| D0025 |
DAGO |
|
|
|
|
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| D0032 |
Daidzein |
|
|
| RT |
An isoflavone that inhibits metabolic activation of
benzo[a]pyrene. An inhibitor of hydrogen peroxide production in
12-O-tetradecanoylphorbol-13-acetate stimulated HL-60 cells.
Chae Y-H, Ho DK, Cassady JM et al. Chem.-Biol. Int. 82:181-193 (1992).
Giles D, Wei H. Nutr. Cancer 29:77-82 (1997). |
250 mg
1 g
5 g |
$38.50
$115.40
$230.50 |
| D0033 |
Daidzin |
|
|
|
C21H20O9 Mol.Wt.: 416.378 [552-66-9] |
1 mg
5 mg |
$50.00
$165.00 |
| D0044 |
D-Ala-D-Ala |
|
|
|
C6H12N2O3 Mol.Wt: 160.17 [923-16-0] |
250 mg |
$56.00 |
| D0253 |
Danazol |
|
|
|
It is a synthetic gonadotropin inhibitor which has
preventive effects on estrogen-related
endometrial carcinogenesis in mice. Danazol therapy has also resulted in
regression of
established mammary carcinoma in rats.
Niwa K, Hashimoto
M, Morishita S et al. Cancer Lett. 158:133-9 (2000).
Peters TG, Lewis JD, Wilkinson EJ, Fuhrman TM. Cancer. 40: 2797-800 (1977). |
100 mg
250 mg
1 g |
$43.20
$90.40
$338.30 |
| D0254 |
Dansyl-Y-V-G |
|
|
|
|
25 mg
50 mg
125 mg |
$147.20
$250.30
$441.60 |
| D0255 |
Dantrolene sodium |
|
|
|
A skeletal muscle relaxant that inhibits
intracellular calcium release. It has shown inhibitory effects on G6PD
activity both in vitro and in vivo, in addition to showing antioxidant
effects.
Beydemir S, Gulcin I, Kufrevioglu OI et al. Pol J Pharmacol.
55:787-92 (2003).
Buyukokuroglu ME, GulcIn I, Oktay M et al. Pharmacol Res. 44:491-4
(2001).
Tanii H, Taniguchi N, Tsujio I et al. Psychiat Clin Neuros. 51:415-9
(1997). |
100 mg
250 mg
1 g |
$39.20
$72.80
$207.20 |
| D0182 |
Daunorubicin Hydrochloride |
|
|
| +4 oC |
Daunomycin
An anthracycline antibiotic clinically used as an antitumor agent. Effective
against leukemia. It is an inhibitor of topoisomerase II and induces
apoptosis
by intercalation into DNA.
Gieseler F, Nussler V, Brieden T et al.
Int. J Clin Pharmacol Ther. 36:25-8 (1998).
Ferraro C, Quemeneur L, Prigent AF. Cancer Res. 60:1901-7 (2000).
Hande K. R. Biochim Biophys Acta 1400:173-84 (1998). |
10 mg
50 mg
100 mg |
$92.20
$344.20
$599.50 |
| D1624 |
Deflazacort |
|
|
|
C25H31NO6 Mol.Wt.: 441.52 [14484-47-0]
A glucocorticoid with anti-inflammatory and immunosuppressive activities.
Deflazacort is a treatment of various muscle disorders, with the benefit of
inducing less bone loss compared toprednisone.
Schiatti P, Selva D, Barone D, Restelli A, Glasser A. Arzneimittelforschung.
30:1543-9 (1980).
Rizzato G, Fraioli P, Montemurro L. Chest. 99:301-9 (1991). |
100 mg
250 mg
1 g |
$35.00
$80.00
$200.00 |
| D1629 |
Dehydroepiandosterone |
|
|
| RT |
|
5 g
25 g
100 g |
$42.60
$170.70
$511.80 |
| D1628 |
5,6-Dehydrokawain |
|
|
|
|
5 mg
10 mg |
$99.50
$153.70 |
| D1643 |
Delta Sleep Inducing Peptide |
|
|
|
A neuropeptide found in neurons, peripheral organs
and plasma. It induces sleep in mammals with antistress and antihypoxic
effects in rats.
Boglepov et. al. Morfologiia. 123:15-50 (2003).
Dovedova EL, Khrustalev DA, Khudoerkov RM. Bull Exp Biol
Med. 140:514-6 (2005). |
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| D1644 |
Deltorphin 1 |
|
|
|
C37H52N8O10 Mol.Wt: 768.87
A high potency opioid neuropeptide isolated from amphibian skin.
Stefano GB, Melchiorri P, Negri L et al. Proc Natl Acad Sci USA.
89:9316-20 (1992). |
5 mg
10 mg
25 mg |
$121.60
$206.40
$364.80 |
| D1748 |
Demeclocycline Hydrochloride |
|
|
|
A tetracycline antibacterial that has antimalarial
activity.
Kumar A, Dutta GP. Ann Trop Med Parasit. 83:199-206 (1989). |
100 mg
250 mg
1 g |
$24.50
$36.70
$70.50 |
| D1749 |
Demecolcine |
|
|
|
Inhibitor of spindle fiber formation in the M phase
cell cycle. Induces apoptosis in V79 cells.
Fujikawa-Yamamoto K, Teralka K, Zong ZP et al. Cell Struct Funct.19:391-6
(1994). |
1 mg
5 mg
10 mg
50 mg |
$34.70
$84.00
$149.60
$587.90 |
| D1849 |
4'-Demethylepipodophyllotoxin |
|
|
|
A derivative of the antitumor agent VP-16-213 in the
podophyllotoxin family.
Van Maanen JM, van den Akker E, de Vries J et al. Eur J Cancer Clin Oncol.
24:1415-9 (1988). |
500 mg
1 g
5 g |
$47.00
$73.20
$270.90 |
| D1757 |
L-Deoxyalliin |
|
|
| +4 oC |
S-Allyl-L-cysteine
C6H11NO2 Mol.Wt.:161.22 [21593-77-1]
A water soluble organosulfur compound from garlic. It is a candidate for
chemoprevention clinical trial.
Sumiyoshi H, Wargovich M. J. Cancer Res. 50:5084-5087
(1990).
Kelloff GJ et al. J.Cell.Biochem.Suppl. 26:1-28 (1996). |
1 g
5 g |
$81.00
$359.70 |
| D1759 |
Deoxynivalenol |
|
|
|
C15H20O6 Mol. Wt. 296.32 [51481-10-8]
A Fusarium mycotoxin found in cereals, grains, and foodstuffs that can
increase the frequency of stillborn piglets by inhibiting protein
synthesis.
Kamimura H, Nishijima M, Yasuda K et al. J Assoc Off Anal
Chem. 64:1067-1073 (1981).
Diaz-Llano G, Smith TK. J Anim Sci. 84:2361-2366 (2006).
|
1 mg
5 mg |
$126.00
$500.00 |
| D0368 |
Deoxysarcophine, 2-epi-16- |
|
|
|
It is a useful template for synthesis of a more
active cancer chemopreventive agents. Several of studies were carried out in
order to optimize its anticancer potential.
Sawant, S. S. Youssef, D. T. A. Reiland, J. and Ferniz, M. et. al. J. Nat.
Prod. 691010-1013 (2006).
El Sayed, K. A. Hamann, M. T. Waddling, C. A. Jensen, C. and Lee, S. K. et.
al. J. Org. Chem.637449-7455 (1998).
Katsuyama, I. Fahmy, H. Zjawiony, J. K. Khalifa, S. I. And Kilada, R. W. et.
al.J. Nat. Prod. 651809-1814 (2002).
Sawant, S. S. Sylvester, P. W. Avery, M. A. and Desai, P. et. al. J. Nat.
Prod. 672017-2023 (2004). |
10 mg |
$125.30 |
| D1768 |
Dermaseptin I |
|
|
|
C152H257N43O44S2 Mol.Wt: 3455.08
A 34-amino acid residue cationic antimicrobial peptide.
Ammar B, Perianin A, Mor A et al. Biochem Biophys Res Commun. 247:870-5
(1998). |
0.5 mg
1 mg
2.5 mg |
$108.80
$185.60
$326.40 |
| D1767 |
Dermenkephalin |
|
|
|
|
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| D1769 |
Dermorphin |
|
|
|
C40H50N8O10 Mol.Wt: 802.88
A naturally occurring heptapeptide. It is a µ-selective opioid agonist with
potent analgesic effects.
Melchiorri P, Negri L. Gen Pharmacol. 27:1099-107 (1996).
Fontani G, Vergnani L, Salvadori S et al.
Life Sci. 52:323-8 (1993). |
1 mg
2 mg
5 mg |
$121.60
$206.40
$364.80 |
| D1770 |
Dermorphin Analog |
|
|
|
|
5 mg
10 mg
25 mg |
$32.00
$54.40
$96.00 |
| D1774 |
Desloratadine |
|
|
|
A non-sedating H1-receptor agonist free from
antimuscarinic/anticholinergic effects. It has novel anti-allergic and
anti-inflammatory effects.
Monroe EW. Skin Therapy Lett. 7:1-2, 5 (2002).
Henz BM. Allergy. 56 Suppl 65:7-13 (2001). |
100 mg
500 mg
1 g |
$61.60
$246.40
$431.20 |
| D1775 |
Deslorelin Acetate |
|
|
|
Deslorelin acetate is a potent LHRH agonist. Induction of
ovulation in mares. |
|
Please inquire |
| D1776 |
Desmopressin |
|
|
|
Minirin
C46H64N14O12S2 Mol.Wt: 1069.1
A hemostatic agent with strong vasodilatory effects.
Kaufmann JE, Iezzi M, Vischer UM. J Thromb Haemost. 1:821-8 (2003). |
1 mg
2 mg
5 mg |
$80.00
$136.00
$240.00 |
| D1777 |
Desmopressin Acetate |
|
|
|
Desmoressin acetate is a synthetic analogue of
vasopressin with low vasopressor activity. Used in the treatment of nocturnal
enuresis, central diabetes insipidus, polyuria, polydipsia mild and moderate
forms of hemophilia A and von Willebrand disease. |
|
Please inquire |
| D1873 |
Desoxypeganine hydrochloride |
|
|
|
Acetylcholinesterase inhibitor. It is used in the
treatment of Alzheimer's dementia.
Tuliaganov N, Sadritdinov FS, Suleimanova GA.Farmakol Toksikol. 49:37-40
(1986).
Lockhart B, Closier M, Howard K et al. Naunyn Schmiedebergs Arch Pharmacol. 363:429-38
(2001). |
25 mg
100 mg |
$39.20
$109.80 |
| D1693 |
Dexamethasone |
|
|
| RT |
A potent glucocorticoid found to inhibit pulmonary
carcinogenesis.
Wattenberg LW. J.Cell.Biochem.Suppl. 22:162-168 (1995).
Wattenberg LW, Estensen RD. Cancer Res. 56:5132-5135 (1996). |
100 mg
500 mg
1 g |
$37.30
$115.60
$171.70 |
| D1694 |
Dexamethasone Acetate |
|
|
|
A glucocorticoid found to be most effective in
adjunctive treatment against acute bacterial meningitis and in patients with
resistant multiple myeloma.
Chaudhuri A. Lancet Neurol. 3:54-62 (2004).
Dimopoulos MA, Anagnostopoulos A, Weber D. J Clin
Oncol. 21:4444-54 (2003). |
100 mg
500 mg
1 g |
$37.00
$114.60
$172.50 |
| D1695 |
Dexamethasone Sodium Phosphate |
|
|
|
A systemic corticosteroid. It induces apoptosis and
inhibits sodium phosphate symporter. Used in the treatment of emetic effects
of cancer therapy and epicondylitis.
Hayreh SS, Zimmerman B. Ophthal Mol.gy.110:1204-15 (2003).
Li GF, Chen JH, Yang
J et al. Di Yi Jun Yi Da Xue Xue Bao. 24:11-4 (2004).
Chen Y, Chen XY. Ai Zheng. 21:498-503 (2002).
Cassileth PA, Lusk EJ, Torri S et al. Arch Intern Med.143:1347-9 (1983). |
100 mg
500 mg
1 g |
$37.00
$114.60
$172.50
|
|
Dexibuprofen |
|
|
|
See S(+) Ibuprofen |
|
|
| D1792 |
Dextromethorphan Hydrobromide |
|
|
| RT |
d-Form of Racemethorphan
Widely used as a cough suppressant. New use includes its anticonvulsive and
neuroprotective properties. It was found to improve cerebral ischemia. A NMDA
receptor agonist.
Tortella FC, Pellicano M, Bowery NG. Trends Pharmacol
Sci. 10:501-7 (1989).
Choi DW, Peters S. Viseskul V. J Pharmacol Exp Ther. 242:713-20 (1987). |
5 g
10 g
50 g |
$33.80
$61.50
$245.90 |
|
Diallyl disulfide |
|
|
|
See allyl disulfide |
|
|
| D3201 |
Diallyl sulfide, 97% |
|
|
| +4 oC |
A modulator of drug metabolizing enzyme P450 system
and inducer of the phase II detoxifying enzyme GST. Inhibitor of
chemical-induced carcinogenesis in many tissues.
Yang CS, Chhabra S, Hong JY, Smith TJ. J Nutr. 131:1041S-5S (2001).
Wargovich
MJ, Imada O, Stephens LC. Cancer Lett. 64:39-42 (1992).
Srivastava SK, Hu X, Zaren HA et al. Cancer Lett. 118:61-67 (1997). |
25 ml
100 ml |
$30.30
$96.10 |
| D3202 |
Diallyl trisulfide |
|
|
| -20 oC |
One of many sulfur containing compounds from garlic
and onion. Inducer of phase II detoxifying enzymes. It was found to inhibit
tumorigenesis and suppress tumor cell proliferation.
Sparnins VL, Barany G, Wattenberg LW. Carcinogenesis 9:131-134 (1988).
Sakamoto K, Lawson LD, Milner JA. Nutr Cancer. 29:152-6 (1997).
Hu X, Singh SV. Arch Biochem Biophys. 340:279-86 (1997). |
100 mg
500 mg
1 g |
$54.10
$170.80
$296.70 |
| D3301 |
Diaveridine |
|
|
|
A coccidiostat and antiprotozoal drug.
Ono-Ogata T, Ogino T, Nishikawa M et al. Environ Mol.Mutagen. 39:43-8
(2002).
Yoshimura H. Mutat Res. 261:149-52 (1991). |
1 g
10 g |
$31.40
$168.00 |
| D3302 |
Diaveridine HCl |
|
|
|
|
1 g
10 g |
$33.60
$173.60 |
| D3304 |
Dibenzoylmethane |
|
|
|
1,3-Diphenyl-1,3-propanedione
A minor constituent of licorice. It was found to inhibit mammary
tumorigenesis and lymphomas/leukemias in mice.
Lin CC, Lu YP, Lou YR et al. Cancer Lett. 168:125-32 (2001).
Huang MT, lou YR, Xie JG et al.
Carcinogenesis 19:1697-700 (1998). |
10 g
25 g
100 g |
$20.80
$38.50
$115.40 |
| D3575 |
2,5-Di-tert-butyl-4-hydroxyanisole |
|
|
| +4 oC |
An antioxidant. |
1 g
5 g |
$85.70
$289.00 |
| D3208 |
Diclazuril |
|
|
| RT |
A benzenacetonitril anticoccidial that prevents
toxoplasmosis and coccidiosis.
Lindsay, Dubey J. Parasitol. 86:164 (1999). |
500 mg |
$38.50
$64.60
$253.70 |
| D3209 |
Diclofenac, Sodium Salt |
|
|
|
A non-steroidal anti-inflammatory agent with potent
chemopreventive activity.
Hixson LJ, Alberts DS, Krutzsch M et.al. Cancer Epidemiol. Biomarkers Prev.
3:433-438 (1994). |
10 g
25 g
100 g |
$35.20
$78.00
$248.90 |
|
Didanosine |
|
|
|
See 2',3'-Dideoxyinosine |
|
|
| D3212 |
2',3'-Dideoxycytidine |
|
|
|
DDC, Zalcitabine
Antiviral pyrimidine nucleoside analogue effective against HIV. When
activated to its triphosphate, it is incorpoated into DNA by HIV-1 reverse
transcriptase, causing DNA chain termination and viral replication.
Anderson KS. Antivir
Chem Chemother. 12 Suppl 1:13-7 (2001).
Broder S. Am J Med. 88:2S-7S (1990).
Akintonwa DA. Med Hypotheses. 57:249-5 (2001). |
100 mg
250 mg
500 mg |
$69.30
$147.70
$261.30 |
| D3214 |
2',3'-Dideoxyinosine |
|
|
|
DDI, Didanosine
A potent anti-retroviral agent. Most effective in combination therapy for
the treatment of HIV and related lymphoma.
McKinney RE Jr, Cunningham CK. Curr Opin Pediatr. 16:76-9 (2004).
Cooper DA. J Int Assoc Physicians AIDS
Care (Chic Ill). 1:15-25 (2002).
Wiernik PH. Semin Hematol. 38:27-31 (2001). |
1 mg
5 mg
25 mg |
$24.70
$104.80
$308.00 |
| D3218 |
Diethylstilbestrol |
|
|
|
Synthetic estrogen. Induces apoptosis in
hormone-insensitive prostate cancer cells.
Robertson CN, Roberson KM, Padilla GM et al. J Natl Cancer Inst. 88:908-17
(1996). |
1 g
5 g
10 g |
$30.80
$100.10
$153.70 |
| D3223 |
Difloxacin |
|
|
|
C21H19F2N3O3 Mol. Wt. 399.39
[98106-17-3]
A quinolone antimicrobial antibiotic that may reverse drug resistance in
human neuroblastoma cells.
Norris MD, Madafiglio J, Gilbert J et al. Med Pediatr Oncol. 36:177-180
(2001). |
5 g
25 g
100 g |
$45.00
$150.00
$450.00 |
| D3219 |
Diflubenzuron |
|
|
|
Benzoyl-urea insectiside, found to be a potent
inhibitor of melanosome synthesis in mouse melanoma cells. It has also been
shown to inhibit TCDD-induced CYP1A1 expression in HepG2 cells.
Norman JO, Meola SM. Antimicrob Agents Ch. 23:313-6 (1983).
Ledirac N, Delescluse C, Lesca P et al. Toxicol Appl Pharm. 164:273-9
(2000). |
10 g
25 g
100 g |
$61.60
$109.80
$336.00 |
| D3322 |
Diflunisal |
|
|
|
A non steroidal anti-inflammatory analgesic that has
unusually long duration of action. Recently, it was found to have
anti-proliferative activity against colon adenocarcinoma cells.
Forbes JA, Beaver WT, White EH et al. JAMA 248:2139-2142 (1982).
Cannell GR, Vesey DA, Dickinson RG. Life Sci. 70:37-48 (2001). |
5 g
10 g
50 g |
$34.00
$56.90
$203.30 |
| D3221 |
Difluoromethylornithine |
|
|
| -20 oC |
DFMO, Eflornitine
An irreversible inhibitor of ornithine
decarboxylase. Carcinogenesis inhibitor, induces apoptosis and has
antiangiogenic activity.
Gupta S, Ahmad N, Marengo SR. Cancer Res. 60:5125-33 (2000).
Takahashi Y, Mai M, Nishiojka K. Int. J Cancer 85:243-7
(2000).
Meyskens FL Jr, Gerner EW. J Cell Biochem Suppl. 22:126-31 (1995). |
10 mg
25 mg |
$46.10
$109.70 |
| D3429 |
Dihydrocytochalasin B |
|
|
|
C29H39NO5 Mol. Wt. 481.62
[39156-67-7]
Inhibits cellular motile processes such as membrane ruffling, axon growth
cone activity, blood clot retraction, cytoplasmic streaming, photodinesis,
and cytokinesis.
Lin S, Lin DC, Flanagan MD. Proc Natl Acad Sci U S A.
75:329-333 (1978). |
1 mg
5 mg |
$76.00
$300.00 |
| D3328 |
Dihydrokainic acid |
|
|
|
The saturated analogue of kainic acid. Reduction of
the isopropylene side-chain destroysthe affinity to binding sites. It
enhances the antitumor activity of doxorubicin presumably acting as a
glutamate transporter inhibitor.
London ED, Klemm N, Coyle JT. Brain
Res. 192:463-476 (1980).
Sadzuka Y, Yamashita Y, Sugiyama T, Sonobe T. Cancer Letters. 179:157-163
(2002). |
10 mg
25 mg |
$149.10
$338.80 |
| D3229 |
7,8-Dihydrokawain |
|
|
|
One of the six main active ingredients (a-pyrones) of kava
kava. |
5 mg
10 mg |
$99.50
$153.70 |
| D3227 |
Dihydromethysticin |
|
|
|
One of the six main kavalactones (a-pyrones) found
in kava kava. It exhibits neuroprotective and antinociceptive activity.
Backhauss C, Krieglstein J. Eur J Pharmacol 215:265-9 (1992).
Jamieson DD, Duffield PH. Clin Exp Pharmacol Physiol 17:495-507
(1990). |
5 mg
10 mg |
$99.50
$153.70 |
| D3228 |
Dihydromyristicin |
|
|
| -20 oC |
Hydrogenated product of myristicin, a natural
constituent of parsley. Inducer of glutathione S-transferase enzymes.
Zheng G-q, Kenney PM, Lam LKT. J. Agri. Food Chem. 40:107-110 (1992). |
100 mg
500 mg
1 g |
$51.50
$172.40
$310.50 |
| D3330 |
Dihydrotanshinone |
|
|
|
It is one of several active components of the
medicinal herb Salvia miltiorrhiza Bunge. It has antibacterial and
antimutagenic activities. It was found to down-regulate IL-12 production at
the transcription level.
Sato M, Sato T, Ose Y et al. Mutation. Res.
265:149-154 (1992).
Lee DS, Lee SH, Noh JG et al. Biosci. Biotech. Biochem. 63:2236-2239
(1999).
Kang BY, Chung SW, Kim SH et al. Immunopharm. 49:355-361 (2000). |
10 mg
25 mg
100 mg |
$105.80
$223.70
$715.60 |
| D3231 |
1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-hydroxy-3- |
|
|
|
(4-methoxy-phenyl)-propan-1-one
One of the minor components of kava kava. |
5 mg
10 mg |
$143.40
$245.90 |
|
|
|
|
| D3230 |
1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-hydroxy-3- |
|
|
|
phenyl-propan-1-one
One of the minor components of kava kava. |
5 mg
10 mg |
$143.40
$245.90 |
| D3232 |
3,3'-Diindolylmethane |
|
|
| RT |
Induces apoptosis in human MCF-7 cancer cells,
independent of P53 pathway.
Ge X, YannaiS, Rennert G et al. Biochem Biophy Res Commun 228:153-158
(1996). |
1 g
5 g
10 g |
$20.80
$79.90
$144.00 |
| D3348 |
11,12-Dimethoxydihydrokawain |
|
|
|
One of the minor components of kava kava. |
5 mg
10 mg |
$143.40
$245.90 |
| D3351 |
4-Dimethylaminopyridine |
|
|
|
An acylation catalyst that is more powerful than
pyridine. It is used as a coupling agent for the synthesis of peptides.
Also found to be an effective cardiac inotropic agent in vitro.
Savage AO. Arch Int Pharmacod T. 273:262-76 (1985).
Wang
SS, Tam JP, Wang BS et al. Int J Pept Prot Res. 18:459-67 (1981).
Fell V, Lee CR. J Chromatogr. 121:41-7 (1976). |
10 g
25 g
100 g |
$19.10
$35.90
$112.00 |
| D3353 |
Diminazene Aceturate |
|
|
|
An anti-trypanosomal and anti-protozoal drug.
Gilbert RJ. Brit J Pharmacol. 80:133-9 (1983).
Diack A, Mol.o SK, Peregrine AS. Vet Parisitol. 70:13-23 (1997). |
1 g
5 g
25 g |
$33.60
$140.00
$515.20 |
| D3356 |
Diosmetin |
|
|
|
A natural flavonoid that inhibits human CYP1A enzyme
activity. Diosmetin has anti-mutagenic and anti-allergic
characteristic.
Huang MT, Wood AW, Newmark HL et al. Carcinogenesis. 4:1631-7 (1983).
Cheong H, Ryu SY, Oak Mh et al. Arch Pharm Res.
21:478-80 (1998). |
1 g
5 g
25 g |
$126.00
$310.50
$1,011.30 |
| D3357 |
Diosmin |
|
|
|
A natural flavonoid that has anti-inflammatory and
chemopreventive effects. It was found to inhibit chemical carcinogenesis in
the bladder, esophagus and colon.
Crespo M E, Galvez J, Cruz T et al. Planta Med. 65:651-3 (1999).
Yang m, Tanaka T,
Hirose Y et al. Int J Cancer. 73:719-24 (1997).
Tanaka T, Makita H, Kawabata K et al. Carcinogenesis. 18:761-9 (1997). |
1 g
5 g
25 g |
$12.40
$29.30
$107.60 |
| D3462 |
Diphenhydramine hydrochloride |
|
|
|
Allergina
H1 histamine receptor antagonist was found to inhibit tumor promotion.
Fischer SM, Patrick KE, Patamalai B, Slaga TJ. Carcinogenesis. 11:991-6
(1990). |
10 g
25 g
100 g |
$23.20
$38.50
$61.50 |
| D3261 |
Dipropyl disulfide |
|
|
| RT |
An inhibitor of BP-induced forestomach cancer in
mice.
Srivastava SK, Hu X, Zaren HA et al. Cancer Lett 118: 61-67 (1997). |
25 g
100 g |
$25.10
$75.00 |
| D3262 |
Dipropyl sulfide |
|
|
| RT |
An inhibitor of BP-induced forestomach cancer in
mice.
Srivastava SK, Hu X, Zaren HA et al. Cancer Lett 118:61-67 (1997). |
10 g |
$28.80 |
| D3362 |
Dipyridamole |
|
|
|
A cardiovascular drug that has antitumor properties.
Inducer of FAT/CD36 mobilizing branch. An effective antiplatelet agent.
Luiken JJ, Coort SL, Willems J et al. Mol.Pharmacol. 65:639-45 (2004).
Boyer CR, Karjian PL, Wahl GM at al. Anticancer
Drugs. 13:29-36 (2002). |
|
|
| D3374 |
Disulfiram |
|
|
|
Tetraethylthiuram disulfide
An anti-carcinogen and DIG1 inducer. Widely used in avoidance therapy for
alcohol abuse and has protective effects against chemically-induced toxicity
and carcinogenesis. It exerts its chemopreventive effect by inhibiting
metabolism of carcinogenes. It also induces apoptosis.
Brady JF, Xiao F, Wang MH, Li Y et al. Toxicol Appl Pharmacol. 108: 366-73
(1991).
Proc. Am Assoc Cancer Res. 38:A3879 (1997).
Liu GY, Frank N, Bartsch H, Lin JK, Molecular Carcinogenesis.
22:235-46 (1998). |
50 g
100 g
250 g |
$18.50
$30.80
$46.10 |
| D0010 |
3H-1,2-dithiole-3-thione |
|
|
|
D3T
A potent antioxidant that has chemopreventive properties. It is known to
induce detoxication enzymes and inhibit chemically-induced tumors in multiple
tissues.
Otieno MA, Kensler TW, Guyton KZ. Free Radic Biol Med. 28:944-52 (2000). |
25 mg
100 mg
500 mg |
$37.00
$123.20
$486.70 |
| D4802 |
17-DMAG |
|
|
|
17-Dimethyaminoethylamino-demethoxygeldanamycin
C32H48N4O8 Mol. Wt. 616.75 [467214-20-6]
A novel heat shock protein 90 inhibitor that enhances radiosensitization of
MiaPaCa tumor cells.
Chatterjee M, Jain S, Stuhmer T et al. Blood 109:
720-728 (2007).
Dote H, Burgan WE, Camphausen K, Tofilon PJ. Cancer Res. 66:9211-9220
(2006). |
1 mg
5 mg |
$76.00
$300.00 |
| D4873 |
DMSA (Meso-2,3-dimercaptosuccinic acid) |
|
|
|
Succimer
A water soluble chelating agent found to exert a hypotensive effect in
cultured vascular smooth muscle cells (VSMCs) from rat aorta.
Kramer HJ, Mensikova V, Backer A et al. Biochem Pharmacol. 65:1741-6
(2003).
Vineeta N, Singh V, Makkar S. J Indian Soc Pedom Prev Dent.
19:160-3 (2001). |
1 g
5 g
25 g |
$20.20
$53.80
$201.60 |
| D5607 |
Dobutamine Hydrochloride |
|
|
|
Inotropic agent useful in a non-invasive approach
for evaluating subclinical anthracycline cardiotoxicity.
Cottin Y, L'huillier I, Casasnovas O et al. Eur J Echocardiogr. 1:180-3
(2000).
Subhedar NV, Shaw NJ. Cochrane Database Syst Rev. 3:CD001242
(2003). |
10 mg
50 mg
100 mg |
$37.00
$147.90
$221.80 |
| D5709 |
Docetaxel |
|
|
| -20 oC |
A derivative of paclitaxel. Microtubule inhibitor.
Induces apoptosis and inhibits angiogensis.
Wang, T.H., Wang, N.R., Mason, K.A., Milas, L. Mund-, Kiefer- und
Gesichtschirurgie. 3:210-2 (1999).
Matsuura, M., Hasegawa, M., Hayakawa, K et
al. Oncol Reports. 7:289-93 (2000). |
5 mg
10 mg
25 mg |
$230.50
$368.90
$691.50 |
| D5612 |
2-n-Dodecylfuran |
|
|
| 4 oC |
|
1 g
5 g
10 g |
$68.80
$235.60
$428.30 |
| D5746 |
Dolasetron |
|
|
|
C19H20N2O3 Mol. Wt. 324.37
[115956-12-2]
An antiserotonin used as an antiemetic to prevent nausea and vomiting
brought on by general anaesthesia or chemotherapy.
Hesketh PJ, Gandara DR, Hesketh AM et al. Support Care Cancer. 4:141-146
(1996).
Fujii Y. Clin Drug Investig. 26:427-437 (2006). |
5 mg
25 mg
100 mg |
$68.00
$275.00
$750.00 |
| D5649 |
Domperidone |
|
|
|
A potent inotropic agent. Effective against
interleukin 2 induced hypotension.
Subhedar NV, Shaw NJ. Cochrane Database Syst Rev. CD001242 (2003).
Zeilender S, Davis D, Fairman RP, Glauser FL. Cancer Res. 49:4423-6 (1989). |
50 mg
250 mg
1 g |
$32.10
$123.20
$394.30 |
| D5662 |
Dopamine Hydrochloride |
|
|
|
A vasopressor that modulates cortical activation. It
attenuates iNOS through a D(1), beta1&2 adrenergic receptor-linked adenylate cyclase-mediated cAMP
cascade.
Ashby FG, Casale MB. Neural Netw. 16:973-84 (2003).
Mazzio E, Becker A,
Soliman KF. J Neuroimmunol.131:70-82 (2002). |
5 g
25 g
100 g |
$24.10
$61.60
$234.10 |
| D5690 |
Doxazosin Mesylate |
|
|
|
Doxazosin methanesulfonate
An alpha-blocker drug. It reduces progression of benign prostatic
hyperplasia.
McConnell JD et al. N Engl J Med. 349:2387-98 (2003).
Stafford RS, Furberg CD, Finkelstein SN et al. JAMA. 291:54-62 (2004). |
50 mg
250 mg
1 g |
$61.60
$246.40
$554.40 |
| D5692 |
Doxifluridine |
|
|
| RT |
A prodrug of 5-FU converts to the active antitumor
agent by pyrimidine nucleoside phosphorylase. Has remarkable antitumor
activity in human colorectal and advanced
gastrointestinal cancer.
De Cesare, M. Pratesi, G. De Braud, F., et al Anticancer
Res. 14:549-54 (1994).
Di Bartolomeo M, Bajetta E, Somma L, Buzzoni R. Tumori. 81:147-50 (1995). |
50 mg
100 mg |
$76.90
$141.40 |
| D5792 |
Doxofylline |
|
|
|
Doxophylline
A novel xanthine bronchodilator known to inhibit phosphodiesterase
activities.
Dini FL, Cogo R. Curr Med Res Opin. 16:258-68 (2001). |
1 g
5 g
25 g |
$55.50
$215.60
$677.60 |
| D5794 |
Doxorubicin Hydrochloride |
|
|
| 4 oC |
14-Hydroxydaunomycin
Adriamycin
An anthracycline antibiotic clinically used for chemotherapy of malignant
tumors, particularly solid tumors by acting on DNA topoisomerase II.
Giuliani FC, Liu LF, Israel M et al. Cancer Res. 49:5969-78
(1989).
Wasserman K, Markovits J, Jaxel C. Mol.Pharmacil 38:38-45 (1990). |
5 mg
10 mg
50 mg |
$93.30
$163.90
$623.40 |
| D5897 |
Doxycycline Hyclate |
|
|
|
Doxycycline hydrochloride hemiethanolate
hemihydrate
An antimicrobial agent. Used in the treatment of severe purulent
inflammatory diseases such as pneumonia, lung abscesses, pyothorax, skin and
soft tissue infections, peritonitis, purulent cholangitis and others.
Barkhordar RA, Russel T. J Calif Dent Assoc. 26:842-5 (1998).
Pozdniakova VP et al. Antibiot Khimioter. 37:43-6 (1992). |
1 g
5 g
10 g
25 g |
$14.40
$35.70
$64.10
$113.80 |
| D5898 |
Doxycycline Monohydrate |
|
|
|
Doxycycline is a synthetic teracycline. Inhibits
angiogenesis in a quantitative in vitro assay of angiogeneis. Inhibits
proliferation of the human leukemia cell line K562. It reduces lung
metastases by inhibiting the secretion and acitivity of matrix metalloproteinases
(MMPs).
Fife RS, Sledge GW Jr, Sissons S, Zerler B. Cancer Lett. 153:75-8 (2000).
Kasono K et al. Cancer Gene Ther. 7:151-9 (2000).
Lokeshwar BL. Ann NY Acad Sci. 878:271-89 (1999). |
1 g
5 g
10 g
25 g |
$15.30
$38.50
$69.30
$123.00 |
