| I0502 |
Ibandronate |
50 mg |
$155.00 |
| |
C9H22NNaO7P2.H2O FW 359.21 |
100 mg |
$289.30 |
| |
A third generation bisphosphonate used as bone resorptive inhibitor. Found to enhance |
|
|
| |
the antitumor activity of taxol and docetaxol in bone metastasis. |
|
|
| |
Dooley M, Balfour JA. Drugs. 57:101-8 (1999). |
|
|
| |
Magnetto S, Boissier S, Delmas PD, Clezardin P. Int J Cancer. 83:263-9 (1999). |
|
|
| |
|
|
|
| I0416 |
Iberin |
10 mg |
$91.40 |
| |
C5H9NOS2 FW 163.26 [505-44-2] |
25 mg |
$215.30 |
| |
Homolog of sulforaphane. |
50 mg |
$344.40 |
| |
|
100 mg |
$602.60 |
| |
|
|
|
| I0418 |
Iberverin |
25 mg |
$73.00 |
| |
C5H9NS2 FW 147.26 [505-79-3] |
50 mg |
$126.70 |
| |
|
100 mg |
$216.60 |
| |
|
500 mg |
$732.70 |
| |
|
|
|
| I0480 |
Ibudilast |
10 mg |
$72.80 |
| |
C14H18N2O FW 230.31 [50847-11-5] |
25 mg |
$168.00 |
| |
An anti-inflammatory drug which acts as a phosphodiesterase inhibitor includig |
100 mg |
$560.00 |
| |
the POE-4. Know to have bronchodialator, vasodialator and neuroprotective effects. |
|
|
| |
Ledeboer, A. Expert Opinion on Investigational Drugs (2007), 16(7), 935-950. |
|
|
| |
|
|
|
| I0481 |
Ibuprofen |
1 g |
$28.10 |
| |
C13H18O2 FW 206.28 [15687-27-1] |
5 g |
$104.80 |
| |
Non-steroidal anti-inflammatory agent. It has undergone clinical |
10 g |
$192.20 |
| |
trials as a chemopreventive agent. |
|
|
| |
Kelloff GJ, Boone CW, Crowell JA, et al. Cancer Epidemiol. Biomarkers Prev. 3:85-98 (1994). |
|
|
| |
|
|
|
| I0482 |
S(+) Ibuprofen |
1 g |
$38.10 |
| |
Dexibuprofen |
5 g |
$136.60 |
| |
The optically active form of Ibuprofen. |
25 g |
$379.50 |
| |
|
|
|
| I0901 |
Icariin |
100 mg |
$75.90 |
| |
C33H40O15 FW 676.66 |
500 mg |
$280.90 |
| |
A flavonol glycoside isolated from Epimedium that has antihepatotoxic activity. It was found |
1 g |
$455.40 |
| |
to induce differentiatioin of HL-60 cells. |
|
|
| |
Lee MK, Choi YJ, Sung SH. Planta Medica 61:523-526 (1995). |
|
|
| |
Zhao Y, Cui Z, Zhang L. Chinese J Oncol.19:53-55 (1997). |
|
|
| |
|
|
|
| I1400 |
Idarubicin Hydrochloride |
1 mg |
$91.20 |
| |
C26H27NO9.HCl FW 533.96 [57852-57-0] |
5 mg |
$364.30 |
| |
It is a derivative of daunorubicin that has high antitumor activity against leukemia |
|
|
| |
and breast cancer. It induces apoptosis. |
|
|
| |
Ganzina F, Pacciarini MA, Di Pietro N. Invest New Drugs. 4:85-105 (1986). |
|
|
| |
Tsuruo T, Oh-Hara T, Sudo Y, Naito M. Anticancer Res. 13:357-61 (1993). |
|
|
| |
Belaud-Rotureau MA, Durrieu F, Labroille G et al. Leukemia. 14:1266-75 (2000). |
|
|
| |
|
|
|
| I1418 |
Idebenone |
10 mg |
$48.40 |
| |
C18H28O5 FW 324.41 [58186-27-9] |
25 mg |
$82.90 |
| |
Idebenone, a coenzyme Q analogue, is an antioxidant that prevents stroke and |
100 mg |
$289.90 |
| |
renal vascular lesions in hypertensive rats. Its protective effects involve the |
|
|
| |
redox cycling between its hydroquinone and quinone forms. |
|
|
| |
Mordente A, Martorana GE, Minotti G, Giardina B. Chem Res Toxicol. 11:54-63 (1998). |
|
|
| |
Nagaoka A, Shino A, Kakihana M, Iwatsuka H. Jpn J Pharmacol. 36:291-9 (1984). |
|
|
| |
|
|
|
| I1257 |
Idoxuridine |
500 mg |
$34.50 |
| |
5-Iodo-2"-deoxyuridine |
1 g |
$54.90 |
| |
C9H11IN2O5 FW 354.10 m.p. 164-1660C (dec.) [54-42-2] |
|
|
| |
A cytotoxic, anti-viral thymidine analog. |
|
|
| |
Pressacco J, Hedley DW, Erlichman C. Cancer Res. 54:3772-3778 (1994). |
|
|
| |
|
|
|
| I2056 |
Ifosfamide |
25 mg |
$80.60 |
| |
C8H17Cl2N2O2P FW 275.11 |
50 mg |
$134.40 |
| |
Cytostatic Agent |
|
|
| |
Ritter S, Schroder HJ. Medizinische Welt. 28:1395-1400 (1977). |
|
|
| |
Zalupski M, Baker LH. J Natl Cancer Inst. 80:556-566 (1988). |
|
|
| |
|
|
|
| I4000 |
Ikarugamycin |
0.5 mg |
$137.80 |
| |
C29H40N2O4 FW 480.64 |
1 mg |
$249.80 |
| |
An antiprotozoal antibiotic found to inhibit cholesteryl ester accumulation in |
5 mg |
$1,032.60 |
| |
macrophage. Shown to be an efficient inhibitor of clathrin-coated pits-dependent endocytosis. |
|
|
| |
Jomon K, Kuroda Y, Ajisaka M, Sakai H. J Antibiot (Tokyo). 25:271-80 (1972). |
|
|
| |
Hasumi K, Shinohara C, Naganuma S, Endo A. Eur J Biochem. 205:841-6 (1992). |
|
|
| |
Luo T, Fredericksen BL, Hasumi K et al. I Virol. 75:2488-92 (2001). |
|
|
| |
|
|
|
| I5072 |
Imazalil |
5 g |
$39.20 |
| |
C14H14Cl4N2O FW 297.18 [35554-44-0] |
10 g |
$50.40 |
| |
A pesticide with carcinogenic potential. |
100g |
$296.80 |
| |
Smilanick, J. Postharvest Biology and Technology (2008), 47(2), 226-238 |
|
|
| |
|
|
|
| |
|
|
|
| I4934 |
Imipenem |
25 mg |
$67.20 |
| |
C12H17N3O4S FW 299.349 [64221-86-9] |
100 mg |
$196.00 |
| |
Imipenem is a potent third generation cephalosporin often used as a post |
500 mg |
$560.00 |
| |
operative anti-biotic. It has recently shown promise in fighting increasingly more |
|
|
| |
resistant strains of staphylococcus aureus. |
|
|
| |
Morimoto Y, Sugiura T, Tatebayashi S, Kirita T. Spec Care Dentist. 26:209-13 (2006). |
|
|
| |
|
|
|
| I5034 |
Imiquimod |
100 mg |
$62.20 |
| |
C14H16N4 FW 240.30 [99011-02-6] |
500 mg |
$117.40 |
| |
An immune response modifier that induces a-interferon in numerous species |
1 g |
$207.00 |
| |
including human. It inhibits colon and lung tumors in mice and has antiviral |
5 g |
$724.40 |
| |
activity against HSV-2 infection. Its antitumor activity is related to the induction of apoptosis. |
|
|
| |
Sidky YA, Borden EC, Weeks CE et al. Cancer Res. 52:3528-33 (1992). |
|
|
| |
Bernstein DI, Harrison CJ. Antimicrob Agents Chemotgher. 33:1511-5 (1989). |
|
|
| |
Gibson SJ, Lindh JM, Riter TR et al. Cell Immunol. 218:74-86 (2002). |
|
|
| |
Schon M, Bong AB, Drewniok C et al. J Natl Cancer Inst. 95:1138-49 (2003). |
|
|
| |
|
|
|
| |
Incadronate Disodium |
|
|
| |
(See Disodium Cycloheptylaminomethylene Diphosphonate) |
|
|
| |
|
|
|
| I5414 |
Indapamide |
250 mg |
$38.60 |
| |
C6H16ClN3O3S FW 365.84 [26807-65-8] |
1 g |
$52.50 |
| |
An antihypertensive agent that reduces intracellular calcium levels, maintains |
5 g |
$172.50 |
| |
magnesium ion but reduces phosphate ions involved in arterial rigidity and many other functions. |
|
|
| |
Campbell DB, Brackman F. Am J Cardiol. 65:11H-27H (1990). |
|
|
| |
|
|
|
| I5213 |
Indole-3-carbinol |
5 g |
$56.00 |
| |
3-Indolemethanol |
25 g |
$228.90 |
| |
C9H9NO FW 147.18 m.p. 96-980C [700-06-1] |
|
|
| |
A component of cruciferus vegetables. Found to be effective against |
|
|
| |
chemically induced carcinogenesis. |
|
|
| |
Grubbs CJ, Steele VE, Casebolt T et al. Anticancer Res. 15:709-716 (1995). |
|
|
| |
|
|
|
| I5215 |
Indolicidin |
0.5 mg |
$107.50 |
| |
C100H132N26O13 FW 1906.33 |
1 mg |
$182.80 |
| |
An antimicrobial peptide containing multiple tryptophan residues. |
2.5 mg |
$322.60 |
| |
Selsted ME, Novotny MJ, Morris WL et al. J Biol Chem. 267:4292-4295 (1992). |
|
|
| |
|
|
|
| I5315 |
Indomethacin |
5 g |
$27.70 |
| |
C19H16ClNO4 FW 357.79 [53-86-1] |
10 g |
$48.40 |
| |
A non-steroidal anti-inflammatory agent which inhibits the activity of |
25 g |
$82.90 |
| |
cyclooxygenase and the induction of ornithine decarboxylase. It has cancer |
100 g |
$186.40 |
| |
chemopreventive activity and induces apoptosis. |
|
|
| |
Verma AK, Ashendel CL, Boutwell RK. Cancer Res. 40:308-315 (1980). |
|
|
| |
Grubbs CJ, Juliana MM, Eto I et al Anticancer Res. 13:33-6 (1993). |
|
|
| |
Tanaka T, Suzui M, Kojima T et al. Cancer Detection Prev. 19:418-25 (1995). |
|
|
| |
Zhou XM, Wong BC, Fan XM et al. Carcinogenesis. 22:1393-7 (2001). |
|
|
| |
|
|
|
| I5357 |
Inositol |
100 g |
$34.50 |
| |
C6H12O6 FW 180.16 [87-89-8] |
500 g |
$133.50 |
| |
Is an essentially non toxic compound largely formed by the dephosphorylation of inositol |
|
|
| |
hexaphosphate (IP6, Phytate) within the gastrointestinal tract in humans and animals. It |
|
|
| |
reduces chemically induced lung tumor formation in experimental animals when administered |
|
|
| |
after carcinogen treatment. It also suppresses liver carcinogenesis in male C3H/He mice. |
|
|
| |
Wattenberg LW, Anticancer Res. 19:3659-61 (1999). |
|
|
| |
Hecht SS, Kenney PM, Wang M et al. Cancer Lett.137:123-30 (1999). |
|
|
| |
Nishino H, Murakoshi M et al. Anticancer Res. 19:3663-64 (1999). |
|
|
| |
|
|
|
| |
Inositol hexaphosphate (See Phytic acid) |
|
|
| |
|
|
|
| I5476 |
Interleukin-6 Receptor (partial) |
0.5 mg |
$71.70 |
| |
C51H85N13O21 FW 1216.32 |
1 mg |
$121.90 |
| |
|
2.5 mg |
$215.00 |
| |
|
|
|
| I5830 |
Iohexol |
1 g |
$41.40 |
| |
C19H26I3N3O9 FW 821.14 [66108-95-0] |
5 g |
$176.60 |
| |
A non-ionic contrast agent. |
25 g |
$689.90 |
| |
Wieslander JB, Stjernquist U. Acta Radiol Suppl. 370:73-7 (1987). |
|
|
| |
|
|
|
| I5753 |
Ionomycin (Calcium Salt) |
1 mg |
$22.40 |
| |
C41H79O92-Ca FW 747.1 [56092-82-1] |
5 mg |
$67.20 |
| |
A calcium ionophore known for its antipoliferative effects. It inhibits growth of human bladder |
|
|
| |
cancer cells with alteration of Bcl-2 and Bax expression levels. An apoptosis inducer. |
|
|
| |
Miyake H, Hara I, Yamanaka K, Arakawa S, Kamidono S. J Urology. 162:916-21 (1999). |
|
|
| |
Aagaard-Tillery KM, Jelinek DF. J Immunology. 155:3297-107 (1995). |
|
|
| |
|
|
|
| I6068 |
Ipriflavone |
1 g |
$77.60 |
| |
C18H16O3 FW 280.32 |
5 g |
$318.50 |
| |
A synthetic phytoestrogen used as preventative in bone loss. Shown to enhance |
10 g |
$513.00 |
| |
calcium transport. |
|
|
| |
Arjmandi BN, Khalil DA, Hollis BW. Calc Tiss Int. 67:225-9 (2000). |
|
|
| |
Glazier MG, Bowman MA. Arch Int Med. 161:1161-72 (2001). |
|
|
| |
|
|
|
| I6933 |
Irinotecan |
5 mg |
$155.00 |
| |
C33H38N4O6.HCl.3H2O FW 677.20 [136572-09-3] |
10 mg |
$275.40 |
| |
A member of the camptothecin drug family, and an inhibitor of the nuclear |
25 mg |
$430.40 |
| |
enzyme topoisomerase I which is involved in cellular DNA replication and transcription. |
|
|
| |
During replication Topoisomerase I mediates the relaxation of super coiled DNA, and its |
|
|
| |
inhibition results in breakage replication of the DNA chain and likely induces apoptosis. |
|
|
| |
Irinotecan is therefore an attractive target for anticancer drug development. Currently it is used for |
|
|
| |
the treatment of small cell lung cancer and advanced colorectal cancer. |
|
|
| |
Kellner U, Rudolph P, Parwaresch R. Onkologie. 23:424-430 (2000). |
|
|
| |
Kalemkerian GP, Worden FP. Expert Opin Investing Drugs. 9:565-79 (2000). |
|
|
| |
Saltz LB. Curr Oncol Rep. 1:155-160 (1999). |
|
|
| |
|
|
|
| I7074 |
Irsogladine Maleate |
100 mg |
$55.20 |
| |
C9H7Cl2N5.C4H4O4 FW 372.17 [84504-69-8] |
500 mg |
$172.50 |
| |
An anti-gastric ulcer agent that facilitates gap-junctional intercellular |
1 g |
$276.00 |
| |
communication through M1 muscarininc acetylcholine receptor binding. It is a |
|
|
| |
potent inhibitor of angiogenesis and protects MNNG-induced gastric carcinogenesis in rats. |
|
|
| |
Ueda F, Ban K, Ishima T. J Pharmacol Exp Ther. 274:815-9 (1995). |
|
|
| |
Sato Y, Morimoto A, Kiue A et al. FEBS Lett. 322:155-8 (1993). |
|
|
| |
Ren CJ, Ueda F, Roses DF et al. J Surg Res. 77:126-31 (1998). |
|
|
| |
Sugie S, Okamoto K, Watanabe T et al. Toxicology. 166:53-61 (2001). |
|
|
| |
|
|
|
| I7302 |
Isatin |
100 g |
$62.20 |
| |
Indole-2,3-dione |
500 g |
$276.00 |
| |
C8H5NO2 FW 147.13 [91-56-5] |
|
|
| |
An endogenous monoamine oxidase inhibitor that is involved in stress and anxiety. It is |
|
|
| |
an inhibitor of alkaline phosphatase, nitric oxide (NO)-stimulated soluble guanylate |
|
|
| |
cyclase, and other enzymes. |
|
|
| |
Hamaue N. Yakugaku Zasshi. 120:352-62 (2000). |
|
|
| |
Singh B, Kumar P, Bansal RC et al. Enzyme. 23:22-8 (1978). |
|
|
| |
Medvedev A, Bussygyna O, Pyatakova N et al. Biochem Pharmacol. 63:763-6 (2002). |
|
|
| |
|
|
|
| I7341 |
Isoniazid |
5 g |
$12.50 |
| |
C6H7N3O FW 137.14 [54-85-3] |
50 g |
$15.10 |
| |
A front-line antituberculosis agent. It generates nitric oxide when activated by |
100 g |
$22.60 |
| |
KatG, and has been shown to be a strong inhibitor of DPH metabolism. |
|
|
| |
Timmins GS, Master S, Rusnak F et al. J Bacteriol. 186:5427-31 (2004). |
|
|
| |
Kutt H. Epilepsia. 16:393-402 (1975). |
|
|
| |
|
|
|
| I7356 |
Isopropyl Thiogalactoside |
1 g |
$36.30 |
| |
C9H18O5S FW 238.30 [367-93-1] |
5 g |
$144.70 |
| |
An inhibitor of lac repressor, can modulate demethylation of the lac operator |
10 g |
$250.50 |
| |
DNA sites. |
|
|
| |
Iping GL, Thomas JT, Qinglin Ou, Chih-Lin Hsieh. MCB. 20:2343-2349 (2000). |
|
|
| |
|
|
|
| I7259 |
Isoproterenol Hydrochloride |
5 g |
$34.50 |
| |
Isoprenaline HCl |
25 g |
$103.50 |
| |
C11H17NO3.HCl FW 247.72 [51-30-9] |
100 g |
$310.50 |
| |
A b-adrenergic agonist. |
|
|
| |
|
|
|
| I7357 |
Isorhamnetin |
1 mg |
$232.40 |
| |
C16H12O7 FW 316.26 m.p. 3050C (dec.) |
5 mg |
$602.60 |
| |
A metabolite of quercetin. One of many flavonoids found in red wine. It inhibits |
|
|
| |
xanthine oxidase, which is implicated in oxidative damage to cells. Has anti-tumor promoting activity. |
|
|
| |
Burns J. Gardner PT, O'Neil J et al. J. Agric. Food Chem. 48:220-230 (2000). |
|
|
| |
Nagao A, Seki M, Kobayashi H. Biosci. Biotechnol. Biochem. 63:1787-1790 (1999). |
|
|
| |
Ito H, Miyake M, Nishitani E et al. Cancer Lett. 143:5-13 (1999) |
|
|
| |
|
|
|
| |
Isoquinolinesulfonyl-2-methylpiperazine (See H7) |
|
|
| |
|
|
|
| I7360 |
Isosorbide Mononitrate |
5 g |
$62.20 |
| |
C6H9NO6 FW 191.14 [16051-77-7] |
10 g |
$103.50 |
| |
A coronary vasodilator that does not require hepatic biotransformation. |
25 g |
$207.00 |
| |
Hayes PC, Westaby D, Williams R. Gut. 29:752-5 (1988). |
|
|
| |
|
|
|
| I7746 |
1-Isothiocyanato-7-(methylsulfenyl)-heptane |
10 mg |
$60.40 |
| |
7-Methylsulfenylheptyl isothiocyanate |
25 mg |
$129.20 |
| |
C9H17NS2 FW 203.37 |
50 mg |
$220.40 |
| |
An analog of erucin. |
|
|
| |
|
|
|
| I7447 |
1-Isothiocyanato-6-(methylsulfenyl)-hexane |
25 mg |
$77.60 |
| |
6-Methylsulfenylhexyl isothiocyanate |
50 mg |
$129.20 |
| |
C8H15NS2 FW 189.34 |
100 mg |
$215.30 |
| |
An analog of erucin. |
|
|
| |
|
|
|
| I7558 |
1-Isothiocyanato-9-(methylsulfenyl)-nonane |
25 mg |
$77.60 |
| |
9-Methylsulfenylnonyl isothiocyanate |
50 mg |
$129.20 |
| |
C11H21NS2 FW 231.42 |
100 mg |
$215.30 |
| |
A synthetic analog of erucin. |
|
|
| |
|
|
|
| I7359 |
1-Isothiocyanato-8-(methylsulfenyl)-octane |
25 mg |
$77.60 |
| |
8-Methylsulfenyloctyl isothiocyanate |
50 mg |
$129.20 |
| |
C10H19NS2 FW 217.40 |
100 mg |
$215.30 |
| |
An analog of Erucin. |
|
|
| |
|
|
|
| I7456 |
1-Isothiocyanato-7-(methylsulfinyl)-heptane |
10 mg |
$91.40 |
| |
7-Methylsulfinylheptyl isothiocyanate |
25 mg |
$215.30 |
| |
C9H17NOS2 FW 219.37 |
50 mg |
$344.40 |
| |
A synthetic compound that is present in watercress. |
100 mg |
$602.60 |
| |
Found to be a potent inducer of phase II enzymes |
|
|
| |
Peter R, Kathy F, Wary W, Richard M. Carcinogenesis. 21:1983-1988 (2000). |
|
|
| |
|
|
|
| I7457 |
1-Isothiocyanato-6-(methylsulfinyl)-hexane |
25 mg |
$109.00 |
| |
C8H15NOS2 FW 205.34 |
50 mg |
$181.20 |
| |
6-Methylsulfinylhexyl isothiocyante is a synthetic analogue of sulforaphane. |
100 mg |
$326.10 |
| |
|
|
|
| I7458 |
1-Isothiocyanato-9-(methylsulfinyl)-nonane |
25 mg |
$109.00 |
| |
9-Methylsulfinylnonnyl isothiocyanate |
50 mg |
$181.20 |
| |
C11H21NOS2 FW 247.42 |
100 mg |
$326.10 |
| |
A synthetic analouge of well known |
|
|
| |
phase II inducer sulforaphane. |
|
|
| |
|
|
|
| I7459 |
1-Isothiocyanato-8-(methylsulfinyl)-octane |
25 mg |
$109.00 |
| |
8-Methylsulfinyloctyl isothiocyanate |
50 mg |
$181.20 |
| |
C10H19NOS2 FW 233.40 |
100 mg |
$326.10 |
| |
A synthetic compound that is present in watercress. Found |
|
|
| |
to be a potent inducer of Phase II enzymes. |
|
|
| |
Peter R, Kathy F, Gary W, Richard M. Carcinogenesis. 21:1983-1988 (2000). |
|
|
| |
|
|
|
| I7556 |
1-Isothiocyanato-7-(methylsulfonyl)-heptane |
10 mg |
$60.40 |
| |
7-Methylsulfonylheptyl isothiocyanate |
25 mg |
$129.20 |
| |
C9H17NO2S2 FW 235.37 |
50 mg |
$220.40 |
| |
An analog of erysolin. |
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| I7557 |
1-Isothiocyanato-6-(methylsulfonyl)-hexane |
25 mg |
$99.90 |
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6-Methylsulfonylhexyl isothiocyanate |
50 mg |
$179.10 |
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C8H15NO2S2 FW 221.34 |
100 mg |
$306.50 |
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An analog of erysolin. |
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| I7658 |
1-Isothicyanato-9-(methylsulfonyl)-nonane |
25 mg |
$99.90 |
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9-Methylsulfonylnonyl isothiocyanate |
50 mg |
$179.10 |
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C11H21NO2S2 FW 263.42 |
100 mg |
$306.50 |
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A synthetic analog of erysolin. |
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| I7659 |
1-Isothicyanato-8-(methylsulfonyl)-octane |
25 mg |
$99.90 |
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8-Methylsulfonyloctyl isothiocyanate |
50 mg |
$179.10 |
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C10H19NO2S2 FW 249.40 |
100 mg |
$306.50 |
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An analog of Erysolin. |
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Isotretinoin (See 13-cis-retinoic acid) |
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| I7757 |
Itopride Hydrochloride |
1 g |
$62.20 |
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C20H26N2O4.HCl FW 394.88 [122892-31-3] |
5 g |
$255.40 |
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A gastroprokinetic benzamide derviative that inhibits acetylcholinesterase |
25 g |
$896.90 |
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reversibly. |
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Iwanaga Y, Kimura T, Miyashita N et al. Jpn J Pharmacol. 66:317-22 (1994). |
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| I7870 |
Itraconazole |
50 mg |
$32.90 |
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C35H38Cl2N8O4 FW 705.63 [84625-61-6] |
100 mg |
$57.50 |
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A triazole antifungal agent. |
250 mg |
$114.80 |
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Bailey EM, Krakovsky DJ, Rybak MJ. Pharmacother. 10:146-53 (1990). |
1 g |
$344.40 |
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| I8618 |
Ivermectin |
1 g |
$41.40 |
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B1a C48H74O14 FW 875.09 |
5 g |
$172.50 |
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B1b C47H72O14 FW 861.06 |
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An anthelmintic found to be a competitive inhibitor of specific [3H]-GABA binding site in |
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nematodes. It activates the glycine receptor chloride channel. |
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Ros-Moreno RM, Moreno-Guzman MJ, Jimenez-Gonzalez A et al. Parasitol Res. 85:320-3 (1999). |
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Shan Q, Haddrill JL, Lynch JW. J Biol Chem. 276:12556-64 (2001). |
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