| N0205 |
Nabumetone |
5 g |
$51.60 |
| |
C15H16O2 FW 228.29 [42924-53-8] |
25 g |
$168.70 |
| |
A non-steroidal anti-inflammatory drug. Works by inhibiting cyclooxygenase, |
|
|
| |
an enzyme responsible for making prostaglandins which are mediators of inflammation. |
|
|
| |
It also has chemopreventive effect on chemically induced mammary carcinogenesis in rats. |
|
|
| |
Matsunga K, Yoshimi N, Yamada Y et al. Jpn J Cancer Res. 89:496-501 (1998). |
|
|
| |
|
|
|
| N0114 |
Nadifloxacin |
25 mg |
$53.20 |
| |
C19H21FN2O4 FW 360.38 [124-858-35-1] |
100 mg |
$144.30 |
| |
A fluoroquinolone antibacterial agent. It was found to inhibit the generation of |
500 mg |
$569.30 |
| |
O2- and OH radicals by neutrophils. |
|
|
| |
Ishikawa H, Tabusa F, Miyamoto H et al. Chem Pharm Bull 37:2103-2108 (1989). |
|
|
| |
Akamatsu H, Sasaki H, Kurokawa I et al. J Int. Med Res. 23:19-26 (1995). |
|
|
| |
|
|
|
| N0123 |
Naftopidil |
25 mg |
$50.40 |
| |
[57149-07-2] |
100 mg |
$162.40 |
| |
An anti-hypertension drug. |
500 mg |
$504.00 |
| |
Kanda, H. International Journal of Cancer (2007), Volume Date 2008, 122(2), 444-451. |
|
|
| |
|
|
|
| N0262 |
Naphazoline Hydrochloride |
25 g |
$41.40 |
| |
C14H14N2.HCl FW 246.74 [835-31-4] |
100 g |
$144.90 |
| |
Naphazoline produces inotropic effects via a-adrenoceptor stimulation. |
|
|
| |
Endoh M, Schumann HJ. Naunyn Schmiedebergs Arch Pharmacol. 287:377-89 (1975). |
|
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| |
|
|
|
| N0263 |
Naphazoline Nitrate |
10 g |
$34.50 |
| |
C14H14N2.HNO3 FW 273.29 [5144-52-5] |
25 g |
$75.90 |
| |
|
100 g |
$262.20 |
| |
|
|
|
| N0161 |
b-Naphthoflavone |
1 g |
$43.10 |
| |
5, 6 -Benzoflavone |
5 g |
$150.00 |
| |
C19H12O2 FW 272.3 [6051-87-2] |
|
|
| |
An inducer of cytochrome P450 enzyme system. Protects chemical-induced carcinogenesis |
|
|
| |
by enhancing the detoxification of carcinogens. |
|
|
| |
Callander RD, Mackay JM, Clay P. Mutagenesis. 10:517-22 (1995). |
|
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| |
Anderson LM, Seetharam S. Cancer Res. 45:6384-9 (1985). |
|
|
| |
|
|
|
| N0160 |
NAP |
0.5 mg |
$22.40 |
| |
C36H60N10O12 FW 824.94 |
1 mg |
$38.10 |
| |
|
2.5 mg |
$67.20 |
| |
|
|
|
| N0163 |
2-(1,8-Naphthyridin-2-ly)phenol |
500 mg |
$88.70 |
| |
2-NP |
1 g |
$147.80 |
| |
C14H10N2O FW 222.24 [65182-56-1] |
5 g |
$616.00 |
| |
It was shown to enhance IFN-g ability to inhibit the proliferation of human breast. |
|
|
| |
cancer and fibrosarcoma cells. |
|
|
| |
Lynch RA, Etchin J, Battle TE, Frank DA Cancer Res. 67: 1254-1261 (2007). |
|
|
| |
|
|
|
| N0061 |
D-Naproxen |
5 g |
$39.40 |
| |
C14H14O3 FW 230.26 m.p. 155-1580C [22204-53-1] [a]66.80 |
25 g |
$137.60 |
| |
A non-steroidal anti-inflammatory agent found to significantly inhibit NNK |
50 g |
$251.40 |
| |
activation in lung tissues. |
|
|
| |
Bouchard L, Castonguay A. Drug Metab. Disp. 21: 293-298 (1993). |
|
|
| |
|
|
|
| N0062 |
D,L-Naproxen |
10 g |
$40.40 |
| |
C14H14O3 FW 230.26 m.p. 152-1540C [22204-53-1] |
25 g |
$90.60 |
| |
A non-steroidal anti-inflammatory agent found to significantly |
100 g |
$286.70 |
| |
inhibit NNK activation in lung tissues. |
|
|
| |
Bouchard L, Castonguay A. Drug Metab. Disp. 21: 293-298 (1993). |
|
|
| |
|
|
|
| N0068 |
Naringenin |
5 g |
$54.80 |
| |
|
10 g |
$72.90 |
| |
The aglycone of naringin, a dietary flavonoid found in grapefruit |
25 g |
$159.50 |
| |
juice. An effective anti-oxidant and antimutagen. |
|
|
| |
Guengerich FP, Kim DH. Carcinogenesis. 11:2275-2279 (1990). |
|
|
| |
Calomme M, Pieters L, Vlietinck A, Berghe D. Planta Med. 62:222-226 (1996). |
|
|
| |
|
|
|
| N0069 |
Naringin |
25 g |
$30.50 |
| |
C27H32O14 FW 580.53 [10236-47-2] |
100 g |
$91.20 |
| |
A citrus bioflavonoid found to inhibit cytochrome P450 monooxygenase activity |
|
|
| |
in mouse liver. It prevents toxin-induced cytoskeletal disruption and apoptotic liver |
|
|
| |
cell death. In addition, it was found to have hypocholesterolemic effect by inhibiting |
|
|
| |
HMG-CoA reductase and ACAT activities. |
|
|
| |
Ueng YF, Chang YL, Oda Y et al. Life Sci. 65:2591-2602 (1999). |
|
|
| |
Blankson H, Grotterod EM, Seglen PO. Cell Death Diff. 7:739-746 (2000). |
|
|
| |
Shin YW, Nok SH, Jeong TS et al. Int. J. Vit. Nutr. Res. 69:341-347 (1999). |
|
|
| |
|
|
|
| N0075 |
Natamycin |
25 mg |
$112.90 |
| |
Pimaricin |
50 mg |
$188.20 |
| |
C33H47NO13 FW 665.73 [7681-93-8] |
100 mg |
$345.00 |
| |
A polyene antifungal compound, shown to potentiate bleomycin activity against murine tumors. |
|
|
| |
Komiyama K, Umezawa I, Kuwano M et al. Gann. 74:602-6 (1983). |
|
|
| |
Brothers AM, Wyatt RD. Avian Dis. 44:490-7 (2000). |
|
|
| |
|
|
|
| N0212 |
Nedaplatin |
10 mg |
$129.20 |
| |
C2H8N2O3Pt FW 303.18 [95734-82-0] |
25 mg |
$289.30 |
| |
A platinum complex that has potent antineoplatic activity. |
50 mg |
$516.30 |
| |
Yamada H, Uchida N, Maekawa R, Yoshioka T. Cancer Lett. 172:17-25 (2001). |
|
|
| |
Uchida N, Takeda Y, Kasai H. Anticancer Res. 18:3375-9 (1998). |
|
|
| |
|
|
|
| N1822 |
Nefazodone Hydrochloride |
1 g |
$38.60 |
| |
C25H32ClN5O2.HCl FW 506.48 [82752-99-6] |
5 g |
$165.60 |
| |
An antidepressant acts by modifying serotonin transmission. It also exhibits |
25 g |
$579.60 |
| |
analgesic effect in mice. |
|
|
| |
Eison AS, Eison MS, Torrente JR et al. Psychopharmacol Bull. 26:311-5 (1990). |
|
|
| |
Pick CG, Paul D, Eison MS. Pasternak GW. Eur J Pharmacol. 211:375-81 (1992). |
|
|
| |
Owens MJ, Ieni JR, Knight DL et al. Life Sci. 57:PL373-80 (1995). |
|
|
| |
|
|
|
| N1721 |
Nefiracetam |
100 mg |
$50.40 |
| |
C14H18N2O2 FW 246.3 [77191-36-7] |
250 mg |
$100.80 |
| |
Is a nootropic drug of the racetam family used in the treatment of AlzheimerÕs |
1 g |
$308.00 |
| |
disease and other diseases related to learning and memory deficits. |
|
|
| |
Moriguchi, S. Molecular Pharmacology (2007), 71(2), 580-587. |
|
|
| |
Moriguchi, S. Journal of Neurochemistry (2008), 106(3), 1092-1103 |
|
|
| |
|
|
|
| N1755 |
Neomycin sulfate |
1 g |
$11.40 |
| |
C23H46N6O13.3H2SO4 FW 908.9 [1405-10-3] |
5 g |
$14.90 |
| |
Antibacterial produced by Streptomyces fradiae. |
10 g |
$17.10 |
| |
Taborsky I, Nezval J, Smekal E, Janisch R. J Hyg Epidemiol Microbiol Immunol. |
25 g |
$34.50 |
| |
11:359-67 (1967). |
|
|
| |
Macdonald RH, Beck M. Clin Exp Dermatol. 8:249-58 (1983). |
|
|
| |
|
|
|
| N1656 |
Neopterin |
10 mg |
$38.30 |
| |
C9H11N5O4 FW 253.21 [670-65-5] |
|
|
| |
A prognostic marker for the progression of immunodefeciency. |
|
|
| |
Prommegger R, Winder B, Murr C et al. Ann Thorac Surg. 70:1861-4 (2000). |
|
|
| |
|
|
|
| N1757 |
Neostigmine Bromide |
250 mg |
$19.80 |
| |
Prostigmine |
1 g |
$29.80 |
| |
C12H19BrN2O2 FW 303.20 [114-80-7] |
|
|
| |
An acetylcholine esterase inhibitor. It has protective effects against gastric carcinogenesis. |
|
|
| |
It also may provide analgesia in patients with pain arising from neoplasia. |
|
|
| |
Tatsuta M, Iishi H, Baba M, Taniguchi H. Int J Cancer. 51:767-71 (1992). |
|
|
| |
Klamt JG, Dos Reis MP, Barbier neto J, Prado WA. Pain. 66:389-91 (1996). |
|
|
| |
|
|
|
| N1769 |
Nerolidol |
5 g |
$20.70 |
| |
C15H26O FW 222.37 [7212-44-4] |
25 g |
$44.90 |
| |
It has inhibitory effects on carcinogenesis of the large bowel. |
|
|
| |
Warttenberg LW. Carcinogenesis. 12:151-2 (1991). |
|
|
| |
|
|
|
| N1873 |
Nesiritide Acetate (BNP-32) |
Please inquire |
|
| |
C143H244N50O42S4 FW 3464.1 [11447-18-0] |
|
|
| |
Nesiritide is a sterile, purified preparation of a new drug class, human B-type natriuretic |
|
|
| |
peptide (hBNP), and is manufactured from E. coli using recombinant DNA technology. |
|
|
| |
Sun Z, Chen J, Yao H, Liu L, Wang J, Zhang J, Liu JN. Protein Expr Purif. 43:26-32 (2005). |
|
|
| |
|
|
|
| N1976 |
Netilmicin Sulfate |
5 mg |
$138.00 |
| |
1-N-Ethylsisomicin |
10 mg |
$207.00 |
| |
(C21H41N5O7)2.5H2SO4 FW 1441.56 [56391-57-2] |
25 mg |
$414.00 |
| |
A aminoglycoside antibiotic. It is a semisynthetic derivative of gentamycin. |
|
|
| |
Scuderi AC, Paladino GM, Marino C et al. Cornea. 22:468-72 (2003). |
|
|
| |
Adelman RD, Conzelman G, Spangler W et al. Curr Probl Clin Biochem. 9:166-82 (1979). |
|
|
| |
|
|
|
| N1977 |
Neurokinin A (4-10) |
1 mg |
$50.20 |
| |
C34H54N8O10S FW 766.92 |
2 mg |
$85.30 |
| |
A selective NK1 receptor agonist against tachykinin receptors. |
5 mg |
$150.50 |
| |
Teixeira RM, Santos AR, Ribeiro SJ, Calixto JB, Rae GA, DeLima TC. Eur J Pharmacology 311: 7-14 (1996). |
|
|
| |
|
|
|
| N1978 |
Neurokinin B |
1 mg |
$43.00 |
| |
C55H79N13O14S2 FW 1210.45 |
2 mg |
$73.10 |
| |
A peptide thought to be responsible for pre-eclampsia in women. |
5 mg |
$129.00 |
| |
Page NM, Woods RJ, Gardiner SM, Lomthaisong K, Gladwell RT, Butlin DJ, |
|
|
| |
Manyonda IT, Lowry PJ. Nature 405: 797-800 (2000). |
|
|
| |
|
|
|
| N1979 |
Neuromedin |
1 mg |
$28.70 |
| |
C38H63N7O8 FW 745.97 |
2 mg |
$48.80 |
| |
|
5 mg |
$86.00 |
| |
|
|
|
| N1980 |
Neuromedin B, porcine |
1 mg |
$57.30 |
| |
C52H73N15O12S FW 1132.3 [87096-84-2] |
2 mg |
$97.60 |
| |
Neuromedin B and C are bombesin-like peptides. They have various |
5 mg |
$172.00 |
| |
physiological effects, including regulation of exocrine and endocrine secretions, |
|
|
| |
smooth muscle contraction, feeding, blood pressure, blood glucose, body temperature and cell growth. |
|
|
| |
Ohki-Hamazaki H. Prog Neurobiol. 62:297-312 (2000). |
|
|
| |
|
|
|
| N1981 |
Neuromedin C, porcine GRP (18-27) |
1 mg |
$89.60 |
| |
C50H73N17O11S FW 1120.3 [81608-30-2] |
|
|
| |
|
|
|
| N1982 |
Neuromedin U, rat |
1 mg |
$121.90 |
| |
C124H180N34O31 FW 2643.03 |
2 mg |
$207.20 |
| |
A neuropeptide which affects smooth muscle. It was first isolated from porcine spinal cord |
5 mg |
$365.60 |
| |
Howard AD Et Al. Nature 406: 70-4 (2000). |
|
|
| |
|
|
|
| N1984 |
Neuropeptide FF F-8-F-NH2 |
5 mg |
$134.40 |
| |
C54H76N14O10 FW 1081.3 [99566-27-5] |
10 mg |
$229.40 |
| |
|
25 mg |
$403.20 |
| |
|
|
|
| N1985 |
Neuropeptide K, porcine |
5 mg |
$573.40 |
| |
C175H284N52O52S FW 5980.6 |
10 mg |
$974.80 |
| |
Isolated from porcine spinal cord. It was shown to exert control over neural |
25 mg |
$1,720.30 |
| |
transmission. |
|
|
| |
Tatemoto K, Lundberg JM, Jornvall H, Mutt V. Biochem Biophys Res Commun 128: 947-53 (1985). |
|
|
| |
|
|
|
| N1983 |
Neuropeptide Y (3-36), human |
0.5 mg |
$121.90 |
| |
C175H269N53O54S FW 4011.48 |
1 mg |
$206.10 |
| |
A neuropeptide thought to be associated with food intake. |
2.5 mg |
$365.60 |
| |
Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE, |
|
|
| |
Low MJ, Ghatei MA, Cone RD, Bloom SR. Nature 418: 650-4 (2002). |
|
|
| |
|
|
|
| N1987 |
Neuropeptide Y (13-36), human |
0.5 mg |
$109.30 |
| |
C134H207N41O36S FW 3000.46 |
1 mg |
$182.80 |
| |
|
2.5 mg |
$322.60 |
| |
|
|
|
| N1986 |
Neuropeptide Y, human, rat |
5 mg |
$573.40 |
| |
C189H285N55O57S FW 4271.7 |
10 mg |
$974.80 |
| |
|
25 mg |
$1,720.30 |
| |
|
|
|
| |
|
|
|
| N1988 |
g-Neuropeptide, rabbit |
0.5 mg |
$107.50 |
| |
C99H158N34O29S FW 2320.64 |
1 mg |
$182.80 |
| |
When injected into the heart of a rabbit, a decrease in blood flow was induced. |
2.5 mg |
$322.60 |
| |
Allen JM, Bircham PM, Edwards AV, Tatemoto K, Bloom SR. Regul Peptide 6: 247-53 (1983). |
|
|
| |
|
|
|
| N1989 |
Neurotensin |
1 mg |
$35.80 |
| |
C78H122N21O20 FW 1672.9 [39379-15-2] |
2 mg |
$60.90 |
| |
A gut regulatory peptide that exerts a wide range of biological actions on |
5 mg |
$107.50 |
| |
gastrointestinal tissues. It has been shown to potentiate the proliferative effects of |
|
|
| |
insulin on IMR90 human fibroblasts. |
|
|
| |
Scarpa RC, Carraway RE, Cochrane DE. Peptides. 25:1159-69 (2004). |
|
|
| |
Assimakopoulos SF, Vagianos CE, Zervoudakis G et al. Regul Pept. 120:185-93 (2004). |
|
|
| |
|
|
|
| N1990 |
[Gln4] Neurotensin |
1 mg |
$35.80 |
| |
C78H122N22O19 FW 1671.9 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| N1991 |
[D-Trp11] Neurotensin |
5 mg |
$107.50 |
| |
C80H122N22O19 FW 1696.0 |
10 mg |
$182.80 |
| |
|
25 mg |
$322.60 |
| |
|
|
|
| N1992 |
Neurotensin (1-11) |
1 mg |
$35.80 |
| |
C66H99N19O18 FW 1446.66 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| N1993 |
Neurotensin (9-13) |
5 mg |
$107.50 |
| |
C32H52N8O7 FW 660.82 |
10 mg |
$182.80 |
| |
|
25 mg |
$322.60 |
| |
|
|
|
| N1994 |
Neurotensin, frog |
0.5 mg |
$21.50 |
| |
C70H115N23O17 FW 1550.84 |
1 mg |
$35.80 |
| |
|
2.5 mg |
$64.50 |
| |
|
|
|
| N1995 |
Neurotensin, guinea pig |
1 mg |
$35.80 |
| |
C76H119N21O21 FW 1662.92 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| N3310 |
Nicotinamide |
50 g |
$51.60 |
| |
C6H6N2O FW 122.12 [98-92-0] |
|
|
| |
A naturally occurring vitamin that is a protease inhibitor. Topical nicotinamide has demonstrated |
|
|
| |
preventive activity against photo carcinogenesis in mice by elevating skin nicotinamide-adenine |
|
|
| |
dinucleotide (NAD) content. It also has protective effects against lung and pancreatic |
|
|
| |
carcinogenesis. |
|
|
| |
Gensler HL, Williams T, Huang AC, Jacobson EL. Nutr Cancer. 34:36-41 (1999). |
|
|
| |
Nikonova TV, Draudin-Krylenko VA, Bukin Iu V, Turusov VS. Eksp Onkol. 10:17-9 (1998). |
|
|
| |
Pour PM, Lawson T. J Natl Cancer Inst. 73:767-70 (1984). |
|
|
| |
|
|
|
| N3213 |
Nidulal |
0.5 mg |
$341.20 |
| |
C15H16O5 FW 276.28 |
|
|
| |
A natural product isolated from Nidula candida. It induces differentaition of human HL-60 |
|
|
| |
promyelocytic leukemia cells, and preferentially activates the transcription factor complex |
|
|
| |
AP-1-mediated expression of secreted alkaline phosphatase in COS-7 cells. |
|
|
| |
Erkel G, Necker U, Anke T et al. J Antibiot (Tokyo) 49:1189-95 (1996). |
|
|
| |
|
|
|
| N3228 |
Nifedipine |
1 g |
$34.50 |
| |
4-(2'nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine |
5 g |
$89.60 |
| |
C17H18N2O6 FW 346.3 [21829-25-4] |
25 g |
$258.20 |
| |
Ca+2 channel blocker, induces apoptosis in human glioblastoma cells. |
|
|
| |
Miller RJ. Science. 235:46 (1987). |
|
|
| |
|
|
|
| N3422 |
Nifekalant Hydrochloride |
10 mg |
$89.70 |
| |
C19H27N5O5.HCl FW 441.91 [130656-51-8] |
25 mg |
$172.50 |
| |
A class III antiarrhythmic drug. It has been shown to be effective against ventricular |
|
|
| |
tachyarrhythmias by inhibiting HERG channels in a voltage-dependent and |
|
|
| |
frequency-dependent manner. |
|
|
| |
Kushida S, Ogura T, Komuro I et al. Eur J Pharmacol. 457:19-27 (2002). |
|
|
| |
Shiga T, Matsuda N, Fuda Y et al. J Cardiol. 39:159-64 (2002). |
|
|
| |
|
|
|
| N3322 |
Niflumic acid |
10 g |
$38.10 |
| |
C13H9F3N2O2 FW 282.22 [4394-00-7] |
25 g |
$68.40 |
| |
A NSAID, found to be a potent anion channel blocker. |
|
|
| |
White MM, Aylwin M. Mol. Pharm. 37:720-724 (1990). |
|
|
| |
|
|
|
| N3520 |
Nifursol |
25 g |
$62.20 |
| |
Salfuride |
100 g |
$172.50 |
| |
C12H7N5O9 FW 365.21 [16915-70-1] |
|
|
| |
An antibiotic used as a feed additive. |
|
|
| |
Callait MP, Granier C, Chauve C et al. Poult Sci. 81:1122-7 (2002). |
|
|
| |
Kowalski P, Oledzka I, Lamparczyk H. J Pharm Biomed Anal. 32:937-47 (2003). |
|
|
| |
|
|
|
| N3225 |
Nigericin |
1 mg |
$22.40 |
| |
C40H67O11Na FW 747.0 [28643-80-3] |
5 mg |
$54.50 |
| |
A potassium ionophore, found to induce cell death and promote the maturation |
10 mg |
$101.90 |
| |
and release of IL-1beta in lipopolysaccharide primed monocytes and macrophages. |
|
|
| |
It also enhances rapamycin action. |
|
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| |
Fang A, Wong GK, Demain AL. J Antibiot (Tokyo). 53:158-62 (2000). |
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Hentze H, Lin XY, Choi MS et al. Cell Death Differ. 10:956-68 (2003). |
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| N3230 |
Nigrin b |
1 mg |
$258.20 |
| |
Nigrin b is a two chain type 2 ribosome-inactivating protein isolated from elder bark |
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(Sambucus nigra L.). It inhibits protein synthesis by inactivation of mammalian ribosomes |
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but not plant nor E. coli ribosomes. |
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Girbes T et al. Plant Mol. Biol. 22, 1181 (1993). |
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Batelli MG et al. Arch. Toxicol. 71, 360 (1997). |
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Olsnes S et al. J.Biol. Chem. 249, 803 (1993). |
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| N3346 |
Nilotinib |
10 mg |
$196.00 |
| |
C28H22F3N7O FW 529.52 [641571-10-0] |
25 mg |
$392.00 |
| |
Tyrosine kinase inhibitor used in the treatment of drug resistant myelogenous |
100 mg |
$1,008.00 |
| |
leukemia with promising results often resulting in full recovery of white blood cell count. |
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Day, E. European Journal of Pharmacology (2008), 599(1-3), 44-53. |
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Tiribelli, M. Leukemia Research (2009), 33(1), 174-177. |
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| N3450 |
Nimesulide |
5 g |
$43.10 |
| |
C13H12N2O5S FW 308.31 [51803-78-2] |
10 g |
$77.60 |
| |
Inhibits prostaglandin synthetase (COX-2 inhibitor), and has anti-inflammatory |
25 g |
$155.00 |
| |
activity. It induces apoptosis and inhibits carcinogenesis. |
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Huskisson EC. Clin Exp Rheumatol. 19:S21-5 (2001). |
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Kitayama W, Denda A, Okajima E. Carcinogenesis. 20:2305-10 (1999). |
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Hida T, Kozaki K, Muramatsu H. Clin Cancer Res. 6:2006-11 (2000). |
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Nakatsugi S, Ohta T, Kawamori T. Jpn J Cancer Res. 91:886-92 (2000). |
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| N3448 |
Nimodipine |
500 mg |
$55.20 |
| |
C21H26N2O7 FW 418.44 [66085-59-4] |
1 g |
$96.70 |
| |
A calcium channel antagonist. |
5 g |
$345.00 |
| |
Gupta MC, Garg SK, Das BP, Bhargava VK. Indian J Physiol Pharmacol. 47:347-51 (2003). |
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| N3452 |
Nimustine Hydrochloride |
100 mg |
$38.10 |
| |
1-(4-amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitrosourea,ACNU |
500 mg |
$83.60 |
| |
C9H13ClN6O2.HCl FW 309.16 [55661-38-6] |
1 g |
$113.90 |
| |
DNA cross-linker used to treat malignant glioma. |
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| |
Kono K, Takahashi JA, Ueba T. J. Neuro-Oncol. 56:101-108 (2002). |
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9-Nitro-20(S)-camptothecin(See Camptothecin, 9-nitro-20(S)) |
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| N3278 |
7-Nitroindazole |
500 mg |
$62.20 |
| |
C7H5N3O2 FW 163.13 [2942-42-9] |
1 g |
$82.90 |
| |
A neuronal nitric oxide synthase (nNOS) inhibitor. It enhances amphetamine- |
5 g |
$276.00 |
| |
evoked release, and kainic acid induced cholinergic neurotoxicity in the rat striatum. |
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| |
Guevara BH, Cespedes GC, Cubeddu LX. Cell Mol Neurobiol. 22:827-34 (2002). |
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Nowak P, Brus R, Oswiecimska J et al. J Physiol Pharmacol. 53:251-63 (2002). |
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| N3276 |
Nitroso(acetoxymethyl)methylamine |
10 mg |
$84.00 |
| |
C4H8N2O3 FW 132.12 [56856-83-8] |
50 mg |
$251.90 |
| |
Stable derivative of dimethylnitrosoamine metabolite, a potent carcinogen. |
100 mg |
$443.50 |
| |
Frank N, Janzowski C, Wiessler M. Biochem. Pharm. 29:383-7 (1980). |
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Rice JSR, Wenk JM, Roller ML, Keefer LK. J. Nalt. Cancer Inst. 58:1531-35 (1977). |
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| N3378 |
S-Nitrosoglutathione |
5 mg |
$56.10 |
| |
C10H16N4O7S FW 336.32 [57564-91-7] |
10 mg |
$94.80 |
| |
An antioxidant that annihilates free radicals and promotes neuro protection |
25 mg |
$127.00 |
| |
via its c-GMP independent nitrosylation actions. It is also reported that |
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| |
S-nitrosoglutathione induces apoptosis in human adenocarcinoma cells in the presence of Cu and Ni ions. |
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| |
Chiueh CC, Rauhala P. Free Radic Res. 31:641-50 (1999) |
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| |
Ho Y S, Liu H L, Duh J S et al. Molecular Carcinogenesis. 26:201-11 (1999). |
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| N3496 |
Nizatidine |
5 g |
$37.60 |
| |
C12H21N5O2S2 FW 331.46 [76963-41-2] |
10 g |
$62.70 |
| |
A H2-receptor antagonist, found to be a potent inhibitor of gastric acid secretion. |
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| |
Lin TM, Evans DC, Warrick MW et al. J Pharmacol Exp Ther. 239:406-10 (1986). |
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| |
Abdel-Rahman SM, Johnson FK, Connor JD et al. J Pediatr Gastroenterol Nutr. 38:442-51 (2004). |
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| N5210 |
Nociceptin |
1 mg |
$180.70 |
| |
Orphanin FQ |
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| |
C79H129N27O22 FW 1809.1 [170713-75-4] |
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The endogenous ligand for the opioid-receptor-like receptor 1. It mediates essential functions in |
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the central and peripheral nervous systems. |
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| |
Li N, Wei SY, Yu LC et al. Brain Res. 1025:67-74 (2004). |
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| N5211 |
Nocistatin |
0.5 mg |
$215.00 |
| |
|
1 mg |
$365.60 |
| |
|
2.5 mg |
$645.10 |
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| N5409 |
Nocodazole |
10 mg |
$106.40 |
| |
|
50 mg |
$392.00 |
| |
Microtubule inhibitor. |
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| |
Karbowski M, Spodnik JH, Teranishi Ma et al. J Cell Sci. 114:281-291 (2001). |
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Samson F, Donoso JA, Heller-Bettinger I et al. J Pharmacol Exp Ther. 208:411-7 (1979). |
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| N5550 |
Nomilin |
25 mg |
$84.10 |
| |
C28H34O9 FW 314.3 m.p. 257-2610C [1063-77-0] |
100 mg |
$209.80 |
| |
Nomilin is a natural product isolated from grapefruit seed. It is an inducer of |
500 mg |
$734.40 |
| |
Phase II detoxifying enzymes and inhibitor of chemcially induced carcinogenesis. |
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| |
Maier V P, Hasegawa S, Bennett, R. D, Echols L.C. In: Citrus Nutrition and |
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| |
Quality, ed. by S. Nagy and J. A. Attaway, ACS Symposium Series 143, ACS, Washington, D.C. pp 63-81 (1980). |
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Lam LKT, Hasegawa S. Nutr. Cancer. 12:43-47 (1989). |
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| |
Miller EG, Fanous R, Rivera-Hidalgo F et al. Carcinogenesis. 10:1535-1537 (1989). |
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| N5652 |
Nonactin |
1 mg |
$22.40 |
| |
C40H64O12 FW 736.934 [6833-84-7] |
5 mg |
$44.80 |
| |
A selective ionophore used in the determination of ammonium ions. |
10 mg |
$80.60 |
| |
Karakus E, Pekyardimci S, Kilic E. Artif Cells Blood Substit Immobil Biotechnol. 34:523-34 (2006). |
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| N5655 |
Nonoxynol, n=9 |
50 g |
$34.50 |
| |
C33H60O10 FW 616.82 [26027-38-3] |
100 g |
$60.40 |
| |
Polyoxynol nonylpheyl ether, a surfactant used as a vaginal contraceptive and condom luricant. |
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| |
Van damme L. AIDS Read. 10:552-4. (2000). |
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| |
Sonnenschein C, Soto AM. J Steroid Biochem Mol Biol. 65:143-50 (1998). |
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Noradrenaline (See Norepinephrine) |
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| N5669 |
Nordihydroguaiaretic acid |
500 mg |
$58.00 |
| |
C18H22O4 FW 302.36 [500-38-9] |
1 g |
$99.50 |
| |
A naturally ocurring antioxidant and potent lipoxygenase inhibitor |
5 g |
$372.60 |
| |
with antipromoter activity. |
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Nakadate T, Yamamoto S, Iseki H et al. Gann. 73:841-843 (1982). |
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| N5766 |
Norepinephrine bitartrate |
500 mg |
$77.60 |
| |
C8H11NO3.C4H6O6 FW 319.26 [69815-49-2] |
1 g |
$120.50 |
| |
Norepinephrine activates protein kinases Erk1/2. It is cytotoxic to human promyelocytic |
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| |
leukemic HL-60 cells. |
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| |
Lindquist JM, Fredriksson JM, Rehnmark S et al. J Biol Chem. 275:22670-7 (2000). |
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Kawase M, Motohashi N, Kurihara T et al. Anticancer Res. 18:1069-74 (1998). |
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| N5767 |
Norethindrone |
250 mg |
$44.20 |
| |
Norethisterone |
1 g |
$71.80 |
| |
C20H26O2 FW 298.42 [68-22-4] |
5 g |
$276.00 |
| |
A synthetic progestin that possesses antiestrogenic effects. It is progestational in low dose and |
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| |
antiestrogenic in high dose. It has also been shown to cause a time-dependent loss of cytochrome |
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| |
P-450 when incubated in vitro with rat liver microsomal fractions and NADPH-generating systems. |
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White IN, Muller-Eberhard U. Biochem J. 166:57-64 (1997). |
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Tamaya T, Ishihara S, Motoyama T et al. Nippon Naibunpi Gakkai Zasshi. 51:1033-42 (1975). |
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Norethisterone (See Norethindrone) |
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| N5768 |
Norfloxacin |
10 g |
$62.90 |
| |
C16H18FN3O3 FW 319.33 m.p. 227-2280C [70458-96-7] |
50 g |
$223.70 |
| |
A fluorosquinolone antibacterial. |
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| N5769 |
Norfloxacin Nicotinate |
10 g |
$62.20 |
| |
C16H18FN3O3C6H5NO2 FW 442.44 [118803-81-9] |
50 g |
$220.90 |
| |
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| |
Norgestrel (See Levonorgestrel) |
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| N5778 |
Notoginsenoside R1 |
5 mg |
$106.30 |
| |
C47H80O17 FW 917.13 [80418-24-2] |
10 mg |
$182.20 |
| |
Active ingredient isolated from Panax notoginseng. It induces tissue-type |
25 mg |
$356.80 |
| |
plasminogen activator synthesis in cultured human umbilical vein endothelial cells |
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| |
Zhang W, Wojta J, Binder BR. Arterio Throm. 14:1040-1046 (1994). |
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| N6020 |
NPF |
1 mg |
$114.70 |
| |
C51H80N15O19P FW 768.79 |
2 mg |
$193.50 |
| |
|
5 mg |
$344.10 |
| |
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| N6076 |
N(p-Tosyl)-GPR-pNA |
100 mg |
$600.30 |
| |
C26H34N8O7S FW 602.0 |
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| N7604 |
NTB (Naltriben) |
0.5 mg |
$78.80 |
| |
C50H65N11O11S2 FW 1060.29 |
1 mg |
$132.60 |
| |
An opoid antagonist that has been shown to suppress alcohol intake in rats. |
2.5 mg |
$236.50 |
| |
Krishnan-Sarin S, Portoghese PS, Li TK, Frohlich JC. Pharmcol Biochem Behav 52: 153-9 (1995). |
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| N9874 |
Nystatin |
500 KU |
$14.00 |
| |
C47H75NO17 FW 926.09 [1400-61-9] |
1 MU |
$16.50 |
| |
An antifungal drug. |
5 MU |
$41.10 |
| |
Patton LL, Bonito AJ, Shugars DA. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 92:170-9 (2001). |
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