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Sulforaphane
See LKT's Specialty Chemicals
See LKT's Product Line
Alphabetized - D
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
D0011 Dacarbazine 100 mg
$34.50
  C6H10N6O FW 182.18 1 g
$180.80
  Used in the treatment of malignant melanoma and sarcomas.  
  Flaherty LE, Redman BG, Chabot GG et al. Cancer. 65:2471-2477 (1990).  
     
D0025 DAGO 1 mg
$35.80
    2 mg
$60.90
    5 mg
$107.50
     
D0032 Daidzein 250 mg
$43.10
    1 g
$129.20
  An isoflavone that inhibits metabolic activation of benzo[a]pyrene. An 5 g
$258.20
  inhibitor of hydrogenperoxide production in 12-O-tetradecanoylphorbol-13-acetate  
  stimulated HL-60 cells.  
  Chae Y-H, Ho DK, Cassady JM et al. Chem.-Biol. Int. 82:181-193 (1992).  
  Giles D, Wei H. Nutr. Cancer 29:77-82 (1997).  
     
D0033 Daidzin 1 mg
$56.00
  C21H20O9 Mol.Wt.: 416.378 [552-66-9] 5 mg
$184.80
  A kudzu isoflavone. Demonstrates chemopreventive activities by inhibiting the bioactivation  
  of carcinogenic arylamines. Daidzin is also a potent inhibitor of human mitochondrial  
  aldehye dehydrogenase.  
  Hammons et. al. Nutr. Cancer. 33: 46-52 (1999).  
  Keung WM, Vallee BL. Proc Natl Acad Sci U S A.90: 1247-51 (1993).  
     
D0044 D-Ala-D-Ala 250 mg
$62.70
  C6H12N2O3 Mol Wt: 160.17 [923-16-0]  
     
D0253 Danazol 100 mg
$48.40
  C22H27NO2 FW 337.46 [17230-88-5] 250 mg
$101.20
  It is a synthetic gonadotropin inhibitor which has preventive effects on 1 g
$378.90
  estrogen-related endometrial carcinogenesis in mice. Danazol therapy has  
  also resulted in regression of established mammary carcinoma in rats.  
  Niwa K, Hashimoto M, Morishita S et al. Cancer Lett. 158:133-9 (2000).  
  Peters TG, Lewis JD, Wilkinson EJ, Fuhrman TM. Cancer. 40: 2797-800 (1977).  
     
D0353 Danofloxacin 500 mg
$72.80
  C19H20FN3O3 FW 357.38 [112398-08-0] 1 g
$112.00
  A synthetic fluoroquinone with broad spectrum anti-bacterial activity. Used as a 5 g
$358.40
  veterinary treatment of respiratory diseases in cattle, swine and chickens.  
  Escudero, E. Journal of Veterinary Pharmacology and Therapeutics (2007), 30(6), 572-577.  
  Cox, S. K. Journal of Veterinary Pharmacology and Therapeutics (2007), 30(5), 381-386  
     
D0254 Dansyl-Y-V-G 25 mg
$164.90
  C28H34N4O7S FW 571.63 50 mg
$280.30
    125 mg
$494.60
     
D0255 Dantrolene sodium 100 mg
$43.90
  C14H9N4NaO5.31/2H2O FW 399.29 [24868-20-0] 250 mg
$81.50
  A skeletal muscle relaxant that inhibits intracellular calcium release. It has 1 g
$232.10
  shown inhibitory effects on G6PD activity both in vitro and in vivo, in  
  addition to showing antioxidant effects.  
  Beydemir S, Gulcin I, Kufrevioglu OI et al. Pol J Pharmacol. 55:787-92 (2003).  
  Buyukokuroglu ME, GulcIn I, Oktay M et al. Pharmacol Res. 44:491-4 (2001).  
  Tanii H, Taniguchi N, Tsujio I et al. Psychiat Clin Neuros. 51:415-9 (1997).
  
     
D0169 Darifenacin Hydrobromide 10 mg
$67.20
  C28H31BrN2O2 FW 507.46 [133099-07-7] 25 mg
$134.40
  Is a medication used to treat urinary incontenance. Mechanism of action is by 100 mg
$420.00
  blocking the M3 musarinnic acetylcholine receptor.  
  Chapple, C. Current Medical Research and Opinion (2007), 23(10), 2347-2358.  
  Song P. Cancer research (2007), 67(8), 3936-44.  
  Naruganahalli, K. S. European Journal of Pharmacology (2007), 572(2-3), 207-212.  
     
D0182 Daunorubicin Hydrochloride 10 mg
$103.30
  Daunomycin 50 mg
$385.50
  C27H29NO10.HCl FW 564.0 [23541-50-6] 100 mg
$671.40
  An anthracycline antibiotic clinically used as an antitumor agent.  
  Effective against leukemia. It is an inhibitor of topoisomerase II and induces apoptosis  
  by intercalation into DNA.  
  Gieseler F, Nussler V, Brieden T et al. Int. J Clin Pharmacol Ther. 36:25-8 (1998).  
  Ferraro C, Quemeneur L, Prigent AF. Cancer Res. 60:1901-7 (2000).  
  Hande K. R. Biochim Biophys Acta 1400:173-84 (1998).  
     
D1624 Deflazacort 100 mg
$39.20
  C25H31NO6 FW 441.52 [14484-47-0] 250 mg
$89.60
  A glucocorticoid with anti-inflammatory and immunosuppressive activities. 1 g
$224.00
  Deflazacort is a treatment of various muscle disorders, with the benefit of inducing  
  less bone loss compared to prednisone.  
  Schiatti P, Selva D, Barone D, Restelli A, Glasser A. Arzneimittelforschung. 30:1543-9 (1980).  
  Rizzato G, Fraioli P, Montemurro L. Chest. 99:301-9 (1991).  
     
D1627 Dehydrocostus Lactone 5 mg
$89.60
  C15H18O2 FW 230.3 [477-43-0] 10 mg
$140.00
  Inhibits NF-Kappa-B activiation by preventing TNF-alpha induced degradation 25 mg
$252.00
  and phosphorylation. Renders HL-60 cells susceptible to TNF-alpha induced apoptosis  
  by enhancing caspase3 and caspase8 activities.  
  Loizzo, M. Anticancer Research (2007), 27(5A), 3293-3300.  
  Jeong, Gil-Saeng. European Journal of Pharmacology (2007), 565(1-3), 37-44.  
     
D1629 Dehydroepiandosterone 5 g
$47.70
  DHEA 25 g
$191.20
  C19H28O2 FW 288.40 MP: 149-151oC [53-43-0] 100 g
$573.20
  A broad-spectrum cancer chemopreventive agent. A potent inhibitor  
  of glucose-6-phosphate dehydrogenase.  
  Schwartz AG, Pashko LL. J. CellBiochem.Suppl. 17G:73-79 (1993).  
     
D1628 5,6-Dehydrokawain 5 mg
$111.40
  C14H12O3 FW 228.24 10 mg
$172.10
  One of the six main active ingredients (a-pyrones) of kava kava, found to have  
  antiplatelet activity which is due to the inhibition of thromboxane A2 formation.  
  Teng CM, Hsu SY, Lin CH et al. Chin J Physiol 33:41-8 (1990).  
     
D1643 Delta Sleep Inducing Peptide 1 mg
$35.80
  C35H48N10O15 FW 848.83 [69431-45-4] 2 mg
$60.90
  A neuropeptide found in neurons, peripheral organs and plasma. It induces 5 mg
$107.50
  sleep in mammals with antistress and antihypoxic effects in rats.  
  Boglepov et. al. Morfologiia. 123:15-50 (2003).  
  Dovedova EL, Khrustalev DA, Khudoerkov RM. Bull Exp Biol Med. 140:514-6 (2005).  
     
D1644 Deltorphin 1 5 mg
$136.20
  C37H52N8O10 FW 768.87 10 mg
$231.20
  A high potency opioid neuropeptide isolated from amphibian skin. 25 mg
$408.60
  Stefano GB, Melchiorri P, Negri L et al. Proc Natl Acad Sci USA. 89:9316-20 (1992).  
     
D1748 Demeclocycline Hydrochloride 100 mg
$27.40
  C21H21ClN2O8.HCl FW 501.30 [64-73-3] 250 mg
$41.10
  A tetracycline antibacterial that has antimalarial activity. 1 g
$79.00
  Kumar A, Dutta GP. Ann Trop Med Parasit. 83:199-206 (1989).  
     
D1749 Demecolcine 1 mg
$38.90
  C21H25NO5 FW 371.43 [477-30-5] 5 mg
$94.10
  Inhibitor of spindle fiber formation in the M phase cell cycle. Induces 10 mg
$167.60
  apoptosis in V79 cells. 50 mg
$658.40
  Fujikawa-Yamamoto K, Teralka K, Zong ZP et al. Cell Struct Funct.19:391-6 (1994).  
     
D1849 4'-Demethylepipodophyllotoxin 500 mg
$52.60
  C21H20O8 FW 400.38 1 g
$82.00
  A derivative of the antitumor agent VP-16-213 in the podophyllotoxin family. 5 g
$303.40
  Van Maanen JM, van den Akker E, de Vries J et al. Eur J Cancer Clin Oncol. 24:1415-9 (1988).  
     
D1757 L-Deoxyalliin 1 g
$90.70
  S-Allyl-L-cysteine 5 g
$402.90
  C6H11NO2S FW 161.22 [21593-77-1]  
  A water soluble organosulfur compound from garlic. It is a candidate for  
  chemoprevention clinical trial.  
  Sumiyoshi H, Wargovich M. J. Cancer Res. 50:5084-5087 (1990).  
  Kelloff GJ et al. J.Cell.Biochem.Suppl. 26:1-28 (1996).  
     
D1759 Deoxynivalenol 1 mg
$103.60
  C15H20O6 FW 296.32 [51481-10-8] 5 mg
$417.20
  A Fusarium mycotoxin found in cereals, grains, and foodstuffs that can increase the  
  frequency of stillborn piglets by inhibiting protein synthesis.  
  Kamimura H, Nishijima M, Yasuda K et al. J Assoc Off Anal Chem. 64:1067-1073 (1981).  
  Diaz-Llano G, Smith TK. J Anim Sci. 84:2361-2366 (2006).  
     
D0368 Deoxysarcophine, 2-epi-16- 10 mg
$140.30
  C20H30O2 FW 302.45  
  It is a useful template for synthesis of a more active cancer chemopreventive agents. Several  
  studies were carried out in order to optimize its anticancer potential.  
  Sawant, S. S. Youssef, D. T. A. Reiland, J. and Ferniz, M. et. al. J. Nat. Prod. 691010-1013 (2006).  
  El Sayed,K.A. Hamann. M.T.Waddling,C.A.Jensen, C. and Lee, S. K. et. alJ.Org.Chem.637449-7455(1998).  
  Katsuyama, I. Fahmy, H. Zjawiony, J. K. Khalifa, S. I. And Kilada, R. W.et.alJ. Nat.Prod.651809-1814(2002).  
  Sawant, S. S. Sylvester, P. W. Avery, M. A. and Desai, P. et. al. J. Nat. Prod. 672017-2023 (2004).  
     
D1768 Dermaseptin I 0.5 mg
$121.90
  C152H257N43O44S2 FW 3455.08 1 mg
$207.90
  A 34-amino acid residue cationic antimicrobial peptide. 2.5 mg
$365.60
  Ammar B, Perianin A, Mor A et al. Biochem Biophys Res Commun. 247:870-5 (1998).  
     
D1767 Dermenkephalin 1 mg
$35.80
  C44H62N10O10S2 FW 955.17 2 mg
$60.90
    5 mg
$107.50
     
D1769 Dermorphin 1 mg
$136.20
  C40H50N8O10 FW 802.88 2 mg
$231.20
  A naturally occurring heptapeptide. It is a µ-selective opioid agonist with 5 mg
$408.60
  potent analgesic effects.  
  Melchiorri P, Negri L. Gen Pharmacol. 27:1099-107 (1996).  
  Fontani G, Vergnani L, Salvadori S et al. Life Sci. 52:323-8 (1993).  
     
D1770 Dermorphin Analog 5 mg
$35.80
  C44H59N11O10 FW 902.03 10 mg
$60.90
    25 mg
$107.50
     
D1774 Desloratadine 100 mg
$69.00
  C19H19ClN2 FW 310.82 [100643-71-8] 500 mg
$276.00
  A non-sedating H1-receptor agonist free from antimuscarinic/anticholinergic 1 g
$482.90
  effects. It has novel anti-allergic and anti-inflammatory effects.  
  Monroe EW. Skin Therapy Lett. 7:1-2, 5 (2002).  
  Henz BM. Allergy. 56 Suppl 65:7-13 (2001)  
     
D1775 Deslorelin Acetate Please inquire
  C64H83N17O12 FW 1282.47 [57773-65-6]  
  Deslorelin acetate is a potent LHRH agonist. Induction of ovulation in mares.  
     
D1776 Desmopressin 1 mg
$89.60
  Minirin 2 mg
$152.30
  C46H64N14O12S2 FW 1069.1 5 mg
$268.80
  A hemostatic agent with strong vasodilatory effects.  
  Kaufmann JE, Iezzi M, Vischer UM. J Thromb Haemost. 1:821-8 (2003).  
     
D1777 Desmopressin Acetate 1 mg
$89.60
  C46H64N14O12S2 FW 1069.24 [16679-58-6] 2 mg
$152.30
  Desmoressin acetate is a synthetic analogue of vasopressin with low vasopressor activity. 5 mg
$268.80
  Used in the treatment of nocturnal enuresis, central diabetes insipidus, polyuria, polydipsia  
  mild and moderate forms of hemophilia A and von Willebrand disease.  
     
D1873 Desoxypeganine hydrochloride 25 mg
$43.90
  C11H12N2.HCl.2H2O FW 172.23 [61939-05-7] 100 mg
$123.00
  Acetylcholinesterase inhibitor. It is used in the treatment of Alzheimer's dementia.  
  Tuliaganov N, Sadritdinov FS, Suleimanova GA.Farmakol Toksikol. 49:37-40 (1986).  
  Lockhart B, Closier M, Howard K et al. Naunyn Schmiedebergs Arch Pharmacol. 363:429-38 (2001).  
     
D1875 Desulfo-glucoraphanin 1 mg
$76.20
  C12H23NO7S2 FW 357.44 [287966-62-5] 5 mg
$302.40
  A glucoraphanin analogue.  
     
D1693 Dexamethasone 100 mg
$41.80
  C22FH29O5 FW 392.50 m.p. 262-2640C [50-02-2] 500 mg
$129.50
  A potent glucocorticoid found to inhibit pulmonary carcinogenesis. 1 g
$192.30
  Wattenberg LW. J.Cell.Biochem.Suppl. 22:162-168 (1995).  
  Wattenberg LW, Estensen RD. Cancer Res. 56:5132-5135 (1996).  
     
D1694 Dexamethasone Acetate 100 mg
$41.40
  C24H31FO6.H2O FW 452.52 [1177-87-3] 500 mg
$128.40
  A glucocorticoid found to be most effective in adjunctive treatment against 1 g
$193.20
  acute bacterial meningitis and in patients with resistant multiple myeloma.  
  Chaudhuri A. Lancet Neurol. 3:54-62 (2004).  
  Dimopoulos MA, Anagnostopoulos A, Weber D. J Clin Oncol. 21:4444-54 (2003).  
     
D1695 Dexamethasone Sodium Phosphate 100 mg
$41.40
  C22H28FO8PNa2 FW 516.4 [2392-39-4] 500 mg
$128.40
  A systemic corticosteroid. It induces apoptosis and inhibits sodium 1 g
$193.20
  phosphate symporter. Used in the treatment of emetic effects of cancer therapy and epicondylitis.  
  Hayreh SS, Zimmerman B. Ophthalmology.110:1204-15 (2003).  
  Li GF, Chen JH, Yang J et al. Di Yi Jun Yi Da Xue Xue Bao. 24:11-4 (2004).  
  Chen Y, Chen XY. Ai Zheng. 21:498-503 (2002).  
  Cassileth PA, Lusk EJ, Torri S et al. Arch Intern Med.143:1347-9 (1983).  
     
  Dexibuprofen (See S(+) Ibuprofen)  
     
D1792 Dextromethorphan Hydrobromide 5 g
$37.90
  C18H25NO.HBr FW 352.32 [125-69-9] 10 g
$68.90
  d-Form of Racemethorphan 50 g
$275.40
  Widely used as a cough suppressant. New use includes its anticonvulsive and neuro-  
  protective properties. It was found to improve cerebral ischemia. A NMDA receptor agonist.  
  Tortella FC, Pellicano M, Bowery NG. Trends Pharmacol Sci. 10:501-7 (1989).  
  Choi DW, Peters S. Viseskul V. J Pharmacol Exp Ther. 242:713-20 (1987).  
     
D3303 Diacerein 50 mg
$50.40
  C19H12O8 FW 368.29 [13739-02-1] 250 mg
$184.80
  Used for treating osteoarthritis. Interleukinn-1 inhibitor  
  Sanfelix-Gimeno G. Medicina clinica (2008), 130(12), 463-5.  
  Sharma A. Journal of the Indian Medical Association (2008), 106(1), 54-6, 58.  
     
  Diallyl disulfide (See allyl disulfide)  
     
     
D3201 Diallyl sulfide, 97% 25 ml
$33.90
  Allyl sulfide 100 ml
$107.60
  C6H10S FW 114.21 b.p. 1380C [592-88-1] d. 0.887  
  A modulator of drug metabolizing enzyme P450 system and inducer of the phase II  
  detoxifying enzyme GST. Inhibitor of chemical-induced carcinogenesis in many tissues.  
  Yang CS, Chhabra S, Hong JY, Smith TJ. J Nutr. 131:1041S-5S (2001).  
  Wargovich MJ, Imada O, Stephens LC. Cancer Lett. 64:39-42 (1992).  
  Srivastava SK, Hu X, Zaren HA et al. Cancer Lett. 118:61-67 (1997).  
     
D3202 Diallyl trisulfide 100 mg
$60.60
  C6H10S3 FW 178.34 b.p. 44-460C (0.02 mm) [2050-87-5] 500 mg
$191.30
  One of many sulfur containing compounds from garlic and onion. Inducer of 1 g
$332.30
  phase II detoxifying enzymes. It was found to inhibit tumorigenesis and suppress  
  tumor cell proliferation.  
  Sparnins VL, Barany G, Wattenberg LW. Carcinogenesis 9:131-134 (1988).  
  Sakamoto K, Lawson LD, Milner JA. Nutr Cancer. 29:152-6 (1997).  
  Hu X, Singh SV. Arch Biochem Biophys. 340:279-86 (1997).  
     
D3301 Diaveridine 1 g
$35.20
  C13H16N4O2 FW 260.29 [5355-16-8] 10 g
$188.20
  A coccidiostat and antiprotozoal drug.  
  Ono-Ogata T, Ogino T, Nishikawa M et al. Environ Mol Mutagen. 39:43-8 (2002).  
  Yoshimura H. Mutat Res. 261:149-52 (1991).  
     
D3302 Diaveridine HCl 1 g
$37.60
  C13H16N4O2.HCl FW 296.74 10 g
$194.40
     
     
     
D3304 Dibenzoylmethane 10 g
$23.30
  1,3-Diphenyl-1,3-propanedione 25 g
$43.10
  C15H12O2 FW 224.25 [120-46-7] 100 g
$129.20
  A minor constituent of licorice. It was found to inhibit mammary tumorigenesis and  
  lymphomas/leukemias in mice.  
  Lin CC, Lu YP, Lou YR et al. Cancer Lett. 168:125-32 (2001).  
  Huang MT, lou YR, Xie JG et al. Carcinogenesis 19:1697-700 (1998).  
     
D3575 2,5-Di-tert-butyl-4-hydroxyanisole 1 g
$96.00
  C15H24O2 FW 212.33 [1991-52-2] 5 g
$323.70
  An antioxidant.  
     
D3208 Diclazuril 500 mg
$43.10
  C17H10Cl2N4O2 FW 373.19 1 g
$72.40
  A benzenacetonitril anticoccidial that prevents toxoplasmosis and coccidiosis. 5 g
$284.10
  Lindsay, Dubey J. Parasitol. 86:164 (1999).  
     
     
D3209 Diclofenac, Sodium Salt 10 g
$39.40
  C14H10Cl2NNaO2 FW 318.13 [15307-79-6] 25 g
$87.40
  A non-steroidal anti-inflammatory agent with potent 100 g
$278.80
  chemopreventive activity.  
  Hixson LJ, Alberts DS, Krutzsch M et.al. Cancer Epidemiol. Biomarkers Prev. 3:433-438 (1994).  
     
  Didanosine (See 2',3'-Dideoxyinosine)  
     
D3212 2',3'-Dideoxycytidine 100 mg
$77.60
  DDC, Zalcitabine 250 mg
$165.40
  C9H13N3O3 FW 211.22 [7481-89-2] 500 mg
$292.70
  Antiviral pyrimidine nucleoside analogue effective against HIV. When activated to its triphosphate,  
  it is incorpoated into DNA by HIV-1 reverse transcriptase, causing DNA chain termination  
  and viral replication.  
  Anderson KS. Antivir Chem Chemother. 12 Suppl 1:13-7 (2001).  
  Broder S. Am J Med. 88:2S-7S (1990).  
  Akintonwa DA. Med Hypotheses. 57:249-5 (2001).  
     
D3214 2',3'-Dideoxyinosine 1 mg
$27.70
  DDI, Didanosine 5 mg
$117.40
  C10H12N4O3 FW 236.23 [69655-05-6] 25 mg
$345.00
  A potent anti-retroviral agent. Most effective in combination therapy for the  
  treatment of HIV and related lymphoma.  
  McKinney RE Jr, Cunningham CK. Curr Opin Pediatr. 16:76-9 (2004).  
  Cooper DA. J Int Assoc Physicians AIDS Care (Chic Ill). 1:15-25 (2002).  
  Wiernik PH. Semin Hematol. 38:27-31 (2001).  
     
D3218 Diethylstilbestrol 1 g
$34.50
  C18H20O2 FW 268.35 [56-53-1] 5 g
$112.10
  Synthetic estrogen. Induces apoptosis in hormone-insensitive prostate 10 g
$172.10
  cancer cells.  
  Robertson CN, Roberson KM, Padilla GM et al. J Natl Cancer Inst. 88:908-17 (1996).  
     
D3220 Difenoconazole 5 g
$33.60
  C19H17Cl2N3O3 FW 406.26 [119446-68-3] 10 g
$50.40
  Increases the production of isothiocyanates through metabolism of glucosinolates 100 g
$207.20
  Mondal, L. Pestology (2007), 31(10), 33-41.  
     
D3223 Difloxacin 5 g
$50.40
  C21H19F2N3O3 FW 399.39 [98106-17-3] 25 g
$168.00
  A quinolone antimicrobial antibiotic that may reverse drug resistance in 100 g
$504.00
  human neuroblastoma cells.  
  Norris MD, Madafiglio J, Gilbert J et al. Med Pediatr Oncol. 36:177-180 (2001).  
     
D3219 Diflubenzuron 10 g
$69.00
  C14H9ClF2N2O2 FW 310.68 [35367-38-5] 25 g
$123.00
  Benzoyl-urea insectiside, found to be a potent inhibitor of melanosome 100 g
$376.30
  synthesis in mouse melanoma cells. It has also been shown to inhibit TCDD-induced  
  CYP1A1 expression in HepG2 cells.  
  Norman JO, Meola SM. Antimicrob Agents Ch. 23:313-6 (1983).  
  Ledirac N, Delescluse C, Lesca P et al. Toxicol Appl Pharm. 164:273-9 (2000).
  
     
D3322 Diflunisal 5 g
$38.10
  C13H8F2O3 FW 250.20 [22494-42-4] 10 g
$63.70
  A non steroidal anti-inflammatory analgesic that has unusually long duration 50 g
$227.70
  of action. Recently, it was found to have anti-proliferative activity against colon adenocarcinoma cells.  
  Forbes JA, Beaver WT, White EH et al. JAMA 248:2139-2142 (1982).  
  Cannell GR, Vesey DA, Dickinson RG. Life Sci. 70:37-48 (2001).  
     
D3221 Difluoromethylornithine 10 mg
$51.60
  DFMO, Eflornitine 25 mg
$122.90
  C6H12F2N2O2 FW 182.17 [67037-37-0]  
  An irreversible inhibitor of ornithine decarboxylase. Carcinogenesis inhibitor,  
  induces apoptosis and has antiangiogenic activity.  
  Gupta S, Ahmad N, Marengo SR. Cancer Res. 60:5125-33 (2000).  
  Takahashi Y, Mai M, Nishiojka K. Int. J Cancer 85:243-7 (2000).  
  Meyskens FL Jr, Gerner EW. J Cell Biochem Suppl. 22:126-31 (1995).  
     
D3429 Dihydrocytochalasin B 1 mg
$85.10
  C29H39NO5 FW 481.62 [39156-67-7] 5 mg
$336.00
  Inhibits cellular motile processes such as membrane ruffling, axon growth cone activity,  
  blood clot retraction, cytoplasmic streaming, photodinesis, and cytokinesis.  
  Lin S, Lin DC, Flanagan MD. Proc Natl Acad Sci U S A. 75:329-333 (1978).  
     
D3328 Dihydrokainic acid 10 mg
$167.00
  C10H17NO4 FW 215.25 25 mg
$379.50
  The saturated analogue of kainic acid. Reduction of the isopropylene side-chain destroys  
  the affinity to binding sites. It enhances the antitumor activity of doxorubicin presumably  
  acting as a glutamate transporter inhibitor.  
  London ED, Klemm N, Coyle JT. Brain Res. 192:463-476 (1980).  
  Sadzuka Y, Yamashita Y, Sugiyama T, Sonobe T. Cancer Letters. 179:157-163 (2002).  
     
D3229 7,8-Dihydrokawain 5 mg
$111.40
  C14H16O3 FW 232.28 [587-63-3] 10 mg
$172.10
  One of the six main active ingredients (a-pyrones) of kava kava.  
     
D3227 Dihydromethysticin 5 mg
$111.40
  C15H16O5 FW 276.28 [3155-57-5] 10 mg
$172.10
  One of the six main kavalactones (a-pyrones) found in kava kava. It exhibits  
  neuroprotective and antinociceptive activity.  
  Backhauss C, Krieglstein J. Eur J Pharmacol 215:265-9 (1992).  
  Jamieson DD, Duffield PH. Clin Exp Pharmacol Physiol 17:495-507 (1990).  
     
D3228 Dihydromyristicin 100 mg
$57.70
  C11H14O3 FW 194.23 [607-91-0] 500 mg
$193.10
  Hydrogenated product of myristicin, a natural constituent of parsley. Inducer 1 g
$347.80
  of glutathione S-transferase enzymes.  
  Zheng G-q, Kenney PM, Lam LKT. J. Agri. Food Chem. 40:107-110 (1992).  
     
D3331 a, b-Dihydroresveratrol 10 mg
$72.80
  C14H14O FW 230.26 [58436-28-5] 25 mg
$151.20
  a, b-Dihydro-3,4',5'-trihydroxystilbene 100 mg
$448.00
  A natural phytoestrogen found ini red wine and a variety of plants. Potential  
  anti-cancer properties.  
  Ramirez-Galicia, G. Chemical Biology & Drug Design (2007), 70(2), 143-153  
     
D3330 Dihydrotanshinone 10 mg
$118.50
  C18H14O3 FW 278.30 25 mg
$250.50
  It is one of several active components of the medicinal herb 100 mg
$801.50
  Salvia miltiorrhiza Bunge. It has antibacterial and antimutagenic activities. It  
  was found to down-regulate IL-12 production at the transcription level.  
  Sato M, Sato T, Ose Y et al. Mutation. Res. 265:149-154 (1992).  
  Lee DS, Lee SH, Noh JG et al. Biosci. Biotech. Biochem. 63:2236-2239 (1999).  
  Kang BY, Chung SW, Kim SH et al. Immunopharm. 49:355-361 (2000).  
     
D3231 1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-hydroxy-3- 5 mg
$160.60
  (4-methoxy-phenyl)-propan-1-one 10 mg
$275.40
  C17H18O6 FW 318.32  
  One of the minor components of kava kava.  
     
D3230 1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-hydroxy-3- 5 mg
$160.60
  phenyl-propan-1-one 10 mg
$275.40
  C16H16O5 FW 288.30  
  One of the minor components of kava kava.  
     
D3431 3,4-Dihydroxyphenyl Ethanol 10 mg
$47.00
  3-Hydroxytyrosol 25 mg
$89.60
  C8H10O3 FW 154.16 [10597-60-1] 100 mg
$308.00
     
     
D3232 3,3'-Diindolylmethane 1 g
$23.30
  C17H14N2 FW 246.31 [1968-05-4] 5 g
$89.50
  Induces apoptosis in human MCF-7 cancer cells,independent of P53 pathway. 10 g
$161.30
  Ge X, YannaiS, Rennert G et al. Biochem Biophy Res Commun 228:153-158 (1996).  
     
D3447 Diltiazem 1 g
$50.40
  C22H26N2O4S FW 414.52 [42399-41-7] 5 g
$201.60
  Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing 10 g
$336.00
  the heart rate via strong depression of A-V node conduction. Its pharmacological  
  activity is somewhat similar to verapamil.  
  Porkin, Linda S, European Journal of Pharmacology (2008), 587(1-3), 118-123.  
     
D3348 11,12-Dimethoxydihydrokawain 5 mg
$160.60
  C16H20O5 FW 292.33 10 mg
$275.40
  One of the minor components of kava kava.  
     
     
D3351 4-Dimethylaminopyridine 10 g
$21.40
  C7H10N2 FW 122.17 25 g
$40.20
  An acylation catalyst that is more powerful than pyridine. It is used as a 100 g
$125.40
  coupling agent for the synthesis of peptides. Also found to be an effective cardiac inotropic agent in vitro.  
  Savage AO. Arch Int Pharmacod T. 273:262-76 (1985).
  
  Wang SS, Tam JP, Wang BS et al. Int J Pept Prot Res. 18:459-67 (1981).  
  Fell V, Lee CR. J Chromatogr. 121:41-7 (1976).  
     
  1,1-Dimethylbiguanide Hydrochloride (See Metformin Hydrochloride)  
     
D3353 Diminazene Aceturate 1 g
$37.60
  C22H29N9O6 FW 515.52 [908-54-3] 5 g
$156.80
  An anti-trypanosomal and anti-protozoal drug. 25 g
$577.00
  Gilbert RJ. Brit J Pharmacol. 80:133-9 (1983).  
  Diack A, Moloo SK, Peregrine AS. Vet Parisitol. 70:13-23 (1997).  
     
D3355 Diosgenin 5 g
$33.60
  C27H42O3 FW 414.62 [512-04-9] 100 g
$364.00
  A steroid sapogenin used in the semi-synthesis of cortisone, pregnenolone and  
  progesterone. The unmodified steroid has estrogenic activity and can reduce the  
  level of serum cholesterol.  
  Chiang, Chun-Te. FEBS Letters (2007), 581(30), 5735-5742.  
  Dias K. European journal of pharmacology (2007), 574(2-3), 172-8.  
     
D3356 Diosmetin 1 g
$141.10
  C16H12O6 FW 300.26 [520-34-3] 5 g
$347.80
  A natural flavonoid that inhibits human CYP1A enzyme activity. Diosmetin 25 g
$1,132.70
  has anti-mutagenic and anti-allergic characteristic.  
  Huang MT, Wood AW, Newmark HL et al. Carcinogenesis. 4:1631-7 (1983).  
  Cheong H, Ryu SY, Oak Mh et al. Arch Pharm Res. 21:478-80 (1998).  
     
D3357 Diosmin 1 g
$13.90
  C28H32O15 FW 608.54 [520-27-4] 5 g
$32.80
  A natural flavonoid that has anti-inflammatory and chemopreventive effects. 25 g
$120.50
  It was found to inhibit chemical carcinogenesis in the bladder, esophagus and colon.  
  Crespo M E, Galvez J, Cruz T et al. Planta Med. 65:651-3 (1999).  
  Yang m, Tanaka T, Hirose Y et al. Int J Cancer. 73:719-24 (1997).  
  Tanaka T, Makita H, Kawabata K et al. Carcinogenesis. 18:761-9 (1997).  
     
D3462 Diphenhydramine hydrochloride 10 g
$26.00
  Allergina 25 g
$43.10
  C17H21NO.HCl FW 291.82 [147-24-0] 100 g
$68.90
  H1 histamine receptor antagonist was found to inhibit tumor promotion.  
  Fischer SM, Patrick KE, Patamalai B, Slaga TJ. Carcinogenesis. 11:991-6 (1990).  
     
D3261 Dipropyl disulfide 25 g
$28.10
  Propyl disulfide 100 g
$84.00
  C6H14S2 FW 150.31 b.p. 195-1950C [629-16-6]  
  An inhibitor of BP-induced forestomach cancer in mice.  
  Srivastava SK, Hu X, Zaren HA et al. Cancer Lett 118: 61-67 (1997).  
     
D3262 Dipropyl sulfide 10 g
$32.30
  Propyl Sulfide  
  C6H14S FW 118.24 b.p. 142-1430C [111-47-7}  
  An inhibitor of BP-induced forestomach cancer in mice.  
  Srivastava SK, Hu X, Zaren HA et al. Cancer Lett 118:61-67 (1997).  
     
D3362 Dipyridamole 1 g
$24.90
  C24H40N8O4 FW 504.63 [58-32-2] 5 g
$69.00
  A cardiovascular drug that has antitumor properties. Inducer of FAT/CD36 25 g
$234.60
  mobilizing branch. An effective antiplatelet agent.  
  Luiken JJ, Coort SL, Willems J et al. Mol Pharmacol. 65:639-45 (2004).  
  Boyer CR, Karjian PL, Wahl GM at al. Anticancer Drugs. 13:29-36 (2002).  
     
D3372 Disodium Cycloheptylaminomethylene diphosphonate 25 mg
$40.00
  C8H17NNa2O6P2 FW 331.15 [138330-18-4] 100 mg
$98.00
  treatment of bone disorders inhibit squalene synthase and cholestrol biosynthesis 250 mg
$200.00
  Amin, Dilip, Journal of Lipid Research (1992), 33(11), 1657-63.  
     
D3374 Disulfiram 50 g
$20.70
  Tetraethylthiuram disulfide 100 g
$34.50
  C10H20N2S4 FW 296.54 [97-77-8] 250 g
$51.60
  An anti-carcinogen and DIG1 inducer. Widely used in avoidance therapy for alcohol abuse  
  and has protective effects against chemically-induced toxicity and carcinogenesis.  
  It exerts its chemopreventive effect by inhibiting metabolism of carcinogenes. It also  
  induces apoptosis.  
  Brady JF, Xiao F, Wang MH, Li Y et al. Toxicol Appl Pharmacol. 108: 366-73 (1991).  
  Proc. Am Assoc Cancer Res. 38:A3879 (1997).  
  Liu GY, Frank N, Bartsch H, Lin JK, Molecular Carcinogenesis. 22:235-46 (1998).  
     
D0010 3H-1,2-dithiole-3-thione 25 mg
$41.40
  D3T 100 mg
$138.00
  C3H2S3 FW 134.25 500 mg
$545.10
  A potent antioxidant that has chemopreventive properties. It is known to induce  
  detoxication enzymes and inhibit chemically-induced tumors in multiple tissues.  
  Otieno MA, Kensler TW, Guyton KZ. Free Radic Biol Med. 28:944-52 (2000).  
     
D4802 17-DMAG 1 mg
$85.10
  17-Dimethyaminoethylamino-demethoxygeldanamycin 5 mg
$336.00
  C32H48N4O8 FW 616.75 [467214-20-6]  
  A novel heat shock protein 90 inhibitor that enhances radiosensitization of MiaPaCa tumor cells.  
  Chatterjee M, Jain S, Stuhmer T et al. Blood 109: 720-728 (2007).  
  Dote H, Burgan WE, Camphausen K, Tofilon PJ. Cancer Res. 66:9211-9220 (2006).  
     
D4873 DMSA (Meso-2,3-dimercaptosuccinic acid) 1 g
$22.60
  Succimer 5 g
$60.30
  C4H6O4S2 FW 182.22 [304-55-2] 25 g
$225.80
  A water soluble chelating agent found to exert a hypotensive effect in  
  cultured vascular smooth muscle cells (VSMCs) from rat aorta.  
  Kramer HJ, Mensikova V, Backer A et al. Biochem Pharmacol. 65:1741-6 (2003).  
  Vineeta N, Singh V, Makkar S. J Indian Soc Pedom Prev Dent. 19:160-3 (2001).  
     
D5607 Dobutamine Hydrochloride 10 mg
$41.40
  C18H23NO3HCl FW 337.85 [49745-95-1] 50 mg
$165.60
  Inotropic agent useful in a non-invasive approach for evaluating subclinical 100 mg
$248.40
  anthra-cycline cardiotoxicity.  
  Cottin Y, L'huillier I, Casasnovas O et al. Eur J Echocardiogr. 1:180-3 (2000).  
  Subhedar NV, Shaw NJ. Cochrane Database Syst Rev. 3:CD001242 (2003).  
     
D5709 Docetaxel 5 mg
$258.20
  C43H53NO14.3H2O FW 861.91 [114977-28-5] 10 mg
$413.20
  A derivative of paclitaxel. Microtubule inhibitor. Induces apoptosis and 25 mg
$774.50
  inhibits angiogensis.  
  Wang, T.H., Wang, N.R., Mason, K.A., Milas, L. Mund-, Kiefer- und Gesichtschirurgie. 3:210-2 (1999).  
  Matsuura, M., Hasegawa, M., Hayakawa, K et al. Oncol Reports. 7:289-93 (2000).  
     
D5612 2-n-Dodecylfuran 1 g
$77.10
  C16H28O FW 212.38 [75308-12-2] 5 g
$263.90
    10 g
$479.70
     
D5746 Dolasetron 5 mg
$76.20
  C19H20N2O3 FW 324.37 [115956-12-2] 25 mg
$308.00
  An antiserotonin used as an antiemetic to prevent nausea and vomiting 100 mg
$840.00
  brought on by general anaesthesia or chemotherapy.  
  Hesketh PJ, Gandara DR, Hesketh AM et al. Support Care Cancer. 4:141-146 (1996).  
  Fujii Y. Clin Drug Investig. 26:427-437 (2006).  
     
D5649 Domperidone 50 mg
$36.00
  C22H24ClN5O2 FW 425.91 [57808-66-9] 250 mg
$138.00
  A potent inotropic agent. Effective against interleukin 2 induced hypotension. 1 g
$441.60
  Subhedar NV, Shaw NJ. Cochrane Database Syst Rev. CD001242 (2003).  
  Zeilender S, Davis D, Fairman RP, Glauser FL. Cancer Res. 49:4423-6 (1989).  
     
D5662 Dopamine Hydrochloride 5 g
$27.00
  C8H11NO2.HCl FW 189.64 [62-31-7] 25 g
$69.00
  A vasopressor that modulates cortical activation. It attenuates iNOS through 100 g
$262.20
  a D(1), beta1&2 adrenergic receptor-linked adenylate cyclase-mediated cAMP cascade.  
  Ashby FG, Casale MB. Neural Netw. 16:973-84 (2003).  
  Mazzio E, Becker A, Soliman KF. J Neuroimmunol.131:70-82 (2002).  
     
D5690 Doxazosin Mesylate 50 mg
$69.00
  Doxazosin methanesulfonate 250 mg
$276.00
  C23H25N5O5.CH3SO3H FW 547.59 [77883-43-3] 1 g
$620.90
  An alpha-blocker drug. It reduces progression of benign prostatic hyperplasia.  
  McConnell JD et al. N Engl J Med. 349:2387-98 (2003).  
  Stafford RS, Furberg CD, Finkelstein SN et al. JAMA. 291:54-62 (2004).  
     
D5692 Doxifluridine 50 mg
$86.10
  C9H11FN2O5 FW 246.19 100 mg
$158.40
  A prodrug of 5-FU converts to the active antitumor agent by pyrimidine nucleoside  
  phosphorylase. Has remarkable antitumor activity in human colorectal and advanced  
  gastrointestinal cancer.  
  De Cesare, M. Pratesi, G. De Braud, F., et al Anticancer Res. 14:549-54 (1994).  
  Di Bartolomeo M, Bajetta E, Somma L, Buzzoni R. Tumori. 81:147-50 (1995).  
     
D5792 Doxofylline 1 g
$62.20
  Doxophylline 5 g
$241.50
  C11H14N4O4 FW 266.25 [69975-86-6] 25 g
$758.90
  A novel xanthine bronchodilator known to inhibit phosphodiesterase activities.  
  Dini FL, Cogo R. Curr Med Res Opin. 16:258-68 (2001).  
     
D5794 Doxorubicin Hydrochloride 5 mg
$104.50
  14-Hydroxydaunomycin 10 mg
$183.60
  Adriamycin 50 mg
$698.20
  C27H29NO11.HCl FW 580.0 [25316-40-9]  
  An anthracycline antibiotic clinically used for chemotherapy of malignant tumors,  
  particularly solid tumors by acting on DNA topoisomerase II.  
  Giuliani FC, Liu LF, Israel M et al. Cancer Res. 49:5969-78 (1989).  
  Wasserman K, Markovits J, Jaxel C. Mol Pharmacil 38:38-45 (1990).  
     
D5897 Doxycycline Hyclate 1 g
$16.10
  Doxycycline hydrochloride hemiethanolate hemihydrate 5 g
$40.00
  C22H24N2O8.HCl.1/2(H2O).1/2(C2H6O) FW 512.9 [24390-14-5] 10 g
$71.80
  An antimicrobial agent. Used in the treatment of severe purulent inflammatory 25 g
$127.50
  diseases such as pneumonia, lung abscesses, pyothorax, skin and soft tissue  
  infections, peritonitis, purulent cholangitis and others.  
  Barkhordar RA, Russel T. J Calif Dent Assoc. 26:842-5 (1998).  
  Pozdniakova VP et al. Antibiot Khimioter. 37:43-6 (1992).  
     
D5898 Doxycycline Monohydrate 1 g
$17.10
  C22H24N2O8.H2O FW 462.45 17086-28-1] 5 g
$43.10
  Doxycycline is a synthetic teracycline. Inhibits angiogenesis in a quantitative 10 g
$77.60
  in vitro assay of angiogeneis. Inhibits proliferation of the human leukemia cell 25 g
$137.80
  line K562. It reduces lung metastases by inhibiting the secretion and acitivity  
  of matrix metalloproteinases (MMPs).  
  Fife RS, Sledge GW Jr, Sissons S, Zerler B. Cancer Lett. 153:75-8 (2000).  
  Kasono K et al. Cancer Gene Ther. 7:151-9 (2000).  
  Lokeshwar BL. Ann NY Acad Sci. 878:271-89 (1999).  
     
D6957 Droloxifene 25 mg
$72.80
  3-Hydroxytamoxifen 100 mg
$224.00
  C26H29NO2 FW 387.51 [82413-20-5] 250 mg
$392.00
  Is a phenolic analog of tamoxifen which is undergoing clinical trial for the  
  treatment of metastatic breast cancer.  
  Qin, Z. Journal of Medicinal Chemistry (2007), 50(11), 2682-2692.  
     
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