adrenocorticotropic hormone. |
5 mg |
$107.50 |
| |
| A0970 |
ACTH (18-39), human |
1 mg |
$93.20 |
| |
C112H165N27O36 FW 2465.7 |
2 mg |
$157.70 |
| |
Adrenocorticotropic hormone. |
5 mg |
$279.60 |
| |
| A0977 |
Actinomycin D |
5 mg |
$82.00 |
| |
Dactinomycin |
10 mg |
$148.10 |
| |
C26H86N12O16 FW 1255.4 m.p. 241-243oC [50-76-0] |
|
|
| |
An antibiotic from Streptomyces. Has antineoplastic activity. |
|
|
| |
Hennings H, Boutwell RK. Life Sci., 6:173-181 (1967). |
|
|
| |
Harris CC. Cancer. 37 (2 Suppl):1014-1023 (1976). |
|
|
| |
| |
Actinomycin D, 7-Amino (See 7-Amino-Actinomycin) |
|
|
| |
| A0978 |
Actinonin |
5 mg |
$79.10 |
| |
C19H35N3O5 FW 385.50 [13434-13-4] |
|
|
| |
A naturally occurring antibacterial agent that is a potent peptide deformylase (PDF) inhibitor. |
|
|
| |
It has shown dose-dependent antitumor effects on AKR leukemia in vivo. |
|
|
| |
Xu Y, Lai LT, Gabrilove JL, et al. Clinical Cancer Research. 4:171-6 (1998). |
|
|
| |
Chen DZ, Patel DV, Hackbarth CJ et al. Biochemistry. 39:1256-62 (2000). |
|
|
| |
| A1084 |
Ac-VEID-pNA |
25 mg |
$761.60 |
| |
C28H40N6O11 FW 636.6 |
|
|
| |
| A1096 |
Acycloguanosine |
50 mg |
$61.30 |
| |
Acyclovir |
100mg |
$110.30 |
| |
C8H11N5O3 FW 225.20 m.p.256.5-257oC [59277-89-3] |
500mg |
$433.20 |
| |
An orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. |
|
|
| |
Elion GB et al. Proc Nat Acad Aci USA. 74:5716 (1977). |
|
|
| |
| |
Acyclovir (See Acycloguanosine A1096) |
|
|
| |
| A1097 |
Ac-YVAD-pNA |
25 mg |
$761.60 |
| |
C29H36N6O10 FW 628.6 |
|
|
| |
| A1202 |
Adapalene |
100mg |
$85.00 |
| |
C28H28O3 FW 412.52 [106685-40-9] |
250mg |
$150.00 |
| |
A moderator of cellular differentiation and inflammatory processes. Marketed |
1 g |
$380.00 |
| |
under the trade name Differin. A topical retinoid. |
|
|
| |
Horie, T. et. al. Jpn. Kokai Tokkyo Koho (2008), |
|
|
| |
Kawashima, M. J. Dermatological Science (2008), 49(3), 241-248. |
|
|
| |
Tenaud I. Experimental dermatology (2007), 16(6), 500-6 |
|
|
| |
| A1318 |
Adenine |
10 g |
$37.90 |
| |
C5H5N5 FW 135.13 [73-24-5] |
25 g |
$68.90 |
| |
Inhibits HL-60 cell growth by induction of apoptosis. Also induces |
|
|
| |
selective apoptosis toward MOLT4/HIV cells. |
|
|
| |
Tanaka Y, Yoshihara K, Tsuyuki M, Kamiya T. Exp. Cell Res. 213:242-52 (1994). |
|
|
| |
Hirasawa K, Yoshida O, Fujunami T et al. Biochem Biophys Res Commun. 273:1025-32 (2000). |
|
|
| |
| A1319 |
Adenosine Triphosphate Disodium |
1 g |
$27.70 |
| |
ATP |
5 g |
$66.30 |
| |
C10H16N5Na2O13P3 FW 551.14 [987-65-5] |
10 g |
$107.60 |
| |
A P2 purinergic agonist, it increases activity of Ca2+ activated K+ channels. |
25 g |
$237.40 |
| |
Arkhammar P, Hallberg A, Kindmark H et al. Biochem J. 265:203-11 (1990). |
|
|
| |
Jaffar ZH, Pearce FL. Agents Actions. 40:18-27 (1993). |
|
|
| |
| A1330 |
Adipokinetic Hormone |
1 mg |
$35.80 |
| |
C44H60N10O12 FW 921.0 |
2 mg |
$60.90 |
| |
Adipokinetic hormones are neurohormones that regulate the metabolism of |
5 mg |
$107.50 |
| |
carbohydrates and lipids during flight and locomotion. |
|
|
| |
Stone, J.V. Mordue, W. Batley, K.E., Morris, H.R. Nature 263:207-211 (1976). |
|
|
| |
Robinson, NL., Goldsworthy, G.J. J. Insect Physiol 23:9-16 (1977). |
|
|
| |
| A1331 |
Adipokinetic Hormone, AKH, locust |
1 mg |
$50.20 |
| |
C54H74N14O15 FW 1159.3 |
2 mg |
$86.00 |
| |
|
5 mg |
$150.50 |
| |
| A1332 |
Adipokinetic Hormone II from Locusta migratoria |
1 mg |
$50.20 |
| |
C43H58N11O11 FW 903.9 |
2 mg |
$86.00 |
| |
A grasshopper neuropeptide. |
5 mg |
$150.50 |
| |
Noves BE, Schaffer MH. DNA Cell Biol. 12(6):509-516 (1993). |
|
|
| |
| A1333 |
Adipokinetic Hormone II from Schistocera gregaria |
1 mg |
$50.20 |
| |
C44H60N11O12 FW 934.02 |
2 mg |
$86.00 |
| |
|
5 mg |
$150.50 |
| A1368 |
Adrenomedullin (1-52), human |
0.5 mg |
$451.60 |
| |
C264H406N80O77S3 FW 6028.9 |
1 mg |
$767.00 |
| |
A potent vasodilating peptide found in human pheochromocytoma from the |
2.5 mg |
$1,354.80 |
| |
adrenal medulla. Intravenous administration of adrenomedullin resulted in a |
|
|
| |
significant decrease in blood pressure along with total peripheral resistance. |
|
|
| |
Perret M. et. al. Life Sci. 53: 377-9 (1993). |
|
|
| |
Ishiyama Y. et. al. Eur J Pharmacol. 241:271-3 (1993). |
|
|
| |
| A1369 |
Adrenomedullin (13-52), human |
0.5 mg |
$358.40 |
| |
C200H308N58O59S2 FW 4533.17 |
1 mg |
$609.30 |
| |
|
2.5 mg |
$1,075.20 |
| |
| A1370 |
Adrenomedullin (22-52), human |
0.5 mg |
$215.00 |
| |
C159H252N46O48 FW 3576.06 |
1 mg |
$365.60 |
| |
|
2.5 mg |
$645.10 |
| |
| A1371 |
Adrenorphin |
1 mg |
$43.00 |
| |
C44H69N15O9S FW 984.2 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
Adriamycin (See doxorubicin HCl D5794) |
|
|
| |
| A1865 |
Aeroplysinin |
100 ug |
$95.20 |
| |
C9H9Br2NO3 FW 338.98 [28656-91-9] |
5x100 ug |
$425.60 |
| |
A naturally occurring tyrosine metabolite from the marine sponge |
1 mg |
$761.60 |
| |
Verongia aerophoba. It has been shown to interfere with key events in angiogenesis |
|
|
| |
and displays a strong anti-tumor effect on epidermal growth factor dependent tumor lines. |
|
|
| |
It has also been shown to have antileukemic acivity. |
|
|
| |
Rodriguez S, Gonzalez M, Carmona R, et al. FASEB Journal. 16:261-3 (2002). |
|
|
| |
Kreuter MH, Leake RE, Rinaldi F, et al. Comparative Biochem. 97:151-8 (1990). |
|
|
| |
Kreuter MH, Bernd A, Holzmann H, et al. Journal of Biosciences. 44:680-8 (1989). |
|
|
| |
| A2044 |
Aflatoxin B1 |
1 mg |
$28.00 |
| |
C17H12O6 FW 312.27 [1162-65-8] |
5 mg |
$112.00 |
| |
A potent hepatoxin and hepatocarcinogen oxidizes to form the carcinogenic, 2,3-exo-epoxide. |
|
|
| |
Chronic exposure produces necrosis, cirrhosis, and carcinoma of the liver. |
|
|
| |
Phillips, T., Tox. Sci. (52 Suppl), 118-126 (1999). |
|
|
| |
Daniels JM, Liu L, Stewart RK, Massey TE. Carcinogenesis. 5: 823-827 (1990). |
|
|
| |
| A2046 |
Aflatoxin B2 |
1 mg |
$76.20 |
| |
C17H14O6 FW 314.229 [7220-81-7] |
5 mg |
$369.60 |
| |
A potent hepatoxin and hepatocarcinogen found in poorly stored grains and nuts. |
|
|
| |
Chronic exposure is shown to produce mutagenesis, necrosis, and liver carcinogenesis. |
|
|
| |
Phillips, T., Tox. Sci. (52 Suppl), 118-126 (1999). |
|
|
| |
Daniels JM, Liu L, Stewart RK, Massey TE. Carcinogenesis. 5: 823-827 (1990). |
|
|
| |
| A2048 |
Aflatoxin G1 |
1 mg |
$78.40 |
| |
C17H12O7 FW 328.27 [1165-39-5 ] |
5 mg |
$380.80 |
| |
A mycotyxin produced by aspergillus parasiticus. |
|
|
| |
A toxic and carcinogenic mycotoxin that induces mutation of human chromosomes by forming |
|
|
| |
guanyl-N7 adducts in liver DNA. |
|
|
| |
el-Zawahri MM, Morad MM, Khishin AF. J Environ Pathol Toxicol Oncol. 10:45-51 (1990). |
|
|
| |
Baertschi SW, Raney KD, Shimada T, Harris TM, Guengerich FP. Chem Res Toxicol. 2:114-2 (1989). |
|
|
| |
| A2050 |
Aflatoxin G2 |
1 mg |
$188.20 |
| |
C17H14O7 FW 330.29 [7241-98-7] |
5 mg |
$604.80 |
| |
A mycotyxin produced by aspergillus parasiticus. Binds to DNAse II, exhibits inhibition effects. |
|
|
| |
Lotter LH, Schabort JC. Int J Biochem. 15:817-25 (1983). |
|
|
| |
| A2052 |
Aflatoxin M1 |
100 ug |
$60.50 |
| |
C17H12O7 FW 328.27 [6795-23-9] |
1 mg |
$353.90 |
| |
A potent hepatotoxic mycotyxin metabolite of Aflatoxin B1. Often found in milk of |
|
|
| |
cattle fed on AfB1 contaminated feed. Exhibits cytotoxic activities. |
|
|
| |
Neal G, Eaton D, Judah D, Verma A. Toxicol Appl Pharmacol. 151:1582-8 (1998). |
|
|
| |
| A2054 |
Aflatoxin M2 |
100 ug |
$152.30 |
| |
C17H14O7 FW 330.29 |
1 mg |
$1,070.70 |
| |
Metabolite of Aflatoxin B2, which is found in milk of cattle fed on AfB2. |
|
|
| |
Purchase, I, Food Cosmet Toxicol. 5:339-42 (1967). |
|
|
| |
| A2412 |
A-G-D-V |
5 mg |
$107.50 |
| |
C14H24N4O7 FW 360.37 |
10 mg |
$182.80 |
| |
|
25 mg |
$322.60 |
| |
| A4369 |
A-K-R-R-R-L-S-S-L-R-A |
1 mg |
$43.00 |
| |
C54H104N24O14 FW 1313.58 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
| A4401 |
A-L-A-L |
1 mg |
$14.30 |
| |
C18H34N4O5 FW 386.5 |
2 mg |
$25.10 |
| |
|
5 mg |
$43.00 |
| |
| A4400 |
Alamethicin |
1 mg |
$38.10 |
| |
C92H150N22O25 FW 1964.4 [27061-78-5] |
5 mg |
$154.60 |
| |
Alamethicin is a channel-forming ionophore. It activates membrane enzymes by |
|
|
| |
disrupting the membrane barriers of sarcolemmal vesicles, which gives substrates |
|
|
| |
and activators access to enzymatic sites in the interior of the vesicles. |
|
|
| |
Jones, L.R., Maddock, S.W., Besch , H.R. Jr. J. Biol. Chem. 255:9971-9980 (1980). |
|
|
| |
| A4402 |
L-Alaninol |
1 g |
$33.20 |
| |
S(+)-2-Amino-1-propanol |
10 g |
$227.70 |
| |
C3H9NO FW 75.11 [2749-11-3] m.p. 173-176oC [a]D=+18.0 |
|
|
| |
An amino acid alcohol with anti-proliferative effect. |
|
|
| |
Landau O, Wasserman L, Deutsch AA. Cancer Lett. 69:203-8 (1993). |
|
|
| |
| A4403 |
Alarelin Acetate |
Please inquire |
|
| |
C56H78N16O12 FW 1167.3 [79561-22-1] |
|
|
| |
A gonadotropin-releasing hormone analogue shown to inhibit DNA synthesis and poliferation of |
|
|
| |
rat gastric smooth muscle cells through GnRH receptors in vitro. |
|
|
| |
Chen L, He HX, Sun XD, Zhao J, Liu LH, Huang WQ, Zhang RQ. World J Gastroenterol. 10:1780-4 (2004). |
|
|
| |
| A4606 |
Albendazole |
10 g |
$51.10 |
| |
Methyl-5(propylthio)-2-benzimidazolecarbamate |
50 g |
$178.20 |
| |
C12H15N3O2S FW 265.33 m.p. 208-210oC [54965-21-8] |
|
|
| |
| |
Albendazole sulfoxide (See Ricobendazole R3310) |
|
|
| |
| A4508 |
Alclofenac |
5 g |
$40.20 |
| |
C11H11ClO3 FW 226.66 [22131-79-9] |
25 g |
$125.40 |
| |
A non-steroidal anti-inflammatory agent commonly used in the treatment of rheumatoid arthritis. |
100 g |
$376.30 |
| |
Brogden RN, Heel RC, Speight TM, et al. Drugs. 14:241-59 (1977). |
|
|
| |
Aylward M, Parker RJ, Holly F, et al. British Medical Journal. 2:7-9 (1975). |
|
|
| |
| A4515 |
Alendronate |
100mg |
$51.10 |
| |
C4H12NNaO7P2.3H2O FW 325.08 |
500mg |
$178.20 |
| |
A second generation bisphosphonate used as bone resorptive inhibitor. It induces apoptosis of rabbit |
|
|
| |
osteoclasts, human osteoclastoma-derived isteiclasts and human osteollclast-like cells |
|
|
| |
in vitro. The promotion of apoptosis of OCLs is related to the expression of FAS gene. |
|
|
| |
Woo T, Adachi JD. Baillieres Best Pract Res. Clin Rheumatol. 15:469-81 (2001). |
|
|
| |
Benford HL, McGowan NW, Helfrichg MH et al. Bone 28:465-73 (2001). |
|
|
| |
Wang XM, Yu SF, Yang ZP. Chin J Dent Res. 3:26-32 (2000). |
|
|
| |
| A4521 |
Alfacalcidol |
1 mg |
$100.40 |
| |
C27H44O2 FW 400.64 [41294-56-8] |
5 mg |
$407.70 |
| |
A bone resorption inhibitor. Has shown antitumor activity in non-Hodgkin's lymphomas. |
|
|
| |
Cunningham D, Gilchrist NL, Cowan RA et al. Brit Med J Clin Res. 291:1153-1155 (1985). |
|
|
| |
Shiraki M, Fukuchi M, Kiriyama T. J Bone Miner Metab. 22:352-359 (2004). |
|
|
| |
| A4438 |
Allatostatin I |
1mg |
$50.20 |
| |
C61H94N18O16 FW 1335.54 |
2 mg |
$86.00 |
| |
A neuropeptide that inhibits juvenile hormone synthesis in insects. Its inhibitory |
5 mg |
$150.50 |
| |
regulation of intestinal muscles, it was also found to modulate skeletal neuromuscular events. |
|
|
| |
Woodhead, AP., Stay, B, Seidel, SL, et al Proc. Natl. Acad. Sci.USA 86:5997-6001 (1989). |
|
|
| |
Kreissl, S. Weiss, T., Djokaj, S. Et al. Eur. J. Neurosci. 11:2519-2530 (1999). |
|
|
| |
| A4440 |
Allicin |
1 mg |
$163.30 |
| |
C6H10OS2 FW 162.27 [539-86-6] |
5 mg |
$573.80 |
| |
10 mg/ml methanol/water/formic acid (60:40:0.1) |
|
|
| |
The main biologically active compound in garlic. It exerts various biological effects, including |
|
|
| |
antiproliferative, chemopreventive, antioxidant, antihyperlipidaemic and antihypertensive effects. |
|
|
| |
It has been shown to inhibit the growth of cancer cells of murine and human origin in addition to |
|
|
| |
inhibiting telomerase activity and inducing apoptosis in gastric SGS-7901 cells. |
|
|
| |
Sela U, Ganor S, Hecht I et al. Immunology. 11:391-9 (2004). |
|
|
| |
Oommen S, Anto RJ, Srinivas G et al. Eur J Pharmacol. 485:97-103 (2004). |
|
|
| |
Sun L, Wang X. World J Gastroenterol. 9:1930-4 (2003). |
|
|
| |
| A4443 |
L(+) Alliin |
25 mg |
$155.30 |
| |
3-(2-Propenylsulfinyl) alanine |
50 mg |
$263.00 |
| |
C6H11NO3S FW 177.22 m.p. 163-1650C [a]D+60o |
100mg |
$477.60 |
| |
Optically pure form of alliin. |
|
|
| |
| A4444 |
L(+-) Alliin |
100mg |
$80.60 |
| |
3-(2-Propenylsulfinyl) alanine |
500mg |
$331.30 |
| |
C6H11NO3S FW 177.22 m.p. 163-165oC |
1 g |
$533.50 |
| |
Racemic mixture |
|
|
| |
| A4445 |
Allopurinol |
5 g |
$16.90 |
| |
4-Hydroxypyrazoleo [3,4-d]pyrimidine |
10 g |
$30.60 |
| |
C5H4N4O FW 136.11 m.p. >350oC [315-30-0] |
|
|
| |
An isomer of hypoxanthine. It is a potent xanthine oxidase inhibitor. |
|
|
| |
Kelley WN, Beardmore TD. Science, 169:388-390 (1970). |
|
|
| |
Marchmont RJ, Houslay MD. Biochem J. 195:653-660 (1981). |
|
|
| |
Weber G, Prajda N. Adv Enz Reg. 34:71-89 (1994). |
|
|
| |
| A4547 |
Alloxan Monohydrate |
5 g |
$16.50 |
| |
2,4,5,6(1H,3H)-pyrimidinetetrone monohydrate |
10 g |
$29.20 |
| |
C4H2N2O4 FW 142.07 |
25 g |
$55.10 |
| |
It is a cytotoxic compound which causes oxidative base damage to nuclear and mtDNA. |
|
|
| |
It also inhibits pancreatic cancer by selectively destroying pancreatic islet cells, |
|
|
| |
and gall bladder cancer. |
|
|
| |
Driggers WJ, Holmquist GP, LeDoux SP, Wilson GL. Nucleic Acids Res 25:4362-9 (1997). |
|
|
| |
Pour PM. Frontiers in Bioscience 2:271-282 (1997). |
|
|
| |
Pour PM, Donnelly K, Stepan K. Am J Pathology 110:310-4 (1983). |
|
|
| |
| |
S-Allyl-L-cysteine (See L-Deoxyalliin D1757) |
|
|
| |
| A4544 |
Allyl Disulfide |
500mg |
$70.40 |
| |
C6H10S2 FW 146.28 [2179-57-9] d 1.008 |
1 g |
$133.10 |
| |
Garlic constituent. Known to have anticarcinogenic and antimicrobial activity. |
5 g |
$594.20 |
| |
It inhibits human tumor cell proliferation, induces apoptosis in human colon tumor |
|
|
| |
cells, and selectively kills HIV-1-infected cells. |
|
|
| |
Reddy S, Rao CV, Rivenson A, Kelloff G. Cancer Res. 35:3493-8 (1993). |
|
|
| |
Sundaran SG, Milner JA. Biochim Biophys Acta. 1315:15-20 (1996). |
|
|
| |
Sundaran SG, Milner JA. Carcinogenesis. 17:669-73 (1996). |
|
|
| |
Shoji S, Furuishi K, Yanase R et al. Biochem Biophys Res Commun. 194:610-21 (1993). |
|
|
| |
| A4577 |
Alsterpaullone |
1 mg |
$110.70 |
| |
C16H11N3O3 FW 293.28 |
5 mg |
$498.00 |
| |
The most active paullone. It is a potent inhibitor of glycogen synthase kinase-3b and cyclin- |
|
|
| |
dependent kinase 5/p25. It has been shown to induce apoptosis and promote loss in clonogenicity |
|
|
| |
in the Jurkate cell line. |
|
|
| |
Leost M, Schultz C, Link A et al. European J Biochem. 267:5983-94 (2000). |
|
|
| |
Lahusen T, De Siervi A, Kunick C et al. Molecular Carcinogenesis. 36:183-94 (2003). |
|
|
| |
| A4578 |
Altretamine |
500mg |
$55.20 |
| |
C9H18N6 FW 210.28 [645-05-6] |
1 g |
$82.90 |
| |
An antineoplastic agent. Active in ovarian cancer, lymphomas, bronchogenic |
5 g |
$338.10 |
| |
carcinoma, and carcinoma of the breast. |
|
|
| |
Lake LM, Grunden EE, Johnson BM. Cancer Res. 35:2858-63 (1975). |
|
|
| |
Legha SS, Slavik M, Carter SK. Cancer. 38:27-35 (1976). |
|
|
| |
| A4496 |
Alyssin, 97% |
25 mg |
$104.30 |
| |
C7H13NOS2 FW 191.32 [646-23-1} |
50 mg |
$181.00 |
| |
Homolog of sulforaphane. |
100mg |
$325.80 |
| |
|
500mg |
$1,094.70 |
| |
| A4497 |
Alyssin sulfone, 97% |
25 mg |
$96.10 |
| |
C7H13NO2S2 FW 207.31 |
50 mg |
$160.30 |
| |
|
100 mg |
$288.30 |
| |
|
500 mg |
$971.40 |
| |
| A4498 |
Alytesin |
1 mg |
$35.80 |
| |
C68H106N22O17S FW 1535.8 |
2 mg |
$60.90 |
| |
A neuropeptide isolated from amphibian skin that stimulates gastric acid |
5 mg |
$107.50 |
| |
secretion, intestinal contraction and hypertension in dogs. |
|
|
| |
Anastasi et. al. Experientia. 27:166-7 (1971). |
|
|
| |
| A4802 |
Amantadine Hydrochloride |
25 g |
$58.00 |
| |
Adamantan-1-amine |
100 g |
$186.40 |
| |
C10H17N.HCl FW 187.71 [66.66-7} |
|
|
| |
An antiviral drug. Inhibits ion channels of influenza, and disrupts T-cell development. |
|
|
| |
Griffin SD, Beales LP, Clarke DS et al. FEBS Lett. 535:34-8 (2003). |
|
|
| |
Smith CA, Graham CM, Mathers K et al. Immunology. 105:306-13 (2002). |
|
|
| |
| A4803 |
Amantadine Sulfate |
25 g |
$58.00 |
| |
(C10H17N)2.H2SO4 FW 400.58 |
100 g |
$186.40 |
| |
| A4805 |
Amastatin Hydrochloride |
1 mg |
$100.40 |
| |
C21H38N4O8.HCl FW 511.1 [200938-10-1] |
5 mg |
$332.40 |
| |
An inhibitor of aminopeptidase shown to prolong the effect of both vasopressin |
10 mg |
$602.10 |
| |
and oxytocin. |
|
|
| |
Meisenberg G, Simmons WH. Peptides. 5:535-9 (1984). |
|
|
| |
Chen X, Pittman QJ. J Neurophysiol. 82:1689-96 (1999). |
|
|
| |
| |
L-(+)-Amethopterin Dihydrate (See Methotrexate) |
|
|
| |
| A4806 |
Ambroxol Hydrochloride |
1 g |
$31.40 |
| |
C13H18Br2N2O.HCl FW 414.57 [23828-92-4] |
5 g |
$56.40 |
| |
A metabolite of bromhexine that is a mucolytic agent. It prevents neutrophil- |
25 g |
$188.20 |
| |
mediated A1AT inactivation via inhibition of HOCl production as well as HOCl |
|
|
| |
scavenging, in addition to inhibiting proinflammatory cytokines. |
|
|
| |
Su X, Wang L, Song Y et al. Intens Care Med. 30:133-40 (2004). |
|
|
| |
Ottonello L, Arduino N, Bertolotto M et al. Brit J Pharmacol. 140:736-42 (2003). |
|
|
| |
Sepulveda J, Velasquez BJ. Respiration. 43:363-88 (1982). |
|
|
| |
| A4933 |
Amifostine |
50 mg |
$73.90 |
| |
Aminopropyl aminoethylthiophosphate |
100mg |
$131.20 |
| |
C5H15N2O3PS FW 214.22 [20537-88-6] |
500mg |
$491.80 |
| |
Amifostine is a chemoprotective drug used to selectively protect normal tissues from the |
|
|
| |
of chemotherapeutic drugs such as cyclophosphamide, mitomycin-C and cisplatin, |
|
|
| |
and ionizing radiation therapy. |
|
|
| |
Culy CR, Spencer CM. Drugs 61:641-84 (2001). |
|
|
| |
Grdina DJ, Kataoka Y, Murley JS. Drug Metabol Drug Interact 16:237-79 (2000). |
|
|
| |
| A5132 |
Amikacin Disulfate |
250mg |
$33.20 |
| |
C22H43N5O13.2H2SO4 FW 781.76 [39831-55-5] |
1 g |
$82.90 |
| |
An aminoglycoside antibiotic derived from Kanamycin A. |
5 g |
$276.00 |
| |
Danhauer FJ, Fortner CL, Schimpff SC et al. Clin Pharm. 1:539-43 (1982). |
|
|
| |
Guy H, Chavanet P, Portier H, et al. Nouv Presse Med. 10:654-6 (1981). |
|
|
| |
| A5133 |
Amiloride HCl |
500mg |
$27.70 |
| |
C6H8ClN7O.HCl.2H2O FW 302.12 [17440-83-4] |
1 g |
$37.30 |
| |
Potassium-sparing diuretic. |
5 g |
$135.30 |
| |
Baer JE, Jones CB, Spitzer SA, Russo HF. J Pharmacol Exp Ther 157:472-85 (1967). |
|
|
| |
| A4930 |
7-Amino-actinomycin D |
1 mg |
$80.60 |
| |
C62H87N13O16 FW 1270.430 [7240-37-1] |
5 mg |
$403.20 |
| |
A reagent used as a cytochemical probe. It forms complexes with DNA in solution resulting in shifts |
|
|
| |
of both the excitation and emission wavelengths. It has been used successfully to identify apoptosis. |
|
|
| |
Gill, J.E.; Jotz, M.M.; Young, S.G et al. J Histochem & Cytochem. 23:793-799 (1975). |
|
|
| |
Philpott, N.J., Turner, A.J., Scopes, J. et al. Blood 87:2244-2241 (1996). |
|
|
| |
| A4931 |
3-Aminobenzamide |
100mg |
$49.70 |
| |
C7H8N2O FW 136.15 |
250mg |
$96.30 |
| |
A poly (ADP-ribose) Polymerase (PARP) inhibitor. A stress response protein |
500mg |
$259.60 |
| |
activated by cytotoxic agents and makes cells resistant to apoptosis. It inhibits the |
|
|
| |
modification of specific sites in replicating DNA. It also stimulates repair replication |
|
|
| |
after exposure to alkylating agents. |
|
|
| |
Lee YJ, Shacter E. J Biol Chem. 274:19792-8 (1999). |
|
|
| |
Kurian P, Kumari HL, Milo GE. Carcinogenesis. 13:489-91 (1992). |
|
|
| |
Cleaver JE. Carcinogenesis. 17:1-3 (1996). |
|
|
| |
| |
g-Amino-n-butyric acid (See GABA G0048) |
|
|
| |
| A4935 |
6-Aminocaproic acid |
10 g |
$20.20 |
| |
C6H13NO2 FW 131.17 [60-32-2] |
100 g |
$34.70 |
| |
A protease inhibitor with chemopreventive properties. It inhibits chemically induced carcinogenesis |
|
|
| |
of the esophagus, peripheral nerve, brain and kidney in experimental animals. |
|
|
| |
Bespalov VG, Aleksandrov VA, Petrov AS, Troian DN. Vopr Onkol. 38(1):69-74. (1992). |
|
|
| |
Alexandrov VA, Bespalov VG, Petrov AS, Troyan DN, Lidaks MYu. Carcinogenesis. 17(9):1935-9 (1996). |
|
|
| |
| A5032 |
DL-Aminoglutethimide |
500mg |
$51.60 |
| |
3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione |
1g |
$86.10 |
| |
C13H16N2O2 FW 232.28 [125-84-8] |
|
|
| |
An adrenocortical suppressant which also inhibits conversion of androgens to estrogens by the |
|
|
| |
aromatase enzyme system. Reduces tumor multiplicity and increases latent period of |
|
|
| |
MNU-induced mammary tumorigenesis. |
|
|
| |
Pelissero C, Lenczowski MJ, Chinzi D et al. J Steroid Biochem Mol Biol. 57:215-23 (1996). |
|
|
| |
Moon RC, Steele VE, Kelloff GJ et al. Anticancer Res. 14:889-93 (1994). |
|
|
| |
| A4940 |
6-Aminonicotinamide |
1 g |
$109.80 |
| |
C6H7N3O FW 137.14 [329-89-5] |
5 g |
$448.00 |
| |
Induces apoptosis in tumor cells. Member of the drug combination called PMA which induces |
|
|
| |
regression of murine mammary tumors by depleting ATP. |
|
|
| |
Ogata S, Takeuchi M, Fujit, H et al. Biosci Biotechnol Biochem 64:327-332 (2000). |
|
|
| |
Nord, L.D., Stolfi, R.L., Alfieri, A.A., et al Cancer Chemother Pharmacol. 40:376-384 (1997). |
|
|
| |
Colofiore JR, Stolfi RL, Nord LD, Maartin DS. Biochem Pharmacol 50:1943-8 (1995). |
|
|
| |
| A5001 |
Aminopterin |
25 mg |
$85.30 |
| |
4-Aminofolic acid |
100mg |
$263.40 |
| |
C19H20N8O5 FW 440.41 [54-62-6] |
500mg |
$896.90 |
| |
An inhibitor of dihydrofolate reductase shown to induce apoptosis in mouse |
|
|
| |
HGPRT(-) myeloma cell lines. |
|
|
| |
Chung YH, Youn J, Choi Y et al. Immunol Lett. 77:127-31 (2001). |
|
|
| |
Kremer P, Hartung G, Bauder-Wust U et al. Anticancer Drugs. 13:615-23 (2002). |
|
|
| |
| A5030 |
4-Aminophenylphosphate monosodium salt, 98% |
10 mg |
$48.00 |
| |
C6H7NO4PNa FW 211.09 [52331-30-3] |
50 mg |
$163.40 |
| |
Substrate for the electrochemical measurement of alkaline phosphatase. |
100mg |
$293.90 |
| |
Frew JE, Foulds NC, Wilshere JM, Forrow NJ, Green MJ. J. Electroanal. Chem., 266:309-316 (1989). |
|
|
| |
| A5134 |
Aminophylline Anhydrous |
25 g |
$48.40 |
| |
C16H24N10O4 FW 420.43 [317-34-0] |
100 g |
$69.00 |
| |
The water soluble complex of Theophyline. A non-selective phosphodiesterase |
500 g |
$207.00 |
| |
inhibitor. |
|
|
| |
Noguchi Y, Ito M, Katsumi K et al. Gastroenterol Jpn. 21:129-34 (1986). |
|
|
| |
Reddy SV, Maderdrut JL, Yaksh TL. J Pharmacol Exp Ther. 213:525-33 (1980). |
|
|
| |
| A5135 |
Aminophylline Dihydrate |
25 g |
$38.60 |
| |
C16H24N10O4.2H2O FW 456.47 |
100 g |
$48.40 |
| |
|
500 g |
$117.40 |
| |
| A5033 |
4-Aminosalicylic acid |
25 g |
$13.90 |
| |
p-Aminosalicylic acid |
100 g |
$24.90 |
| |
C7H7NO3 FW 153.14 [65-49-6] |
500 g |
$110.40 |
| |
An antituberculous agent. Effective in treatment of distal ulcerative colits. |
|
|
| |
Oda N, Matsumoto K. Yakushigaku Zasshi 36:161-6 (2001). |
|
|
| |
O'Donnell LJ, Arvind AS, Hoang P et al. Gut. 33:947-9 (1992). |
|
|
| |
| A5034 |
4-Aminosalicylic acid sodium dihydrate |
25 g |
$13.90 |
| |
p-Aminosalicylic acid sodium salt |
100 g |
$22.20 |
| |
C7H6NNaO3.2H2O FW 211.15 [6018-19-5] |
500 g |
$103.50 |
| |
Sodium salt of p-Aminosalicylic acid. |
|
|
| |
| A5035 |
5-Aminosalicylic acid |
25 g |
$69.00 |
| |
Mesalazine; mesalamine |
100 g |
$179.40 |
| |
C7H7NO3 FW 153.14 [89-57-6] |
|
|
| |
The active metabolite of Sulphasalazine. Effective in remission of Crohn's disease. |
|
|
| |
Rhodes JM, Bartholomew TC, Jewell DP. Glut. 22:642-7 (1981) |
|
|
| |
Modigliani R, Colombel JF, Dupas JL et al. Gastroenterology 110:688-93 (1996). |
|
|
| |
| A5037 |
Amiodarone Hydrochloride |
1 g |
$34.50 |
| |
C25H29I2NO3.HCl FW 681.78 [19774-82-4] |
5 g |
$117.40 |
| |
Benzofuran derivative with multiple electrophysiological effects. |
10 g |
$193.20 |
| |
Induces apoptosis in human and rat alveolar epithelial cells in vitro. |
|
|
| |
Bargout R, Jankov A, Dincer E et al. Am J Physiol Lung Cell Mol Physiol. 27:1039-44 (2000). |
|
|
| |
Abdul M, Hoosein N. Cancer Lett. 186:99-105 (2002). |
|
|
| |
| A5234 |
Amisulpride |
25 mg |
$56.00 |
| |
C17H27N3O4S FW 681.78 [71675-85-9] |
100mg |
$179.20 |
| |
Enhances dopaminergic neurotransmission by preferentially blocking D2/D3 |
500mg |
$504.00 |
| |
autoreceptors. A second generation antipsychotic. |
|
|
| |
Rettenbacher M. Journal of psychopharmacology (2007), 21(4), 400-4. |
|
|
| |
Strasser O. Psychiatrische Praxis (2004), 31 Suppl 1 S38-40. |
|
|
| |
Curran M P Drugs (2001), 61(14), 2123-50. |
|
|
| |
| A5039 |
Amitraz |
5 g |
$41.40 |
| |
C19H23N3 FW 293.41 33089-61-1] |
25 g |
$110.40 |
| |
Formamidine pesticide with carcinogenic potential. It has been shown that |
100 g |
$345.00 |
| |
amitraz-induced mydriasis is mediated by postsynaptic alpha 2-adrenoreceptors while |
|
|
| |
amitraz-induced bradycardia is mediated by presynaptic alpha 2-adrenoreceptors. |
|
|
| |
Moser VC, MacPhail RC. Toxicol Lett. 28:99-104 (1985). |
|
|
| |
Hsu WH, Kakuk TJ. Toxicol Appl Pharmacol 73:411-5 (1984). |
|
|
| |
| A5235 |
Amitriptyline Hydrochloride |
10 g |
$25.20 |
| |
C20H23N.HCl FW 277.4 [549-18-8] |
25 g |
$50.40 |
| |
A tricyclic anti-depressant. Inhibits uptake of serotonin and noradrenaline |
100 g |
$145.60 |
| |
equally. |
|
|
| |
Altintoprak, A. Human Psychopharmacology (2008), 23(4), 313-319 |
|
|
| |
Sawynok, J. Neuroscience Letters (2008), 440(2), 181-184. |
|
|
| |
| A5045 |
Amlodipine |
1 g |
$41.40 |
| |
C20H25ClN2O5 FW 408.88 [88150-42-9] |
5 g |
$158.70 |
| |
A calcium channel antagonist with potent antioxidant activity. It inhibits |
10 g |
$207.00 |
| |
doxorubicin-induced myocyte apoptosis by supressing the mitochondrial apoptotic |
|
|
| |
pathway. It has been found to inhibit hyperplasia and hypertrophy in mesangial cells. |
|
|
| |
Yamanka S, Tatsumi T, Shiraishi J et al. J Am Coll Cardiol. 41:870-8 (2003). |
|
|
| |
Shultz PJ, Raij L. Am J Hypertens. 5:912-4 (1992). |
|
|
| |
| A5044 |
Amlodipine besylate |
1 g |
$44.20 |
| |
C20H25ClN2O5.C6H5SO3H FW 567.06 [111470-99-6] |
5 g |
$162.80 |
| |
A calcium channel blocker commonly used in the treatment of hypertension and |
10 g |
$218.10 |
| |
angina. It also has shown antireproductive effects in male rats: a reduction in sperm |
|
|
| |
density, the amount of mature spermatids, and the number of Sertoli cells. |
|
|
| |
Almeida SA, Teofilo JM, Anselmo JA et al. Exp Toxicol Pathol. 52:353-6 (2000). |
|
|
| |
| A5056 |
Amorolfine Hydrochloride |
100mg |
$44.80 |
| |
C21H35NO.HCl FW 353.97 |
250mg |
$84.00 |
| |
A morpholine antimycotic agent. Interferes with ergosterol biosynthesis. |
1 g |
$179.20 |
| |
Hiratani, T. Asaqu Y. Matsusaka, A et al. Jpn. J. Antibiot. 44:993-1006 (1991). |
|
|
| |
Polak A. Dermatology 184Suppl1:3-7 (1992). |
|
|
| |
| A5059 |
Amoxapine |
250mg |
$50.40 |
| |
C17H16ClN3O FW 313.78 [14028-44-5] |
1 g |
$140.00 |
| |
Tricyclic antidepressant. In animals it inhibits the reuptake of norepinephrine |
5 g |
$425.60 |
| |
and to a lesser degree serotonin. |
|
|
| |
Chaudhry, I. J. of Clinical Psychopharmacology (2007), 27(6), 575-581. |
|
|
| |
Keck, T. J. Neuroscience (2008), 28(29), 7359-7369. |
|
|
| |
| A5057 |
Amoxicillin |
5 g |
$31.40 |
| |
C16H19N3O5S FW 365.41 [26787-78-0] |
25 g |
$56.40 |
| |
A semi-synthetic antibiotic similar to penicillin. |
100 g |
$169.30 |
| |
Kochi T, Tachimori Y, Itoh N et al. Jpn J Antibiot. 34:1395-400 (1981). |
|
|
| |
Brogeden RN, Speight TM, Avery GS. Drugs. 9:88-140 (1975). |
|
|
| |
| A5130 |
Amphotericin B |
100mg |
$43.90 |
| |
C47H73NO17 FW 924.08 [1397-89-3] |
250mg |
$72.80 |
| |
A polyene antibiotic produced by Streptomycetes nodosus that has shown |
500mg |
$125.40 |
| |
antitumor activity. |
1 g |
$188.20 |
| |
Presant CA, Metter GE, Multhauf P et al. Cancer Treat Rep. 68:651-4 (1984). |
|
|
| |
Medoff J, Medoff G, Goldstein MN et al. Cancer Res. 35:2548-52 (1975). |
|
|
| |
| A5160 |
Ampicillin Trihydrate |
5 g |
$31.10 |
| |
C16H19N3O4S.3H2O FW 403.47 [7177-48-2] |
25 g |
$75.90 |
| |
An antibiotic. Semi-synthetic penicillin. |
100 g |
$207.00 |
| |
Visuri T, Antila P, Laurent LE. Ann Chir Gynaecol Suppl. 65:58-61 (1976). |
|
|
| |
| A5161 |
Ampiroxicam |
1 g |
$34.50 |
| |
C20H21N3O7S FW 447.46 [99464-64-9] |
5 g |
$89.70 |
| |
A prodrug of piroxicam with reduced gastrointestinal irritation. It is a non- |
25 g |
$365.70 |
| |
steroidal anti-inflammatory agent proven to be an effective chemopreventive agent. |
|
|
| |
Olkkola KT, Brunetto AV, Mattila MJ. Clin Pharmacokinet. 26:107-20 (1994). |
|
|
| |
Carty TJ, Marfat A, Moore PF et al. Agents Actions. 39:157-65 (1993). |
|
|
| |
| A5162 |
Amprolium Hydrochloride |
25 g |
$30.50 |
| |
C14H19ClN4.HCl FW 315.25 [137-88-2] |
100 g |
$103.30 |
| |
A coccidiostat mainly used in poultry feed. It inhibits the sporulation of the oocysts |
|
|
| |
of several common strains of coccidia. |
|
|
| |
Joyner, LP., Norton, CC. Parasitology 75:155-164 (1977). |
|
|
| |
| A5170 |
Amrinone |
250mg |
$41.40 |
| |
C10H9N3O FW 187.20 [6071984-8] |
1 g |
$110.40 |
| |
Selective phosphodiesterase III inhibitor. A nonglycoside, noncatecholamine agent |
|
|
| |
with positive inotropic effect. Inhibits cyclic AMP-dependent protein kinase activity |
|
|
| |
by competing with ATP but not cyclic AMP binding sites. It also inhibits platelet |
|
|
| |
aggregation and induces disaggregation. |
|
|
| |
Ono S, Ueda S, Sakuma T et al. J Cardiov. Surgery 37:177-81 (1996). |
|
|
| |
Earl CQ, Linden J, Weglicki WB. Life Sciences 39:1901-8 (1986). |
|
|
| |
Kikura M, Kazama T, Ikeda T et al. Platelets 11:446-58 (2000). |
|
|
| |
| A5193 |
Amygdalin |
1 g |
$25.10 |
| |
C20H27NO11 FW 457.43 [29883-15-6] |
5 g |
$37.60 |
| |
A benzylic glycoside that has been used as an antineoplastic agent. |
25 g |
$150.50 |
| |
Fukuda T, Ito H, Makainaka et al. Biol Pharm Bull. 26:271-273 (2003). |
|
|
| |
Stock CC, Martin DS, Sugiura K et al. J Surgical Oncology. 10:89-123 (1978). |
|
|
| |
| A4844 |
Amylin (8-37), human |
0.5 mg |
$193.50 |
| |
C138H215N41O46 FW 3184.5 |
1 mg |
$329.70 |
| |
Putative polypeptide hormone from type 2 human diabetes and adult diabetic |
2.5 mg |
$580.60 |
| |
cats which consists of 37-amino acid peptide subunit of amyloid. |
|
|
| |
Edwards, B. J.; Morley, J. E. Life Sci. 51:1899-1912 (1992). |
|
|
| |
| A4845 |
Amylin (8-37), rat |
0.5 mg |
$193.50 |
| |
C140H227N43O43 FW 3200.63 |
1 mg |
$329.70 |
| |
|
2.5 mg |
$580.60 |
| |
| A4846 |
Amylin (IAPP)(Feline) |
0.5 mg |
$207.90 |
| |
C165H270N52O54S2 FW 3910.45 |
1 mg |
$353.00 |
| |
|
2.5 mg |
$623.60 |
| |
| |
| A4847 |
Amylin, human |
0.5 mg |
$115.50 |
| |
C165H261N51O55S2 FW 3903.4 |
1 mg |
$195.80 |
| |
A member of the calcitonin family of hormones that is co-secreted with insulin |
2.5 mg |
$346.30 |
| |
from the pancreas during and after food intake. It inhibits RINm5F islet beta-cell |
|
|
| |
proliferation and evokes apoptosis associated with typical degenerative ultrastructural |
|
|
| |
changes and DNA fragmentation. |
|
|
| |
Zhang S, Liu J, Saafi EL et al. FEBS Lett. 455:315-20 (1999). |
|
|
| |
Riediger T, Zuend D, Becskei C et al. Am J Physiol Regul Integr Comp Physiol. 286:R114-22 (2004). |
|
|
| |
| A4850 |
Amylin, rat |
0.5 mg |
$164.90 |
| |
C167H270N52O53S2 FW 3918.47 |
1 mg |
$279.60 |
| |
|
2.5 mg |
$494.60 |
| |
| A4851 |
b-Amyloid (1-40), rat |
0.5 mg |
$236.50 |
| |
C190H291N51O57S1 FW4233.81 [131438-79-4] |
1 mg |
$401.40 |
| |
A protein that stimulates the release of nitric oxide in neuronal cell lines. It often |
2.5 mg |
$709.60 |
| |
forms the neurotoxic peptide deposits associated with Alzheimer's disease and aging. |
|
|
| |
Hu J, el-Fakahany EE. Neuroreport. 4(6):760-762 (1993). |
|
|
| |
| A4852 |
b-Amyloid (1-40), Ultra Pure, TFA |
0.5 mg |
$236.50 |
| |
C194H295N53O58S1 FW4329.9 |
1 mg |
$401.40 |
| |
|
2.5 mg |
$709.60 |
| |
| A4853 |
b-Amyloid (1-42), human |
0.5 mg |
$236.50 |
| |
C203H311N55O60S1 FW 4514.14 |
1 mg |
$401.40 |
| |
|
2.5 mg |
$709.60 |
| |
| A4849 |
b-Amyloid (25-35) |
1 mg |
$31.10 |
| |
C45H81N13O14S1 FW 1060.3 [131602-53-4] |
2 mg |
$75.90 |
| |
The 11-residue functional domain of Amyloid-b protein. |
5 mg |
$207.00 |
| |
| A4854 |
b-Amyloid Peptide (1-42), rat |
1 mg |
$265.20 |
| |
C199H307N53O59S1 FW 4454.09 [107761-42-2] |
2 mg |
$451.60 |
| |
|
5 mg |
$795.60 |
| |
| A4848 |
Amyloid-b Protein (1-40) |
1 mg |
$361.30 |
| |
C194H295N53O58S Mol Wt: 4329.8 |
|
|
| |
A protein that stimulates the release of nitric oxide in neuronal cell lines. It often forms the |
|
|
| |
neurotoxic peptide deposits associated with Alzheimer's disease and aging. |
|
|
| |
Hu J, el-Fakahany EE. Neuroreport. 4(6):760-762 (1993). |
|
|
| |
| A5202 |
Anabasine Hydrochloride |
25 mg |
$27.70 |
| |
C10H14N2.HCl FW 198.73 [15251-47-5] |
100mg |
$71.80 |
| |
An anabisis aphylla alkaloid with antialcoholic effects. It has been shown to |
|
|
| |
suppress breast cancer aromatase activity. |
|
|
| |
Kadohama N, Shintani K, Osawa Y. Cancer Lett. 75:175-82 (1993). |
|
|
| |
Mirzaez S. Farmakol Toksikol. 41:52-5 (1978). |
|
|
| |
| A5302 |
Anastrozole |
100mg |
$76.20 |
| |
C17H19N5 FW 293.37 [120511-73-1] |
250mg |
$140.00 |
| |
A selective aromatase inhitor used to treat hormone-responsive metastic |
1 g |
$425.60 |
| |
breast cancer. It may be effective against recurrent ovarian adult granluosa cell tumors. |
|
|
| |
Plourde, PV., Dyroff, M., Dowsett, M. et al. J. Steroid Biochem. Mol. Biol 53:175-179 (1995). |
|
|
| |
Freeman, SA., Modesitt, SC. Gynecol Oncol. 103:755-758 (2006). |
|
|
| |
| A5313 |
Andrographolide |
1 mg |
$68.90 |
| |
C20H30O5 FW 350.45 [5508-58-7] m.p. 228-2300C (dec.) |
5 mg |
$249.80 |
| |
Andrographolide is from Andrographis paniculata. It inhibits PAP-induced |
10 mg |
$364.80 |
| |
human blood platelet aggregation, inhibits nitrite synthesis in macrophage, |
|
|
| |
and restores vasocontractile response in thoracic aorta. |
|
|
| |
Amroyan E, Gabrielian E, Panossian A et al. Phytomedicine 6:27-31 (1999). |
|
|
| |
Chiou WF, Lin JJ, Chen CF. Br. J. Pharmacol. 125:327-334 (1998). |
|
|
| |
| A5314 |
Andrographolide, dehydro- |
1 mg |
$68.90 |
| |
C20H28O4 FW 332.43 |
5 mg |
$249.80 |
| |
|
10 mg |
$364.80 |
| |
| A5315 |
Andrographolide, deoxy- |
1 mg |
$68.90 |
| |
C20H30O4 FW 334.45 |
5 mg |
$249.80 |
| |
Anti-inflammatory drug isolated from Andrographis paniculata Nees. A potent |
10 mg |
$364.80 |
| |
cell differentiation-inducer of M1 cells. |
|
|
| |
Shen YC, Chen CF, Chiou WF. Planta Med. 66:314-7 (2000). |
|
|
| |
Matsuda T, Kuroyanagi M, Sugiyama S et al. Chem Pharm Bull 42:1216-25 (1994). |
|
|
| |
| A5217 |
trans-Anethole |
50 ml |
$52.60 |
| |
p-Propenylanisole |
100 ml |
$90.80 |
| |
C10H12O FW 148.20 m.p. 230C [4180-23-8] |
|
|
| |
Induces Phase II drug-metabolizing enzymes. A potential |
|
|
| |
anti-carcinogen in Ehrlich ascites tumor cells. |
|
|
| |
Rompelberg CJ, Verhagen H, van Bladeren PJ. Food Chem Toxicol., 31:637-645 (1993). |
|
|
| |
al-Harbi MM, Qureshi S, Raza M et al. Eur J Cancer Res. 4:307-318 (1995). |
|
|
| |
| A5219 |
Anethole-trithione |
25 mg |
$62.20 |
| |
C10H8OS3 FW 240.37 [532-11-6] |
100mg |
$200.10 |
| |
Analogue of the chemopreventive agent oltipraz. It was shown to increase |
500mg |
$689.90 |
| |
cholinergic and adrenergic responsiveness in rats. Mechanism may act by |
|
|
| |
stimulating some post-receptor effect in the coupling to the secretory response. |
|
|
| |
Lubet RA, Steele VE, Eto I et al. Int J Cancer. 72:95-101 (1997). |
|
|
| |
Glenert U. Eur J Pharmacol. 226:43-52 (1992). |
|
|
| |
| A5225 |
a-ANF(1-28), human |
0.5 mg |
$193.50 |
| |
C127H203N45O39S3 FW 3080.46 [91917-63-4] |
1 mg |
$329.70 |
| |
The major form of atrial natriuretic peptide in circulation throughout the body. |
2.5 mg |
$580.60 |
| |
Modulates saline and fluid balance in the blood by stimulating renin release. |
|
|
| |
Hisa H, Tomura Y, Satoh S. Am J Physiol. 257(3 Pt 1):E332-335 (1989). |
|
|
| |
| A5228 |
Angiogenin |
50 ug |
$1,256.50 |
| |
Mol. Wt. ~14,000 Da |
|
|
| |
An endogenous single chain protein that induces the formation of blood vessels. |
|
|
| |
Fett JW. Biochemistry 24:5480 (1985). |
|
|
| |
Shapiro R. Biochemistry 26:5141 (1987). |
|
|
| |
| A5230 |
Angiostatin |
0.5 mg |
$711.30 |
| |
A 38-kD fragment of plasminogen that is a potent endothelial cell growth inhibitor. |
|
|
| |
It has been shown to inhibit angiogenesis in vivo and tumor growth in mice. |
|
|
| |
O'Reilly MS, Holmgren L, Chen C et al. Cell. 79:315-28 (1994). |
|
|
| |
Scappaticci FA, Smith R, Pathak A et al. Molecular Therapy. 3:186-96 (2001). |
|
|
| |
| A5070 |
Angiotensin Acetate |
Please inquire |
|
| |
C49H69N13O12 FW 1032.18 |
|
|
| |
| |
| A5272 |
Angiotensin, Canine, rat |
5 mg |
$50.20 |
| |
C41H62N12O11 FW 899.03 |
10 mg |
$86.00 |
| |
|
25 mg |
$150.50 |
| |
| A5273 |
Angiotensin Converting Enzyme Inhibitor |
5 mg |
$28.70 |
| |
C53H77N14O12 FW 1102.29 |
10 mg |
$48.40 |
| |
|
25 mg |
$86.00 |
| |
| A5275 |
Angiotensin I [Des-Asp1-], human |
5 mg |
$21.50 |
| |
C58H84N16O11 FW 1181.42 |
10 mg |
$35.80 |
| |
|
25 mg |
$64.50 |
| |
| A5276 |
Angiotensin I, human |
5 mg |
$21.50 |
| |
C62H89N17O14 Mol Wt: 1296.49 [70937-97-2] |
10 mg |
$35.80 |
| |
The decapeptide precursor to angiotensin II. |
25 mg |
$64.50 |
| |
| A5277 |
Angiotensin II, human |
5 mg |
$35.80 |
| |
C50H71N13O12 FW 1046.19 [68521-88-0] |
10 mg |
$60.90 |
| |
A vasoactive agent that acts on the adrenal gland to stimulate the release of |
25 mg |
$107.50 |
| |
aldosterone. |
|
|
| |
Wallace KB, Roth RA, Hook JB et al. Am J Physiol. 238:R395-399 (1980). |
|
|
| |
| A5279 |
Angiotensin II (1-4), human |
5 mg |
$35.80 |
| |
C24H37N7O8 FW 551.6 |
10 mg |
$60.90 |
| |
|
25 mg |
$107.50 |
| |
| A5280 |
Angiotensin II (3-8), human |
5 mg |
$35.80 |
| |
C40H54N8O8 FW 774.93 |
10 mg |
$60.90 |
| |
|
25 mg |
$107.50 |
| |
| A5281 |
Angiotensin II (4-8), human |
5 mg |
$35.80 |
| |
C35H45N7O7 FW 675.79 |
10 mg |
$60.90 |
| |
|
25 mg |
$107.50 |
| |
| A5282 |
Angiotensin II [Sar1 Ile8] |
5 mg |
$35.80 |
| |
C46H74N13O10 FW 968.1 |
10 mg |
$60.90 |
| |
|
25 mg |
$107.50 |
| |
| A5283 |
Angiotensin II [Sar1] |
5 mg |
$35.80 |
| |
C49H71N13O11 FW 1018.19 |
10 mg |
$60.90 |
| |
|
25 mg |
$107.50 |
| |
| A5284 |
Angiotensin II, human [Val5] |
5 mg |
$35.80 |
| |
C49H69N13O12 FW 1032.18 |
10 mg |
$60.90 |
| |
|
25 mg |
$107.50 |
| |
| A5278 |
Angiotensin III, human |
5 mg |
$35.80 |
| |
C46H66N12O9 FW 931.1 |
10 mg |
$60.90 |
| |
The amino-terminal degradation product of AngII. It is a central regulator of |
25 mg |
$107.50 |
| |
vasopressin release and blood pressure. It has been found to activate NF-kappaB |
|
|
| |
and AP-1 and to increase MCP-1 in mesangial and mononuclear cells. |
|
|
| |
Reaux A, Fournie-Zaluski MC, Llorens-Cortes C. Trends Endocrinol Metab. 12:157-62 (2001). |
|
|
| |
Ruiz-Ortega M, Lorenzo O, Egido J. Kidney Int. 57:2285-98 (2000). |
|
|
| |
| A5285 |
[Ile7] Angiotensin III |
1 mg |
$35.80 |
| |
C43H68N12O9 FW 897.1 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
| A5287 |
Angiotensinogen (1-14), human |
1 mg |
$35.80 |
| |
C83H122N24O19 FW 1760.05 |
2 mg |
$60.90 |
| |
A precursor of Angiotensin I. Angiotensinogen is cleaved by renin as a response |
5 mg |
$107.50 |
| |
to lowered blood pressure. |
|
|
| |
Ohkubo H,Kageyama R,Ujihara M,Hirose T,Inayama S,Nakanishi S.ProcNatlAcadSciUSA.80:2196-200(1983). |
|
|
| |
| A5327 |
Anagrelide |
10 mg |
$85.00 |
| |
C10H7Cl2N3O FW 256.09 [68475-42-3] |
25 mg |
$160.00 |
| |
Phosphodiesterase inhibitor. Inhibits maturation of megakaryocytes into platelets. |
100mg |
$500.00 |
| |
Wilmes LJ. Magn Reson Imaging 25(3):319-27 |
|
|
| |
Rugo HS. J Clin Oncol. 23(24):5474-83 |
|
|
| |
| A5326 |
Aniracetam |
100mg |
$62.20 |
| |
C12H13NO3 219.24 [72432-10-1] |
500mg |
$186.40 |
| |
Cognition enhancer that potentiates AMPA receptor mediated ion conductance. |
1 g |
$303.60 |
| |
It slows the rate of channel closing and the microscopic rates of desensitization. |
|
|
| |
Antiapoptotic effects have been confirmed by the increase of intracellular ATP and phosphocreatine levels. |
|
|
| |
Lawrence JJ, Brenowitz S, Trussell LO. Mol Pharmacol. 64:269-78 (2003). |
|
|
| |
Gabryel B, Adamczyk J, Huzarska M et al. Neurotoxicology. 23:385-95 (2002). |
|
|
| |
| A5334 |
Anisodamine |
100mg |
$40.20 |
| |
C17H23NO4 FW 305.37 [55869-99-3] |
500mg |
$100.40 |
| |
Has an inhibitory effect on acetylcholine receptor channels. Found to inhibit |
1 g |
$165.60 |
| |
Shiga toxin-1-induced cytokine production, significantly decreasing lethality. |
|
|
| |
Zhang HM, Ou ZL, Gondaira F et al. J Lab Clin Med. 137:93-100 (2001). |
|
|
| |
Guo H, Lorenz RR, Vanhouette PM. Chin Med Sci J. 7:32-35 (1992). |
|
|
| |
| A5373 |
Anisomycin |
5 mg |
$30.10 |
| |
Flagecidin |
25 mg |
$94.10 |
| |
C14H19NO4 FW 265.31 [22862-76-6] |
100mg |
$281.00 |
| |
A protein synthesis inhibitor as well as an activator of p38 MAP kinase and |
|
|
| |
c-Jun N-terminal kinases. Causes apoptosis of PC12 cells. |
|
|
| |
Torocsik B, Szeberenyi J. Biochem Biophys Res Comm. 278:550-6 (2000). |
|
|
| |
Ogawa T, Hayashi T, Kyoizumi S et al. Journal of Cell Science. 117:2087-96 (2004). |
|
|
| |
| A5458 |
Anorexigenic Peptide |
1 mg |
$14.30 |
| |
C13H17N5O5 FW 323.4 [69275-10-1] |
2 mg |
$25.10 |
| |
An appetite suppressing peptide isolated from urine of anorexia nervosa patients. |
5 mg |
$43.00 |
| |
Coy et. al. J Physiol 341:225-235 (1981). |
|
|
| |
| A5460 |
ANP (1-11), rat |
1 mg |
$57.30 |
| |
C49H83N20O15S1 FW 1224.4 |
2 mg |
$292.10 |
| |
A potent natriuretic and vasodilatory peptide secreted by the heart atria. |
5 mg |
$516.10 |
| |
Hirsch JR, Meyer M, Forssmann WG. Eur J Med Res. 27:447-54 (2006). |
|
|
| |
| A5461 |
ANP (1-30), frog |
0.5 mg |
$14.30 |
| |
C131H215N49O41S4 FW 3260.73 |
1 mg |
$25.10 |
| |
|
2.5 mg |
$43.00 |
| |
| A5476 |
Antagonist G |
0.5 mg |
$107.50 |
| |
C49H62O6N12S FW 951.2 [115150-59-9] |
1 mg |
$182.80 |
| |
Antineoplastic agent |
2.5 mg |
$322.60 |
| |
An anticancer peptide. A neuropeptide growth factor antagonist. |
|
|
| |
Jones, D.A.; Cummings, J.; Langdon, S. P.; Smyth, J. F. Gen Pharmacol. 28:183-9 (1997). |
|
|
| |
| A5477 |
Antide Acetate |
Please inquire |
|
| |
C82H108ClN17O14 FW 1591.32 [112568-12-4] |
|
|
| |
| A5479 |
Antiestrogen |
0.5 mg |
$78.80 |
| |
C64H103N13O22SP FW 1469.65 |
1 mg |
$134.40 |
| |
|
2.5 mg |
$236.50 |
| |
| A5378 |
Antimycin A |
10 mg |
$62.60 |
| |
[1397-94-0] |
50 mg |
$248.40 |
| |
An inhibitor of mitochondrial respiratory chain complex III. Induces apoptosis in cell cultures. |
|
|
| |
Formigli L, Papucci L, Tani A et al. J. Cell Physiol. 182:41-9 (2000). |
|
|
| |
Mills KI, Woodgate LJ, Gilkes AF et al. Biochem Biophys Res Commun. 263:294-300 (1999). |
|
|
| |
| A5478 |
Antipain |
1 mg |
$26.80 |
| |
C27H44N10O6 F.W: 604.7 |
5 mg |
$87.40 |
| |
A natural protease inhibitor and known inhibitor of carcinogenesis induced by |
25 mg |
$309.90 |
| |
the S-phase dependent alkylating agent N-methyl-N-nitro-N-nitroso guanidine. It |
|
|
| |
has been shown to supress chromosomal aberrations in human lymphocytes and reduce |
|
|
| |
nuclear binding of estrogen-receptor complex in MCF-7 breast tumor cells. |
|
|
| |
Afzal V, Wiencke JK, Wolff S. Carcinogenesis. 10:1193-6 (1989). |
|
|
| |
Umans RS, Weichselbaum RR, Johnson CM, Kennedy AR. Carcinogenesis. 5:1355-7 (1984). |
|
|
| |
| A6002 |
Apamin |
0.5 mg |
$93.20 |
| |
C79H131N31O24S4 FW 2027.37 |
1 mg |
$157.70 |
| |
A potent neurotoxic peptide isolated in honeybee venom, blocks calcium- |
2.5 mg |
$279.60 |
| |
activated potassium channels. Apamin is know to cause thermal and mechanical hypersensitivity in rats. |
|
|
| |
Chen YN, et. al. Neuroscience. 138: 631-40 (2006). |
|
|
| |
| A6017 |
Apelin-13, human, bovine |
0.5 mg |
$57.30 |
| |
C69H111N23O16S FW 1550.86 |
1 mg |
$96.80 |
| |
An endogenous ligand for the G protein-coupled receptor. |
2.5 mg |
$172.00 |
| |
Lee D.K. et. al.J Neurochem. 74: 34-41 (2000). |
|
|
| |
| A6229 |
Aphidicolin |
1 mg |
$89.60 |
| |
C20H34O4 FW 338.48 [38966-21-1] |
5 mg |
$336.00 |
| |
DNA polymerase inhibitor. Potentiates apoptosis induced by therapeutic |
10 mg |
$588.00 |
| |
nucleosides. |
|
|
| |
Kuwakado K, Kubota M, Hirota H et al. Biochem Pharmacol. 46:1909-16 (1993). |
|
|
| |
Lin CK, Nguyen TT, Morgan TL et al. Exp Cell Res. 244:1-13 (1998). |
|
|
| |
| A6132 |
Apicidin |
1 mg |
$50.40 |
| |
C34H49N5O6 FW 623.78 [183506-66-3] |
5 mg |
$224.00 |
| |
Is a fungal metabolite with anti-parastitic activity effected by inhibiting histone |
|
|
| |
deactylase. Shows a broad spectrum or antiproliferative activity against various cancer cells. |
|
|
| |
Mazitschek, R. Bioorganic & Medicinal Chemistry Letters (2008), 18(9), 2809-2812 |
|
|
| |
Wang, J. Journal of Biological Chemistry (2007), 282(39), 28408-28418. |
|
|
| |
Ueda, T. International Journal of Molecular Medicine (2007), 19(2), 301-308. |
|
|
| |
| A6234 |
Apigenin |
5 mg |
$22.60 |
| |
C15H10O5 FW 270.24 [520-36-5] |
25 mg |
$65.30 |
| |
A nonmutagenic flavonoid, shown to inhibit cell proliferation, angiogenesis, |
100mg |
$185.70 |
| |
and protein kinase. It also induces apoptosis in breast cancer cells via the |
|
|
| |
phosphatidylinositol 3-kinase/Akt-dependent pathway. |
|
|
| |
Way TD, Kao MC, Lin JK. J Biol Chem. 279:4479-89 (2004). |
|
|
| |
Osada M, Imaoka S, Funae Y. FEBS Letters. 575:59-63 (2004). |
|
|
| |
| A6264 |
Apramycin |
1 g |
$41.40 |
| |
C21H41N5O11 FW 539.58 [37321-09-8] |
5 g |
$165.60 |
| |
Aminoglycoside antibiotic shown to be a potent inhibitor of protein synthesis in bacteria |
|
|
| |
in vivo and in vitro. It works by inhibiting the translocation step of protein synthesis. |
|
|
| |
Perzynski S, Cannon M, Cundliffe E et al. Eur J Biochem. 99:623-8 (1979). |
|
|
| |
Davies J, O'Connor S. Antimicrob Agents Chemother. 14:69-72 (1978). |
|
|
| |
| A6268 |
Aprotinin |
10 mg |
$104.40 |
| |
C284H432N84O79S7 F.W 6511.83 |
50 mg |
$287.40 |
| |
A pancreatic basic trypsin inhibitor polypeptide found in tissues and blood. |
|
|
| |
Haberland G, McConn R. Fed Proc. 38:2760-67 (1979). |
|
|
| |
| A6804 |
Arbutin |
5 g |
$46.70 |
| |
C12H16O7 FW 272.25 [497-76-7] |
10 g |
$77.60 |
| |
Antibacterial agent from traditional medicinal plants. It is present in the leaves |
25 g |
$168.70 |
| |
of bearberry, blueberry, cranberry and pear. It was found to have depigmenting |
|
|
| |
action in human melanocytes in culture. It inhibits tyrosinase activity. |
|
|
| |
Maeda K, Fukuda M. J Pharmacol Exp. Ther. 276:765-9 (1996). |
|
|
| |
Jin YH, Lee SJ, Chung MH et al. Arch Pharm Res 22:232-6 (1999). |
|
|
| |
| A6922 |
Arformoterol tartrate |
5 mg |
$145.00 |
| |
C19H24N2O4 FW 256.09 [68475-42-3] |
10 mg |
$250.00 |
| |
Long acting beta-adrenoceptor agonist. Used in the treatment of chronic |
25 mg |
$480.00 |
| |
obstructive pulmonary disease. |
|
|
| |
Bonasia, P. Current Medical Research and Opinion (2007), 23(10), 2477-2483. |
|
|
| |
| A6823 |
Argatroban |
10 mg |
$115.50 |
| |
C23H36N6O5S FW 508.64 [74863-84-6] |
25 mg |
$250.90 |
| |
A thrombin inhibitor that prevents tumor cell migration and bone metastasis. |
100 mg |
$689.90 |
| |
It has been shown to be more effective than heparin in preventing platelet loss and expression of P-selectin. |
|
|
| |
Kanemitsu S, Nishikawa M, Onoda K et al. J Thorac Cardiov Sur. 126:428-35 (2003). |
|
|
| |
Asanuma K, Wakabayashi H, Hayashi T et al. Oncology. 67:166-73 (2004). |
|
|
| |
| A6825 |
L-Arginine |
25 g |
$20.70 |
| |
C6H14N4O2 FW 174.20 [74-79-3] |
100 g |
$48.40 |
| |
Plays a role in nitric oxide synthesis that induces vasodilation in vivo. Nitric |
500 g |
$124.20 |
| |
oxide potentiates insulin-mediated glucose uptake through the increase in blood flow. |
|
|
| |
Dallinger S, Sieder A, Strametz J et al. Am J Physiol Endocrinol Metab. 284:E1106-11 (2003). |
|
|
| |
Paolisso G, Tagliamonte MR, Marfella R et al. Metabolism 46:1068-73 (1997). |
|
|
| |
| A6826 |
L-Arginine Monohydrochloride |
25 g |
$16.60 |
| |
C6H14N4O2.HCl FW 210.66 [1119-34-2] |
100 g |
$41.40 |
| |
|
500 g |
$117.40 |
| |
| A6828 |
Na,Na-Dimethyl-L-Arginine, Ammonium Salt |
10 mg |
$20.20 |
| |
C8H18N4O2.NH3 Mol. Wt. 219.28 |
25 mg |
$42.00 |
| |
Nitric oxide inhibitor in vitro and in vivo. |
100 mg |
$140.00 |
| |
Kotani K et. Al. J. Neurochem. 58:1127 (1992). |
|
|
| |
| A6829 |
NG,N'G-Dimethyl-L-Arginine, Ammonium Salt |
10 mg |
$33.90 |
| |
C8H18N4O2.NH3 Mol.Wt. 219.28 |
25 mg |
$70.60 |
| |
|
100 mg |
$235.20 |
| |
| A6827 |
Argpressin Acetate |
Please inquire |
|
| |
C46H65N15O12S2 FW 1084.23 [113-79-1] |
|
|
| |
| |
| A7034 |
Aripiprazole |
100mg |
$39.20 |
| |
C23H27Cl2N3O2 Mol. Wt: 448.39 [129722-12-9] |
250mg |
$72.80 |
| |
Used for the treatment of schizophrenia. Used for the treatment of acute manic |
1 g |
$207.20 |
| |
and mixed episodes associated with bipolar disorder, and as an adjunct for the |
|
|
| |
treatment of depression. |
|
|
| |
Lawler CP et al. (1999). Neuropsychopharmacology 20 (6): 612�27. |
|
|
| |
| A6932 |
Aristolochic acid A |
1 mg |
$103.30 |
| |
C17H11NO7 FW 341.27 [313-67-7] m.p. 287-292oC 9dec) |
5 mg |
$361.40 |
| |
Aristolochic acids are the active ingredients responsible for the hepatoxicity |
10 mg |
$550.80 |
| |
and renal toxicity of the Oriental herb Aristolochic fangchi. They form |
|
|
| |
DNA adducts in renal tissue and are associated with urothelial carcinoma formation. |
|
|
| |
They are known to induce hepatic nodules and forestomach tumors in rats. |
|
|
| |
Levi M, Guchelaar HJ, Woerdenbag HJ, Zhu YP. Pharm. World Sci. 20:43-4 (1998). |
|
|
| |
Mengs U, Stotzem CD. Arch. Tox. 67:307-11 (1993). |
|
|
| |
Schmeiser HH, Bieler CA, Wiessler M et al. Cancer Res. 56:2025-28(1996). |
|
|
| |
| A6934 |
Aristolochic acid C |
1 mg |
$103.30 |
| |
C16H9NO7 FW 327.25 |
5 mg |
$361.40 |
| |
See Aristolochic acid A |
10 mg |
$550.80 |
| |
| |
| A6970 |
Artemether |
50 mg |
$50.20 |
| |
C16H26O5 FW 298.37 |
100mg |
$72.80 |
| |
It is an oil-soluble derivative of the antimalarial agent artemesinin. |
500mg |
$276.00 |
| |
Zhao YH, Wang JY. Chinese Journal of Parasitology & Parasitic Diseases. 21:326-9 (2003). |
1 g |
$439.00 |
| |
White NJ, Waller D, Crawley J et al. Lancet. 339:317-21 (1992). |
|
|
| |
Xiao SH, Catto BA. Antimicrob Agents Chemother. 33:1557-62 (1989). |
|
|
| |
| A6978 |
Artemisinin |
100mg |
$48.60 |
| |
Qinghaosu, arteanuin |
500mg |
$182.20 |
| |
C15H22O5 FW 282.35 M.P. 156-157OC [63968-64-9] |
1 g |
$294.80 |
| |
Natural product isolated from the traditional Chinese antimalarial herb |
|
|
| |
Atremisia annua L. Cytotoxic against several tumor cell lines, |
|
|
| |
including Ehrlich ascites carcinoma cells. |
|
|
| |
Qinghaosu Antimalaria Coordinating Research Group. Chinese Med J. 92:811-816 (1979). |
|
|
| |
Zheng GQ. Planta Med. 60:54-57 (1994). |
|
|
| |
Beekman AC, Woerdenbag HJ, Van Uden W et al. J Pharm Pharmacol. 49:1254-1258 (1997). |
|
|
| |
| A6979 |
Dihydro-artemisinin |
50 mg |
$37.60 |
| |
C15H24O5 FW 284.35 |
100mg |
$56.40 |
| |
A more water-soluble analogue of artemisinin. It inhibits tumor cell |
500mg |
$200.70 |
| |
growth and suppresses angiogenesis in vitro. It has been shown |
1 g |
$307.30 |
| |
to reduce VEGF binding to its receptors on the surface of HUVEC. |
|
|
| |
Chen HH, Zhou HJ, Fang X. Pharmacological Research. 48:231-6 (2003). |
|
|
| |
Wu GD, Wang WQ, Zhou HJ et al. Cancer Chemotherapy & Pharmacology. 53:423-32 (2004). |
|
|
| |
| A6982 |
Artesunate |
50 mg |
$40.20 |
| |
C19H28O8 FW 384.42 [88495-63-0] |
100mg |
$60.30 |
| |
A semi-synthetic derivative of artemisinin that is used as an anti-malarial drug. |
500mg |
$232.10 |
| |
It has been shown to inhibit angiogenesis in vivo and in vitro. |
1 g |
$357.50 |
| |
Chen HH, Zhou HJ, Wu GD et al. Pharmacology. 71:1-9 (2004). |
|
|
| |
Zhao Y, Hanton WK, Lee KH. Journal of Natural Products. 49:139-42 (1986). |
|
|
| |
| A7085 |
Arvanil |
5 mg |
$52.80 |
| |
C28H41NO3 FW 439.63 [128007-31-8] |
|
|
| |
A capsaicin-anandamide hybrid molecule that is a CB1/VR1 agonist. It has been shown |
|
|
| |
to induce apoptosis through a FADD/caspase-8-dependent pathway, in addition to |
|
|
| |
exerting a potent analgesic effect. |
|
|
| |
Brooks JW, Pryce G, Bisogno T et al. Euro J Pharmacol. 439:83-92 (2002). |
|
|
| |
Sancho R, de la Vega L, Appendino G et al. Brit J Phamacol. 140:1035-44 (2003). |
|
|
| |
| A7208 |
Ascomycin |
1 mg |
$179.20 |
| |
C43H69NO12 FW 792.01 |
5 mg |
$806.40 |
| |
Ascomycin is an antifungal antibiotic. Its anticonvulsant effect is the result of |
|
|
| |
inhibition of calcineurin activity which is involved in picrotoxin-induced epileptic seizures. |
|
|
| |
Arai, T., Kouama, Y., Suenaga, T., Hoda, H. J. Antibiot. 15:231-232 (1962). |
|
|
| |
Vazquez-Lopez, A. Sierra-Paredes, ,G., Sierra-Marcuno, G. Pharmacol Biochem Behav. 84:511-516 (2006). |
|
|
| |
| A7210 |
L(+)-Ascorbic Acid |
100 g |
$39.20 |
| |
Vitamin C |
500 g |
$100.80 |
| |
C6H8O6 FW 176.12 [50-81-7] |
|
|
| |
An antioxidant. Vitamin C reduces DNA single strand breaks and 1-hydroxyethyl-POBN adduct |
|
|
| |
formation caused by ethanol. It has been shown to prevent oral carcinogenesis induced |
|
|
| |
by dimethyl benzanthracene. Induces apoptosis in HL-60 cells. |
|
|
| |
Navasumrit P, Ward TH, Doss NJ, O'connor PJ. Carcinogenesis. 21:93-9 (2000). |
|
|
| |
Sawant SS, kandarker SV. Oral Dis. 6:241-247 (2000). |
|
|
| |
Satoh K, Ida Y, Hosaka M et al. Anticancer Res. 18:4371-5 (1998). |
|
|
| |
| A7309 |
Ascorbyl Palmitate |
25 g |
$32.80 |
| |
6-Palmitoylascorbic acid |
100 g |
$90.60 |
| |
C22H38O7 FW 414.53 m.p. 114-1160C [137-66-6] |
500 g |
$255.60 |
| |
A lipophilic vitamin C analogue with greater stability than ascorbic acid |
|
|
| |
and enhanced antioxidant activity. A potent chemopreventive agent against colon cancer. |
|
|
| |
Rao CV, Rivenson A, Kelloff GJ et al. Anticancer Res. 15:1199-1204 (1995). |
|
|
| |
Liu XY, Guo FL, Wu LM et al. Chem Phys Lipids. 83:39-43 (1996). |
|
|
| |
Austria R, Semenzato A, Bettero A. J Pharm Biomed Anal. 15:795-801 (1997). |
|
|
| |
| A7332 |
Asiatic Acid |
100mg |
$66.80 |
| |
C30H48O5 FW 488.70 |
500mg |
$270.30 |
| |
Asiatic acid is the aglycone of asiaticoside isolated from the plant Centella asiatica |
|
|
| |
commonly used in wound healing. |
|
|
| |
Maquart FX, Chastang F, Simeon A et al. Europ. J Derm. 9:289-296 (1999). |
|
|
| |
Shukla A, Rasik AM, Jain GK et al. J. Ethnopharmacol. 65:1-11 (1999). |
|
|
| |
Yoosook C, Bunyapraphatsara N, Boonyakiat Y, Kantasuk C. Phytomedicine 6:411-419 (2000). |
|
|
| |
Medda S, Das N, Mahato SB et al. Indian J Biochem Biophys. 32:147-151 (1995). |
|
|
| |
| A7333 |
Asiaticoside |
1 mg |
$94.80 |
| |
C48H78O18 FW 943.12 [16830-15-2] m.p. 230-233oC |
5 mg |
$344.40 |
| |
Asiaticoside is a triterpene glycoside from the plant Centella asiatica commonly |
10 mg |
$550.80 |
| |
used in wound healing. This activity is a result of stimulation of collagen and |
|
|
| |
glycosaminoglycan synthesis. This glycoside was also found to have activity against |
|
|
| |
herpes simplex virus 1 and 2 and mycobacterium tuberculosis. |
|
|
| |
Maquart FX, Chastang F, Simeon A et al. Europ. J Derm. 9:289-296 (1999). |
|
|
| |
Shukla A, Rasik AM, Jain GK et al. J. Ethnopharmacol. 65:1-11 (1999). |
|
|
| |
Yoosook C, Bunyapraphatsara N, Boonyakiat Y, Kantasuk C. Phytomedicine 6:411-419 (2000). |
|
|
| |
Medda S, Das N, Mahato SB et al. Indian J Biochem Biophys. 32:147-151 (1995). |
|
|
| |
| A7462 |
Aspartame |
1 g |
$30.50 |
| |
C14H18N2O5 FW 294.30 [22839-47-0] |
5 g |
$75.90 |
| |
A dipeptide ester used as low-calorie artificial sweetener. In solution, it is |
25 g |
$303.60 |
| |
160 times sweeter than sucrose. |
|
|
| |
Aspirin (See acetylsalicylic acid) |
|
|
| |
| A7618 |
Atenolol |
1 g |
$55.20 |
| |
C14H22N2O3 FW 266.34 [29122-68-7] |
5 g |
$96.70 |
| |
A beta-adrenoceptor antagonist; antihypertensive; antianginal. |
25 g |
$310.50 |
| |
Elijovich F, Laffer CL, Schiffrin EL. I Hum Hypertens. 11:313-9 (1997). |
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Plosker GL, Clissold SP. Drugs. 43:382-414 (1992). |
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| |
| A7656 |
Atomoxetine Hydrochloride |
25 mg |
$95.20 |
| |
C17H21NO.HCl FW 281.82 [82248-59-7] |
100mg |
$313.60 |
| |
Atomoxetine is a selective noradrenaline reuptake inhibitor. It is used to treat |
250mg |
$560.00 |
| |
attention-deficit/hyperactivity disorder. |
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| |
Oberlender, R. Nichols, DE. Ramachandran PV Srebnik M, J. Pharm Pharmacol. 39:1055-1056 (1987). |
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Kratochvil CJ. Vaughan, BS. Harrington MJ Burke WJ. Expert Opin Pharmacother. 4:1165-1174 (2003). |
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| A7657 |
Atosiban Acetate |
Please inquire |
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| |
C43H67N11O12S2 FW 994.2 [90779-69-4] |
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| |
A competitive oxytocin and vasopressin antagonist by exhibiting high affinity for |
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both receptors. It is used to treat preterm labors. |
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| |
Williams et. al. Adv Exp Med Biol. 449:473-479 (1998). |
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| |
Bossmar T. J Perinant Med. 26:458-45 (1998). |
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| |
| A7668 |
Atracurium Besylate |
50 mg |
$45.80 |
| |
C65H82N2O18S2 FW 1243.50 [64228-81-5] |
100mg |
$73.90 |
| |
A competitive neuromuscular blocking agent. |
500mg |
$286.90 |
| |
Hughes R, Chapple DJ. Br J Anaesth. 53:31-44 (1981). |
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| |
| A7669 |
Atrial Natriuretic Peptide (1-28), rat |
0.5 mg |
$172.00 |
| |
C128H205N45O39S2 FW 3062.47 |
1 mg |
$292.10 |
| |
A diuretic and natriuretic peptide isolated from rat atrial myocytes that exhibits |
2.5 mg |
$516.10 |
| |
vasorelaxant activity. |
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| |
Grammer RT, Fukumi H, Inagami T, Misono KS. Biochem Biophys Res Commun. 16(2):696-703 (1983). |
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| |
| A7670 |
Atriopeptin I |
0.5 mg |
$121.90 |
| |
C83H135N29O30S2 FW 2083.31 |
1 mg |
$207.90 |
| |
A biologically active petide isolated from mammalian cardiac atria. A natriuretic |
2.5 mg |
$365.60 |
| |
and diuretic peptide that selectively relaxes intestinal but not vascular smooth muscle strips. |
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| |
Currie et. al. Science. 223:67-69 (1984). |
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| |
| A7071 |
Atriopeptin II (rat, rabbit, mouse) |
0.5 mg |
$179.20 |
| |
C98H156N34O32S2 FW 2386.67 |
1 mg |
$304.60 |
| |
A biologically active petide isolated from mammalian cardiac atria. It exhibits |
2.5 mg |
$537.60 |
| |
strong natriuretic and diuretic activities that relaxes both intestinal and vascular |
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| |
smooth muscle strips. Atriopeptin II also exhibits potent renal vasodilatating effects in rats. |
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| |
Oshima T, Currie MG, Geller DM, Needleman P. Circ Res. 54:612-616 (1984). |
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| |
| A7072 |
Atriopeptin III |
0.5 mg |
$164.90 |
| |
C107H165N35O34S2 FW 2549.85 |
1 mg |
$279.60 |
| |
An analogue of atrial natriuretic peptide that inhibits carotid body chemoreceptor |
2.5 mg |
$494.60 |
| |
nerve activity induced by hypoxia. |
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| |
He L, Dinger B, Fidone S. Am J Physiol Cell Physiol. 278: C845-852 (2000). |
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| |
| A7672 |
Atropine Sulfate |
5 g |
$55.20 |
| |
(C17H23NO3)2.H2O.H2O FW 694.84 [5908-99-6] |
10 g |
$96.70 |
| |
Antimuscarinic drug that has antagonistic activity against alpha(1)-ARs. It is |
25 g |
$241.50 |
| |
an effective bronchodilator. |
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| |
Shinoura H, Tsujimoto G, Teranishi Y et al. Naunyn Schmiedebergs Arch Pharmacol. 366:368-71 (2002). |
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| |
Klock LE, Miller TD, Morris AH et al. Am Rev Respir Dis. 112:371-6 (1975). |
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| |
| A8070 |
Auraptene |
25 mg |
$41.40 |
| |
C19H22O3 FW 298.38 [495-02-3] |
100mg |
$138.00 |
| |
Natural product from citrus fruit. Exerts tumor-preventive action through |
500mg |
$517.40 |
| |
apoptosis and cell proliferation-dependent mechanisms. Increases the activities |
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| |
of Phase II drug-metabolizing enzymes in the liver and colon. |
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| |
Tanaka T, Kawabata K, Kakumoto M et al. Cancer Res. 12:2550-6 (1998). |
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| |
Mori H, Niwa K, Zheng Q et al. Mutat Res. 480:201-7 (2001). |
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| |
| A8071 |
Auriculin A |
0.5 mg |
$164.90 |
| |
C104H168N38O33S2 FW 2542.86 |
1 mg |
$279.60 |
| |
|
2.5 mg |
$494.60 |
| |
| |
| A8077 |
Autocamtide 2 |
0.5 mg |
$64.50 |
| |
C65H118N22O20 FW 1527.8 |
1 mg |
$109.30 |
| |
|
2.5 mg |
$193.50 |
| |
| A9435 |
Axitinib |
5 mg |
$48.00 |
| |
C22H18N4OS Mol. Wt: 386.47 [319460-85-0] |
25 mg |
$175.00 |
| |
A small molecule tyrosine kinase inhibitor. |
100mg |
$560.00 |
| |
Wilmes L J Magn Reson Imaging 25(3):319-27 |
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| |
Rugo HS. J Clin Oncol. 23(24):5474-83 |
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| |
| A9801 |
Azaperone |
500mg |
$103.50 |
| |
C19H22FN3O FW 327.40 [1649-18-9] |
1 g |
$165.60 |
| |
Butyrophenone tranqulizer, and neuroleptic. Exerts an alpha adrenergic blocking |
5 g |
$662.40 |
| |
action and retards pre-adrenoreceptor activation of heart rate in pigs. |
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| |
Gregory NG, Wilkins LJ. J Vet Pharmacol Ther. 9:164-70 (1986). |
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| |
Hughes RN, Syme LA, Syme GJ. Psychopharmacology. 52:107-9 (1997). |
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| |
| A9803 |
Azathioprine |
1 g |
$44.80 |
| |
C9H7N7O2S FW 277.26 [446-86-6] |
5 g |
$168.00 |
| |
Is an immunosuppressant. It is a purine synthesis inhibitor which inhibits the |
10 g |
$280.00 |
| |
proliferation of cells. |
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| |
Chebli J. Journal of gastroenterology and hepatology (2007), 22(2), 268-74. |
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| |
Rippin S J. Clinical nephrology (2007), 67(6), 374-80. |
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| |
van de Nadort C. J. pediatric gastroenterology and nutrition (2007), 45(4), 490. |
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| |
| A9817 |
Azelaic acid |
5 g |
$39.20 |
| |
C9H16O4 FW 188.22 [123-99-9] |
25 g |
$112.00 |
| |
A naturally occurring dicarboxylic acid. It is non-toxic, non-teratogenic, and |
|
|
| |
non-mutagenic. It is cytotoxic to melanocytes of human melanoma. |
|
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| |
Nazzaro-Porro M. Passi S. Zina G. et al Lancet 1:1109-1111 (1980). |
|
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| |
| A9818 |
Azelastine HCl |
100mg |
$45.60 |
| |
C22H24ClN3O FW 381.90 [58581-89-8] |
500mg |
$129.10 |
| |
H1-Histamine receptor antagonist. It inhibits the release of leukotriene C4 and |
1 g |
$205.10 |
| |
D4, and TNF -alpha. |
|
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| |
Hamamoto Y, Nagai K, Muto M, Asagami C. Exptal Derm. 2:231-235 (1993). |
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| |
Katayama S, Tsunoda H, Sakuma Y et al. Int. Arch Allergy Appl Immun. 83:284-289 (1987). |
|
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| |
| A3212 |
3'-Azido-3'-deoxythymidine |
25 mg |
$41.10 |
| |
AZT, Azidothymidine, Zidovudine |
100mg |
$114.80 |
| |
C10H13N5O4 FW 267.24 [30516-87-1] |
250mg |
$254.00 |
| |
Antiviral agent. Effective against HIV. |
1 g |
$409.90 |
| |
| A9834 |
Azithromycin |
500mg |
$51.60 |
| |
C38H72N2O12 FW 748.98 [83905-01-5] |
1 g |
$77.60 |
| |
A 16-membered ring macrolide found to have potent antibacterial action against |
5 g |
$309.90 |
| |
gram-negative organism. |
|
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| |
Retsema J, Girard A, Schelkly W et al. Antimicrob Agents Chemother. 31:1939-47 (1987). |
|
|
| |
| A9978 |
Aztreonam |
10 mg |
$31.40 |
| |
C13H17N5O8S2 FW 435.43 [78110-38-0] |
50 mg |
$75.30 |
| |
A synthetic monobactam antibiotic. |
250mg |
$250.90 |
| |
Stutman HR, Welch DF, Scribner RK et al. Antimicrob Agents Chemother. 25:93-97 (1984). |
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| |
Paradelis AG, Stathopoulis GA, Salpigides GN et al. Method Find Exp Clin. 5:375-383 (1983). |
|
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| |
| |
AZT ( See 3'Azido-3'deoxythymidine) |
|
|