| M0035 |
M35 |
0.5 mg |
$136.20 |
| |
C107H153N27O26 FW 2233.58 |
1 mg |
$231.20 |
| |
A chimeric peptide that acts as a Galanin receptor antagonist which evokes the |
2.5 mg |
$408.60 |
| |
acetylcholine in rats. |
|
|
| |
Ogren SO, Pramanik A, Land T, Lang U. Eur J Pharmacol 242(1) 59-64 (1993) |
|
|
| |
|
|
|
| M0040 |
M40 |
0.5 mg |
$136.20 |
| |
C94H145N23O24 FW 1981.34 |
1 mg |
$231.20 |
| |
A galanin receptor antagonist. |
2.5 mg |
$408.60 |
| |
Crawley JN, Robinson JK, Langel U, Bartfai T. Brain Research; 600(2): 268-272 (1993). |
|
|
| |
|
|
|
| M0114 |
Madecassic acid |
500 mg |
$88.10 |
| |
C30H48O6 FW 504.70 [18449-41-7] |
1 g |
$135.20 |
| |
One of the three triterpenes isolated from Centella asiatica. Its wound healing |
5 g |
$531.30 |
| |
property has been attributed to its abbility to stimulate collagen synthesis. |
|
|
| |
Maquart FX, Bellon G, Gillery P et al. Conn Tiss Res. 24:107-120 (1990). |
|
|
| |
Bonte F, Dumas M, Chaudagne C, Meybeck A. Plant Med. 60:133-135 (1994). |
|
|
| |
|
|
|
| M0124 |
Magainin 1 |
0.5 mg |
$78.80 |
| |
C112H177N29O28S FW 2409.9 |
1 mg |
$134.40 |
| |
An anti-microbial peptide shown to be active against many types of bacteria |
2.5 mg |
$236.50 |
| |
and protozoa. |
|
|
| |
Matsuzaki,Harada,Handa,Funakoshi,Fujii ,YajimaH,MiyajimaKBiochimBiophysActa981(1);130-4(1989) |
|
|
| |
Zasloff M, Martin B, Chen HC. PNAS 85(3) 910-913 (1988) |
|
|
| |
|
|
|
| M0126 |
Magainin 2 |
0.5 mg |
$43.00 |
| |
C114H180N30O29S FW 2466.95 |
1 mg |
$73.50 |
| |
An anti-microbial peptide that permeabilizes cell membranes. |
2.5 mg |
$129.00 |
| |
Matsuzaki k, Sugishita K, Ishibe N, Uzha M, Nakata S, Miyajima K, Epand R. |
|
|
| |
Biochemistry 37(34) 11856-11863 (1998). |
|
|
| |
|
|
|
| M0224 |
MAGE-3 Antigen (271-279), human |
1 mg |
$43.00 |
| |
C53H79N13O10 FW 1058.3 |
2 mg |
$73.50 |
| |
A human antigen that has been recognized to code for Melinoma and has also |
5 mg |
$129.00 |
| |
shown great promise for specific immunotherapy. |
|
|
| |
Gaglaou B et. al. J Experimental Medicine 179: 921-930 (1994). |
|
|
| |
|
|
|
| M0115 |
Magic RedTM Caspases 3 & 7 Assay Kit |
25 Tests |
$174.40 |
| |
MR-(DEVD)2 |
100 Tests |
$412.70 |
| |
|
|
|
| M0116 |
Magic RedTM Cathepsin B Assay Kit |
25 Tests |
$149.30 |
| |
MR-(RR)2 |
100 Tests |
$375.10 |
| |
|
|
|
| M0117 |
Magic RedTM Cathepsin K Assay Kit |
25 Tests |
$149.30 |
| |
MR-(LR)2 |
100 Tests |
$375.10 |
| |
|
|
|
| M0118 |
Magic RedTM Cathepsin L Assay Kit |
25 Tests |
$149.30 |
| |
MR-(FR)2 |
100 Tests |
$375.10 |
| |
|
|
|
| M0125 |
Magnolol |
10 mg |
$72.90 |
| |
C18H18O2 FW 266.33 [528-43-8] |
25 mg |
$154.90 |
| |
Natural product isolated from the cortex of Magnolia officinalis, has been found |
100 mg |
$494.90 |
| |
to possess many interesting biological activities. It has anti-allergic and |
|
|
| |
i anti-asthmatic activity, anti-nflammatory and neuroprotective effects, |
|
|
| |
anti-proliferative and activating apoptosis in cancer cells. |
|
|
| |
Lee MM, Huang HM, Hsieh, MT. Chinese J Physiology. 43:61-67 (2000). |
|
|
| |
Lin SY, Liu JD, Chang HC et al. J Cell Biochem. 84:532-544 (2002). |
|
|
| |
Lin SY, Chang YT, Liu JD et al. Mol Carcinogenesis. 32:73-83 (2001). |
|
|
| |
Wu Sn, Chen CC, Li HF et al. Thorax 57:67-74 (2002). |
|
|
| |
|
|
|
| M0144 |
Malantide |
1 mg |
$35.80 |
| |
C72H124N22O21 FW 1633.93 |
2 mg |
$60.90 |
| |
A cAMP synthetic peptide that performs protein kinase activity. |
5 mg |
$107.50 |
| |
MurrayK,England,LynhamJMillsD,Schmitz-peiferL,ReevesML.Biochem267(3):703-708 (1990). |
|
|
| |
|
|
|
| M0248 |
Manidipine Hydrochloride |
25 mg |
$44.80 |
| |
C35H36N4O6 FW 608.68 [89226-75-5] |
100 mg |
$112.00 |
| |
A third generation dihydropyridine calcium antagonist which casues systemic |
250 mg |
$207.20 |
| |
vasodilation by inhibiting the voltage dependent calcium inward currents in smooth |
|
|
| |
muscle cells. Hypertension drug. |
|
|
| |
Roth, M. American Heart Journal (1993), 125(2, Pt. 2), 598-603. |
|
|
| |
|
|
|
| M0262 |
Maprotiline Hydrochloride |
1 g |
$49.70 |
| |
C20H23N.HCl FW 313.87 [10347-81-6] |
5 g |
$158.70 |
| |
An antidepressant works as a selective noradrenaline reuptake inhibitor. It decreases |
|
|
| |
binding to 5HT2A receptors with no effect on benzodiazepine binding sites. |
|
|
| |
Pinder RM et al. Drugs 13:321 (1977). |
|
|
| |
|
|
|
| M0272 |
Mas7 |
1 mg |
$35.80 |
| |
C67H124N18O15 FW 1421.85 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| |
|
|
|
| M0273 |
Mas8 |
0.5 mg |
$35.80 |
| |
C70H131N21O15 FW 1506.96 |
1 mg |
$60.90 |
| |
|
2.5 mg |
$107.50 |
| |
|
|
|
| |
|
|
|
| M0275 |
Mas17 |
1 mg |
$35.80 |
| |
C70H132N20O15 FW 1493.96 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| |
|
|
|
| M0276 |
Mast Cell Degranulating Peptide |
0.5 mg |
$179.20 |
| |
C110H188N40O24S4 FW 2583.287 |
1 mg |
$304.60 |
| |
A highly potent convulsant polypeptide from the Mamba snake. |
2.5 mg |
$537.60 |
| |
Stansfeld CE, Marsh SJ, Parcej DN, Brown DA. Neuroscience 23(3) 893-902 (1987) |
|
|
| |
|
|
|
| M0172 |
Mastoparan |
1 mg |
$161.30 |
| |
C70H131N19O15 FW 1478.9 [72093-21-1] |
|
|
| |
A tetradecapeptide from wasp venom that activates G(i) and mast cells, in addition to |
|
|
| |
inhibiting Ca2+-ATPase. It has also been shown to induce apoptosis in cultured cerebellar |
|
|
| |
granule neurons. |
|
|
| |
Chahdi A, Choi WS, Kim YM et al. J Biol Chem. 278:12039-45 (2003). |
|
|
| |
Longland CL, Mezna M, Michelangeli F. J Biol Chem. 274 :14799-805 (1999). |
|
|
| |
Lin SZ, Yan GM, Koch KE et al. Brain Res. 771:184-95 (1997). |
|
|
| |
|
|
|
| M0173 |
Mastoparan X |
1 mg |
$43.00 |
| |
C73H126N20O15S FW 1556.01 |
2 mg |
$73.50 |
| |
A peptidic toxin known to induce transbilayer movement of ions. |
5 mg |
$129.00 |
| |
Matsuzaki K, Yoneyama S, Murase O, Miyajima K. Biochemistry 35(25); 8450-8456 (1996) |
|
|
| |
|
|
|
| M0278 |
Matrine |
100 mg |
$103.50 |
| |
C15H24N2O FW 248.36 [519-02-8] |
500 mg |
$379.50 |
| |
An alkaloid. It has antiulcerogenic activity against stress ulcer in rat. It |
1 g |
$586.40 |
| |
depresses both glutamate-induced responses and neurally evoked excitatory |
|
|
| |
junctional potentials. |
|
|
| |
Ishida M, Shinozaki H. Br J Pharmacol. 82:523-31 (1984). |
|
|
| |
Yamazaki M, Arai A. J Pharmacobiodyn. 8:513-7 (1985). |
|
|
| |
|
|
|
| M1605 |
Mebendazol |
5 g |
$27.70 |
| |
C16H13N3O3 FW 295.29 [31432-39-7] |
25 g |
$49.70 |
| |
An anthelmintic drug. |
|
|
| |
Apt W. Rev Med Chil. 118:1021-7 (1990). |
|
|
| |
|
|
|
| M1708 |
Mecamylamine Hydrochloride |
5 mg |
$30.80 |
| |
C11H21N.HCl FW 203.75 [826-39-1] |
25 mg |
$112.00 |
| |
Non-competitive nicotinic acetylcholine receptor antagonist; preferentially |
100 mg |
$358.40 |
| |
blocks nicotinic receptors at autonomic ganglia. Able to cross the blood brain barrier. |
|
|
| |
Rodgers, R. J. Psychopharmacology (Berlin, Germany) (1979), 66(1), 93-8. |
|
|
| |
|
|
|
| M1613 |
Medroxyprogesterone 17-Acetate |
500 mg |
$30.90 |
| |
C24H34O4 FW 386.52 [71-58-9] |
1 g |
$51.60 |
| |
An angiostatic steroid, found to inhibit vascularization, collagenolysis, |
5 g |
$198.20 |
| |
tumor growth and plasmin generation. |
|
|
| |
Blei F, Wilson EL, Mignatti P, Rifkin DB. J Cellu Physio. 155:568-78 (1993). |
|
|
| |
|
|
|
| M1622 |
Mefenamic acid |
10 g |
$22.80 |
| |
C15H15NO2 FW 241.29 [61-68-7] |
50 g |
$45.60 |
| |
A NSAID that has antiproliferative activity against human colon cancer cells. |
100 g |
$85.10 |
| |
Hixson LJ, Alberts DS, Krutzsch M et al. Cancer Epidem. Bio Prev. 3:433-438 (1994). |
|
|
| |
|
|
|
| M1626 |
Megestrol Acetate |
250 mg |
$36.10 |
| |
C24H32O4 FW 384.51 [595-33-5] |
1 g |
$98.60 |
| |
Orally active progestogen used in the treatment of advanced breast cancer. |
5 g |
$340.30 |
| |
Sbrams JS, Gutheil J, Aisner J. Oncology. 49 Suppl 2:12-7 (1992). |
|
|
| |
Sedlacek SM. Semin Oncol. 15:3-13 (1988). |
|
|
| |
|
|
|
| M1826 |
Meglumine |
100 g |
$38.60 |
| |
N-Methyl-D-glucamine |
500 g |
$117.40 |
| |
C7H7NO5 FW 195.20 [6284-40-8] |
1 kg |
$220.90 |
| |
An antiprotozoal (leischmaniasis) agent. |
|
|
| |
Chapman WL Jr, Hanson WL, Alving CR et al. Am J Vet Res. 45:1028-30 (1984). |
|
|
| |
|
|
|
| |
|
|
|
| M1646 |
Melanin Concentrating Hormone,human,mouse,rat |
0.5 mg |
$125.40 |
| |
MCH, human, mouse, rat |
1 mg |
$213.20 |
| |
C105H160N30O26S4 FW 2386.8 |
2.5 mg |
$376.30 |
| |
An orexigenic neuropeptide. It has been found to increase circulating adrenocorticotropic |
|
|
| |
hormone, hippocampal nitric oxide and cGMP levels. |
|
|
| |
Kennedy AR, Todd JF, Dhillo WS et al. J Neuroendocrinol. 15:268-72 (2003). |
|
|
| |
Varas M, Perez M, Monzon ME et al. Peptides. 23:2213-21 (2002). |
|
|
| |
|
|
|
| M1647 |
Melanin Concentrating Hormone, salmon |
0.5 mg |
$125.40 |
| |
MCH, salmon |
1 mg |
$213.20 |
| |
C89H137N27O24S4 FW 2097.9 |
2.5 mg |
$376.30 |
| |
|
|
|
| M7528 |
a-Melanocyte stimulating hormone |
1 mg |
$120.50 |
| |
C77H109N21O19S FW 1664.9 [581-05-5] |
|
|
| |
An endogenous peptide that exerts an anti-inflammatory action by inhibtion of nitric oxide synthase-2. |
|
|
| |
Gupta AK, Diaz RA, Higham S et al. Kidney International. 57:2239-2248 (2000). |
|
|
| |
|
|
|
| M7529 |
b-Melanocyte stimulating hormone, human |
1 mg |
$220.90 |
| |
C118H174N34O35S FW 2660.9 [17908-57-5] |
|
|
| |
The key ligand acting on melanocortin-4 receptors that play a part in the sensation of hunger. |
|
|
| |
Harrold JA, Widdowson PS, Williams G. Peptides. 24:397-405 (2003). |
|
|
| |
|
|
|
| M7530 |
[Nle4, D-Phe7] a-Melanocyte stimulating hormone |
5 mg |
$100.40 |
| |
NDP-MSH, Melanotan I |
25 mg |
$401.40 |
| |
C78H111N21O19 FW 1646.9 |
|
|
| |
|
|
|
| M7531 |
g 1-Melanocyte stimulating hormone |
1 mg |
$120.50 |
| |
C72H97N21O14S FW 1512.8 |
|
|
| |
|
|
|
| M7532 |
g 3-Melanocyte stimulating hormone |
1 mg |
$271.00 |
| |
C126H188N44O37S FW 2943.2 |
|
|
| |
|
|
|
| |
|
|
|
| M1649 |
Melanoma-associated antigen peptide |
1 mg |
$71.70 |
| |
MART-1(27-35), human |
2 mg |
$121.90 |
| |
C37H67N9O11 FW 814.0 |
5 mg |
$215.00 |
| |
|
|
|
| M1648 |
Melanostatin, frog |
0.5 mg |
$179.20 |
| |
C189H285N53O57S1 FW 4243.76 |
1 mg |
$304.60 |
| |
An alpha melanocyte stimulating horomone isolated from frogs brains. |
2.5 mg |
$537.60 |
| |
Valentijin JA, Vaudry H, Kloas W, Cazin L J Physiol 1175: 185-195 (1994). |
|
|
| |
|
|
|
| M1650 |
Melanotan II |
5 mg |
$107.50 |
| |
MT-II |
10 mg |
$182.80 |
| |
C50H69N15O9 FW 1024.2 [121062-08-6] |
25 mg |
$322.60 |
| |
A non selective melanocortin receptor agonist. It has been shown to increase insulin sensitivity |
|
|
| |
and exert neuroprotective effects in rat. |
|
|
| |
Banno R, Arima H, Sato I et al. Peptides. 25:1279-86 (2004). |
|
|
| |
Ter Laak MP, Brakkee JH, Adan RA et al. Eur J Pharmacol. 462:179-83 (2003). |
|
|
| |
|
|
|
| M1745 |
Melatonin |
1 g |
$61.90 |
| |
N-acetyl-5-methoxytryptamine |
5 g |
$255.40 |
| |
C13H16N2O2 FW 232.27 m.p. 116-1180C [73-31-4] |
10 g |
$456.40 |
| |
A hormone of the pineal gland, has antiproliferative and chemopreventive activity. It induces apoptosis. |
|
|
| |
Eck-Enriquez K, Kiefer TL, Spriggs LL, Hill SM. Breast Cancer Res Treat. 61:229-39 (2000). |
|
|
| |
Teplitzky SR, Kiefer TL, Cheng Q et al. Cancer Lett. 168:155-63 (2001). |
|
|
| |
Kothari A, Borges A, Kothari L. Eur J Cancer Prev. 4:497-500 (1995). |
|
|
| |
|
|
|
| M1744 |
Melittin |
0.5 mg |
$136.20 |
| |
Mellitin |
1 mg |
$231.20 |
| |
C131H229N39O31 FW 2846.5 [20449-79-0] |
2.5 mg |
$408.60 |
| |
A bee venom peptide that has been shown to inhibit viral infection development. |
|
|
| |
Lazarev VN, Stipkovits L, Biro J et al. Microbes Infect. 6:536-541 (2004). |
|
|
| |
|
|
|
| M1644 |
Meloxicam |
100 mg |
$70.90 |
| |
Metacam |
500 mg |
$211.30 |
| |
C14H13N3O4S2 FW 351.41 [71125-38-7] |
1 g |
$354.60 |
| |
A non-steroidal anti-inflammatory agent with high inhibitory action against the |
|
|
| |
inducible form of cyclo-oxygenase (COX-2). Found to inhibit the growth of |
|
|
| |
colorectal cancer cells in vitro. |
|
|
| |
Noble S, Balfour JA. Drugs. 51:424-430 (1996). |
|
|
| |
Goldman AP, Williams CS, Sheng H et al. Carcinogenesis 19:2195-2199 (1998). |
|
|
| |
|
|
|
| M1749 |
Memantine hydrochloride |
25 mg |
$45.60 |
| |
C12H21N.HCl FW 215.77 [41100-52-1] |
100 mg |
$129.10 |
| |
A non-competitive N-methyl-D-aspartate receptor antagonist. |
|
|
| |
Rammes G, Rupprecht R, Ferrari U et al. Neurosci. Letters. 306:81-84 (2001). |
|
|
| |
|
|
|
| M1752 |
Men 10376 |
0.5 mg |
$35.80 |
| |
C57H68N12O10 FW 1081.25 |
1 mg |
$60.90 |
| |
An NK2 antagonist. |
2.5 mg |
$107.50 |
| |
Ma QP, Woolf CJ. J Physiol 486: 769-777 (1995). |
|
|
| |
|
|
|
| M1669 |
6-Mercaptopurine Monohydrate |
5 g |
$66.50 |
| |
6-Purinethiol |
25 g |
$249.40 |
| |
C5H4N4S.H2O FW 170.20 m.p. 313-3140C [6112-76-1] |
|
|
| |
An anti-inflammatory agent that has antitumor activity. |
|
|
| |
Kela U, Vijayvargiya R. Biochem J. 193:799-803 (1981). |
|
|
| |
Bokkerink JP, Stet EH, De Abreu RA et al. Biochem Pharmacol. 45:1455-63 (1993). |
|
|
| |
|
|
|
| M1770 |
Meropenem |
25 mg |
$50.20 |
| |
C17H25N3O5S FW 383.46 [96036-03-2] |
100 mg |
$150.50 |
| |
An antibiotic, effective against a wide range of bacteria, that has a low |
500 mg |
$564.50 |
| |
toxicity profile and no central nervous system toxicity. |
|
|
| |
Cottagnoud P. Cell Mol Life Sci. 59:1928-33 (2002). |
|
|
| |
Kayser FH, Morenzoni G, Strassle A et al. J Antimicrob Chemother. 24 Suppl A:101-12 (1989). |
|
|
| |
|
|
|
| |
Mesalamine (See 5-Aminosalicylic acid) |
|
|
| |
Mesalazine |
|
|
| |
|
|
|
| M1774 |
MESNA (2-Mercaptoethanesulfonic Acid) |
5 g |
$41.20 |
| |
C2H6O3S2 FW 142.20 [3375-50-6] |
10 g |
$71.70 |
| |
A uroprotective agent used in combination with cancer chemotherapeutic drugs to |
25 g |
$152.20 |
| |
decrease urotoxicity. It was found to have antitumor activity against several cell lines. |
|
|
| |
In addition, it is used as an antimucolytic agent. |
|
|
| |
Brock N. Recent Results Cancer Res. 74:270-8 (1980). |
|
|
| |
Blomgren H, Hallstrom M, Hillgren H. Methods Find Exp Clin Pharmacol. 12:691-7 (1990). |
|
|
| |
Tekeres M, Horvath A, Bardosi L, Kenyeres P. Clin Ther. 4:56-60 (1981). |
|
|
| |
|
|
|
| M2076 |
Metformin Hydrochloride |
25 g |
$44.80 |
| |
1,1-Dimethylbiguanide Hydrochloride |
100 g |
$128.80 |
| |
C4H11N5.HCl FW 156.62 [1115-70-4] |
|
|
| |
An oral hyperglycemic drug utilized in the treatment of type 2 diabetes. |
|
|
| |
Decreases hepatitc glucose production, decreases intestinal absoption and increases insulin sensisivity. |
|
|
| |
Tucker, G. T. British Journal of Clinical Pharmacology (1981), 12(2), 235-46. |
|
|
| |
|
|
|
| M1976 |
Methimazole |
10 g |
$27.40 |
| |
C4H6N2S FW 114.17 [60-56-0] |
25 g |
$42.60 |
| |
Antithyroid compound used to treat Graves' hyperthyroidism. It was found to have antioxidant |
|
|
| |
property. It inhibits activation of the IFN-g-induced Janus kinase (JAK)/STAT signaling pathway |
|
|
| |
in FRTL-5 thyroid cells, which may account for its immunomodulatory effects. |
|
|
| |
Kim H, Lee TH, Hwang YS et al. Mol. Pharm. 60:972-980 (2001). |
|
|
| |
|
|
|
| M1676 |
Methotrexate |
10 mg |
$25.30 |
| |
C20H22N8O5 FW 454.44 [59-05-2] |
50 mg |
$44.20 |
| |
Antiinflammatory drug also used as antineoplastic agent. Inhibits dihydrofolate |
100 mg |
$81.10 |
| |
reductase. |
500 mg |
$465.00 |
| |
Eckardt, JR Anticancer Drugs. 7 Suppl 2:41-6 (1996). |
|
|
| |
Fleisher M. Ther Drug Monit. 15:521-6 (1993). |
|
|
| |
|
|
|
| M1680 |
5-Methoxyindole |
1 g |
$58.80 |
| |
C9H9NO FW 147.17 [1006-94-6] |
5 g |
$232.40 |
| |
|
|
|
| |
|
|
|
| M1677 |
11-Methoxyyangonin |
5 mg |
$111.40 |
| |
C16H16O5 FW 288.30 |
10 mg |
$172.10 |
| |
A component of kava kava extract. |
|
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| |
|
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|
| |
|
|
|
| M1776 |
a -Methylbenzyl isothiocyanate |
5 g |
$62.90 |
| |
C9H9NS FW 163.24 [32393-32-1] |
10 g |
$107.50 |
| |
|
|
|
| |
|
|
|
| M1777 |
R (-) a -Methylbenzyl isothiocyanate (D) |
1 g |
$36.10 |
| |
C9H9NS FW 163.24 [a]20D -21.16(neat) [24277-44-9] |
5 g |
$143.40 |
| |
Chiral agent. Used for the derivatization and separation of enantiomers. |
10 g |
$243.40 |
| |
Gal J, Sedman AJ. J Chromatography. 314:275-282 (1984). |
|
|
| |
Gal J, Desai DM, Meyer-Lehnert S. Chirality. 2:43-51 (1990). |
|
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| |
|
|
|
| M1778 |
S (+) a -Methylbenzyl isothiocyanate (L) |
1 g |
$35.10 |
| |
C9H9NS FW 163.24 [a]20D +28.14(neat) |
5 g |
$139.70 |
| |
Chiral derivatizing agent. |
10 g |
$232.80 |
| |
|
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|
| |
|
|
|
| M1560 |
Methyl Caffeate |
50 mg |
$53.50 |
| |
C10H10O4 FW 194.19 m.p. 163-1650C [3843-74-1] |
100 mg |
$83.60 |
| |
Inhibitor of ornithine decarboxylase and protein tyrosine kinase. |
500 mg |
$277.50 |
| |
Rao V, Desai, D, Kaul B et al. Chem Biol Interactions. 84:277-290 (1992). |
|
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| |
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| |
|
|
|
| M1565 |
S-Methyl-L-Cysteine-S-oxide |
100 mg |
$56.00 |
| |
C4H9NOsS FW 151.19 [6853-87-8] |
250 mg |
$112.00 |
| |
An analogue of alliin. |
1 g |
$336.00 |
| |
|
|
|
| |
|
|
|
| M1779 |
Methyldopa Sesquihydrate |
1 g |
$27.70 |
| |
C10H13NO.3/2H2O FW 238.24 [41372-08-1] |
5 g |
$55.20 |
| |
An adrenergic inhibiting agent is used in antihypertensive treatment. |
10 g |
$89.70 |
| |
Frohlich ED. Arch Intern Med. 140:954-9 (1980). |
|
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| |
|
|
|
| M1780 |
Methylhesperidin |
5 g |
$34.50 |
| |
C29H36O15 FW 624.59 [11013-97-1] |
25 g |
$110.40 |
| |
A vasodilating agent. |
|
|
| |
Kikuchi K. Hirata M. Imai Y. Aramaki Y. Jpn J Pharmacol. 16:224-5 (1966). |
|
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| |
Chen QM, Feng GH, Chung Kuo, Yao Li. Hsueh Pao. 8:344-8 (1987). |
|
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| |
|
|
|
| M1877 |
Methylprednisolone |
100 mg |
$48.40 |
| |
C22H30O5 FW 374.47 [83-43-2] |
500 mg |
$146.30 |
| |
Apoptosis inducer, used in the treatment of lupus nephritis. Found to inhibit |
1 g |
$249.80 |
| |
human small cell lung cancer cell growth. |
|
|
| |
Wang J, Lia H, Chen X, Chung Hua et al. Chinese Journal of Internal Medicine. 36:79-82 (1997). |
|
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| |
Yamaguchi S, Ohsaki Y, Nishigaki Y et al. Int J Oncol. 15:1185-90 (1999). |
|
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| |
|
|
|
| M1979 |
Methyl Salicylate |
250 mL |
$24.90 |
| |
C8H8O3 FW 152.15 [119-36-8] |
500 mL |
$41.40 |
| |
An anticoagulant in acts by interruption of the vitamin K1-epoxide cycle. |
1 L |
$69.00 |
| |
Park BK, Leck JB. J Pharm Pharmacol. 33:25-8 (1981). |
|
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| |
|
|
|
| M1679 |
Methysticin |
5 mg |
$111.40 |
| |
C15H14O5 FW 274.27 [495-85-2] |
10 mg |
$172.10 |
| |
One of the main components in kava kava extract. It has anxiolytic effect and neuroprotective property. |
|
|
| |
Smith KK, Dharmaratne HR, Feltenstein MW. Psychopharmacologia. 155:86-90 (2001). |
|
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| |
Backhauss C, Krieglstein J. Eur J Pharmacol. 215:265-9 (1992). |
|
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| |
|
|
|
| M1879 |
Metoprolol Tartrate |
5 g |
$34.50 |
| |
(C15H25NO3)2.C4H6O6 FW 684.82 [56392-17-7] |
25 g |
$146.30 |
| |
b1-Adrenergic blocker. |
|
|
| |
Prakash A, Markham A. Drugs. 60:647-678 (2000). |
|
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| |
|
|
|
| M1977 |
Metronidazole |
5 g |
$26.00 |
| |
C6H9N3O3 FW 171.15 [443-48-1] |
25 g |
$82.50 |
| |
A nitroimidazole antibiotic that has activity against protozoans and most |
100 g |
$215.30 |
| |
Gram-negative and Gram-positive anaerobic bacteria. It is a potential radiosensitizer |
|
|
| |
for cancer treatment. |
|
|
| |
Freeman CD, Klutman NE, Lamp KC. Drugs. 54:679-708 (1997). |
|
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| |
Acharya DK. Indian J Med Sci. 48:111-6 (1994). |
|
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| |
|
|
|
| M1685 |
Mevastatin |
10 mg |
$93.50 |
|
C23H34O5 FW 390.51 m.p. 1520C [73573-88-3] |
50 mg |
$223.40 |
| |
Antitumor agent. Inhibits isoprenoid biosynthesis and reduces |
|
|
| |
plasma cholesterol levels by the inhibition of HMG-CoA reductase. |
|
|
| |
It arrests cells in the G1 phase. |
|
|
| |
Quesney-Huneeus V, Galick HA, Siperstein MD. J Biol Chem. 258:378-385 (1983). |
|
|
| |
Endo A, J. Lipid Res. 33:1569-1582 (1992). |
|
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| |
|
|
|
| M1687 |
Mevinolin (For sodium salt-please inquire) |
50 mg |
$80.60 |
| |
Lovastatin |
100 mg |
$139.70 |
| |
C24H36O5 FW 404.54 [75330-75-5] |
500 mg |
$501.30 |
| |
Inhibitor of cholesterol biosynthesis rate controlling enzyme, HMG-CoA reductase. |
|
|
| |
Alberts AW, Chen J, Kuron G et al. Proc Natl Acad Sci. USA. 77:3957-3961 (1980). |
|
|
| |
Tobert JA, Bell GD, Birtwell J. et al. J Clin Investigation. 69:913-919 (1982). |
|
|
| |
|
|
|
| M1746 |
Melphalan |
100 mg |
$80.00 |
| |
C13H18Cl2N2O2 FW 305.20 [148-82-3] |
250 mg |
$150.00 |
| |
Is a chemotherapy drug used to treat multiple myeloma and ovarian cancer. |
1 g |
$400.00 |
| |
Phenylamine derivative of mechorethamine. |
|
|
| |
Palumbo, A. Blood (2008), 112(8), 3107-3114. |
|
|
| |
|
|
|
| M2460 |
MGP-pNA |
1 mg |
$53.80 |
| |
C18H25N5O5S FW 423.4 |
10 mg |
$179.20 |
| |
|
|
|
| M3309 |
Miconazole |
1 g |
$26.70 |
| |
C18H14Cl4N2O FW 416.13 [22916-47-8] |
5 g |
$92.60 |
| |
An antifungal agent with good aromatase inhibitory activity, found |
25 g |
$297.70 |
| |
to be an effective chemopreventive agent in a rat mammary cancer model. |
|
|
| |
Lubert RA, Steele VE, Etyo I et al. Int. J. Cancer 72:95-101 (1997). |
|
|
| |
|
|
|
| M3310 |
Miconazole Nitrate |
1 g |
$26.00 |
| |
C18H14Cl4N2O.HNO3 FW 479.15 [22832-87-7] |
5 g |
$86.10 |
| |
An antifungal agent, was found to inhibit platelet cyclooxygenase. |
25 g |
$275.40 |
| |
Ishikawa S, Manabe S, Wada O. Biochem Pharmacol. 35:1787-92 (1986). |
|
|
| |
Sweeny WT. Vet Med Small Anim Clin. 70:1438-40 (1975). |
|
|
| |
|
|
|
| M3219 |
MIF-1 Tyr |
5 mg |
$143.40 |
| |
C22H33N5O5 FW 447.54 |
10 mg |
$243.70 |
| |
A brain peptide that functions as an opiate antagonist in the reduction of contraction. |
25 mg |
$430.10 |
| |
Zedina JE, Kastin AJ, Kersh D, Wyatt A. Life Sci. 51: 869-85 (1991). |
|
|
| |
|
|
|
| M3220 |
Tyr-W-MIF-1 |
5 mg |
$143.40 |
| |
C27H32N6O5 FW 520.59 |
10 mg |
$243.70 |
| |
|
25 mg |
$430.10 |
| |
|
|
|
| M3321 |
Mifepristone |
100 mg |
$51.60 |
| |
RU486 |
500 mg |
$172.10 |
| |
C29H35NO2 FW 429.59 [84371-65-3] |
1 g |
$301.40 |
| |
A glucocorticoid receptor antagonist. It is an effective late post-coital contraceptive |
|
|
| |
and inhibitor of chemical carcinogenesis. |
|
|
| |
Ashok PW, Wagaarachchi PT, Flett GM, Templeton A. Hum Reprod. 16:72-75 (2001). |
|
|
| |
Rocereto TF, Saul HM, Aikins JA Jr. Paulson J. Gynecol Oncol. 77:429-32 (2000). |
|
|
| |
Kanradt MC, Mohideen N, Vaughan AT. ibid. 77:177-82 (2000). |
|
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| |
|
|
|
| M3344 |
Milrinone |
10 mg |
$53.20 |
| |
C12H9N3O FW 211.22 [78415-72-2] |
50 mg |
$220.20 |
| |
A selective phosphodiesterase 3 inhibitor known to effect left ventricular |
100 mg |
$379.50 |
| |
relaxation by inhibiting the breakdown of cAMP in association with an acceleration |
|
|
| |
of sarcoplasmic reticulum Ca(2+)-ATP activity and Ca(2+) uptake. It inhibits |
|
|
| |
platelet aggregation and induces disaggregation. |
|
|
| |
Alousi AA, Canter JM, Montenaro MJ et al. J Cardiovasc Pharmacol. 5:792-803 (1983). |
|
|
| |
Yano M, Kohno M, Ohkusa T et al. Am J Physiol-Heart Circ Physiol 279:H1898-H1905 (2000). |
|
|
| |
Kikura M, Kazama T, Ikeda T, Sato S. Platelets 11:446-458 (2000). |
|
|
| |
|
|
|
| M3353 |
Minocycline Hydrochloride |
100 mg |
$57.50 |
| |
C23H27N3O7.HCl FW 493.94 [13614-98-7] |
250 mg |
$111.40 |
| |
A tetracycline derivative with antimicrobial activity. It was found to inhibit |
500 mg |
$188.60 |
| |
inducible NO synthase expression and augment cyclooxygenase (COX)-2 expression |
|
|
| |
and PGE2 production. Used to treat rheumatoid arthritis. It inhibits angiogenesis. |
|
|
| |
Patel RN, Attur MG, Dave MN et al. J Immunol. 163:3459-67 (1999). |
|
|
| |
Jackson CG, Williams HJ. Drugs. 56:337-44 (1998). |
|
|
| |
Gilbertson-Beadling S, Powers EA, Stamp-Cole M et al. Cancer Chemother Pharmacol. 36:418-24 (1995). |
|
|
| |
|
|
|
| M3453 |
Minoxidil |
100 mg |
$43.10 |
| |
C9H15N5O FW 209.25 [38304-91-5] |
500 mg |
$172.10 |
| |
A vasodilator that has alpha 2-adrenoceptor agonist activity in addition to |
1 g |
$258.20 |
| |
potassium-channel-opening activity. It was found also to have alopecia preventive property. |
|
|
| |
Meisheri KD, Cipkus LA, Taylor CJ. J Pharmacol Exp Ther. 245:751-60 (1988). |
|
|
| |
Sharma N, Mehta AA, Santani DD, Goyal RK. J Pharm Pharmacol. 49:935-7 (1997). |
|
|
| |
Hussein AM. Int J Dermatol. 34:470-3 (1995). |
|
|
| |
|
|
|
| M3368 |
Mirtazapine |
10 mg |
$50.00 |
| |
C17H19N3 FW 365.35 [61337-67-5] |
50 mg |
$200.00 |
| |
is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. |
250 mg |
$650.00 |
| |
Pendeville, P. E., European Journal of Anaesthesiology (2007), 24(6), 546-550. |
|
|
| |
|
|
|
| M3476 |
Mithramycin |
1 mg |
$33.60 |
| |
C52H76O25 FW 1084.47 [18378-89-7] |
5 mg |
$134.40 |
| |
A drug used in chemotherapy that inhibits RNA and protein synthesis. |
10 mg |
$246.40 |
| |
Ray R, Snyder R C, Thomas S, Koller C A, Miller D M J Clin Invest. 83: 2003Ð2007 (1989). |
|
|
| |
|
|
|
| M3577 |
Mitiglinide Calcium |
100 mg |
$75.00 |
| |
C19H24NO3- FW 314.40 [145375-43-5] |
250 mg |
$138.00 |
| |
Mitiglinide is thought to stimulate insulin secretion by closing the |
1 g |
$440.00 |
| |
ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. |
|
|
| |
Sorbera, L. A., Drugs of the Future (2000), 25(10), 1034-1042. |
|
|
| |
|
|
|
| M3377 |
Mitomycin C |
1 mg |
$22.40 |
| |
C15H18N4O5 FW 334.3 [50-07-7] |
5 mg |
$47.00 |
| |
Antineoplastic agent. It inhibits DNA synthesis and induces apoptosis. |
10 mg |
$80.60 |
| |
Tomasz M et al. Science. 235:1204 (1995) |
|
|
| |
Merlo GR et al. J. Cell Biol. 128:1185 (1995). |
|
|
| |
|
|
|
| M3378 |
MitoPTTM |
25 Tests |
$212.00 |
| |
Mitochondrial Membrane Permeability Transition Detection Kit |
100 Tests |
$299.80 |
| |
|
|
|
| M3576 |
Mitotane |
100 mg |
$33.60 |
| |
C14H10Cl4 FW 320.04 [53-19-0] |
500 mg |
$84.00 |
| |
An adrenal cyto-toxic agent used to treat adrenocartical tumors. |
1 g |
$134.40 |
| |
Luton JP, Cerdas S, Billaud L et. al. New England Journal of Medicine 322:1195-1201 (1999). |
|
|
| |
|
|
|
| M3379 |
Mitoxantrone Dihydrochloride |
50 mg |
$89.60 |
| |
C22H28N4O6.2HCl FW 517.41 [70476-82-3] |
100 mg |
$152.20 |
| |
A cytostatic anthraquinone derivative. An antitumor agent that interacts with |
500 mg |
$581.80 |
| |
DNA by intercallation. |
|
|
| |
Faulds D, Balfour JA, Chrisp P, Langtry HD. Drugs 41:400 (1991). |
|
|
| |
|
|
|
| M3584 |
Mivacurium |
25 mg |
$53.80 |
| |
C56H76N2O122+ FW 969.21 [133814-19-4] |
100 mg |
$168.00 |
| |
A bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant |
500 mg |
$700.00 |
| |
Kanyamibwa,D. Methods and Findings in Experimental and Clinical Pharmacology(2008),30(3),187-191. |
|
|
| |
|
|
|
| M3598 |
Mizoribine Hydrobromide |
10 mg |
$112.00 |
| |
C9H14BrN3O6 FW 340.13 [50924-49-7] |
25 mg |
$224.00 |
| |
Is an immunosuppressant drug. First isolated from the mold Eupenicillium |
100 mg |
$728.00 |
| |
brefeldimium antibiotic and cytotoxic effects |
|
|
| |
Nakajo, A. Journal of the American Society of Nephrology (2007), 18(9), 2554-2564. |
|
|
| |
|
|
|
| M5727 |
Moguisteine |
100 mg |
$35.00 |
| |
C16H21NO5S FW 339.41 [119637-67-1] |
250 mg |
$75.00 |
| |
An anti-tussive with similar properties to codeine. |
1 g |
$240.00 |
| |
Morita, K. European Journal of Pharmacology (2000), 395(2), 161-164. |
|
|
| |
|
|
|
| M5746 |
Molsidomine |
500 mg |
$43.10 |
| |
C9H14N4O4 FW 242.23 [25717-80-0] |
1 g |
$72.40 |
| |
An orally active vasodilator that requires hepatic metabolism for activity. |
|
|
| |
Molla A et al. J. Virol. 67:4688 (1993). |
|
|
| |
|
|
|
| M5752 |
Monastrol |
1 mg |
$114.20 |
| |
C14H16N2O3S FW 292.35 [254753-54-3] |
5 mg |
$333.80 |
| |
A cell-permeable small molecule inhibitor of the mitotic kinesin Eg5. It arrests |
|
|
| |
cells in mitosis with monoastral spindles. |
|
|
| |
Kapoor TM, Mayer TU, Coughlin ML et al. J Cell Biol. 150:975-88 (2000). |
|
|
| |
Leizerman I, Avunie-Masala R, Elkabets M et al. Cell Mol Life Sci. 61:2060-70 (2004). |
|
|
| |
|
|
|
| M5753 |
Monensin Sodium Salt |
500 mg |
$34.50 |
| |
C36H62O11 FW 692.86 [22373-78-0] |
1 g |
$60.40 |
| |
A Na+/H+ exchanger found to induce apoptosis in HL-60 cells. |
5 g |
$215.30 |
| |
Zhu WH, Loh TT. Biochem Biophys Acta. 1269:122-8 (1995). |
|
|
| |
|
|
|
| M5853 |
Moniliformin |
1 mg |
$162.40 |
| |
C4H2O3 FW 98.06 [31876-38-7] |
|
|
| |
Is a mycotoxin formed in many cereals. |
|
|
| |
Vestoi, M. Critical Reviews in Food Science and Nutrition (2008), 48(1), 21-49. |
|
|
| |
|
|
|
| M5756 |
Montelukast Sodium |
10 mg |
$43.90 |
| |
C35H36ClNO3S.Na FW 608.17 [151767-02-1] |
25 mg |
$75.30 |
| |
A cysteinyl leukotriene receptor antagonist with anti-inflammatory effects. |
100 mg |
$232.10 |
| |
In rat colitis it has been shown to increase prostaglandin E(2) production and decrease |
|
|
| |
the cyclogenase-2 protein expression. |
|
|
| |
Holma R, Salmenpera P, Riutta A et al. Eur J Pharmacol. 429:309-18 (2001). |
|
|
| |
Schmitt-Grohe S, Eickmeier O, Schubert R et al. Ann Allergy Asthma Immunol. 89:599-605 (2002). |
|
|
| |
|
|
|
| M5675 |
Motilin, canine |
0.5 mg |
$121.90 |
| |
C120H194N36O34 FW 3685.1 |
1 mg |
$207.90 |
| |
|
2.5 mg |
$365.60 |
| |
|
|
|
| M5776 |
Motilin, porcine |
0.5 mg |
$136.20 |
| |
C120H188N34O35S FW 2699.1 [52906-92-0] |
1 mg |
$231.20 |
| |
A peptide that plays a major role in the stimulation of smooth muscles in the |
2.5 mg |
$408.60 |
| |
gastrointestinal tract. |
|
|
| |
Kitazawa T, Taneike T, Ohga A. Peptides. 16:1243-1252 (1995). |
|
|
| |
|
|
|
| M5794 |
Moxifloxacin Hydrochloride |
100 mg |
$92.80 |
| |
C21H24FN3O4.HCl FW 437.89 [186826-86-8] |
500 mg |
$353.00 |
| |
An 8-methoxy-fluoroquinolone antibacterial agent. |
1 g |
$581.80 |
| |
Nightingale CH. Pharmacotherapy. 20:245-56 (2000). |
|
|
| |
|
|
|
| M9608 |
Myclobutanil |
5 g |
$30.50 |
| |
C15H17ClN4 FW 288.78 [88671-89-0] |
10 g |
$53.20 |
| |
A fungicide that inhibits ergosterol biosynthesis. |
50 g |
$189.80 |
| |
Quinn JA et al. Pestic. Sci. 17:357 (1986). |
|
|
| |
|
|
|
| M9710 |
Mycophenolic acid |
50 mg |
$39.20 |
| |
C17H20O6 FW 320.34 [24280-93-1] |
250 mg |
$140.00 |
| |
An immunosuppressive drug used to prevent organ rejection. |
|
|
| |
Ginzler EM, Dooley MA, Aranow C, Kim MY, et al. New England Journal of Medicine. 353: 2219-2229 (2005). |
|
|
| |
|
|
|
| M9643 |
Myelin Basic Protein (1-11), human |
1 mg |
$17.90 |
| |
C52H88N22O17 FW 1293.42 |
2 mg |
$121.90 |
| |
|
5 mg |
$215.00 |
| |
|
|
|
| M9644 |
Myelin Basic Protein (87-99), guinea pig, human |
1 mg |
$71.70 |
| |
C74H114N20O17 FW 1555.8 |
2 mg |
$121.90 |
| |
|
5 mg |
$215.00 |
| |
|
|
|
| M9646 |
Myelin Basic Protein (68-82), guinea pig |
1 mg |
$71.70 |
| |
C71H113N23O28 FW 1736.8 |
2 mg |
$121.90 |
| |
|
5 mg |
$215.00 |
| |
|
|
|
| M9645 |
Myelin Oligodendrocyte Glycoprotein (35-55), rat |
1 mg |
$136.20 |
| |
MOG (35-55) |
2 mg |
$231.20 |
| |
C118H177N35O29S FW 2582.0 |
5 mg |
$408.60 |
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| M9356 |
Myomodulin |
1 mg |
$35.80 |
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C36H67N11O8S2 FW 846.13 |
2 mg |
$60.90 |
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A neuropeptide that inhibits the electrophysiological effects of sensory neurons. |
5 mg |
$107.50 |
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Critz SD, Baxter D. A. Byrne J.H. Journal of Neurophysiology 66: 1912-1926 (1991). |
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| M9367 |
Myricetin |
10 mg |
$29.80 |
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C15H10O8 FW 318.2 [529-44-2] |
25 mg |
$49.60 |
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A common flavonol in plants, which inhibits the human P-form phenolsulfotransferase. |
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Eaton EA, Walle UK, Lewis AJ et al. Drug Metab Disp. 24:232-237 (1997). |
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| M9634 |
Myriocin |
1 mg |
$20.20 |
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C21H39NO6 FW 401.54 [35891-70-4] |
5 mg |
$67.20 |
| |
Also known as antibiotic ISP-1, thermozymodcidin is an atypical amino acid |
10 mg |
$112.00 |
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derived from fungi. A very potent inhibitor of serine palmtoyl transferase. Possesses |
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immunosuppressant activity and is 10X more potent than cyclosporine. |
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Ciesek, S. Journal of Infectious Diseases (2008), 198(7), 1091-1093 |
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| M9368 |
Myristicin |
100 mg |
$82.90 |
| |
C11H12O3 FW 192.21 d 1.1437 [607-91-0] |
500 mg |
$276.00 |
| |
Natural product isolated from parsley oil. Inducer of glutathione S-transferase |
1 g |
$482.90 |
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enzymes and inhibitor of chemical carcinogenesis. |
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Zheng G-q, Kenney PM, Lam LKT. J. Agri. Food Chem. 40:107-110 (1992). |
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Zheng G-q, Kenney PM. Zhang J, Lam LKT. Carcinogenesis. 13:1921-23 (1992). |
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