| E0403 |
Ebastine |
1 g |
$56.00 |
| |
C32H39NO2 FW 469.66 [90729-43-4] |
5 g |
$224.00 |
| |
A non-sedating histamine H1 receptor antagonist that also inhibits T cell migration and may |
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| |
find a use in the treatment of Th2-type autoimmune diseases. |
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| |
Roberts DJ. Drugs. 52 Suppl 1:8-14 (1996). |
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| |
Nori M, Iwata S, Munakata Y et al. Clin Exp Allergy. 33:1544-1554 (2003). |
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| |
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|
| E0073 |
Ebselen |
5 mg |
$39.20 |
| |
C13H9NOSe FW 274.18 [60940-34-3] |
25 mg |
$89.60 |
| |
A seleno-organic compound showing glutathione peroxidase-like activity that has |
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| |
anti-inflammatory, anti-oxidant, and anti-malarial effects. It has been shown to inhibit |
|
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| |
NO-induced apoptosis of differentiated PC12 cells and protect Ca2+ blockage. |
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| |
Moretto MB, Franco J, Posser T et al. Neurochem Res. 29:1801-6 (2004). |
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| |
Lindenblatt N, Schareck W, Belusa L et al. Thromb Haemostasis. 90:882-92 (2003). |
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| |
Sarker KP, Biswas KK, Rosales JL et al. J Neurochem. 87:1345-53 (2003). |
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| |
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| E0812 |
b-Ecdysone |
1 mg |
$30.90 |
| |
(2b, 3b, 14a, 20, 22[R], 25-Hexahydroxy-7-cholesten-6-one) |
5 mg |
$103.30 |
| |
C27H44O7 FW 480.63 [5289-74-7] |
25 mg |
$361.40 |
| |
Insect development hormone that stimulates DNA synthesis in animal lymphocytes |
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| |
activated by polyclonal mitogens. |
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| |
Fomovskaia GN, Berdyshev AG, Kholodova ID. Ukr Biokhim Zh. 64:56-61 (1992). |
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| |
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| E0813 |
Ecdysterone |
5 mg |
$96.70 |
| |
20-Hydroxyecdysone |
10 mg |
$172.50 |
| |
C27H44O7 FW 480.63 [5289-74-7] |
25 mg |
$345.00 |
| |
A steroid hormone used as anobolic drug, found to induce apoptosis. |
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| |
It modulates antitumor activity of cytostatics and biosynthesis of macromolecules. |
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| |
Thummel CS. Insect Biochem Mol Biol. 32:113-20 (2002). |
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| |
Buszczak M, Segraves WA. Curr Biol. 10:R830-3 (2000). |
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| |
Konovalova NP, Mitrokhin IuI, Volkova LM et al. Izv Akad Nauk Ser Biol. 6:650-8 (2002). |
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| |
|
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|
| E2424 |
Egg Laying Hormone of Aplysia |
0.5 mg |
$152.32 |
| |
C190H329N59O57S1 FW 4384.17 |
1 mg |
$258.94 |
| |
|
2.5 mg |
$490.32 |
| |
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| |
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|
| E4408 |
Elcatonin Acetate |
Please inquire |
|
| |
C148H244N42O47 FW 3363.8 [60731-46-6] |
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| |
A synthetic eel calcitonin analogue. For the treatment of osteoporosis, pagetŐs disease and hypercalcemia. |
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| |
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| |
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| E4416 |
Eledoisin |
1 mg |
$35.80 |
| |
C54H85N13O15S1 FW 1188.44 |
2 mg |
$60.90 |
| |
A potent vasodilating peptide that increases vascular permeability. |
5 mg |
$107.50 |
| |
Sicuteri F, Michelacci S, Lombardi V, Fanciullacci M.Arch Int Pharmacodyn Ther. 151:3 8-40 (1964). |
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| |
Saria A, Yan Z, Wolf G, Loidolt D, Martling CR, Lundberg JM. Acta Otolaryngol Suppl. 457: 25-8 (1989). |
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| |
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|
| E4417 |
Eledoisin Related Peptide |
5 mg |
$71.70 |
| |
C34H58N8O6S FW 706.96 |
10 mg |
$121.90 |
| |
|
25 mg |
$215.00 |
| |
|
|
|
| E4419 |
Eletriptan Free Base |
1 mg |
$98.00 |
| |
C22H25N2O2S FW 382.52 [143322-58-1] |
5 mg |
$425.00 |
| |
used treatment of migraine headaches. |
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| |
Spierings E L, Neurology (2000), 55(5), 735; author reply 736. |
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| |
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| E4444 |
Ellagic acid |
10 g |
$98.00 |
| |
C14H6O8 FW 302.20 m.p. >3000C [476-66-4] |
50 g |
$332.40 |
| |
Polyphenol found in plants. Its precursors are ellagitannins commonly present in |
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| |
grapes, pomegranates, raspberries, and strawberries. It is an inhibitor of Phase I enzymes, |
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| |
an inducer of Phase II enzymes and an inhibitor of chemical carcinogenesis. |
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| |
Bate-SmithECInThePharmacologyofPlantPhenolicsFairbairn,J.W.,Ed.,AcademicPress:NY133-147(1959). |
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| |
Mandal S, Shivapurkar N, Galati AJ, Stoner GD. Carcinogenesis. 9:1313-16 (1988). |
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| |
Das M, Bickers DR, Mukhtar H. Carcinogenesis 6:1409-13 (1985). |
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| |
Siglin JC, Barch DH, Stoner GD. Carcinogenesis 16:1101-1106 (1995). |
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| |
|
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|
| E4902 |
Emamectin B1 Benzoate |
100 mg |
$37.60 |
| |
C49H75NO13 FW 886.12 [137512-74-4] |
250 mg |
$62.70 |
| |
An avermectin pesticide. It has been shown to cause neurotoxicity in rats at |
1 g |
$188.20 |
| |
high doses. |
|
|
| |
Wise LD, Allen HL, Hoe CM et al. Neurotoxicol Teratol. 19:315-26 (1997). |
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| |
Hakalahti T, Lankinen Y, Valtonen ET. Dis Aquat Organ. 60:197-204 (2004). |
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| |
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|
| E5057 |
Emodin |
100 mg |
$56.00 |
| |
C15H10O5 FW 270.24 [518-82-1] |
250 mg |
$112.00 |
| |
A purgative resin from Himalayan Rhubarn which displays inhibitory effects on |
1 g |
$280.00 |
| |
the growth of various human hepatoma cell lines and stimulates the expression of p53 and p21. |
|
|
| |
Huang, X. Cancer Biology & Therapy (2008), 7(3), 468-475 |
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|
| |
Wu, Y. Life Sciences (2007), 81(17-18), 1332-1338. |
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| |
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|
| E5202 |
Enalapril |
1 g |
$34.50 |
| |
C20H28N2O5 FW 376.45 [75847-73-3] |
5 g |
$138.00 |
| |
An antihypertensive agent known to reduce the incidence of vascular dementia |
|
|
| |
and Alzheimer's disease. Found to have a potential for colon cancer prevention. |
|
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| |
Frishman WH. Heart Dis. 4:380-6 (2002). |
|
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| |
Yasumaru M et al. Cancer Res. 63:6726-34 (2003). |
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| |
|
|
|
| E5201 |
Enalapril Maleate |
1 g |
$38.10 |
| |
C20H28N2O5.C4H4O4 FW 492.52 [76095-16-4] |
5 g |
$151.90 |
| |
An angiotensin-converting enzyme inhibitor. It actively interferes with the renin-angiotensin- |
|
|
| |
aldosterone system. |
|
|
| |
Cleary JD, Taylor JW. Drug Intel Clin. Pharm. 20:177-186 (1986). |
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| |
|
|
|
| E5200 |
Enalaprilat |
10 mg |
$68.40 |
| |
C18H24N2O5.2H2O FW 384.42 [76420-72-9] |
50 mg |
$296.10 |
| |
The active metabolite of enalapril. |
100 mg |
$546.40 |
| |
Shioya H, Shimojo M, Kawahara Y. Biomedical Chromatography 6:59-62 (1992). |
|
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| |
|
|
|
| E5210 |
Endomorphin-1 |
5 mg |
$136.20 |
| |
C34H38N6O5 FW 610.72 |
10 mg |
$231.20 |
| |
An endogenous µ-opioid receptor agonist which has potent analgesic and |
25 mg |
$408.60 |
| |
gastrointestinal effects. |
|
|
| |
Somogyvari-Vigh, A. et al. Exp. Brain Res. 156:224 (2004). |
|
|
| |
Zadina, J. et al. Ann. NY. Acad. Sci. 897:136 (1999). |
|
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| |
|
|
|
| E5211 |
Endomorphin-2 |
5 mg |
$134.40 |
| |
C32H37N5O5 FW 571.68 |
10 mg |
$231.20 |
| |
|
25 mg |
$408.60 |
| |
|
|
|
| E5212 |
Endonuclease Antigenic Site |
1 mg |
$179.20 |
| |
C108H167N27O29 FW 2307.67 |
2 mg |
$304.60 |
| |
|
5 mg |
$537.60 |
| |
|
|
|
| E5214 |
a-Endorphin |
1 mg |
$64.50 |
| |
C77H120N18O26S FW 1745.98 |
2 mg |
$109.30 |
| |
a-endorphin is 1-16 fragment of a-endorphin. It binds to neuronal opiate |
5 mg |
$193.50 |
| |
receptors and has a stimulatory effect on immune system. |
|
|
| |
Waterfield, A. A. Eur. J. Pharmacol. 58:11 (1979). |
|
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| |
|
|
|
| E5215 |
Acetyl, a-Endorphin |
1 mg |
$71.70 |
| |
C79H122N18O27S FW 1788.02 |
2 mg |
$121.90 |
| |
|
5 mg |
$215.00 |
| |
|
|
|
| E5216 |
a-Endorphin, camel |
1 mg |
$164.90 |
| |
C155H250N42O44S FW 3438.04 |
2 mg |
$279.60 |
| |
|
5 mg |
$494.60 |
| |
|
|
|
| |
|
|
|
| E5217 |
a-Endorphin, human |
1 mg |
$107.50 |
| |
C158H251N39O46S FW 3465.06 |
2 mg |
$182.80 |
| |
|
5 mg |
$322.60 |
| |
|
|
|
| |
|
|
|
| E5218 |
a-Endorphin, rat |
1 mg |
$179.20 |
| |
C157H254N42O44S FW 3466.09 |
2 mg |
$304.60 |
| |
|
5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| E5219 |
Endothelin-1, human |
0.5 mg |
$358.40 |
| |
C109H159N25O32S5 FW 2491.95 |
1 mg |
$609.30 |
| |
It is produced by endothelial cells, neurons and astrocytes in the central |
2.5 mg |
$1,075.20 |
| |
nervous system, hepatocytes and Sertoli cells. It has an important role in the |
|
|
| |
paracrine regulation of cardiovascular functions in humans. |
|
|
| |
Yanagisawa, M. et al. Nature. 332:411 (1988). |
|
|
| |
|
|
|
| E5221 |
Endothelin-2, human |
0.5 mg |
$358.40 |
| |
C115H160N26O32S4 FW 2546.97 |
1 mg |
$609.30 |
| |
Mainly produced in the kidney and intestine. |
2.5 mg |
$1,075.20 |
| |
|
|
|
| |
|
|
|
| E5222 |
Endothelin-3, human |
0.5 mg |
$358.40 |
| |
C121H168N26O33S4 FW 2643.1 |
1 mg |
$609.30 |
| |
Mainly produced in the kidney and intestine. |
2.5 mg |
$1,075.20 |
| |
|
|
|
| |
|
|
|
| E5220 |
Enfuvirtide (T-20) |
1 mg |
$179.20 |
| |
C204H301N51O64 FW 4462.0 |
2 mg |
$304.60 |
| |
|
5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| E5240 |
Leu-Enkephalin |
25 mg |
$43.00 |
| |
C28H38N6O6 |
50 mg |
$73.50 |
| |
Leu-enkephalin has multiple effects on the central nervous system, including |
125 mg |
$129.00 |
| |
the neuroendocrine hypothalamus. It is an endogenous agonist for the receptors that are stimulated |
|
|
| |
by opiate alkaloids. |
|
|
| |
Dud‡s, B. and I. Merchenthaler et al. J. Clin. Endo. Met. 88:1842 (2003). |
|
|
| |
Zhang, N. et al. J. Biol. Chem. 278:12729 (2003). |
|
|
| |
|
|
|
| E5241 |
Met-Enkephalin |
25 mg |
$50.20 |
| |
C27H35N5O7S FW 573.67 |
50 mg |
$86.00 |
| |
|
125 mg |
$150.50 |
| |
|
|
|
| E2542 |
Met-Enkephalin, amide |
10 mg |
$37.60 |
| |
C27H36N6O6S FW 572.69 |
20 mg |
$62.70 |
| |
|
50 mg |
$111.10 |
| |
|
|
|
| E5456 |
Enocitabine |
25 mg |
$112.00 |
| |
C31H55N3O6 FW 565-78 [55726-47-1] |
100 mg |
$336.00 |
| |
Anti-tumor agent with suspected anti-leukemia potential treatment. |
250 mg |
$588.00 |
| |
Min, Woo-Sung. Hematological Oncology (2007), 25(2), 76-83. |
|
|
| |
Tsurumi, H. Journal of Cancer Research and Clinical Oncology (2007), 133(8), 547-553 |
|
|
| |
Usuki, K. International Journal of Hematology (2007), 85(1), 59-69. |
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| |
|
|
|
| E5358 |
Enoxacin |
500 mg |
$42.70 |
| |
C15H17N4O3F.3/2H2O FW 320.32 [74011-58-8] |
1 g |
$68.90 |
| |
Quinolone antibacteral agent. Acts on DNA gyrase. |
|
|
| |
Yoshida H. Nakamura M, Bogaki M et al. Antimicrob Agents Chemother 37:839-45 (1993). |
|
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| |
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|
| |
Enoxolone (See 18 b-Glycyrrhetinic acid) |
|
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| |
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| |
|
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| E5369 |
Enrofloxacin |
5 g |
$55.10 |
| |
C19H22FN3O3 FW 359.39 |
10 g |
$86.10 |
| |
A plant fungicide and antibacterial agent. |
50 g |
$340.90 |
| |
Schroder J, J S Afr. Vet Assoc. 60:122-4 (1989). |
|
|
| |
|
|
|
| E5576 |
Entecavir |
1 mg |
$35.00 |
| |
C12H15N5O3 FW 277.28 [142217-69-4] |
5 mg |
$120.00 |
| |
An antiviral agent used in the treatment of hepatitis B. |
25 mg |
$400.00 |
| |
Yurdaydin, C. Expert Opinion on Pharmacotherapy (2008), 9(17), 3095-3109. |
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| |
|
|
|
| E5276 |
Enterostatin, human |
1 mg |
$37.60 |
| |
C21H86N3O6 FW 496.57 |
2 mg |
$62.70 |
| |
A pentapeptide released from the exocrine pancreas and gastrointestinal |
5 mg |
$111.10 |
| |
tract that regulates fat intake. It possesses anti-analgesic activities. |
|
|
| |
Takenaka Y, Nakamura F, Usui H et al. Peptides. 24:735-9 (2003). |
|
|
| |
Lin L, Thomas SR, Kilroy G et al. Am J Physiol Regul Integr Comp Physiol. 285:R321-8 (2003). |
|
|
| |
|
|
|
| E5277 |
Enterostatin, porcine, rat |
1 mg |
$37.60 |
| |
C25H4N8O8 FW 582.66 |
2 mg |
$62.70 |
| |
|
5 mg |
$111.10 |
| |
|
|
|
| E6231 |
(-)Epicatechin |
1 mg |
$29.20 |
| |
C15H14O6 FW 290.27 [490-46-0] |
5 mg |
$112.10 |
| |
Natural product from green tea. |
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| |
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| |
|
|
|
| E6232 |
(-)Epicatechin gallate |
1 mg |
$20.70 |
| |
C22H18O10 FW 442.37 [1257-08-5] |
5 mg |
$68.90 |
| |
Natural product from green tea, induces apoptosis. |
|
|
| |
|
|
|
| E6233 |
(-)Epigallocatechin |
1 mg |
$19.20 |
| |
C15H14O7 FW 306.27 [970-74-1] |
5 mg |
$68.90 |
| |
Natural product from green tea. |
|
|
| |
|
|
|
| |
|
|
|
| E6234 |
Epigallocatechin gallate |
25 mg |
$30.90 |
| |
EGCG |
50 mg |
$51.00 |
| |
C22H18O11 FW 458.37 [989-51-5] |
100 mg |
$89.60 |
| |
An active component of tea for the chemoprevention of cancer. An antioxidant that |
|
|
| |
acts as an anti-promoter of carcinogenesis, inhibits angiogenesis and induces apoptosis. |
|
|
| |
Bhimani RS, Troll W, Grunberger D, Frenkel K. Cancer Res. 53:4528-4533 (1993). |
|
|
| |
Fujiki H, Suganuma M, Komori A et al. Cancer Detect. Prev.18: 1-7 (1994). |
|
|
| |
Dong Z, Ma W, Huang C, Yang CS. Cancer Res. 57:4414-4419 (1997). |
|
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| |
|
|
|
| E6432 |
(-)-Epinephrine |
1 g |
$20.70 |
| |
Adrenalin; L-Adrenaline; L-Epinephrine |
5 g |
$55.20 |
| |
C9H13NO3 FW 183.20 [51-43-4] |
10 g |
$96.70 |
| |
A predominent neurotransmitter. Found to be effective beta2-agonist |
100 g |
$482.90 |
| |
bronchodilator. |
|
|
| |
King Vj et al.Arch Pediatr Adolesc Med.158:127-37 (2004). |
|
|
| |
Rosol TJ, Yarrington JT, Latendresse J, Capen CC..29:41-8 (2001). |
|
|
| |
|
|
|
| E6235 |
Epirubicin hydrochloride |
1 mg |
$53.00 |
| |
4'-Epidoxorubicin hydrochloride, Farmorubicin, pharmorubicin |
5 mg |
$223.70 |
| |
C27H29NO11.HCl FW 579.99 [56390-09-1] |
10 mg |
$376.20 |
| |
An analog of doxorubicin. |
|
|
| |
|
|
|
| E6259 |
Epoxiconazole |
5 g |
$39.20 |
| |
C17H13ClFN3O FW 329.76 [106325-08-0] |
10 g |
$50.40 |
| |
A pesticide which has been classified by the EPA likely to be carcinogenic to |
100 g |
$296.80 |
| |
humans based on evidence of hepatic tumors. |
|
|
| |
Mazur, C. S. Environmental Science & Technology (2008), 42(3), 947-954. |
|
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| |
|
|
|
| E6470 |
Eprinomectin |
100 mg |
$75.30 |
| |
B1a R=C2H5 C50H75NO14 FW 914.13 [133305-88-1] |
250 mg |
$125.40 |
| |
B1b R=CH3 C49H73NO14 FW 900.10 [133305-89-2] |
1 g |
$401.40 |
| |
An insecticide commonly used as a topical anthelmintic. |
|
|
| |
Lespine A, Sutra JF, Dupuy J et al. Parasitol Res. 89:120-2 (2003). |
|
|
| |
Chartier C, Pors I. Vet Parasitol. 125:415-9 (2004). |
|
|
| |
|
|
|
| E6376 |
Eptifibatide |
5 mg |
$179.20 |
| |
Integrilin |
10 mg |
$304.60 |
| |
C35H49N11O9S2 FW 832.4 [148031-34-9] |
25 mg |
$537.60 |
| |
A selective inhibitor of platelet glycoprotein IIb/IIIa receptors. |
|
|
| |
Plosker Gl, Ibbotson T. Pharmacoeconomics. 21:885-912 (2003). |
|
|
| |
|
|
|
| E6781 |
(±)-Equol |
10 mg |
$72.80 |
| |
(R,S)-Equol; 3,4-Dihydro-3,(4-hydroxyphenyl)-2H-1-benzopyran-7-ol; 4',7 |
25 mg |
$140.00 |
| |
Dihydroxyisoflavane |
100 mg |
$364.00 |
| |
C15H14O3 FW 242.27 [94105-90-5] |
|
|
| |
Is an isoflavinoid metabolized from diadzein by bacterial flura in the intestines. |
|
|
| |
Equol may have beneficial effects on the incidence of prostatic cancer. It functions |
|
|
| |
as a DHT blocker and preferentially activates estrogen receptor type B. |
|
|
| |
Moors S. Molecular nutrition & food research (2007), 51(7), 787-98. |
|
|
| |
Tonetti D. A. Nutrition and cancer (2007), 58(2), 222-9. |
|
|
| |
Jackman K. A. Current medicinal chemistry (2007), 14(26), 2824-30 |
|
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| |
|
|
|
| E6814 |
Erdosteine |
100 mg |
$43.10 |
| |
C8H11NO4S2 FW 249.31 [84611-23-4] |
500 mg |
$112.10 |
| |
A homocysteine-derived expectorant. It undergoes metabolic conversion to |
1 g |
$186.00 |
| |
produce a thiol containing compound that has mucolytic and free radical scavenging activity. |
|
|
| |
Dechant KL, Noble S. Drugs 52:875-81 (1996). |
|
|
| |
Hosoe H, Kaise T, Ohmori K. J Pharm Pharmacol 51:959-66 (1999). |
|
|
| |
|
|
|
| E6824 |
Ergocalciferol |
10 mg |
$35.00 |
| |
C29H46O FW 410.67 [50-14-6] |
100 mg |
$95.00 |
| |
A form of Vitamin D, also called vitamin D2. |
500 mg |
$345.00 |
| |
Heaney, R. P. Clinical Journal of the American Society of Nephrology (2008), 3(5), 1535-1541. |
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| E6825 |
Ergosterol |
5 g |
$43.90 |
| |
C28H44O FW 396.65 [57-87-4] |
10 g |
$75.30 |
| |
A membrane lipid found almost exclusively in fungi. It is used as an indicator |
25 g |
$150.50 |
| |
of living fungal biomass. |
100 g |
$495.50 |
| |
Mille-lindblom C, von Wachenfeldt E, Tranvik LJ. J Microbiol Methods. 59:253-62 (2004). |
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Kasparovsky T, Blein JP, Mikes V. Plant Physiol Biochem. 42:429-35 (2004). |
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| E6846 |
Erlotinib Hydrochloride |
10 mg |
$67.20 |
| |
C22H23N3O4.HCl FW 429.9 [183319-69-9] |
25 mg |
$112.00 |
| |
The hydrochloride salt of a quinazoline derivative with anti-neoplastic |
100 mg |
$336.00 |
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properties. Competes with ATP, Erlotinib reversibly binds to EGFR tyroside kinase |
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which blocks the signal transduction events and tumorigenic events associated with EGFR activation. |
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Ali, S. Molecular Cancer Therapeutics (2008), 7(6), 1708-1719. |
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Rudin, C. M. Journal of Clinical Oncology (2008), 26(7), 1119-1127. |
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Burris, H. Oncologist (2008), 13(3), 289-298. |
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| E6880 |
Erucin |
25 mg |
$73.00 |
| |
C6H11NS2 FW 161.29 [4430-36-8] |
50 mg |
$126.70 |
| |
|
100 mg |
$216.60 |
| |
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| E6896 |
Erysolin |
25 mg |
$96.10 |
| |
C6H13NO2S2 FW 193.29 [504-84-7] |
50 mg |
$160.30 |
| |
|
100 mg |
$288.30 |
| |
|
500 mg |
$971.50 |
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| E6994 |
Erythromycin |
5 g |
$37.60 |
| |
C37H67NO13 FW 733.93 [114-07-8] |
25 g |
$106.60 |
| |
Erythromycin is a macrolide antibiotic, found to exert anti-inflammatory effect. |
100 g |
$332.40 |
| |
It inhibits NF-kappaB DNA binding activities, IL-8 NF-kappaB transcription, |
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and CYP3A4/5. |
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Aoki Y, Kao PN. Antimicrob Agents Chemother. 43:2678-84 (1999). |
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Tran JQ, Di Cicco RA, Sheth SB et al. J Clin Pharmacol. 39:513-9 (1999). |
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| E6995 |
Erythromycin Ethylsuccinate |
5 g |
$37.60 |
| |
C43H75NO16 FW 862.05 [41342-53-4] |
25 g |
$106.60 |
| |
|
100 g |
$332.40 |
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| E6996 |
Erythromycin Thiocyanate |
25 g |
$89.70 |
| |
C37H67NO13HSCN FW 793.0 [7704-67-8] |
100 g |
$276.00 |
| |
An antimicrobial agent. |
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Vanhaecke E, De Backer P, Remon JP, Devriese LA. J Vet Pharmacol Ther. 13:356-60 (1990). |
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| E6993 |
Erythromycin resistance peptide MRLFV |
1 mg |
$37.60 |
| |
C31H52N8O6S FW 664.86 |
2 mg |
$62.70 |
| |
|
5 mg |
$111.10 |
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| E6997 |
Erythropoietin |
50 U |
$604.40 |
| |
Human, Recombinant, Ultra Pure |
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Key regulator of erythroid blood cell proliferation and differentiation. It induces p21ras |
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activation and p120GAP tyrosine phosphorylation in human erythroleukemia cells. |
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Torti M, Marti KB, Altschuler D et al. J Biol Chem. 267:8293-8 (1992). |
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Wuelle FW, Wojchowski DM. J biol Chem. 266:609-14 (1991). |
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| E7309 |
Esculetin |
500 mg |
$57.70 |
| |
C9H6O4 FW 178.14 [305-01-1] |
1 g |
$92.40 |
| |
A lipoxygenase inhibitor. Potent chemopreventive agent capable of reducing oxidative |
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stress in liver, inhibiting carcinogen DNA binding in human bronchial epithelial cells |
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and inducing reduced glutathione in buffalo and rat liver cells. |
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Matsunaga K, Yoshimi N, Yamada Y et al. Jpn J Cancer Res. 89:496-501 (1998). |
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Lin WL, Wang CJ, Tsai YY et al. Arch Toxicol.74:467-72 (2000). |
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Sharma S, Stutzman JD, Kelloff GJ, Steele VE. Cancer Res. 54:5848-55 (1994). |
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| E7310 |
Esculin |
5 g |
$44.80 |
| |
C15H16O9 FW 340.28 [531-75-9] |
10 g |
$72.80 |
| |
A naturally occuring antioxidant. It inhibits chemically induced carcinogenesis in |
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the mouse skin and kidney. |
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Van Duren BL, Goldschmidt BM. J Natl Cancer Inst. 56:1237-42 (1976). |
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Imaida K, Hirose M, Yamaguchi S et al. Cancer Lett. 55:53-9 (1990). |
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| E7357 |
Esomeprazole potassium |
25 mg |
$66.30 |
| |
C17H19N3O3S FW 345.42 |
100 mg |
$186.40 |
| |
A proton pump inhibitor. Used as an antiulcerative agent. |
500 mg |
$758.90 |
| |
Garnett WR. Ann Pharmacother. 30:1425-36 (1996). |
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| E7376 |
Estradiol |
1 g |
$30.50 |
| |
|
5 g |
$124.20 |
| |
Potent mammalian estrogenic hormone useful in the prevention of neuro- |
25 g |
$407.10 |
| |
degenerative diseases such as Alzheimer's and Parkinson disease, in both men |
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| |
and women. Found to be major steroid mitogen in premenopausal women. |
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| |
Bhavnani BR. J Steroid Biochem Mol Biol. 85:473-82 (2003). |
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| E7377 |
Estriol |
100 mg |
$27.70 |
| |
C18H24O3 FW 288.38 [50-27-1] |
500 mg |
$69.00 |
| |
Estradiol metabolite was found to prevent bone loss in osteoporotic rats and |
1 g |
$117.40 |
| |
post menopausal women. Provides protection against mammary carcinogenisis |
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| |
and urogenital tract aging. |
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| |
Rajkumar L, Guzman RC, Yang J et al. Breast Cancer Res. 6:R31-7 (2004). |
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Luo XH, Liao EY. Endocr Res. 29:343-51 (2003). |
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Dessole S et al. Menopause. 11:49-56 (2004). |
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| E7378 |
Estrone |
1 g |
$24.90 |
| |
C18H22O2 FW 270.37 [53-16-7] |
5 g |
$99.50 |
| |
Estradiol metabolite found to reduce colon tumorigenesis in mice, |
25 g |
$414.00 |
| |
independently of ERalpha. Found to inhibit BCRP-mediated drug efflux and |
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| |
overcome drug resistance. |
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| |
Guo JY et al. J Nutr. 134:179-82 (2004). |
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Imai Y, Tsukahara S, Ishikawa E et al. Jpn J Cancer Res. 93:231-5 (2002). |
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| E7228 |
Ethacridine Lactate Monohydrate |
25 g |
$62.20 |
| |
Acrinol; ethodin; 6,9-Diamino-2-ethoxyacridine-DL-lactate monohydrate |
50 g |
$103.50 |
| |
C15H15N3O.C3H6O3.H2O FW 361.39 [6402-23-9] |
100 g |
$172.50 |
| |
An antiseptic agent found to be an effective abortifacient. |
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Bygdeman M. Clin Obstet Gynaecol. 11:573-84 (1984). |
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Gupta S, Sachdeva L, Gupta R. Indian J Matern Child Health. 4:59-61 (1993). |
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| E7230 |
Ethambutol |
25 g |
$103.50 |
| |
C10H24N2O2 FW 204.31 [74-55-5] |
100 g |
$276.00 |
| |
An antibacterial agent. |
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| |
Bernard EM, Edwards FF, Kiehn TE et al. Antimicrob Agents Chemother. 37:2323-6 (1993). |
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| E7324 |
Ethisterone |
1 g |
$20.70 |
| |
C21H28O2 FW 312.45 [434-03-7] |
5 g |
$41.40 |
| |
A progestogen that counteracts the estrogenic proliferative effect on the |
25 g |
$138.00 |
| |
endometrium. |
100 g |
$448.40 |
| |
Ferrero S, Gerbaldo D, Fulcheri E, Cristoforoni P. Minerva Ginecol. 54:519-30 (2002). |
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| E7329 |
Ethoxyquin |
100 g |
$48.00 |
| |
C14H19NO FW 204.29 [91-53-2] |
250 g |
$104.40 |
| |
A synthetic antioxidant that inhibits chemically induced carcinogenesis. It |
1 kg |
$339.00 |
| |
exerts its chemopreventive action by inducing glutathione synthetase, one of |
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| |
the enzymes in the synthesis of glutathione, and the phase II drug metabolizing enzyme, |
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| |
glutathione S-transferase (GST). |
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Shpherd AG, Manson MM, Ball Hw, Mclellan LI. Carcinogenesis. 21:1827-34 (2001). |
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Hayes JD, Mc Leod R, Ellis EM et al. IARC Sci Publ. 139:175-87 (1996). |
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| E7433 |
Etidronate Disodium |
1 g |
$57.50 |
| |
C2H6Na2O7P2 FW 249.99 [7414-83-7] |
5 g |
$229.50 |
| |
A bisphosphonate bone resorption inhibitor. |
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| E7556 |
Etodolac |
100 mg |
$47.70 |
| |
C17H21NO3 FW 287.35 [41340-25-4] |
250 mg |
$94.10 |
| |
A COX-2 inhibitor with anti-inflammatory and analgesic activity. It has been |
1 g |
$250.90 |
| |
shown to inhibit growth and PCNA expression and induce cell cycle arrest in human |
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| |
hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of aberrant |
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| |
crypt foci and tumors in colitis-induced tumorigenesis in rats. |
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Cheng J, Imanishi H, Liu W et al. Cancer Sci. 95:666-73 (2004). |
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Takeda J, Kitajima K, Fujii S et al. Oncol Rep. 11:981-5 (2004). |
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Lynch S, Brogden RN. Drugs. 31:288-300 (1986). |
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| E7657 |
Etoposide |
100 mg |
$98.60 |
| |
C29H32O13 FW 588.56 m.p. 236-2510C [33419-42-0] |
500 mg |
$394.00 |
| |
An anticancer agent, topoisomerase inhibitor, and apoptosis inducer. |
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Fearnhead JO. Biochem.Pharmacol. 48:1073-1079 (1994). |
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deJong RS, Chwalinski ., Snowden RT et al. Anticancer Res. 15:2319 (1995). |
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| E7668 |
Etretinate |
25 mg |
$50.40 |
| |
C23H30O3 FW 354.48 [54350-48-0] |
100 mg |
$140.00 |
| |
An aromatic retinoid used in treatment of severe psoriasis, lichen |
500 mg |
$448.00 |
| |
amyloidosus and keratotic genodermatosis. |
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| |
Helander I. Hopsu-Havu VK. Clin Exp Dermatol. 11: 574-77 (1986). |
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Brazzell, RK, Colburn, WA. J Am Acad Dermatol. 6: 643Đ651 (1982). |
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| E8129 |
Euphorbiasteroid |
10 mg |
$38.10 |
| |
C32H40O8 FW 552.66 |
25 mg |
$72.90 |
| |
Natural product isolated from Euphorbia lathyris L. |
100 mg |
$220.20 |
| |
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| E8657 |
Evodiamine |
100 mg |
$89.60 |
| |
C19H17N3O FW 303.36 [518-17-2] |
250 mg |
$168.00 |
| |
A non-pungent vanilloid receptor agonist isolated from Evodia rutaecarpa that |
1 g |
$504.00 |
| |
induces apoptosis in leukemic U937 cells. |
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| |
Kobayashi Y, Nakano Y, Kizaki M et al. Planta Med. 67:628-633 (2001). |
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| |
Lee TJ, Kim EJ, Kim S et al. Mol Cancer Ther. 5:2398-2407 (2006). |
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| E9317 |
Exemestane |
25 mg |
$57.80 |
| |
C20H24O2 FW 296.40 [107868-30-4] |
100 mg |
$159.50 |
| |
A steroidal aromatase inhibitor. |
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| |
Giudici, D. J. Steroid Biochem 30:391-394 (1988). |
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| E9416 |
Exendin-3 |
0.5 mg |
$279.60 |
| |
C184H282N50O61S FW 4202.66 |
1 mg |
$474.90 |
| |
|
2.5 mg |
$838.70 |
| |
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| E9417 |
Exendin-4 |
0.5 mg |
$279.60 |
| |
C184H282N50O60S FW 4186.03 |
1 mg |
$474.90 |
| |
|
2.5 mg |
$838.70 |
| |
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| E9418 |
Exendin (9-39) |
0.5 mg |
$358.40 |
| |
C149H234N40O47S FW 3369.83 |
1 mg |
$609.30 |
| |
|
2.5 mg |
$1,075.20 |
| |
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| E9819 |
Ezetimibe |
25 mg |
$50.40 |
| |
C24H21F2NO3 FW 409.43 [163222-33-1] |
100 mg |
$134.40 |
| |
Is an anti-hyperlipidemic medication used to lower cholesterol levels. It acts by |
250 mg |
$252.00 |
| |
inhibing the absorptioin of cholesterol from the diet. Specifically it bings to a |
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| |
critical mediator of cholesterol absorption (NPC1L1). |
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| |
Brown, B. New England Journal of Medicine (2008), 359(5), 532-533. |
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Maki-Petaja, K. Journal of the American College of Cardiology (2007), 50(9), 852-858. |
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