| C0016 |
Caerulomycin A |
1 mg |
$344.40 |
| |
C12H11N3O2 FW 229.23 |
|
|
| |
Pyridine derivative antibiotic. Produced by several actinomycete species. Also known as cerulomycin. |
|
|
| |
Caerulomycin A is a fungicide that exhibit activities against human tumor cells. |
|
|
| |
Divekar P V et al. Can. J. Chem. 45: 1215 (1967)� |
|
|
| |
McInnes A G et al. Can. J. Chem. 57: 3200 (1979). |
|
|
| |
|
|
|
| C0019 |
Calcifediol |
1 mg |
$98.00 |
| |
C22H44NaO2 FW 400.64 [19356-17-3] |
5 mg |
$465.00 |
| |
A prehormone which is produced by hydroxylation of vitamin D3 (cholecalciferol) in the liver |
|
|
| |
Fleet J C. American journal of physiology (1999), 276(4 Pt 1), G958-64 |
|
|
| |
|
|
|
| C0020 |
Cafestol |
50 mg |
$131.50 |
| |
C20H28O3 FW 316.44 m.p. 156-158oC [469-83-0] |
100 mg |
$204.10 |
| |
Natural product isolated from the unsaponifiable fraction of petroleum ether |
500 mg |
$719.20 |
| |
extract of coffee beans. It is an inducer of the detoxifying enzyme glutathione S-transferase. |
|
|
| |
Bengis RO, Anderson RJ. J. Biol. Chem. 47:99-113 (1932). |
|
|
| |
Slotta KH, Neisser K. Ber. 71:1991-1994 (1938). |
|
|
| |
Lam LKT, Sparnins VL, Wattenberg LW. Cancer Res. 42:1193-1198 (1982). |
|
|
| |
|
|
|
| C0021 |
Cafestol acetate |
50 mg |
$135.50 |
| |
C22H30O4 FW 358.48 m.p. 163.5-165oC [81760-48-7] |
100 mg |
$215.80 |
| |
Inducer of glutathione S-transferase. |
500 mg |
$743.50 |
| |
|
|
|
| C0025 |
Cafestol eicosanate |
25 mg |
$122.80 |
| |
C40H66O4 FW 610.95 |
50 mg |
$215.00 |
| |
|
100 mg |
$354.60 |
| |
|
|
|
| C0027 |
Cafestol linoleate |
25 mg |
$119.20 |
| |
C38H58O4 FW 578.87 |
50 mg |
$207.80 |
| |
|
100 mg |
$331.30 |
| |
|
|
|
| C0029 |
Cafestol oleate |
25 mg |
$134.40 |
| |
C38H60O4 FW 580.88 |
50 mg |
$241.80 |
| |
|
100 mg |
$367.10 |
| |
|
|
|
| C0022 |
Cafestol palmitate |
50 mg |
$138.20 |
| |
C36H58O4 FW 554.43 m.p. 43oC [81760-46-5] |
100 mg |
$215.80 |
| |
Naturally occurring ester present in green coffee beans. |
500 mg |
$743.50 |
| |
Lam LKT, Sparnins VL, Wattenberg LW. Cancer Res. 42:1193-1198 (1982). |
|
|
| |
|
|
|
| C0033 |
Cafestol stearate |
25 mg |
$114.80 |
| |
C38H62O4 FW 582.90 |
50 mg |
$203.20 |
| |
|
100 mg |
$324.20 |
| |
|
|
|
| C0121 |
Caffeic acid |
5 g |
$33.30 |
| |
C9H8O4 FW 180.16 m.p. 194-1980C 9dec.) [331-39-5] |
25 g |
$116.40 |
| |
Inhibitor of ornithine decarboxylase and protein tyrosine kinase. |
|
|
| |
Rao CV, Desai D, Kaul B, Amin S, Reddy BS. Chem. Biol.Interactions 84:277-290 (1992). |
|
|
| |
|
|
|
| C0221 |
Caffeine |
10 g |
$20.70 |
| |
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione |
50 g |
$51.60 |
| |
C8H10N4O2 FW 194.19 [58-08-2] |
100 g |
$77.60 |
| |
Caffine has inhibitory action against lung tumorigenesis, colonic carcinogenesis |
|
|
| |
and UV-induced carcinogenesis. |
|
|
| |
Chuang FL, Wang M, Rivenson A, Iatropoules MI et al. Cancer Res. 58:4096-101 (1998). |
|
|
| |
Hagiwara A, Boonyaphiphat P, Tanaka H et al. Jpn J Cancer Res. 90:399-405 (1999). |
|
|
| |
Lu YP, Lou YR, Li XH et al. Cancer Res. 60:4785-91 (2000). |
|
|
| |
|
|
|
| C0246 |
Calcimycin |
1 mg |
$44.20 |
| |
C29H37O6 FW 523.62 [52665-69-7] |
5 mg |
$103.50 |
| |
Induces apoptosis in the lens epithelium, which leads to opacification. |
10 mg |
$158.70 |
| |
Li WC, Kuszak JR, Wang GM et al. Exp. Eye Res. 61:91-8 (1995). |
|
|
| |
|
|
|
| C0247 |
Calcineurin Autoinhibitory Peptide |
0.5 mg |
$100.40 |
| |
C124H205N39O39S2 FW 2930.38 |
1 mg |
$170.20 |
| |
Specific calcineurin inhibitor. Corresponds to a C-terminal domain |
2.5 mg |
$301.10 |
| |
(residues 457-482) of the calmodulin-binding domain of calcineurin. |
|
|
| |
Hashimoto, Y.; Perrino, B. A.; Soderling, T. R. J. Biol. Chem. 265:1924(1990). |
|
|
| |
Perrino, B. A.; Ng, L. Y.; Soderlinget, T. R. J. Biol. Chem. 270:340 (1995). |
|
|
| |
|
|
|
| C0248 |
Calcineurin Substrate |
0.5 mg |
$89.60 |
| |
C92H150N28O29S FW 2112.4 |
1 mg |
$152.30 |
| |
|
2.5 mg |
$268.80 |
| |
|
|
|
| C0146 |
Calcitonin, chicken |
0.5 mg |
$107.50 |
| |
C145H240N42O46S2 FW 3371.91 |
1 mg |
$182.80 |
| |
A peptide hormone produced by thyroid cells, shown to inhibit osteoclasts activity. |
2.5 mg |
$322.60 |
| |
Liu et. al. Sheng Wu Gong Cheng Xue Bao. 22: 539-44 (2006). |
|
|
| |
|
|
|
| C0140 |
Calcitonin, eel |
1 mg |
$107.50 |
| |
C146H241N43O47S2 FW 3414.94 |
2 mg |
$182.80 |
| |
|
5 mg |
$322.60 |
| |
|
|
|
| |
|
|
|
| C0148 |
Calcitonin, human |
0.5 mg |
$96.80 |
| |
C145H240N44O48S2 FW 3417.88 |
1 mg |
$164.90 |
| |
A carrier peptide that can be used to better internalize fusion proteins. |
2.5 mg |
$292.10 |
| |
Machova Z, Muhle C, Krauss U et al. Chembiochem. 3: 672-677 (2002). |
|
|
| |
|
|
|
| C0153 |
Calcitonin, rat |
0.5 mg |
$96.80 |
| |
C148H228N40O46S3 FW 3399.9 |
1 mg |
$164.90 |
| |
|
2.5 mg |
$292.10 |
| |
|
|
|
| |
|
|
|
| C0149 |
Calcitonin, salmon |
0.5 mg |
$80.60 |
| |
C151H226N40O45S3 FW: 3417.87 |
1 mg |
$136.20 |
| |
|
2.5 mg |
$240.10 |
| |
|
|
|
| |
|
|
|
| C0244 |
a-Calcitonin Gene Related Peptide, chicken |
0.5 mg |
$179.20 |
| |
C165H260N52O50S2 FW 3836.37 |
1 mg |
$304.60 |
| |
Calcitonin gene-related peptide is important for neurotransmission, |
2.5 mg |
$537.60 |
| |
cardiovascular and respiratory function. It is released by motor neurons where it exerts |
|
|
| |
both short and long term effects on skeletal muscle fibers. |
|
|
| |
Nimmagadda D. G.S. Indian J. Pharmacol. 36:277 (2004). |
|
|
| |
Feuerstein, G. et al. Can. J. Physiol. Pharmacol. 73:1070 (1995). |
|
|
| |
|
|
|
| C0151 |
a-Calcitonin Gene Related Peptide, human |
0.5 mg |
$179.20 |
| |
C163H267N51O49S2 FW 3789.33 |
1 mg |
$304.60 |
| |
|
2.5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C0245 |
Calcitonin Gene Related Peptide, rat |
0.5 mg |
$193.50 |
| |
C162H260N50O52S2 FW 3804.33 |
1 mg |
$329.70 |
| |
|
2.5 mg |
$580.60 |
| |
|
|
|
| |
|
|
|
| C0243 |
Calcitonin Gene Related Peptide (8-37), human |
0.5 mg |
$136.20 |
| |
C139H230N44O38 FW 3125.65 |
1 mg |
$231.20 |
| |
|
2.5 mg |
$408.60 |
| |
|
|
|
| |
|
|
|
| C0249 |
Calcitonin Gene Related Peptide (8-37), rat |
0.5 mg |
$136.20 |
| |
C138H224N42O41 FW 3127.58 |
1 mg |
$231.20 |
| |
|
2.5 mg |
$408.60 |
| |
|
|
|
| |
|
|
|
| C0250 |
Calcitonin Gene Related Peptide II, human |
0.5 mg |
$179.20 |
| |
C162H267N51O48S3 FW 3793.38 |
1 mg |
$304.60 |
| |
|
2.5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C0251 |
Calcitonin Gene Related Peptide II, rat |
0.5 mg |
$179.20 |
| |
C163H265N51O50S2 FW 3803.39 |
1 mg |
$304.60 |
| |
|
2.5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C0145 |
Calcitriol |
50 �g |
$151.90 |
| |
1 alpha, 25-Dihydroxyvitamin D3 |
5 x 50 �g |
$607.20 |
| |
C27H44O3 FW 416.64 [32222-06-3] |
1 mg |
$1,517.80 |
| |
The active hormonal form of vitamin D3. Induces cell differentiation and prevents |
|
|
| |
proliferation of cancer cells. Along with dietary calcium, reduces the risk of colon cancer. |
|
|
| |
It was shown recently to be a preventive factor in the metastasis of lung cancer. |
|
|
| |
Garland C, Garland FC. Int J Epidemiol. 9:227-231 (1980). |
|
|
| |
Mehta RG, Moriarty RM, Mehta RR et al. J Natl Cancer Inst. 89:212-21(1997). |
|
|
| |
Nahagawa K, Kawauna A, Keto S et al. Carcinogenesis. 26:429-440 (2005). |
|
|
| C0147 |
Calcium Folinate, Pentahydrate |
100 mg |
$38.60 |
| |
5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt, Leucovorin |
500 mg |
$162.80 |
| |
C20H21CaN7O7.5H2O FW 601.58 [6035-45-6] |
1 g |
$273.30 |
| |
When administered after methotrexate. It supplies cells with tetrahydrofolate and diminishes |
|
|
| |
methotrexate toxicity without abolishing the antitumor effect. |
|
|
| |
Stoller RG, Hande KR. Jacobs SA et al. New Eng. J. Med. 297:630-634 (1977). |
|
|
| |
|
|
|
| C0344 |
Calphostin C |
100 �g |
$242.70 |
| |
C46H38O13 FW 798.79 [121263-19-2] |
|
|
| |
A highly specific inhibitor of PKC. Acts as at the regulatory domain. Induces |
|
|
| |
apoptosis in HL-60 human promyelocytic leukemia cells and human glioblastoma cells. |
|
|
| |
Jarvis, W.D., Yurner, A.J., Povirk, L.F., et al. Cancer Res. 54:1707-14 (1994). |
|
|
| |
Begemann, M., Kashimawo, S.A., Lunn, R.M., et al. Anticancer Res. 18:3139-52 (1998). |
|
|
| |
|
|
|
| C0346 |
Calyculin A |
10 �g |
$139.40 |
| |
C50H81N4O15P FW 1009.17 [101932-71-2] |
50 �g |
$491.80 |
| |
Protien phosphatase inhibitor. Induces apoptosis in epithelial tumor cell line, |
|
|
| |
HeLa and KB, and human breast tumor cells. |
|
|
| |
Von Zezschwitz C, Vorwerk H, Tergau F, Steinfelder HJ. FEBS Lett. 413:147-51 (1997). |
|
|
| |
Kiguchi K, Glesne D, Chubb CH et al. Cell Growth Differ. 5:995-1004 (1994). |
|
|
| |
|
|
|
| |
|
|
|
| C0150 |
Camptothecin |
25 mg |
$29.50 |
| |
C20H16N2O4 FW 348.35 m.p. 276-278oC [7689-03-4] |
100 mg |
$95.10 |
| |
A cytotoxic antitumor agent, that acts by inhibition of topoisomerase I. |
250 mg |
$213.00 |
| |
Hertzberg RP, Caranfa MJ, Hecht SM. Biochemistry. 28:4629-4638 (1989). |
|
|
| |
|
|
|
| |
|
|
|
| C0152 |
Camptothecin, 9-amino |
10 mg |
$127.50 |
| |
C20H17N3O4 FW 363.37 [91421-43-1] |
25 mg |
$265.70 |
| |
An active derivative of camptothecin, which belongs to the general group of |
50 mg |
$442.80 |
| |
chemotherapy drugs called topoisomerase inhibitors. |
|
|
| |
Takimoto, C.H.; Thomas, R. Ann. N.Y. Acad. Sci. 922: 224-36 (2000). |
|
|
| |
|
|
|
| |
|
|
|
| C0154 |
Camptothecin, 7-ethyl-10-hydroxy |
10 mg |
$123.00 |
| |
SN38 |
50 mg |
$459.10 |
| |
C22H20N2O5 FW 392.40 |
100 mg |
$737.70 |
| |
The active metablite of irinotecan that is a topoisomerase I inhibitor. |
|
|
| |
Kaneda N, Nagata H, Furuta T, Yokokura T. Cancer Research. 50:1715-20 (1990). |
|
|
| |
|
|
|
| C0155 |
Camptothecin, 10-hydroxy |
25 mg |
$46.70 |
| |
C20H16N2O5 FW 364.35 [19685-09-7] |
100 mg |
$130.50 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C0156 |
Camptothecin, 9-nitro-20(S) |
25 mg |
$57.50 |
| |
C20H19N3O6 FW 397.38 |
50 mg |
$98.40 |
| |
Active derivative of camptothecin. Induces apoptosis and inhibits HIV. |
100 mg |
$164.00 |
| |
Chatterjee D. Schmitz I. Krueger A et al. Cancer Res. 61:7148-54 (2001). |
|
|
| |
Hung CL. Doniger J. Palini A et al. J Med Virology. 64:238-44 (2001). |
|
|
| |
|
|
|
| C0253 |
Candesartan |
100 mg |
$50.40 |
| |
C24H20N6O3 Mol. Wt.: 440.45 [139481-59-7 ] |
250 mg |
$89.60 |
| |
An angiotenin II receptor antagonist used to treat hypertension |
1 g |
$280.00 |
| |
Kumagai, H. Therapeutic Research (2003), 24(11), 2036-2043. |
|
|
| |
|
|
|
| |
|
|
|
| C0254 |
Candesartan Celexetil Ester |
100 mg |
$45.00 |
| |
C33H34N6O6 FW 610.66 [145040-37-5] |
250 mg |
$80.00 |
| |
Candesartan 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester |
1 g |
$250.00 |
| |
An angiotenin II receptor antagonist used to treat hypertension |
|
|
| |
Kumagai, H. Therapeutic Research (2003), 24(11), 2036-2043. |
|
|
| |
|
|
|
| |
Canrenoic acid potassium salt (See Potassium Canrenoate) |
|
|
| |
|
|
|
| C0160 |
Canrenone |
1 g |
$34.50 |
| |
C22H28O3 FW 340.46 [976-71-6] |
5 g |
$103.50 |
| |
Active metabolite of spironolactone. Inhibits aldosterone biosynthesis. |
25 g |
$414.00 |
| |
Blocker of ouabin effects. |
|
|
| |
Cittadini et al. Cardiovasc Res. 58:555-64 (2003). |
|
|
| |
Balzan S, Nicolini G, Bellitto L et al. J Cardiovasc Pharmacol. 42:32-6 (2003). |
|
|
| |
Datta P, Dasgupta A. Ther Drug Monit. 25:478-82 (2003). |
|
|
| |
|
|
|
| C0168 |
Canthaxanthin |
5 g |
$50.40 |
| |
C40H52O2 FW 564.84 [514-78-3] |
10 g |
$95.20 |
| |
An antioxidant that suppresses cell proliferation in oral cancer cells. |
25 g |
$153.80 |
| |
Tanak T, Makita H, Ohnishi M et al. Cancer Res. 55:4059-4064 (1995). |
|
|
| |
|
|
|
| C0162 |
Capecitabine |
250 mg |
$50.00 |
| |
C15H22FN3O6 FW 359..35 [154361-60-9] |
1 g |
$160.00 |
| |
A chemotherapeutic agent used in the treatment of metastatic breast and |
5 g |
$600.00 |
| |
colorectal cancers. A prodrug that is enzymatically converted to 5-fluorouracil in |
|
|
| |
the tumor where it inhibits DNA synthesis and slows growth of tumor tissue |
|
|
| |
Fischer, D. S. The Cancer Chemotherapy Handbook (6th Edition). Mosby. |
|
|
| |
|
|
|
| C0260 |
Capsanthin |
50 g |
$78.70 |
| |
C40H56O3 FW 584.87 [465-42-9] |
100 g |
$123.00 |
| |
A natural carotenoid isolated from red paprika. It has chemopreventive and anti-tumor activity. |
|
|
| |
Nishino H et al. Cancer Metastasis Rev. 21:257-64 (2002). |
|
|
| |
Perez-Galvez A, Martin HD, Sies H, Stahl W. Br J Nutr. 89:787-93 (2003). |
|
|
| |
|
|
|
| C0266 |
Capsaicin, natural |
100 mg |
$41.10 |
| |
C18H27NO3 FW 305.41 [404-86-4] |
250 mg |
$49.30 |
| |
Capsaicin, �65%, dihydrocapsaicin, ~20%, nordihydrocapsaicin, ~4 %. |
1 g |
$106.50 |
| |
|
|
|
| C0362 |
Capsiate |
100 mg |
$75.00 |
| |
C19H28O3 FW 304.42 |
250 mg |
$150.00 |
| |
A natural product derived from sweet peppers that has shown anti-oxidative, |
1 g |
$375.00 |
| |
anti-inflammatory and anti-cancer properties. |
|
|
| |
Pyun, Bo-Jeong. Cancer Research (2008), 68(1), 227-235. |
|
|
| |
Faraut, B. American Journal of Physiology (2007), 292(5, Pt. 1), E1474-E1482. |
|
|
| |
Hachiya, S. Bioscience, Biotechnology, and Biochemistry (2007), 71(3), 671-676. |
|
|
| |
|
|
|
| C0261 |
Captopril |
1 g |
$36.10 |
| |
C9H15NO3S FW 217.29 m.p. 103-104oC [62571-86-2] |
5 g |
$98.60 |
| |
The first orally active inhibitor of angiotensin-converting enzyme. A |
25 g |
$320.50 |
| |
reversible and competitive inhibitor of LTA4 hydrolase. |
|
|
| |
Kostis J. Am Heart J. 116: 1591 (1988). |
|
|
| |
Orning L et al. J Biol Chem. 266:16507 (1991). |
|
|
| |
|
|
|
| C0268 |
Carbadox |
25 g |
$27.70 |
| |
C11H10N4O4 FW 262.22 [6804-07-5] |
100 g |
$82.90 |
| |
Broad spectrum antimicrobial agent. |
|
|
| |
Prapasarakul N, Ochi K, Adachi Y . J Vet Med Sci. 65:1275-80 (2003). |
|
|
| |
Drumev D. Vet Med Nauki. 18:10-25 (1981). |
|
|
| |
|
|
|
| C0270 |
Carbamazepine |
1 g |
$16.60 |
| |
C15H12N2O FW 236.27 [298-45-4] |
5 g |
$34.50 |
| |
Cytochrome P450 3A4 inducing anti-epileptic drug. It increases metabolism of |
25 g |
$110.40 |
| |
CPT11 and Paclitaxel, and many tyrosine kinase inhibitors. Used in the treatment |
|
|
| |
of shooting neuralgic pain attacks. |
|
|
| |
van den Bent MJ. Eur J Cancer. 39:2114-20 (2003). |
|
|
| |
Lindner V, Deuschl G. Schmerz.18:53-60 (2004). |
|
|
| |
|
|
|
| C0169 |
Carbenoxolone |
1 g |
$30.00 |
| |
C34H50O7 FW 570.76 m.p. 291-2940C [5697-56-3] |
5 g |
$98.60 |
| |
A triterpenoid chemopreventive agent. |
25 g |
$333.40 |
| |
Rao CV, Rivenson A, Kelloff GJ, Reddy BS. Anticancer Res. 15:1199-1204 (1995). |
|
|
| |
|
|
|
| |
|
|
|
| C0170 |
N-(4-Carbethoxyphenyl)retinamide |
100 mg |
$49.30 |
| |
C29H37NO3 FW 447.61 |
500 mg |
$164.00 |
| |
A derivative of the chemopreventive agent fenretinide. |
1 g |
$255.80 |
| |
|
|
|
| C0175 |
Carbetocin Acetate |
Please Inquire |
|
| |
C45H69N11O12S FW 988.17 |
|
|
| |
|
|
|
| |
|
|
|
| C0172 |
Carbimazole |
1 g |
$34.50 |
| |
C7H10N2O2S FW 186.23 [22232-54-8] |
5 g |
$117.00 |
| |
Thyroid inhibitor. |
10 g |
$206.60 |
| |
Wise PH, Marion M, Tain R. Clin Endocrinol (Oxf)10:655-64 (1979). |
|
|
| |
|
|
|
| C0171 |
Carboplatin |
25 mg |
$46.70 |
| |
cis-Diammine[1,1-cyclobutane dicarboxylato] platinum |
100 mg |
$158.30 |
| |
C6H12N2O4Pt FW 371.3 [41575-94-4] |
250 mg |
$316.50 |
| |
An analogue of cisplatin. It is an antitumor agent. |
|
|
| |
Smith IE et al. Cancer Treat. Rep 69:43 (1985). |
|
|
| |
Calvert AH et al. Cancer Chemother. Pharmacol. 9:140 (1982). |
|
|
| |
|
|
|
| C0174 |
Carmofur |
1 g |
$53.20 |
| |
C11H16FN3O3 FW 257.26 [61422-45-5] |
5 g |
$227.70 |
| |
Orally active cytostatic derivative of fluorouracil. |
|
|
| |
Noda T, Kosakai H, Tsujimura, K et al. Gan Kagaki Ryoho 10:1972-1979 (1983). |
|
|
| |
Grohn P, Heinonen E, Kumpulainen E, et al. Am. J. Clin. Oncology. 13:477-179 (1990). |
|
|
| |
|
|
|
| C0173 |
Carmustine |
25 mg |
$41.30 |
| |
C5H9Cl2N3O2 FW 214.05 [154-93-8] |
100 mg |
$155.00 |
| |
Also known as BCNU. An antitumor alkylating agent used in the treatment of malignant glioma. |
|
|
| |
Engelhard, HH. Surg Neuraol 53:458-64 (2000). |
|
|
| |
Carter SK, Schabel FM Jr, Broder LE, Johnston TP. Adv. Cancer Res 16:273-332 (1972). |
|
|
| |
|
|
|
| C0262 |
L-Carnitine |
1 g |
$13.20 |
| |
C7H15NO3 FW 161.20 [541-15-1] |
5 g |
$34.50 |
| |
A neuromodulator and antiaging agent. Plays a vital role in fatty acid transport |
25 g |
$138.00 |
| |
across the mitochondrial membrane. Prevents neurotoxicity caused by drug abuse. Vitamin-like nutrient. |
|
|
| |
Juliet PA, et al |
|
|
| |
A Biol Sci Med Sci. 58:970-4 (2003). |
|
|
| |
|
|
|
| C0263 |
L-Carnitine HCl |
1 g |
$12.40 |
| |
C7H15NO3HCl FW 197.66 [66454-46-1] |
5 g |
$31.80 |
| |
See L-Carnithine |
25 g |
$124.20 |
| |
|
|
|
| C0264 |
L-Carnitine tartrate |
1 g |
$12.40 |
| |
2(C7H15NO3)2.C4H6O6 FW 472.49 [36687-82-8] |
5 g |
$31.80 |
| |
The preferred forms are L-carnitine (68%) and natural L-tartaric acid (32%). |
25 g |
$124.20 |
| |
|
|
|
| C0265 |
Carnosic acid, 90 % |
25 mg |
$77.60 |
| |
C20H28O4 FW 332.43 |
50 mg |
$129.20 |
| |
Antioxidant isolated from Rosemary. Has shown chemoprotective effects. |
|
|
| |
Richheimer, SL, Bernart M W, King Greg A et al. JAOCS 73:507-14 (1996). |
|
|
| |
Danilenko M, Wan X, Studzinski GP. J Natl Cancer Inst. 93:1224-33 (2001). |
|
|
| |
Offord EA, Mace K, Avanti O, Pfeifer AM. Cancer Letters. 114:275-81 (1997). |
|
|
| |
|
|
|
| C0267 |
Carnosol |
1 mg |
$79.10 |
| |
C20H26O4 FW 330.42 [5957-80-2] |
5 mg |
$316.20 |
| |
A naturally occurring phytopolyphenol found in Rosemary that functions as an |
|
|
| |
antioxidant, antimicrobial, and anticarcinogen. It has been shown to inhibit the |
|
|
| |
induction of COX-2 by blocking PKC signaling. |
|
|
| |
Subbaramaiah K, Cole PA, Dannenberg AJ. Cancer Res. 62:2522-30 (2002). |
|
|
| |
Lo AH, Liang YC, Lin-Shiau SY et al. Carcinogenesis. 23:983-91 (2002). |
|
|
| |
|
|
|
| C0269 |
b-Carotene |
1 g |
$32.30 |
| |
C40H56 FW 536.87 [7235-40-7] |
5 g |
$91.40 |
| |
An antioxidant known to inhibit carcinogenisis. Found to decrease |
|
|
| |
levels of IQ-DNA adducts in animal hepatocytes. |
|
|
| |
Rousseau EJ, Davison AJ. Free Radic Biol Med. 13:407-433 (1992). |
|
|
| |
Uehara N, Iwahori Y, Asamoto M et al. Jpn J Cancer Res. 87:342-348 (1996). |
|
|
| |
|
|
|
| C0351 |
Carprofen |
1 g |
$39.20 |
| |
C15H12ClNO2 FW 273.71 [52263-47-5] |
5 g |
$140.00 |
| |
Is a non-steroidal anti-inflammatory drug whose mechanism of action is dependent |
|
|
| |
upon inhibiting the production of cox-2 and other sources of prostaglandins |
|
|
| |
Leblanc, Y. Bioorganic & Medicinal Chemistry Letters (1995), 5(18), 2123-8. |
|
|
| |
Mancini, J. A. J. Biological Chemistry (1995), 270(49), 29372-7. |
|
|
| |
Greig, G. M. Molecular Pharmacology (1997), 52(5), 829-838. |
|
|
| |
|
|
|
| C0370 |
Carrageenan Sodium |
5 g |
$17.10 |
| |
[9000-07-1] |
25 g |
$43.10 |
| |
Structural polysaccharide of the red sea weed. |
|
|
| |
Used to induce inflammation in experimental animals. |
|
|
| |
|
|
|
| C0365 |
Carvedilol |
1 g |
$66.30 |
| |
C24H26N2O4 FW 406.47 [72956-09-3] |
5 g |
$248.40 |
| |
A non-selective b1-adrenergic antagonist. It protects against induced |
10 g |
$441.60 |
| |
mitochondrial cardiomyopathy. |
|
|
| |
Flordellis CS, Goumenos D, Kourounis G et al. J. Curr Top Med Chem. 4:487-98 (2004). |
|
|
| |
Santos DL, Moreno AJ, Leino RL et al. Toxicol Appl Pharmacol. 185:218-27 (2002). |
|
|
| |
|
|
|
| C0368 |
Carveol |
5 g |
$29.00 |
| |
C10H16O FW 152.23 [99-48-9] |
25 g |
$92.30 |
| |
A terpene that inhibits mammary carcinogenesis. |
|
|
| |
Crowell PL, Keenan WS et al. Carcinogenesis. 13:1261-1264 (1992). |
|
|
| |
|
|
|
| C0372 |
Casein Kinase 2 Assay Kit |
1 mg |
$125.40 |
| |
C45H73N19O24 FW 1264.2 |
2 mg |
$211.50 |
| |
|
5 mg |
$372.70 |
| |
|
|
|
| C0374 |
b-Casomorphin, human |
5 mg |
$50.20 |
| |
C44H61N7O11 FW 8641.02 |
10 mg |
$86.00 |
| |
|
25 mg |
$150.50 |
| |
|
|
|
| C0375 |
Caspase 3, Substrate, Colorimetric |
1 mg |
$37.60 |
| |
C26H34N6O13 FW 638.6 |
2 mg |
$64.50 |
| |
|
5 mg |
$111.10 |
| |
|
|
|
| C0275 |
Castanospermine |
10 mg |
$47.00 |
| |
C8H15NO4 FW 189.21 [79831-76-8] |
50 mg |
$188.20 |
| |
A plant alkyloid which is a potent inhibitor of alpha and beta glucosidase |
100 mg |
$280.00 |
| |
activity in fibroblast extracts. It has also been known to inhibit the glycoprotein |
|
|
| |
processing cycle and exhibits strong anti-viral properties as well as preventing angiogenesis. |
|
|
| |
Vyavahare V. P. J. medicinal chemistry (2007), 50(22), 5519-23. |
|
|
| |
Benltifa M. Bioorganic & medicinal chemistry letters (2008), 18(9), 2805-8. |
|
|
| |
Gloster, T. M. J. American Chemical Society (2007), 129(8), 2345-2354 |
|
|
| |
|
|
|
| C0379 |
Catch-Relaxing Peptide (CARP) |
1 mg |
$43.00 |
| |
C36H67N11O7S2 FW 830.13 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
|
|
|
| C0277 |
Catechins, 90 % (See G6817 Green Tea Polyphenols) |
|
|
| |
|
|
|
| |
|
|
|
| C0278 |
Catechin, 99 % |
1 mg |
$34.50 |
| |
C15H14O6 FW 290.27 [154-23-4] |
5 mg |
$86.10 |
| |
A natural flavonoid that has chemopreventive and antitumor properties. |
|
|
| |
Azuine M A, Bhide SV. Journal of Ethnopharmaclogy. 44:211-7 (1994). |
|
|
| |
Bhattacharyya J, Biswas S, Datta AG. Curr Med Chem.11:359-68 (2004). |
|
|
| |
|
|
|
| C0376 |
Catharanthine base |
25 mg |
$88.10 |
| |
C21H24N2O2 FW 336.43 [2468-21-5] |
100 mg |
$220.20 |
| |
It is one of the many alkaloids present in Catharanthus roseus. Can be used as a |
500 mg |
$827.30 |
| |
starting material for the synthesis of the anti-tumor drugs vinblastine and vincristine. |
|
|
| |
It is less active as an inhibitor of tubulin self-assembly into microtubules |
|
|
| |
than the latter two compounds. |
|
|
| |
Uniyal GC, Bala S, Mathur Ak et al. Phytochem Anal. 12:206-210 (2001). |
|
|
| |
Prakash V, Timasheff SN. Biochemistry. 30:873-880 (1991). |
|
|
| |
Pennanen S, Huhtikangas A. Photochem Photobiol. 51:515-518 (1990). |
|
|
| |
|
|
|
| C0377 |
Catharanthine sulfate |
25 mg |
$72.90 |
| |
C21H24N2O2.H2S04 FW 434.51 |
100 mg |
$209.60 |
| |
Catharanthine is a precursor of vinblastine-type alkaloids. It was found to |
500 mg |
$789.40 |
| |
have antitumor activity. |
|
|
| |
Zhao J, Hu Q, Guo YQ, Zhu WH. Appl Microbiol Biotechnol. 55:693-8 (2001). |
|
|
| |
|
|
|
| C0378 |
Catharanthine tartrate |
25 mg |
$72.90 |
| |
C21H24N2O2.C4H6O6 FW 486.52 |
100 mg |
$209.60 |
| |
|
500 mg |
$789.40 |
| |
|
|
|
| |
|
|
|
| C0476 |
CB-TH |
1 mg |
$139.80 |
| |
C138H230N46O34S4 FW 3205.9 |
2 mg |
$236.50 |
| |
A hybrid peptide containing the N-terminal residue of cecropin B (CB) and |
5 mg |
$419.30 |
| |
C-terminal end of thanatin (TH) that shows antimicrobial activity. |
|
|
| |
Hongbiao,W.; Baolong, N.; Mengkui, X.; Lihua, H.; Weifeng, S.; Zhiqi, M. J. Pept. Res. 66:382-6 (2005). |
|
|
| |
|
|
|
| |
CCNU (See lomustine) |
|
|
| |
|
|
|
| C1600 |
CEA (605-613) |
1 mg |
$139.80 |
| |
C43H69N11O14 FW 964.09 |
2 mg |
$236.50 |
| |
|
5 mg |
$419.30 |
| |
|
|
|
| C1601 |
CEA (605-613) analogue |
1 mg |
$43.00 |
| |
C43H68N10O15 FW 965.08 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
|
|
|
| C1609 |
Cecropin B |
1 mg |
$207.90 |
| |
C176H305N52O41S FW 3834.76 [80451-05-4] |
2 mg |
$353.00 |
| |
Antibacterial peptide isolated from pig intestine and moths. |
5 mg |
$623.60 |
| |
Lee, J.-Y., et al. Proc. Nat. Acad. Sci. USA 86:9159-9162 (1989). |
|
|
| |
|
|
|
| C1619 |
CEF3 |
1 mg |
$43.00 |
| |
C42H74N10O12 FW 911.12 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
|
|
|
| C1621 |
CEF4 |
1 mg |
$43.00 |
| |
C53H93N15O13 FW 1148.42 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
|
|
|
| C1622 |
CEF6 |
1 mg |
$43.00 |
| |
C48H78N10O14S FW 1051.28 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
|
|
|
| C1623 |
CEF10 |
1 mg |
$43.00 |
| |
C39H71N9O11S FW 906.2 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
|
|
|
| C1627 |
Cefaclor |
500 mg |
$69.00 |
| |
C15H13ClN3O4S.H2O FW 385.83 [70356-03-5] |
1 g |
$110.40 |
| |
Antimicrobial agent. It has a broad spectrum of activity against the most |
5 g |
$414.00 |
| |
prevalent gram-positive and gram-negative respiratory tract pathogens. |
|
|
| |
Stock I, Sherwood KJ, Wiedemann B. Diagn Microbiol Infect Dis. 48:5-15 (2004). |
|
|
| |
Guay DR. Clin Ther. 24:473-8 9 (2002). |
|
|
| |
Meyers BR. Clin Ther. 22:154-66 (2000). |
|
|
| |
|
|
|
| C1629 |
Cefoperazone Acid |
1 g |
$55.20 |
| |
C25H27N9O8S2 FW 645.67 [62893-19-0] |
5 g |
$165.60 |
| |
Antimicrobial agent that possesses potent beta-lactamase-inhibitory properties. |
|
|
| |
Jamieson CE, Lambert PA, Simpson IN. Antimicrob Agents Chemother. 47:1652-7 (2003). |
|
|
| |
Cuchural GJ Jr. Pharmacotherapy. 11(2 ( Pt 2)):51S-55S (1991). |
|
|
| |
|
|
|
| C1630 |
Cefoperazone Sodium |
1 g |
$48.40 |
| |
C25H26N9NaO8S2 FW 667.65 [62893-20-3] |
5 g |
$138.00 |
| |
Antimicrobial agent. Used for prevention of postoperative infection. It inhibits |
|
|
| |
the inactivation of alpha(1)-antitrypsin. |
|
|
| |
Uchiyama K, Kawai M, Onishi H et al. Dig Dis Sci. 48:1955-9 (2003). |
|
|
| |
Dallegri F, Dapino P, Arduino N et al. Antimicrob Agents Chemother. 43:2307-10 (1999). |
|
|
| |
|
|
|
| C1632 |
Cefotaxime Acid |
500 mg |
$69.00 |
| |
C16H17N5O7S2 FW 455.47 [63527-52-6] |
1 g |
$113.20 |
| |
Antimicrobial agent. It is effective against postoperative complications in |
5 g |
$441.60 |
| |
surgical treatment of pulmonary, tracheal and mediastinal tumors. |
|
|
| |
Petrova MV, Korniak AV, Krasnova TE. Anesteziol Reanimatol. 5:58-60 (2001). |
|
|
| |
Kern WV, Cometta A, De Bock R et al. N Engl J Med. 341:312-8 (1999). |
|
|
| |
|
|
|
| C1633 |
Cefotaxime Sodium |
500 mg |
$55.20 |
| |
C16H16N5NaO7S2 FW 477.45 [64485-93-4] |
1 g |
$96.70 |
| |
Antimicrobial agent. It is used for prevention of postoperative infection in |
5 g |
$393.30 |
| |
patients who undergo head and neck cancer surgery with major flap reconstruction. |
|
|
| |
Bhathena HM, Kavarana NM. Acta Chir Plast. 40:36-40 (1998). |
|
|
| |
|
|
|
| C1635 |
Ceftazidime |
1 g |
$71.80 |
| |
C22H22N6O7S2 FW 546.58 [72558-82-8] |
5 g |
$289.90 |
| |
Antimicrobial agent. It is used for treating febrile neutropenia in patients with cancer. |
|
|
| |
Hung KC, Chiu HH, Tseng YC et al. J Microbiol Immunol Infect. 36:254-9 (2003). |
|
|
| |
Mustafa MM, Carlson L, Tkaczewski I et al. Pediatr Infect Dis J. 20:362-9 (2001). |
|
|
| |
|
|
|
| C1620 |
Ceftiofur Hydrochloride |
500 mg |
$39.20 |
| |
C19H17N5O7S3.HCl FW 560.02 [104010-37-9] |
1 g |
$56.00 |
| |
An antibiotic of the cephalosporin type. It has activity against most gram |
5 g |
$196.00 |
| |
positive and gram negative bacteria. |
|
|
| |
Zioga, A. Journal of Antimicrobial Chemotherapy (2008), 61(6), 1389-1390. |
|
|
| |
Diarrassouba, F. Journal of Food Protection (2007), 70(6), 1316-1327. |
|
|
| |
Zioga, A. Journal of Antimicrobial Chemotherapy (2008), 61(6), 1389-1390. |
|
|
| |
|
|
|
| C1637 |
Ceftriaxone sodium |
250 mg |
$48.40 |
| |
C18H16N8O7S3Na2 FW 598.54 [104376-79-6] |
500 mg |
$75.90 |
| |
A broad-spectrum antimicrobial agent. It is used also in the treatment of febrile |
1 g |
$124.20 |
| |
granulocytopenic children with cancer. |
|
|
| |
Gorschluter M et al. Support Care Cancer. 11:362-70 (2003). |
|
|
| |
|
|
|
| C1648 |
a-Cembrenediol |
10 mg |
$146.90 |
| |
C20H34O2 FW 306.48 |
|
|
| |
A compound found in cigarette smoke condensate and were shown to inhibit tumor promotion by |
|
|
| |
tetradecanoylphorbol acetate by inhibiting the early antigen of the Epstein-Bar virus. |
|
|
| |
Degradation products are responsible for tobacco flavors. |
|
|
| |
Saito, Y., Tsujino, Y., Kaneko, H., Yoshida, D., Mizusaki, S. Agric. Biol. Chem. 51:941 (1987). |
|
|
| |
Crombie, L.; McNamara, D.; Firth, D. F.; Smith, S.; Bevana, P. C. Phytochemistry 27:1685-1693 (1988). |
|
|
| |
|
|
|
| C1649 |
b-Cembrenediol |
10 mg |
$146.90 |
| |
C20H34O2 FW 306.48 [57605-81-9] |
|
|
| |
A compound found in cigarette smoke condensate and were shown to inhibit tumor promotion by |
|
|
| |
tetradecanoylphorbol acetate by inhibiting the early antigen of the Epstein-Bar virus. |
|
|
| |
Degradation products are responsible for tobacco flavors. |
|
|
| |
Saito, Y., Tsujino, Y., Kaneko, H., Yoshida, D., Mizusaki, S. Agric. Biol. Chem. 51:941 (1987). |
|
|
| |
Crombie, L.; McNamara, D.; Firth, D. F.; Smith, S.; Bevana, P. C. Phytochemistry 27:1685-1693 (1988). |
|
|
| |
|
|
|
| C1718 |
Cepharanthine, 98% |
100 mg |
$30.90 |
| |
C37H38N2O6 FW 606.71 [481-49-20 m.p. 145-1550C |
500 mg |
$112.10 |
| |
Cepharanthine is a biscoclaurine alkaloid isolated from Stephania cepharantha |
1 g |
$172.10 |
| |
Hayata. It has anti-inflammatory, anti-allergic and immunomodulatory activity |
|
|
| |
Kondo Y, Takano F, Hojo H. Biochem. Pharmacol. 46:1887-1892 (1993). |
|
|
| |
Okamoto M, Okamoto T, Baba M. Antimicrob Agents Chemother. 43:492-497 (1999). |
|
|
| |
|
|
|
| C1867 |
Ceramide-C16 |
5 mg |
$144.30 |
| |
C34H67NO3 FW 537.90 [24696-26-2] |
25 mg |
$531.30 |
| |
A constituent of arthropod spingolipids. Ceramides are important intracellular second messengers |
|
|
| |
that play a role in the regulation of cell growth, differentiation, and programmed cell death. |
|
|
| |
Fillet M, Bentires-Alj M, Deregowski V, Greimers R et al. Biochem Pharmacol. 65:1633-42 (2003). |
|
|
| |
Aschrafi A, Franzen R, Shabahang S et al. Acta. 1634:30-9 (2003). |
|
|
| |
|
|
|
| C1868 |
Cerebellin |
1 mg |
$143.40 |
| |
C69H113N23O23 FW 1632.81 |
2 mg |
$243.70 |
| |
A cerebellum peptide used as a Purkinje cell marker for monitoring |
5 mg |
$430.10 |
| |
neurodevelopment. |
|
|
| |
Slemmon JR, Danho W, Hempstead JL, Morgan JI. Proc Natl Acad Sci U S A. 82: 7145-8 (1985). |
|
|
| |
|
|
|
| C1668 |
Cerivastatin |
1 mg |
$50.40 |
| |
C26H34FNO5 FW 459.55 [145599-86-6] |
5 mg |
$168.00 |
| |
A synthetic statin used to lower cholesterol and prevent cardiovascular disease. |
25 mg |
$560.00 |
| |
Ahmad, S. Journal of Medicinal Chemistry (2008), 51(9), 2722-2733. |
|
|
| |
|
|
|
| C1869 |
Cerulenin |
1 mg |
$39.60 |
| |
C12H17NO3 FW 223.27 [17397-89-6] |
5 mg |
$103.30 |
| |
Noncompetitive inhibitor of fatty acid synthase. It induces apoptosis in |
10 mg |
$172.10 |
| |
tumor cell lines. |
|
|
| |
Pizer ES, Jakisch C, Wood FD et al. Cancer Res. 56:2745-7 (1996). |
|
|
| |
Furuya, Y., Akimoto, S., Yasuda, K., Ito, H. Anticancer Res. 17:4589-93 (1997). |
|
|
| |
|
|
|
| C1745 |
Cetirizine (See C1876 Certizine 2HCl) |
|
|
| |
|
|
|
| C1876 |
Cetirizine 2HCl |
5 g |
$54.00 |
| |
C21H25ClN2O3.2HCl FW 461.81 [83881-52-1] |
10 g |
$86.00 |
| |
A carboxylated metabolite of hydroxyzine that has been shown to block the influx of |
25 g |
$150.00 |
| |
eosinophils into the site of antigen-stimulated skin blisters. |
|
|
| |
Snyder SH, Snowman AM. Ann Allergy. 59(6 Pt 2):4-8 (1987). |
|
|
| |
Naclerio RM. Allergy Proc. 12:187-191 (1991). |
|
|
| |
|
|
|
| C1878 |
Cetrimide |
50 g |
$37.30 |
| |
Hexadecyltrimethylammonium bromide |
250 g |
$131.20 |
| |
C19H42BrN FW 364.45 [57-09-0] |
|
|
| |
A mixture of chiefly tetradecyltrimethylammonium bromide together with smaller |
|
|
| |
amounts of dodecyltrimethylammonium bromide and cetrimonium bromide. |
|
|
| |
|
|
|
| C1879 |
Cetrorelix Acetate |
Please inquire |
|
| |
C70H92N17O14 FW 1431.06 [130143-01-0] |
|
|
| |
Injectable cetrorelix acetate is a synthetic decapeptide with gonadotropin-releasing hormone |
|
|
| |
(GnRH) antagonistic activity. Cetrorelix acetate is an analogue of native GnRH with substitutions |
|
|
| |
of amino acids at positions 1, 2, 3, 6, and 10. |
|
|
| |
|
|
|
| C2468 |
b-CGRP, human |
1 mg |
$401.40 |
| |
C162H267N51O48S3 Mol Wt: 3793.38 |
|
|
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C2800 |
Chalcone 97% |
25 g |
$23.30 |
| |
trans-Benzylideneacetophenone |
100 g |
$55.70 |
| |
C15H12O FW 208.26 m.p. 550C [614-47-1] |
500 g |
$194.80 |
| |
An open chain flavonoid. Inhibits lung and forestomach carcinogenesis. |
|
|
| |
Wattenberg, LW, Coccia, JB, Galbraith, AR. Cancer Lett. 83:165-169 (1994). |
|
|
| |
|
|
|
| C2803 |
Chartreusin |
5 mg |
$91.40 |
| |
Lambdamycin |
25 mg |
$368.80 |
| |
C32H32O14 FW 640.6 [6377-18-0] |
|
|
| |
An antitumor antibiotic from Streptomyces chartreusis. It inhibits topoisomerase II and |
|
|
| |
has been shown to inhibit DNA and RNA synthesis in certain models. |
|
|
| |
Obrig T, Frenkel GD. Res Commun Chem Path. 34:173-6 (1981). |
|
|
| |
Lorico A, Long BH. Eur J Cancer. 29A:1985-91 (1993). |
|
|
| |
|
|
|
| C2816 |
Cheirolin, 98% |
25 mg |
$96.10 |
| |
C5H9NO2S2 FW 179.26 [505-34-0] |
50 mg |
$160.30 |
| |
|
100 mg |
$288.30 |
| |
|
500 mg |
$971.40 |
| |
|
|
|
| C2818 |
Chelerythrine Chloride |
1 mg |
$39.50 |
| |
C21H18ClNO4 FW 383.82 [3895-32-9] |
5 mg |
$144.30 |
| |
A natural benzophenanthridine alkaloid. Inhibits protein kinase C and induces |
|
|
| |
apoptosis in HL-60 human promyelocytic leukemia cells. |
|
|
| |
Jarvis WD, Turner AJ, Povirk LF. Cancer Res. 54:1707-14 (1994). |
|
|
| |
Anthony ML, Zhao M, Brindle KM. J Biol Chem. 274:19686-92 (1999). |
|
|
| |
|
|
|
| C2916 |
Chenodeoxycholic Acid |
1 g |
$26.00 |
| |
C24H40O4 FW 392.57 [474-25-9] |
5 g |
$77.60 |
| |
Bile acid that induces apoptosis via a protein kinase C-dependent signaling |
25 g |
$258.20 |
| |
pathway. |
|
|
| |
Matinez, J.D., Stratagoules, E.D., LaRue, J.M., et al. Nutr. Cancer 31:111-8 (1998). |
|
|
| |
|
|
|
| C2946 |
Chlorambucil |
100 mg |
$14.80 |
| |
C14H19Cl2NO2 FW 304.21 [305-03-3] |
500 mg |
$30.20 |
| |
A nitrogen mustard alkylating agent commonly used to treat lymphocytic |
1 g |
$42.80 |
| |
leukemia. It induces apoptosis in chronic lymphocytic leukemia cells. |
10 g |
$382.00 |
| |
Begleiter A, Mowat M, Israels LG, Johnston JB. Leuk Lymphoma. 23:187-201 (1996). |
|
|
| |
King D, Pringle JH, Hutchinson M, Cohen GM. Leukemia. 12:1553-60 (1998). |
|
|
| |
|
|
|
| C2844 |
Chloramphenicol |
5 g |
$26.10 |
| |
C11H12Cl2N2O5 FW 323.13 m.p. 150.5-151.50C [56-75-7] |
10 g |
$44.90 |
| |
A broad spectrum antibiotic. It induces apoptosis in the developing brain. |
50 g |
$111.20 |
| |
Guimaraes CA, Linden R. Neuropharmacology. 39:1673-9 (2000). |
|
|
| |
C11H12Cl2N2O5 F.W. 323.13, m.p. 150.5-151.50C [56-75-7] |
|
|
| |
|
|
|
| |
|
|
|
| C2845 |
Chloramphenicol Levo |
5 g |
$27.70 |
| |
C11H12Cl2N2O5 FW 323.13 m.p. 150.5-151.50C [56-75-7] |
10 g |
$47.70 |
| |
Optically active chloramphenicol. |
50 g |
$112.90 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C2847 |
Chlormadinone Acetate |
1 g |
$112.10 |
| |
C23H29ClO4 FW 404.93 |
5 g |
$504.40 |
| |
Progestogen with questionable antiandrogenic activity. It suppresses ACTH |
|
|
| |
hypersecretion and lowers plasma testosterone levels. |
|
|
| |
Kageyama Y, Kitahara S, Tsukamoto T et al. Endocr J. 42:505-8 (1995). |
|
|
| |
Labrie F, DuPont A, Belanger A et al. Cancer Metastasis Rev. 6:615-36 (1987). |
|
|
| |
|
|
|
| C2942 |
Chlormethine HCl |
5 g |
$72.80 |
| |
Mechlorethamine HCl |
10 g |
$128.80 |
| |
C5H11Cl2N.ClH FW 192.51 [55-86-7] |
25 g |
$224.00 |
| |
A chemotherapeutic agent showing antitumor activity attributed to its ability to cross-link the |
|
|
| |
twin strands of DNA. A one-hour exposure caused a transient late S/G2 cell cycle arrest in |
|
|
| |
both the HL-60 cell line and the Colo 320HSR human colon cancer cell line. |
|
|
| |
Xie J, Shults K, Flye L et al. J Cell Biochem. 95:339-351 (2005). |
|
|
| |
Balcome S, Park S, Quirk Dorr DR et al. Chem Res Toxicol. 17:950-962 (2004). |
|
|
| |
|
|
|
| C2948 |
Chloroadenosine |
5 mg |
$25.30 |
| |
C10H12ClN5O4 FW 301.69 [146-77-0] |
10 mg |
$44.50 |
| |
Adenosine receptor site agonist that induces apoptosis. |
50 mg |
$127.30 |
| |
Szondy Z. Biochem J. 304:877-85 (1994). |
|
|
| |
|
|
|
| |
|
|
|
| C2944 |
Chlorogenic Acid |
100 mg |
$18.00 |
| |
C16H18O9 FW 354.31 m.p. 209-209oC (dec.) [327-97-9] |
250 mg |
$36.40 |
| |
A chemopreventive analogue of caffeic acid. |
1 g |
$102.00 |
| |
Tanaka T, Kojima T, Kawamori T et al. Carcinogenesis. 14:1321-1325 (1993). |
|
|
| |
|
|
|
| C2945 |
Chlorophyllin |
5 g |
$16.70 |
| |
Sodium-Copper Salt |
25 g |
$42.00 |
| |
[15611-43-5] |
100 g |
$146.30 |
| |
Sodium salt of copper complex have a water soluble salt of chlorophyll |
|
|
| |
which inhibits activation and degradation of electrophyllic intermediates. |
|
|
| |
Tachino H, Guo D, Dashwood WM et al. Mutat Res. 308:191-203 (1994). |
|
|
| |
|
|
|
| C2950 |
Chloroquine Phosphate |
25 g |
$34.50 |
| |
C18H26ClN3.2H3PO4 FW 515.87 [50-63-5] |
50 g |
$66.30 |
| |
Antimalarial agent that has been found to have a distinct affinity for melanin. |
100 g |
$96.70 |
| |
Used in the treatment of malaria, arthritis, and Lupus. |
|
|
| |
Graves PR, Kwiek JJ, Fadden P, Ray R et al. Mol Pharmacol. 62:1364-72 (2002). |
|
|
| |
Ono C, Yamada M, Tanaka M. J Pharm Pharmcol. 55:1647-54 (2003). |
|
|
| |
|
|
|
| C2949 |
Chlorpheniramine Maleate |
5 g |
$27.70 |
| |
C16H19ClN2.C4H4O4 FW 390.87 [113-92-8] |
25 g |
$41.40 |
| |
An antihistamine that has chemopreventive property. It inhibits carcinogen |
100 g |
$96.70 |
| |
aberrant crypt foci. Inhibits ornithine decarboxylase induction in experimental |
|
|
| |
mammary tumors and in MCF-7 cells. |
|
|
| |
Medina MA, Garcia de Veas R et al. Breast Cancer Res Treat. 35:187-94 (1995). |
|
|
| |
Wargovich MJ, Jimenez A, McKee K et al. Carcinogenesis. 21:1149-55 (2000). |
|
|
| |
|
|
|
| C2947 |
Chlorpromazine |
10 g |
$30.90 |
| |
2-Chloro-10-(3-dimethylaminopropyl)phenothiazine |
25 g |
$43.10 |
| |
C17H19Cl2N2S.HCl FW 355.3 [69-09-0] |
100 g |
$129.20 |
| |
A neuroleptic or antipsychotic drug used to reduce hallucinations and delusions in |
|
|
| |
persons with mental illness. It also has chemopreventive property. Chlorpromazine |
|
|
| |
increases protein synthesis and chromatin susceptibility to enzymatic degradation. |
|
|
| |
Lonacar-Stevanoic H et al. Journal of environmental Pathology, toxicology & Oncology. 17:331-7 (1998). |
|
|
| |
Peak MJ, Pafaff M, Peraino C. Br J Cancer. 60:220-2 (1989). |
|
|
| |
|
|
|
| C2951 |
Chlortetracycline Hydrochloride |
5 g |
$31.40 |
| |
C22H23ClN2O8.HCl FW 515.35 [64-72-2] |
25 g |
$87.80 |
| |
An antibiotic found to modulate TNF-alpha production. |
100 g |
$250.90 |
| |
Ball SJ, Warren EW. J Comp Pathol. 76:255-9 (1999). |
|
|
| |
Akunda JK, Johnson E, Ahrens FA et al. Comp Immunol Microb. 24:81-9 (2001). |
|
|
| |
|
|
|
| C2956 |
Cholecalciferol |
1 g |
$29.20 |
| |
Vitamin D3 |
5 g |
$130.00 |
| |
C27H44O FW 384.64 [67-97-0] |
25 g |
$370.00 |
| |
A form of vitamin D in fortified milk. Upon metabolic activation, induces cell differentiation and |
|
|
| |
prevents proliferation of cancer cells. Along with dietary calcium, reduces the risk of colon cancer. |
|
|
| |
Garland C, Garland FC. Int J Epidemiol. 9:227-231 (1980). |
|
|
| |
Mehta RG, Moriarty RM, Mehta RR et al. J Natl Cancer Inst. 89:212-218 (1997). |
|
|
| |
|
|
|
| C2957 |
Cholesterol |
5 g |
$25.10 |
| |
C27H46O FW 386.65 [57-88-5] |
25 g |
$37.60 |
| |
Major component of all biological membranes. It has been shown to inhibit |
100 g |
$119.20 |
| |
basal channel activity in the brain. |
|
|
| |
Crowley JJ, Treistman SN, Dopico AM. Mol Pharmacol. 64:365-72 (2003). |
|
|
| |
Peres C, Yart A, Perret B et al. FEBS Letters. 534:164-8 (2003). |
|
|
| |
|
|
|
| C2962 |
Cholinesterase Assay |
25 Tests |
$199.50 |
| |
Ph-F |
100 Tests |
$500.50 |
| |
|
|
|
| C2963 |
Cholinesterase and Apoptosis Assay |
25 Tests |
$237.10 |
| |
Ph-F and SR-VAD-FMK |
100 Tests |
$600.90 |
| |
|
|
|
| C2960 |
Chondroitin Sulfate |
5 g |
$30.50 |
| |
FW ~50,000 [9007-28-7] |
25 g |
$117.40 |
| |
A naturocetic agent. Effective against osteoarthritis. |
|
|
| |
Reginster JY, Bruyere O, Lecart MP, Henrotin Y. Curr Opin Rheumatol. 15:651-5 (2003). |
|
|
| |
Hungerford DS, Jones LC. J Arthroplasty. 8(3 Suppl 1):5-9 (2003). |
|
|
| |
Walker-Bone K. Drugs Aging. 20:517-26 (2003). |
|
|
| |
|
|
|
| C2965 |
Chromium Picolinate |
5 g |
$28.00 |
| |
C18H12CrN3O6 FW 418.3 [14639-25-9] |
25 g |
$72.80 |
| |
Used to treat chromium deficiency. There is concern that chromium picolinate |
|
|
| |
causes DNA damage and mutation. |
|
|
| |
Diaz, M. L. Journal of Nutritional Biochemistry (2008), 19(1), 61-68. |
|
|
| |
Hynes, A. M. J. Canadian Journal of Veterinary Research (2007), 71(4), 249-255. |
|
|
| |
|
|
|
| C2969 |
Chromomycin A3 |
1 mg |
$35.80 |
| |
C57H82O26 FW 1183.2488 [7059-24-7] |
5 mg |
$125.40 |
| |
The major component of a streptomycete contaminant in a marine fungal culture |
10 mg |
$224.00 |
| |
that is an aureolic acid derivative that is a minor groove DNA-binding antibiotic. |
|
|
| |
Skarbek JD, Brady LR. Lloydia. 38:369-377 (1975). |
|
|
| |
Marx C, Berger C, Xu F et al. Assay Drug Dev Technol. 4:273-284 (2006). |
|
|
| |
Marco E, Gago F. Mol Pharmacol. 68:1559-1567 (2005). |
|
|
| |
|
|
|
| C2971 |
Chromostatin, bovine |
0.5 mg |
$136.20 |
| |
C78H120N24O35 FW 1953.97 |
1 mg |
$231.20 |
| |
|
2.5 mg |
$408.60 |
| |
|
|
|
| C2968 |
Chrysin |
5 g |
$24.80 |
| |
C15H10O4 FW 254.2 [480-40-0] |
25 g |
$98.00 |
| |
A flavone which inhibits metabolic activation of benzo[a]pyrene. |
|
|
| |
Chae, Y-H., Ho, D.K., Cassady, J.M., et.al. Chem.-Biol. Int., 82:181-193 (1992). |
|
|
| |
|
|
|
| C2970 |
Chrysophanol |
10 mg |
$94.10 |
| |
1,8-Dihydroxy-3-methyl-9,10-anthracenedione, Chrysophanic acid |
25 mg |
$138.00 |
| |
C15H10O4 FW 254.24 [481-74-3] |
100 mg |
$439.00 |
| |
An anthraquinone found in the root of Rheum wittrochii. It has been shown to increase |
|
|
| |
intracellular Ca2+ concentration and exhibit antifungal activities. |
|
|
| |
Agarwal SK, Singh SS, Verma S et al. J Ethanopharmacol. 72:43-6 (2000). |
|
|
| |
Kagedal K, Bironaite D, Ollinger K. Free Radical Res. 31:419-28 (1999). |
|
|
| |
|
|
|
| C2997 |
Chymostatin |
1 mg |
$29.10 |
| |
N-[-Na-Carbonyl-Cpd-X-Phe-al]-Phe [9076-44-2] |
5 mg |
$87.40 |
| |
A highly specific chymotrypsin inhibitor produced by actinomycetes. It also |
25 mg |
$377.80 |
| |
has anticarcinogenic properties. It was found to suppress the incidence of |
50 mg |
$726.10 |
| |
squamous cell carcinomas of the anal gland. |
|
|
| |
Billings PC, Newberne PM, Kennedy AR. Carcinogenesis. 11:1083-6 (1990). |
|
|
| |
Billings PC, et. Al.,. Proc Natl Aca Sci. 84:4801-5 (1987). |
|
|
| |
|
|
|
| C3208 |
Ciclopirox Olamine |
1 g |
$33.60 |
| |
C12H17NO2.C2H7NO FW 268.355 [41621-49-2] |
5 g |
$112.00 |
| |
A substituted pyridone antimycotic with activity against a broad spectrum of dermatophytes, |
|
|
| |
yeasts, actinomycetes, molds, other fungi, and a variety of bacteria. |
|
|
| |
Jue SG, Dawson GW, Brogden RN. Drugs. 29:330-341 (1985). |
|
|
| |
|
|
|
| C3210 |
Ciglitazone |
1 mg |
$62.20 |
| |
C18H23NO3S FW 333.45 [74772-77-3] |
5 mg |
$213.90 |
| |
An antidiabetic thiazolidinedione. A PPAR-gamma agonist. It induces apoptosis, inhibits COX-2. |
|
|
| |
It provides protection against cancers of the breast, lung, colon and prostrate. |
|
|
| |
Han S, Roman. J. Biochem Biophys Res Commun. 314:1093-9 (2004). |
|
|
| |
Ignatenko NA, Babbar N, Mehta D et al. Mol Carcinog. 39:91-102 (2004). |
|
|
| |
Mitsiades CS, Mitsiades N, Richardson PG et al. Semin Oncol. 30:309-12 (2003). |
|
|
| |
|
|
|
| C3446 |
Cilnidipine |
100 mg |
$84.00 |
| |
C27H28N2O7 FW 492.53 [132203-70-4] |
250 mg |
$140.00 |
| |
Excites and inhibits Calcium channels. Used as a potential hypertension drug. |
1 g |
$403.20 |
| |
Shima, E. American Journal of Hypertension (2008), 21(1), 78-84. |
|
|
| |
Sakata K. Drugs under experimental and clinical research (2003), 29(3), 117-23 |
|
|
| |
Fujii, S. Journal of Pharmacology and Experimental Therapeutics (1997), 280(3), 1184-1191 |
|
|
| |
|
|
|
| C3246 |
Cilostazol |
50 mg |
$110.40 |
| |
C20H27N5O2 FW 369.46 [73963-72-1] |
100 mg |
$172.50 |
| |
A selective inhibitor of phosphodiesterase-III with antiplatelet, antithrombotic |
500 mg |
$689.90 |
| |
and vasodilating properties. Cilostazol inhibits colon cancer cell motility and is |
|
|
| |
effective as an anti-metastasis drug. |
|
|
| |
Chapman TM, Goa KL. Am J Cardiovasc Drugs. 3:117-38 (2003). |
|
|
| |
Fareed J, Hoppensteadt DA, Bick RL. Clin Appl Thromb Hemost. 9:101-8 (2003). |
|
|
| |
Murata K et al. Clin Exp Metastasis.17:525-30 (1999). |
|
|
| |
Inada H, Shindo H, Tawata M, Onaya T. ife Sci. 65:1413-22 (1999). |
|
|
| |
|
|
|
| C3250 |
Cimetidine |
5 g |
$48.40 |
| |
C10H16N6S FW 252.34 [51481-61-9] |
10 g |
$62.20 |
| |
An immunomodulator. Suppresses the growth of several tumors, including |
25 g |
$135.30 |
| |
gastrointestinal cancer. An anti-angiogenic agent. Used in stage IV colorectal cancer. |
|
|
| |
Scheinfeld N. Dermatol Online J. 9:4 (2003). |
|
|
| |
Tomita K, Izumi K, Okabe S. J Pharmacol Sci. 93:321-30 (2003). |
|
|
| |
Yoshimatsu K et al. Gan To Kagaku Ryoho. 30:1794-7 (2003). |
|
|
| |
|
|
|
| C3251 |
Cinnarizine |
10 g |
$27.70 |
| |
|
100 g |
$200.70 |
| |
Calcium channel blocker. It is known to induce Parkinsonism. |
|
|
| |
Teive HA, Troiano AR, Germiniani FM et al. Parkinsonism Relat D. 10:243-5 (2004). |
|
|
| |
Terland O, Flatmark T. Neuropharmacology. 38:879-82 (1999). |
|
|
| |
Emanuel MB, Chamberlain JA, Whiting S et al. Brit J Clin Pharmaco. 7:189-95 (1979). |
|
|
| |
|
|
|
| C3260 |
Ciprofibrate |
25 mg |
$78.40 |
| |
C13H14Cl2O3 FW 289.157 [52214-84-3] |
100 mg |
$224.00 |
| |
A hypolipidemic compound that can induce proliferation of peroxisomes in liver cells of |
|
|
| |
rats. Rat tumor liver cell line 7777 underwent apoptosis in vivo. |
|
|
| |
Lalwani ND, Reddy MK, Qureshi SA et al. Hum Toxicol. 2:27-48 (1983). |
|
|
| |
Clemencet MC, Muzio G, Trombetta A et al. Cancer Lett. 222:217-226 (2005). |
|
|
| |
|
|
|
| C3262 |
Ciprofloxacin (See page 15 for more information) |
5 g |
$26.00 |
| |
C17H18FN3O3 F.W 331.35 |
25 g |
$68.90 |
| |
It has activity against anaerobic bacteria in vitro and is used in postexposure |
50 g |
$103.30 |
| |
prophylaxis against inhalation anthrax. |
|
|
| |
Watt B, Brown FV, Jantimicrob. Chemother. 17:605. (1986). |
|
|
| |
Friedlandeder, A.M., Welkos, S.L. Pitt, M.L., et al J Infect Diseases 167:1239-43 (1993). |
|
|
| |
|
|
|
| C3263 |
Ciprofloxacin Hydrochloride |
5 g |
$22.60 |
| |
C17H18FN3.HCl.H2O FW 385.82 [86393-35-0] |
25 g |
$62.70 |
| |
|
50 g |
$106.60 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C3374 |
Cisplatin |
50 mg |
$39.90 |
| |
cis-Platinum(II)diammine dichloride |
100 mg |
$62.90 |
| |
Cl2H6N2Pt FW 300.04 m.p. 270oC (dec.) [15663-27-1] |
500 mg |
$223.70 |
| |
A platinum coordination complex with antitumor activity. |
|
|
| |
Tomson, A.J. Rec. Res. Cancer Res. 48: 38 (1974). |
|
|
| |
|
|
|
| C3477 |
Citalopram Hydrobromide |
25 mg |
$56.40 |
| |
C20H21FN2O.HBr FW 405.31 [59729-32-7] |
100 mg |
$181.90 |
| |
A selective serotonin reuptake inhibitor and antidepressant. It has shown |
500 mg |
$564.50 |
| |
evidence of being effective at reducing aberrant motor behaviors in Alzheimer disease. |
|
|
| |
Pousti A, Deemyad T, Malihi G. Hum Psychopharm. 19:347-50 (2004). |
|
|
| |
|
|
|
| C3479 |
Citrinin |
1 mg |
$28.00 |
| |
C13H14O5 Mol. Wt.: 250.249 [518-75-2] |
5 mg |
$87.40 |
| |
A mycotoxin produced by Penicillum citrinum that has been shown to result in |
10 mg |
$162.40 |
| |
enlarged kidneys and livers in young broiler chicks. |
|
|
| |
Ames DD, Wyatt RD, Marks HL, Washburn KW. Poult Sci. 55:1294-1301 (1976). |
|
|
| |
|
|
|
| C3578 |
L-Citrulline |
1 g |
$20.20 |
| |
C6H12N3O3 FW 175.19 [372-75-8] |
5 g |
$25.20 |
| |
An amino acid first isolated from watermelon. |
25 g |
$72.80 |
| |
Schwedhelm, E, British Journal of Clinical Pharmacology (2008), 65(1), 51-59. |
100 g |
$224.00 |
| |
|
|
|
| C4274 |
CKS-17 |
0.5 mg |
$64.50 |
| |
C87H148N26O24 FW 1942.31 |
1 mg |
$109.30 |
| |
17-amino acid peptide which is highly immunosuppressive. CKS-17 has also |
2.5 mg |
$193.50 |
| |
been shown to induce cyclic adenosine monophosphate in vitro. |
|
|
| |
Haraguchi, S.; Good, R. A.; Cianciolo, G. J.; Engelman, R. W.; Day, N. K. J. Leukoc. Biol. 61:654-66 (1997). |
|
|
| |
|
|
|
| C4402 |
Cladribine |
5 mg |
$69.40 |
| |
C10H12ClN5O3 FW 285.69 [4291-63-8] |
10 mg |
$109.80 |
| |
A nucleoside analogue that was found to induce DNA double-strand breaks and cell |
25 mg |
$246.40 |
| |
death in log-phase Chinese hamster V79 cells. |
|
|
| |
Tanabe K, Hiraoka W, Kuwabara M et al. Chem Biol Interact. 71:167-175 (1989). |
|
|
| |
|
|
|
| |
|
|
|
| C4502 |
Clarithromycin |
100 mg |
$48.40 |
| |
C38H69NO13 FW 747.95 [81103-11-9] |
250 mg |
$86.10 |
| |
A macrolide antibiotic. |
1 g |
$258.20 |
| |
Hardy, D.J., Guay, D.R., Jones, R.N Diagn Microbiol Infect Dis. 15:38-53 (1992). |
|
|
| |
|
|
|
| |
|
|
|
| C4517 |
Clenbuterol Hydrochloride |
25 mg |
$39.20 |
| |
C12H18Cl2N2O.HCl FW 313.65 [21898-19-1] |
100 mg |
$112.00 |
| |
A beta 2 agonist that may potentiate hypoxemia as a result of increased shunt |
250 mg |
$168.00 |
| |
fraction in horses anesthetized by the IV route. This beta 2 agonist has also been shown |
|
|
| |
to enhance memory in sham-lesioned male Sprague Dawley rats. |
|
|
| |
Dodam JR, Moon RE, Olson NC et al. Am J Vet Res. 54:776-782 (1993). |
|
|
| |
Introini-Collison IB, Miyazaki B, McGaugh JL. Psychopharmacology (Berl). 104:541-544 (1991). |
|
|
| |
|
|
|
| C4510 |
Climbazole |
5 g |
$48.40 |
| |
C15H17ClN2O2 FW 292.76 [38083-17-9] |
10 g |
$66.30 |
| |
A potent inducer and inhibitor of P450-dependent drug metabolizing enzymes, |
25 g |
$138.00 |
| |
which is also used as antifungal and antidandruff agent. |
|
|
| |
Mayser P, Argembeaux H, Rippke F. J Cosmet Sci. 54:263-70 (2003). |
|
|
| |
Kobayashi Y et al. Biol Pharm Bull. 25:53-7 (2002). |
|
|
| |
|
|
|
| C4535 |
Clinafloxacin Hydrochloride |
100 mg |
$95.20 |
| |
C17H17ClFN3O3.HCl FW 402.24 [105956-99-8] |
250 mg |
$196.00 |
| |
Antimicrobial fluoroquinolone inhibits topoisomerase IV. |
1 g |
$448.00 |
| |
Pan, X.S., Fisher, L.M. Antimicrob Agents Chemother. 43:1129-36 (1999). |
|
|
| |
|
|
|
| C4532 |
Clindamycin Hydrochloride |
10 mg |
$45.70 |
| |
C18H34Cl2N2O5S FW 461.44 m.p. 141-1430C [21462-39-5] |
50 mg |
$164.80 |
| |
An effective antibacterial agent against gram-positive bacteria. Clindamycin HCl |
100 mg |
$295.50 |
| |
attaches to the 50S subunit of bacterial ribosomes and suppresses protein synthesis. |
|
|
| |
Reusser, F. Antimicrobial Agents Chemother. 7: 32 (1975). |
|
|
| |
|
|
|
| C4534 |
Clindamycin Palmitate HCl |
10 mg |
$44.90 |
| |
C34H63ClN2O6S FW 663.39 |
50 mg |
$163.70 |
| |
Inactive molecule which is hydrolyzed into its active form by |
100 mg |
$301.40 |
| |
small-intestine enzymes. |
|
|
| |
Cimbollek, M., Nies, B., Liebendorfer, A., Wenz, R. J. Controlled Release 33:47-53 (1995). |
|
|
| |
|
|
|
| C4533 |
Clindamycin Phosphate |
10 mg |
$40.40 |
| |
C18H34ClN2O8PS FW 504.96 [24729-96-2] |
50 mg |
$134.40 |
| |
The 2-dihydrogen phosphate analog of Clindamycin. |
100 mg |
$236.40 |
| |
|
|
|
| |
|
|
|
| C4659 |
Clobetasol Propionate |
100 mg |
$34.50 |
| |
C25H32ClFO5 FW 466.98 [25122-46-7] |
500 mg |
$124.20 |
| |
An anti-inflammatory, antipruritic and vasoconstrictive agent. Shown to be |
1 g |
$227.70 |
| |
effective against tufted angioma. |
|
|
| |
Melian EB, Spencer CM, Jarvis B. Am J Clin Dermatol. 2:89-92; discussion 93 (2001). |
|
|
| |
Bernstein EF, Kantor G, Howe N et al. J Am Acad Dermatol. 31:307-11 (1994). |
|
|
| |
|
|
|
| C3449 |
Clodronate Disodium |
10 mg |
$37.50 |
| |
CH2Cl2Na2O6P2.4H2O FW 360.925 [88416-50-6] |
50 mg |
$152.20 |
| |
A bisphosphonate bone resorption inhibitor. |
100 mg |
$275.40 |
| |
Plosker, G.L., Goa, K.L. Drugs 47:945-82 (1994). |
|
|
| |
|
|
|
| C4646 |
Clofarabine |
10 mg |
$112.00 |
| |
C10H11CLFN5O3 FW 303.68 [123318-82-1] |
25 mg |
$224.00 |
| |
A purine nucleoside anti-metabolite which is used in the treatment of acute |
100 mg |
$728.00 |
| |
lymphoblastic leukemia. |
|
|
| |
Steinherz, P. G. Journal of Pediatric Hematology/Oncology (2007), 29(9), 656-658 |
|
|
| |
Krynetskaia, N. Molecular Pharmacology (2008), 73(1), 260-269. |
|
|
| |
Faderl, S. Blood (2008), 112(5), 1638-1645. |
|
|
| |
|
|
|
| C4557 |
Clofibrate |
1 g |
$43.10 |
| |
2-(4-Chlorophenoxy)-2-methylpropionic acid ethyl ester |
5 g |
$137.80 |
| |
C12H15ClO3 FW 242.470 [637-07-0] |
|
|
| |
A peroxisome proliferator and hypolipidemic drug. Induces apoptosis in hepatoma cells. |
|
|
| |
Also a liver tumor promoter. |
|
|
| |
Canuto, R.A.,, Muzio, G., Bonelli, G., et al. Cancer Detect Prev. 22:357-66 (1998). |
|
|
| |
Adinehzadeh, M., Reo, N.V. Chem Res Toxicol 11:428-40 (1998). |
|
|
| |
|
|
|
| C4556 |
Clofibric acid |
10 g |
$20.70 |
| |
C10H11ClO3 FW 214.65 [882-09-7] |
50 g |
$32.90 |
| |
A drug used to reduce cholesterol levels in the blood. |
|
|
| |
|
|
|
| C4559 |
Clomiphene Citrate |
1 g |
$27.70 |
| |
Clomifene citrate |
5 g |
$75.90 |
| |
C26H28ClNO.ClNO.C6H8O7 FW 598.09 [50-41-9] |
10 g |
$124.20 |
| |
A selective estrogen receptor modulator. It is used as an antileukemic drug which kills cells |
|
|
| |
by apoptosis mediated by oxidative stress and activation of PKC. |
|
|
| |
Haskell SG. South Med J. 96:469-76 (2003). |
|
|
| |
Hayon T, Dvilansky A, Oriev L, Nathan I. Anticancer Res. 19:2089-93 (1999). |
|
|
| |
|
|
|
| C4558 |
Clonidine HCl |
250 mg |
$48.00 |
| |
C9H10ClN3 FW 266.55 [4205-91-8] |
1 g |
$154.00 |
| |
is a direct-acting _2 adrenergic agonist prescribed historically as an antihypertensive agent. |
|
|
| |
Pettibone, Douglas J., Brain Research (1981), 221(2), 409-14. |
|
|
| |
|
|
|
| C4658 |
Clopidogrel Sulfate |
500 mg |
$69.00 |
| |
C16H16ClNO2S.H2SO4 FW 419.90 [135046-48-9] |
1 g |
$117.40 |
| |
An ADP receptor antagonist that inhibits platelet aggregation. |
5 g |
$517.40 |
| |
Lecompte T. Arch Mal Coeur Vaiss. 94:1225-32 (2001). |
|
|
| |
Reist M et al. Drug Metab Dispos. 28:1405-10 (2000). |
|
|
| |
|
|
|
| C4656 |
Clopidol |
1 g |
$38.10 |
| |
C7H7Cl2NO FW 192.04 [2971-90-6] |
5 g |
$83.60 |
| |
An antiplatelet drug. |
25 g |
$379.50 |
| |
Izaguirre-Avila R et al. Clin Appl Thromb Hemost. 8:169-77 (2002). |
|
|
| |
|
|
|
| C4758 |
Closantel Sodium |
1 g |
$34.50 |
| |
C22H14Cl2I2N2O2 FW 686.1 [61438-64-0] |
5 g |
$62.20 |
| |
A potent anthelmintic agent that is also used in combination with levamisole to |
25 g |
$227.70 |
| |
control gastrointestinal infection in sheep. |
|
|
| |
Swan GE. J S Afr Vet Assoc. 70:61-70 (1999). |
|
|
| |
Maingi N, Munyua WK, Gichigi MN. Acta Trop. 84:93-100 (2002). |
|
|
| |
|
|
|
| C4657 |
Clotrimazole |
5 g |
$51.60 |
| |
C22H17ClN2 FW 344.84 [23593-75-1] |
10 g |
$86.10 |
| |
An antifungal imidazole, found to inhibit Ca (2+)-dependent K+ transport and cell |
25 g |
$172.10 |
| |
dehydration in sickel erythrocytes. |
|
|
| |
Brugnara, C., de Franceschi, L. Alper, S.L. J Clin Invest. 92:520-6 (1993). |
|
|
| |
|
|
|
| C4756 |
Cloxacillin sodium |
1 g |
$31.40 |
| |
C19H18ClN3NaO5S.H2O FW 475.55 [7081-44-9] |
5 g |
$87.80 |
| |
A semi-synthetic antibiotic related to penicillin. |
25 g |
$250.90 |
| |
Mattie H, Zhang LC, van Strijen E et al. Antimicrob Agents Ch. 41:2083-8 (1997). |
|
|
| |
Dan M, Asherov J, Poch F. Diagn Micr Infec Dis. 33:39-42 (1999). |
|
|
| |
|
|
|
| C4757 |
Clozapine |
25 mg |
$50.20 |
| |
Clozaril, Leponex |
100 mg |
$169.30 |
| |
C18H19ClN4 FW 326.82 [5786-21-0] |
|
|
| |
Antipsychotic drug. It is effective in the treatment of levodopa-induced dyskinesias in severe |
|
|
| |
Parkinson's disease, and it increases both acetylcholine and dopamine release in rat ventral hippocampus. |
|
|
| |
Chung YC, Li Z, Dai J et al. Brain Res. 1023:54-63 (2004). |
|
|
| |
Durif F, Debilly B, Galitzky M et al. Neurology. 62:381-8 (2004). |
|
|
| |
|
|
|
| C4759 |
Clozapine N-oxide |
5 mg |
$78.40 |
| |
C18H19ClN4O FW 342.82 [34233-69-7] |
25 mg |
$308.00 |
| |
Is an antipsychotic medication used in the treatment of schizophrenia. It binds to |
|
|
| |
serotonergic and dopaminergic receptors and has a high affinity for the D4 receptor. |
|
|
| |
It has also been suggested that is is a partial agonist at the 5-HTIA receptor. |
|
|
| |
Also an agonist at the adrenergic, cholinergic and histaminergic receptors. |
|
|
| |
Martinez, V. Neuropsychopharmacology (2008), 33(11), 2635-2647. |
|
|
| |
Selent, J. ChemMedChem (2008), 3(8), 1194-1198. |
|
|
| |
|
|
|
| C5196 |
C-Myc Peptide |
1 mg |
$35.80 |
| |
C51H86N12O1 FW 1203.32 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| C5260 |
CNP-22, human, porcine, rat |
1 mg |
$210.80 |
| |
C93H157N27O28S3 Mol Wt: 2797.61 |
|
|
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C5645 |
Colchicine, 97 % |
500 mg |
$41.40 |
| |
C22H25NO6 FW 399.44 [64-86-8] |
1 g |
$66.30 |
| |
Microtubule disrupting agent that induces apoptosis in human lymphoma cells |
|
|
| |
and neuroblastoma cells. |
|
|
| |
Takano, Y., Okudaira, M., Harmon, B.V. Pathol Res Pract. 189:197-203 (1993). |
|
|
| |
Nakagawa-Yagi, Y. Biochem Biophys Res Commun. 199:807-17 (1994). |
|
|
| |
|
|
|
| C5647 |
Colistin sulphate |
100 mg |
$27.70 |
| |
[1264-72-8] |
500 mg |
$103.50 |
| |
A cationic polypeptide antibiotic from the polymyxin family. It is effective in |
1 g |
$138.00 |
| |
the management of Pseudomonas aeruginosa infections in patients with |
5 g |
$441.60 |
| |
cystic fibrosis. |
|
|
| |
Beringer P. Curr Opin Pulm Med. 7:434-40 (2001). |
|
|
| |
Evans ME, Feola DJ, Rapp RP. Ann Pharmacother. 33:960-7 (1999). |
|
|
| |
|
|
|
| C5646 |
Collagen Binding Fragment |
1 mg |
$64.50 |
| |
C52H75N14O20S FW 1248.32 |
2 mg |
$109.30 |
| |
|
5 mg |
$193.50 |
| |
|
|
|
| C5654 |
Concanavalin A |
50 mg |
$30.10 |
| |
[11028-71-0] |
250 mg |
$106.60 |
| |
A plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts. |
500 mg |
$174.40 |
| |
Nagase, F., Abo, T., Hiramatsu, K., et al. Microbiol Immunol. 42:567-74 (1998). |
1 g |
$264.30 |
| |
Kulkarni, G.V., Lee, W., Seth, A., McCulloch, C.A., Exp Cell Res. 245:170-8 (1998). |
|
|
| |
|
|
|
| C5655 |
a-Conotoxin GI |
0.5 mg |
$78.80 |
| |
C55H76N20O18S4 FW 1433.63 |
1 mg |
$134.40 |
| |
Causes postsynaptic inhibition at the neuromuscular junction. |
2.5 mg |
$236.50 |
| |
Gray, W. R.; Luque, A.; Olivera, B. M.; Barrett, J.; Cruz, L. J. J. Biol. Chem. 256:4734, (1981). |
|
|
| |
|
|
|
| C5656 |
a-Conotoxin IMI |
0.5 mg |
$78.80 |
| |
C52H74N20O15S4 FW 1347.58 |
1 mg |
$134.40 |
| |
|
2.5 mg |
$236.50 |
| |
|
|
|
| C5662 |
Copper bis-3,5-diisopropylsalicylate |
1 g |
$43.10 |
| |
C26H34O6Cu FW 506.11 |
5 g |
$129.20 |
| |
A superoxide dimutase compound that inhibits protein kinase C in rat liver and reduces the |
|
|
| |
activity of TPA stimulated protein kinase C. It is shown that a pretreatment of normal |
|
|
| |
golblet cells of the colonic mucosa by this material sensitizes them to apoptosis induced |
|
|
| |
by sodium deoxycholate (bile salt). |
|
|
| |
Nilsson K, Cancer Lett. 47: 169-77 (1989). |
|
|
| |
Washo-Stultz D, Holgen N, Bernstein H, Bernstein C, Payne CM. Nutr Cancer. 35:180-8 (1999). |
|
|
| |
|
|
|
| C5768 |
Corazonin |
1 mg |
$50.20 |
| |
C62H86N18O19 FW 1369.46 [122984-73-0] |
2 mg |
$86.00 |
| |
A potent cardioactive peptide isolated from a variety of insects. |
5 mg |
$150.50 |
| |
Predel R, Neupert S, Russell WK, Scheibner O, Nachman RJ. Peptides. 28: 3-10 (2006). |
|
|
| |
|
|
|
| C5771 |
Corticosterone |
100 mg |
$19.30 |
| |
C21H30O4 FW 346.46 [50-22-6] |
250 mg |
$37.00 |
| |
Elevation of plasma corticosterone level induces apoptosis |
500 mg |
$66.20 |
| |
in murine bone marrow. |
|
|
| |
Garvy, B.A., King, L.E., Telford, W.G., et al. Immunology. 80:587-92 (1993). |
|
|
| |
|
|
|
| C5770 |
Corticotropin Releasing Factor, bovine |
0.5 mg |
$179.20 |
| |
C206H340N60O63S FW 4697.44 |
1 mg |
$304.60 |
| |
It is a neurotransmitter which also releases ACTH and endorphin from the anterior |
2.5 mg |
$537.60 |
| |
pituitary. |
|
|
| |
Eckart, K., et al. Curr. Med. Chem. 6:1035-1053 (1999). |
|
|
| |
|
|
|
| C5772 |
Corticotropin Releasing Factor, human, rat |
0.5 mg |
$179.20 |
| |
CRF |
1 mg |
$304.60 |
| |
C208H344N60O63S2 FW 4757.49 [86784-80-7] |
2.5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C5774 |
Corticotropin Releasing Factor, ovine |
0.5 mg |
$179.20 |
| |
C205H339N59O63S FW 4370.41 |
1 mg |
$304.60 |
| |
|
2.5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C5773 |
Cortistatin 14, (rat) |
0.5 mg |
$215.00 |
| |
C81H113N19O19S2 FW 1721.02 |
1 mg |
$365.60 |
| |
A neuropeptide that binds all SS receptor subtypes and ghrelin's receptors. |
2.5 mg |
$645.10 |
| |
It has been found to inhibit cell proliferation of human thyroid carcinoma cell lines. |
|
|
| |
Broglio F, Arvat E, Benso A et al. J Clin Endocrinol Metab. 87:3783-90 (2002). |
|
|
| |
Cassoni P, Muccioli G, Marrocco T et al. J Endocrinol Invest. 25:362-8 (2002). |
|
|
| |
|
|
|
| C5782 |
Coumarin |
10 g |
$20.70 |
| |
2H-1-Benzopyan-2-one |
50 g |
$34.50 |
| |
C9H6O2 FW 146.14 [91-64-5] |
|
|
| |
An anticoagulant found in medicinal plants and used in phytomedicine for the treatment of venous |
|
|
| |
diseases. It is found to have anti-tumor activities in several human cells lines. |
|
|
| |
Weber US, Steffen B, Siegers CP. Res Commun Mol Pathol Pharmacol. 99:193-206 (1998). |
|
|
| |
Pineo G, Hull RD. Hematol Oncol Clin North Am. 17:201-16 (2003). |
|
|
| |
|
|
|
| C5680 |
Coumestrol |
10 mg |
$169.10 |
| |
C15H8O5 FW 268.2 [479-13-0] |
25 mg |
$338.10 |
| |
A plant estrogen and highly potent inhibitor of 17-b-hydroxysteroid oxidoreductase. |
|
|
| |
Poutanen, M., Lehtimaki, J., Kostian, M.L., Santti, R., Vihko, R. Proc.Soc.Exp.Biol.Med. 208:51-59 (1995). |
|
|
| |
|
|
|
| C6018 |
C-Peptide, dogs |
0.5 mg |
$179.20 |
| |
C137H225N37O49 FW 3174.54 |
1 mg |
$304.60 |
| |
|
2.5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| C6019 |
C-Peptide, human |
0.5 mg |
$179.20 |
| |
C129H211N35O48 FW 3020.33 |
1 mg |
$304.60 |
| |
|
2.5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| C6916 |
CREBtide |
1 mg |
$164.90 |
| |
C73H127N29O18 FW 1699.01 |
2 mg |
$279.60 |
| |
|
5 mg |
$494.60 |
| |
|
|
|
| C6955 |
Cromolyn sodium |
1 g |
$43.10 |
| |
C23H14Na2O11 FW 512.3 [15826-37-6 |
5 g |
$129.20 |
| |
A chemopreventive and anti-inflammatory agent. In rats, it was found that |
|
|
| |
application of cromolyn sodium prior to benzo[a]pyrene administration prevents tumor |
|
|
| |
formation and provokes a significant inhibition of the carcinogenic process. |
|
|
| |
Matsuo N, Shinoda T, Matsuse H, Obase Y, Asai S, Kohno S. Ann allergy Asthma Immunol. 84:72-8 (2000). |
|
|
| |
Vickova A, Horakova K, Sloboda J, Ulrich L, Babinska M, Babulova A. Carcinogenesis. 7:371-4 (1986). |
|
|
| |
|
|
|
| C6956 |
Crotamiton |
25 g |
$69.00 |
| |
C13H17NO FW 203.28 [483-63-6] |
100 g |
$248.40 |
| |
Used in the treatment of scabies, crotamiton with phototherapy. Effective against pruritus of breast |
|
|
| |
carcinoma skin infiltration. |
|
|
| |
Buffet M, Dupin N. Fundam Clin Pharmacol. 17:217-25 (2003). |
|
|
| |
Holme SA, Mills CM. J Pain Symptom Manage. 22:803-5 (2001). |
|
|
| |
|
|
|
| C6957 |
Croton Oil |
100 g |
$152.20 |
| |
[8001-28-3] |
1 kg |
$680.10 |
| |
A natural source of phorbol and phorbol esters. |
|
|
| |
|
|
|
| |
Crotalus durissus terrificus (See snake venom) |
|
|
| |
|
|
|
| C6982 |
Crustacean Cardioactive Peptide, CCAP |
1 mg |
$64.50 |
| |
C42H56N10O12S2 FW 957.1 |
2 mg |
$109.30 |
| |
|
5 mg |
$193.50 |
| |
|
|
|
| C7097 |
Cryptotanshinone |
10 mg |
$118.50 |
| |
C19H20O3 FW 296.36 |
25 mg |
$250.50 |
| |
A quinoid diterpene isolated from the root of the Chinese medicinal plant Salvia |
100 mg |
$801.50 |
| |
miotiorrhiza bunge. It has antibacterial and antimutagenic activities. Its antibacterial |
|
|
| |
activity was attributed to its ability to generate superoxide radicals. |
|
|
| |
Pan, X., Niu, G., Liu, H. J. Chromatography A. 922:371-375 (2001). |
|
|
| |
Lee, D.S., Lee, S.H., Noh, J.G., Hong, S.D. Biosci Biotech Biochem. 63:2236-2239 (1999). |
|
|
| |
|
|
|
| C7098 |
Crystalline |
1 mg |
$13.40 |
| |
C12H15N3O3 FW 261.2 |
2 mg |
$22.40 |
| |
|
5 mg |
$40.30 |
| |
|
|
|
| C7602 |
CTAP |
0.5 mg |
$78.80 |
| |
C51H67N13O11S FW 1102.33 |
1 mg |
$134.40 |
| |
�-selective opioid receptor antagonist. |
2.5 mg |
$236.50 |
| |
Abbruscato, T. J.; Thomas, S. A.; Hruby, V. J.; Davis, T. P. J. Pharmacol. Exp. Ther. 280:402 (1997). |
|
|
| |
|
|
|
| C7618 |
C-telopeptide |
0.5 mg |
$64.50 |
| |
C34H56N14O13 FW 868.91 |
1 mg |
$109.30 |
| |
|
2.5 mg |
$193.50 |
| |
|
|
|
| C7692 |
CTX IV (6-12) |
1 mg |
$62.70 |
| |
C48H70N10O7 FW 899.14 |
2 mg |
$107.50 |
| |
|
5 mg |
$188.20 |
| |
|
|
|
| C7693 |
[Arg3,14] CTX IV (3-14) |
1 mg |
$98.60 |
| |
C74C119N25O14 FW 1582.91 |
2 mg |
$168.40 |
| |
|
5 mg |
$295.70 |
| |
|
|
|
| C7997 |
C-Type Natriuretic Peptide (1-22), human |
0.5 mg |
$129.00 |
| |
C93H157N27O28S3 FW 2197.64 |
1 mg |
$218.60 |
| |
C-type natriuretic peptide (CNP) is a peptide produced by the vascular |
2.5 mg |
$387.10 |
| |
endothelium with vasodilative properties. CNP was found to play an important role |
|
|
| |
in linear growth and is believed to be an endothelium-derived hyperpolarizing factor. |
|
|
| |
Sandow, S. L.; Tare, M. Trends Pharmacol. Sci. 28:61-7 (2007). |
|
|
| |
Olney, R. C. Growth Horm. IGF Res. A:S6-14 (2006). |
|
|
| |
|
|
|
| C7998 |
C-Type Natriuretic Peptide, chicken |
0.5 mg |
$121.90 |
| |
C93H157N29O29S3 FW 2241.66 |
1 mg |
$207.90 |
| |
|
2.5 mg |
$365.60 |
| |
|
|
|
| |
|
|
|
| C8017 |
Cuelure |
100 mg |
$43.90 |
| |
4-(3-Oxobutyl)phenyl acetate |
250 mg |
$81.50 |
| |
C12H14O3 FW 206.24 [3572-06-3] |
1 g |
$210.80 |
| |
An insect sex hormone used to interrupt the mating of melon flies. |
|
|
| |
|
|
|
| C8069 |
Curcumin |
5 g |
$23.40 |
| |
C21H20O6 FW 368.38 m.p. 1830C [458-37-7] |
10 g |
$41.00 |
| |
An antipromoter with antioxidant and anti-inflammatory |
50 g |
$163.70 |
| |
activities. Inhibits lipoxygenase and cyclooxygenase. |
|
|
| |
Huang, M-T., Lysz, T., Ferraro, T et al. Cancer Res., 51:813-819 (1991). |
|
|
| |
|
|
|
| C8500 |
CV-65 |
100 �g |
$188.20 |
| |
C13H7N2O4 FW 270.24 |
1 mg |
$1,003.50 |
| |
Diaza-anthracene compound known to inhibit ERK and JNK kinases. |
|
|
| |
Pipaon, C., Gutierrez, P., Montero, J.C., et al Mol.Cancer Ther. 10:811-819 (2002). |
|
|
| |
|
|
|
| C8501 |
CV-66 |
100 �g |
$188.20 |
| |
C14H10N2O4 FW 270.24 |
1 mg |
$1,003.50 |
| |
Diaza-anthracene compound known to inhibit ERK and JNK kinases. |
|
|
| |
Pipaon, C., Gutierrez, P., Montero, J.C., et al Mol.Cancer Ther. 10:811-819 (2002). |
|
|
| |
|
|
|
| C8502 |
CV-70 |
100 �g |
$188.20 |
| |
C16H14N2O4 FW 298.29 |
1 mg |
$1,003.50 |
| |
Diaza-anthracene compound known to inhibit ERK and JNK kinases. |
|
|
| |
Pipaon, C., Gutierrez, P., Montero, J.C., et al Mol.Cancer Ther. 10:811-819 (2002). |
|
|
| |
|
|
|
| C9677 |
Cyclocytidine hydrochloride |
1 g |
$51.60 |
| |
2,2'-Anhydro-1-b-D-arabinofuranosylcytosine hydrochloride |
5 g |
$216.90 |
| |
C9H11N3O4.HCl FW261.6 m.p. 269-2700C (dec.) [10212-25-6 |
|
|
| |
An antitumor agent. |
|
|
| |
Hoshi, A., Kanzawa, F., Kuretani, K. Gann., 63:353-360 (1972). |
|
|
| |
Ip, C., Ganther, H.E. Carcinogenesis 7:1167-1170 (1992). |
|
|
| |
|
|
|
| C9709 |
Cycloheximide, �96% |
1 g |
$60.40 |
| |
C15H23NO4 FW 281.35 [68-81-9] |
5 g |
$172.10 |
| |
A protein synthesis inhibitor. Induces apoptosis in tumor cell lines. |
|
|
| |
Collins, R.J., Harmon, B.V., Souvlis, T., et al. Br J Cancer. 64:518-22 (1991). |
|
|
| |
Gong, J., Li, X., Darzynkiewicz, Z. J Cell Physiol. 157:263-70 (1993). |
|
|
| |
Ishii, H.H., Etheridge, M.R., Gobe, G.C. Immunol Cell Biol. 73:463-8 (1995). |
|
|
| |
|
|
|
| C9710 |
Cyclopamine |
1 mg |
$120.50 |
| |
C27H41NO2 FW 411.62 [4449-51-8] |
5 mg |
$476.70 |
| |
A steroidal alkaloid isolated from the desert plant Veratrum californicum with both |
|
|
| |
teratogenic and antitumor activities. It inhibits hedgehog/smoothened signaling. |
|
|
| |
Coventry S, Kapur RP, Siebert JR. Pediatr Devel Pathol. 1:29-41 (1998).
|
|
|
| |
Chen JK, Taipale J, Cooper MK et al. Gene Dev. 16:2743-8 (2002). |
|
|
| |
Qualtrough D, Buda A, Gaffield W et al. Int J Cancer. 110:831-7 (2004). |
|
|
| |
|
|
|
| C9609 |
Cyclophosphamide monohydrate |
1 g |
$37.00 |
| |
C7H15Cl2N2O2P.H2O FW 279.10 m.p. 49-510C [6055-19-2] |
5 g |
$104.80 |
| |
An alkylating agent used in cancer therapy. Induces apoptosis in tumor cells and endothelial cells |
|
|
| |
within tumors. |
|
|
| |
Meyn, R.E., Stephens, L.C., Hunter, N.R., Milas, L. Cancer Chemother Pharmacol 33:410-4 (1994). |
|
|
| |
Browder, T., Butterfied\ld, C.E., ktaling, B.M. et al Cancer Res. 60:1878-86 (2000). |
|
|
| |
|
|
|
| C9809 |
Cyclopiazonic acid |
5 mg |
$58.20 |
| |
C20H20N2O3 Mol. Wt.: 336.389 [181172-33-3] |
10 mg |
$100.80 |
| |
An inhibitor of the sarco/endoplasmic reticulum calcium pump that has produced hypokinesia, |
|
|
| |
hypothermia, catalepsy, ptosis, and sedation without loss of righting reflex, tremor, gait disturbance, |
|
|
| |
dyspnoea, opisthotonus, atypical convulsion, and prolonged barbiturate-induced sleep in mice. |
|
|
| |
Nishie K, Cole RJ, Dorner JW. Food Chem Toxicol. 23:831-839 (1985). |
|
|
| |
Gover TD, Moreira TH, Kao JP, Weinreich D. Cell Calcium. 41:389-396 (2007). |
|
|
| |
|
|
|
| C9610 |
D-Cycloserine |
1 g |
$47.70 |
| |
C3H6N2O2 FW 102.09 [68-41-7] |
5 g |
$188.20 |
| |
A partial NMDA receptor allosteric agonist found to improve cognitive functions in humans. |
|
|
| |
Nitsche MA, Jaussi W, Liebetanz D et al. Neuropsychopharmacology. 29:1573-8 (2004). |
|
|
| |
Ogawa M, Shigeto H, Yamamoto T et al. J Neurol Sci. 210:53-6 (2003). |
|
|
| |
|
|
|
| C9611 |
Cyclosporin A |
10 mg |
$39.20 |
| |
C62H111N11O12 FW 1202.0 |
50 mg |
$84.00 |
| |
Immunosuppressive, nonpolar, cyclic oligopeptide. Inhibits the activity of |
100 mg |
$134.40 |
| |
transcription factors of NFAT cell family. Interferes with the induction of cytokines and other inducibles |
|
|
| |
immune response genes. Induces apoptosis and inhibits angiogenesis induced by VEGF. |
|
|
| |
Wiederrecht, G., Lam, E., Hung, S., et al. Ann N Y Acad Sci. 696:9-19 (1993). |
|
|
| |
Mongini, C., Waldner, C., Lopes, E.C. et al. Int. J Mol Med. 7:431-7 (2001). |
|
|
| |
Hernandez, G.L., Volpert, O.V., Iniguez, M.A. et al. J Exp Med. 193:607-20 (2001). |
|
|
| |
|
|
|
| C9615 |
Cyclosporin B |
1 mg |
$244.60 |
| |
C61H109N11O12 FW 1188.59 [63775-95-1] |
5 mg |
$978.40 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C9612 |
Cyclosporin C |
1 mg |
$68.40 |
| |
C62H111N11O13 FW 1218.61 [59787-61-0] |
5 mg |
$250.50 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C9613 |
Cyclosporin D |
1 mg |
$100.20 |
| |
C63H113N11O12 FW 1216.64 [63775-96-2] |
5 mg |
$372.00 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C9614 |
Cyclosporin H |
1 mg |
$100.20 |
| |
C62H111N11O12 FW 1202.61 [83602-39-5] |
5 mg |
$372.00 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| C9711 |
Cyclovirobuxine D |
25 mg |
$55.20 |
| |
|
100 mg |
$138.00 |
| |
An anti-atrial fibrillating agent. It induces release of endothelial nitric oxide. |
500 mg |
$545.10 |
| |
Wang YX, Zheng YM, Tan YH, Sheng BH. Yao Xue Xue Bao. 31:481-6 (1996). |
|
|
| |
Grossini E et al. Life Sci. 65:PL59-65 (1999). |
|
|
| |
|
|
|
| C9660 |
Cypermethrin |
10 mg |
$98.40 |
| |
C22H19Cl2NO3 FW 416.30 [52315-07-8] |
25 mg |
$196.90 |
| |
Synthetic pyrethroid insecticide that inhibits protein phosphatase. It was found |
100 mg |
$573.80 |
| |
to induce cytochrome P450 2B1 in primary rat hepatocyte cultures. |
|
|
| |
Enan, E., Matsumura, F. Biochem Pharmacol 43:1777-84 (1992). |
|
|
| |
Heder, A.F., Hirsch-Ernst, K.I., Bauer, D. et al Biochem Pharmacol 62:71-9 (2001). |
|
|
| |
|
|
|
| C9863 |
Cyproconazole |
5 g |
$39.20 |
| |
C15H18ClN3O FW 291.78 [9436-06-5] |
10 g |
$56.00 |
| |
Cyproconazole is a triazole fingicide which causes hepatocellular adenomas |
100 g |
$308.00 |
| |
and carcinomas. |
|
|
| |
Matsumura, M. Jpn. Kokai Tokkyo Koho (2007). |
|
|
| |
Mol, H. G. J. Analytical and Bioanalytical Chemistry (2007), 389(6), 1715-1754. |
|
|
| |
|
|
|
| C9662 |
Cyproterone Acetate |
100 mg |
$43.10 |
| |
C24H29ClO4 FW 416.94 [427-51-0] |
250 mg |
$129.20 |
| |
A hepatomitogen and tumor promoter. Induces apoptosis in hepatocytes. |
1 g |
$215.30 |
| |
Oberhammer, F.A., Pavelka, M., Sharma, S., et al. Proc. Natl Acad Sci, USA. 89:5408-12 (1992). |
|
|
| |
Kasper, P., Mueller, L. Carcinogenesis. 20:2185-8 (1999). |
|
|
| |
|
|
|
| C9670 |
Cyromazine |
25 g |
$75.90 |
| |
C6H10N6 FW 166.18 [66215-27-8] |
100 g |
$255.40 |
| |
A non-organophosphorus insect growth regulator. |
|
|
| |
Jukes AA, Collier RH, Finch S. Meded. Rijksuniv Gent Fak Landbouwkd Toegep Biol Wet. 66:395-402 (2001). |
|
|
| |
Schwartz L, Wolf D, Markus A et al. J Agric Food Chem. 51:5972-6 (2003). |
|
|
| |
|
|
|
| C9673 |
Cysteamine Hydrochloride |
25 g |
$42.00 |
| |
2-Aminoethanothiol hydrochloride |
100 g |
$137.80 |
| |
C2H7NS.HCl FW 113.61 m.p. 66-680C [156-57-0] |
|
|
| |
An inhibitor of DMBA-induced mammary tumors. |
|
|
| |
Tatsuta M, Iishi H, Baba M, Taniguchi H. International Journal of Cancer. 48:605-8 (1991). |
|
|
| |
IP C, Ganther HE. Carcinogenesis. 13:1167-70 (1992). |
|
|
| |
Tatsuta M, Lishi H, Baba M, Taniguchi H. International Journal of Cancer. 44:1008-11 (1989). |
|
|
| |
|
|
|
| C9773 |
L-Cystine |
25 g |
$20.70 |
| |
C6H12N2O4S2 FW 240.30 [56-89-3] |
100 g |
$55.20 |
| |
Non-essential amino acid vital for human development formed by the |
500 g |
$207.00 |
| |
dimerization of two cysteines. Its derivatives as ligangs for neuronal nicotine receptors |
|
|
| |
and have various pharmacological activities. |
|
|
| |
Boido CC, Tasso B, Boido V, Sparatore F. Farmaco. 58:265-77 (2003). |
|
|
| |
Breining SR. Curr Top Med Chem. 4:609-29 (2004). |
|
|
| |
|
|
|
| C9778 |
Cytarabine |
100 mg |
$20.70 |
| |
Cytosine b-D-arabinofuranoside |
500 mg |
$55.10 |
| |
C9H13N3O5 FW 243.22 [147-94-4] |
1 g |
$89.60 |
| |
Cytarabine (Cytosine beta-D-arabinofuranoside) is an antimetabolite compound which is proven |
|
|
| |
to be one of the most effective agents available to treat leukemia. It exerts its cytotoxic effect |
|
|
| |
by inactivating DNA polymerases alpha, delta, and epsilon. |
|
|
| |
Tothova E, Fricova M, Kafkova A et al. Neoplasma. 47:125-8 (2000). |
|
|
| |
Mirzayans R, Cubitt S et al. Carcinogenesis. 15: 2319-24 (1994). |
|
|
| |
Okamura T, Hinyokika Kiyo. 34:1895-902 (1992). |
|
|
| |
|
|
|
| C9779 |
Cytisine |
5 mg |
$41.40 |
| |
C11H14N2O FW 190.24 [485-35-8] |
25 mg |
$138.00 |
| |
Potent ligand for many nAChR subtypes. Known for analgesic, antihypertensive |
100 mg |
$365.70 |
| |
and inotropic activities. |
|
|
| |
Boido CC, Tasso B, Boido V, Sparatore F. Farmaco. 58:265-77 (2003). |
|
|
| |
|
|
|
| C9878 |
Cytochalasin A |
1 mg |
$44.80 |
| |
C29H35NO5 FW 477.598 [14110-64-6] |
5 mg |
$192.60 |
| |
An anti-cytoskeletal drug which inhibits actin polymerization and has caused low stationary |
|
|
| |
motility and membrane ruffling in K1735-M2 mouse melanoma cells. |
|
|
| |
Suelmann R, Fischer R. Cell Motil Cytoskeleton. 45:42-50 (2000). |
|
|
| |
Torralba S, Raudaskoski M, Pedregosa AM, Laborda F. Microbiology. 144(Pt 1):45-53 (1998). |
|
|
| |
Hofmann-Wellenhof R, Smolle J, Helige C et al. Exp Dermatol. 3:219-226 (1994). |
|
|
| |
|
|
|
| C9879 |
Cytochalasin B |
1 mg |
$31.40 |
| |
C29H37NO5 FW 479.613 [14930-96-2] |
5 mg |
$114.20 |
| |
An actin-disrupting agent that blocks activated hKv1.5 channels and endogenous |
|
|
| |
I(K,ur) in a cytoskeleton-independent manner. |
|
|
| |
Choi BH, Park JA, Kim KR et al. Am J Physiol Cell Physiol. 289:C425-436 (2005). |
|
|
| |
|
|
|
| C9880 |
Cytochalasin C |
1 mg |
$98.60 |
| |
C30H37NO6 FW 507.623 [22144-76-9] |
5 mg |
$407.70 |
| |
An actin-disrupting agent that increases the rate of transcription of the TGF-beta 1 gene |
|
|
| |
and of the collagenase gene. |
|
|
| |
Varedi M, Ghahary A, Scott PG, Tredget EE. J Cell Physiol. 172:192-199 (1997). |
|
|
| |
|
|
|
| C9881 |
Cytochalasin D |
1 mg |
$98.60 |
| |
C30H37NO6 FW 507.623 [22144-77-0] |
5 mg |
$407.70 |
| |
An anti-cytoskeletal drug that promotes actin depolymerization. |
|
|
| |
|
|
|
| |
D'Souza VM, Bareford LM, Ray A, Swaan PW. J Nutr Biochem. 17:821-829 (2006). |
|
|
| |
|
|
|
| C9882 |
Cytochalasin E |
1 mg |
$47.00 |
| |
C28H33NO7 FW 495.569 [36011-19-5] |
5 mg |
$196.00 |
| |
An inhibitor of actin microfilament polymerisation that strongly induces interleukin-8 |
|
|
| |
through epithelial cell line HeLa. |
|
|
| |
Yun BW, Atkinson HA, Gaborit C et al. Plant J. 34:768-777 (2003). |
|
|
| |
Ikewaki N, Yamada A, Inoko H. Microbiol Immunol. 47:775-783 (2003). |
|
|
| |
|
|
|
| C9782 |
Cytotoxicity Test |
125 Tests |
$287.30 |
| |
|
250 Tests |
$475.40 |
| |
|
|
|