Sulforaphane
See LKT's Specialty Chemicals
See LKT's Product Line
 
Alphabetized - N
N0205 Nabumetone
A non-steroidal anti-inflammatory drug. Works by inhibiting cyclooxygenase, an enzyme responsible for making prostaglandins which are mediators of inflammation. It also has chemopreventive effect on chemically induced mammary carcinogenesis in rats.

Matsunga K, Yoshimi N, Yamada Y et al. Jpn J Cancer Res. 89:496-501 (1998).
5 g
25 g
$46.10
$150.60
N0114 Nadifloxacin
A fluoroquinolone antibacterial agent. It was found to inhibit the generation of O2- and OH radicals by neutrophils.

Ishikawa H, Tabusa F, Miyamoto H et al. Chem Pharm Bull 37:2103-2108 (1989).
25 mg
100 mg
500 mg
$47.50
$128.80
$508.30
N0262 Naphazoline Hydrochloride
Naphazoline produces inotropic effects via α-adrenoceptor stimulation.

Endoh M, Schumann HJ. Naunyn Schmiedebergs Arch Pharmacol. 287:377-89 (1975).
25 g
100 g
$37.00
$129.40
N0263 Naphazoline Nitrate
10 g
25 g
100 g
$30.80
$67.80
$234.10
N0161 β-Naphthoflavone
5, 6 -Benzoflavone
An inducer of cytochrome P450 enzyme system. Protects chemical-induced carcinogenesis by enhancing the detoxification of carcinogens.

Callander RD, Mackay JM, Clay P. Mutagenesis. 10:517-22 (1995).
Anderson LM, Seetharam S. Cancer Res. 45:6384-9 (1985).
1 g
5 g
$38.50
$133.90
N0160 NAP
0.5 mg
1 mg
2.5 mg
$20.00
$34.00
$60.00
N0163 2-(1,8-Naphthyridin-2-ly)phenol
2-NP
It was shown to enhance IFN-g ability to inhibit the proliferation of human breast cancer and fibrosarcoma cells.

Lynch RA, Etchin J, Battle TE, Frank DA Cancer Res. 67: 1254-1261 (2007).
500 mg
1 g
5 g
$79.20
$132.00
$550.00
N0061 D-Naproxen
A non-steroidal anti-inflammatory agent found to significantly inhibit NNK activation in lung tissues.

Bouchard L, Castonguay A. Drug Metab. Disp. 21: 293-298 (1993).
5 g
25 g
50 g
$35.20
$122.90
$224.50
N0062 D,L-Naproxen
A non-steroidal anti-inflammatory agent found to significantly inhibit NNK activation in lung tissues.

Bouchard L, Castonguay A. Drug Metab. Disp. 21: 293-298 (1993).
10 g
25 g
100 g
$36.10
$80.90
$256.00
N0068 Naringenin
+4 oC The aglycone of naringin, a dietary flavonoid found in grapefruit juice. An effective anti-oxidant and antimutagen.

Guengerich FP, Kim DH. Carcinogenesis. 11:2275-2279 (1990).
Calomme M, Pieters L, Vlietinck A, Berghe D. Planta Med. 62:222-226 (1996).
5 g
10 g
25 g
$48.90
$65.10
$142.40
N0069 Naringin
A citrus bioflavonoid found to inhibit cytochrome P450 monooxygenase activity in mouse liver. It prevents toxin-induced cytoskeletal disruption and apoptotic liver cell death. In addition, it was found to have hypocholesterolemic effect by inhibiting HMG-CoA reductase and ACAT activities.

Ueng YF, Chang YL, Oda Y et al. Life Sci. 65:2591-2602 (1999).
Blankson H, Grotterod EM, Seglen PO. Cell Death Diff. 7:739-746 (2000).
Shin YW, Nok SH, Jeong TS et al. Int. J. Vit. Nutr. Res. 69:341-347 (1999).
25 g
100 g
$27.20
$81.40
N0075 Natamycin
Pimaricin
A polyene antifungal compound, shown to potentiate bleomycin activity against murine tumors.

Komiyama K, Umezawa I, Kuwano M et al. Gann. 74:602-6 (1983).
Brothers AM, Wyatt RD. Avian Dis. 44:490-7 (2000).
25 mg
50 mg
100 mg
$100.80
$168.00
$308.00
N0212 Nedaplatin
A platinum complex that has potent antineoplatic activity.

Yamada H, Uchida N, Maekawa R, Yoshioka T. Cancer Lett. 172:17-25 (2001).
Uchida N, Takeda Y, Kasai H. Anticancer Res. 18:3375-9 (1998).
10 mg
25 mg
50 mg
$115.40
$258.30
$461.00
N1822 Nefazodone Hydrochloride
An antidepressant acts by modifying serotonin transmission. It also exhibits analgesic effect in mice.
Eison AS, Eison MS, Torrente JR et al. Psychopharmacol Bull. 26:311-5 (1990).

Pick CG, Paul D, Eison MS. Pasternak GW. Eur J Pharmacol. 211:375-81 (1992).
Owens MJ, Ieni JR, Knight DL et al. Life Sci. 57:PL373-80 (1995).
1 g
5 g
25 g
$34.50
$147.90
$517.50
N1755 Neomycin sulfate
Antibacterial produced by Streptomyces fradiae.

Taborsky I, Nezval J, Smekal E, Janisch R. J Hyg Epidemiol Microbiol Immunol. 11:359-67 (1967).
Macdonald RH, Beck M. Clin Exp Dermatol. 8:249-58 (1983).
1 g
5 g
10 g
25 g
$10.20
$13.30
$15.30
$30.80
N1656 Neopterin
A prognostic marker for the progression of immunodefeciency.

Prommegger R, Winder B, Murr C et al. Ann Thorac Surg. 70:1861-4 (2000).
10 mg $34.20
N1757 Neostigmine Bromide
Prostigmine
An acetylcholine esterase inhibitor. It has protective effects against gastric carcinogenesis. It also may provide analgesia in patients with pain arising from neoplasia.

Tatsuta M, Iishi H, Baba M, Taniguchi H. Int J Cancer. 51:767-71 (1992).
Klamt JG, Dos Reis MP, Barbier neto J, Prado WA. Pain. 66:389-91 (1996).
250 mg
1 g
$17.70
$26.60
N1769 Nerolidol
It has inhibitory effects on carcinogenesis of the large bowel.

Warttenberg LW. Carcinogenesis. 12:151-2 (1991).
5 g
25 g
$18.50
$40.10
N1873 Nesiritide Acetate (BNP-32)
Nesiritide is a sterile, purified preparation of a new drug class, human B-type natriuretic peptide (hBNP), and is manufactured from E. coli using recombinant DNA technology.

Sun Z, Chen J, Yao H, Liu L, Wang J, Zhang J, Liu JN. Protein Expr Purif. 43:26-32 (2005).
Please inquire
N1976 Netilmicin Sulfate
1-N-Ethylsisomicin
A aminoglycoside antibiotic. It is a semisynthetic derivative of gentamycin.

Scuderi AC, Paladino GM, Marino C et al. Cornea. 22:468-72 (2003).
Adelman RD, Conzelman G, Spangler W et al. Curr Probl Clin Biochem. 9:166-82 (1979).
5 mg
10 mg
25 mg
$123.20
$184.80
$369.60
N1977 Neurokinin A (4-10)
A selective NK1 receptor agonist against tachykinin receptors.

Teixeira RM, Santos AR, Ribeiro SJ, Calixto JB, Rae GA, DeLima TC. Eur J Pharmacology 311: 7-14 (1996).
1 mg
2 mg
5 mg
$44.80
$76.16
$134.40
N1978 Neurokinin B
A peptide thought to be responsible for pre-eclampsia in women.

Page NM, Woods RJ, Gardiner SM, Lomthaisong K, Gladwell RT, Butlin DJ, Manyonda IT, Lowry PJ. Nature 405: 797-800 (2000).
1 mg
2 mg
5 mg
$38.40
$65.30
$115.20
N1979 Neuromedin
1 mg
2 mg
5 mg
$25.60
$43.60
$76.80
N1980 Neuromedin B, porcine
C52H73N15O12S            Mol Wt: 1132.3             [87096-84-2]
Neuromedin B and C are bombesin-like peptides. They have various physiological effects, including regulation of exocrine and endocrine secretions, smooth muscle contraction, feeding, blood pressure, blood glucose, body temperature and cell growth.

Ohki-Hamazaki H. Prog Neurobiol. 62:297-312 (2000).
1 mg
2 mg
5 mg
$51.20
$87.10
$153.60
N1981 Neuromedin C, porcine GRP (18-27)
C50H73N17O11S              Mol Wt: 1120.3            [81608-30-2] 1 mg $80.00
N1982 Neuromedin U, rat
A neuropeptide which affects smooth muscle. It was first isolated from porcine spinal cord.

Howard AD Et Al. Nature 406: 70-4 (2000).
1 mg
2 mg
5 mg
$108.80
$185.00
$326.40
N1984 Neuropeptide FF F-8-F-NH2
C54H76N14O102              Mol Wt: 1081.3            [99566-27-5] 5 mg
10 mg
25 mg
$120.00
$204.80
$360.00
N1985 Neuropeptide K, porcine
C175H284N52O52S              Mol Wt: 5980.6
Isolated from porcine spinal cord. It was shown to exert control over neural transmission.

Tatemoto K, Lundberg JM, Jornvall H, Mutt V. Biochem Biophys Res Commun 128: 947-53 (1985).
5 mg
10 mg
25 mg
$512.00
$870.40
$1,536.00
N1983 Neuropeptide Y (3-36), human
A neuropeptide thought to be associated with food intake.

Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE,
Low MJ, Ghatei MA, Cone RD, Bloom SR. Nature 418: 650-4 (2002).
0.5 mg
1 mg
2.5 mg
$108.80
$184.00
$326.40
N1987 Neuropeptide Y (13-36), human
0.5 mg
1 mg
2.5 mg
$97.60
$163.20
$288.00
N1986 Neuropeptide Y, human, rat
C189H285N55O57S              Mol Wt: 4271.7 5 mg
10 mg
25 mg
$512.00
$870.40
$1,536.00
N1988 γ-Neuropeptide, rabbit
When injected into the heart of a rabbit, a decrease in blood flow was induced.

Allen JM, Bircham PM, Edwards AV, Tatemoto K, Bloom SR. Regul Peptide 6: 247-53 (1983).
0.5 mg
1 mg
2.5 mg
$96.00
$163.20
$288.00
N1989 Neurotensin
A gut regulatory peptide that exerts a wide range of biological actions on gastrointestinal tissues. It has been shown to potentiate the proliferative effects of insulin on IMR90 human fibroblasts.

Scarpa RC, Carraway RE, Cochrane DE. Peptides. 25:1159-69 (2004).
Assimakopoulos SF, Vagianos CE, Zervoudakis G et al. Regul Pept. 120:185-93 (2004).
1 mg
2 mg
5 mg
$32.00
$54.40
$96.00
N1990 [Gln4] Neurotensin
1 mg
2 mg
5 mg
$32.00
$54.40
$96.00
N1991 [D-Trp11] Neurotensin
5 mg
10 mg
25 mg
$96.00
$163.20
$288.00
N1992 Neurotensin (1-11)
1 mg
2 mg
5 mg
$32.00
$54.40
$96.00
N1993 Neurotensin (9-13)
5 mg
10 mg
25 mg
$96.00
$163.20
$288.00
N1994 Neurotensin, frog
0.5 mg
1 mg
2.5 mg
$19.20
$32.00
$57.60
N1995 Neurotensin, guinea pig
1 mg
2 mg
5 mg
$32.00
$54.40
$96.00
N3310 Nicotinamide
A naturally occurring vitamin that is a protease inhibitor. Topical nicotinamide has demonstrated preventive activity against photo carcinogenesis in mice by elevating skin nicotinamide-adenine dinucleotide (NAD) content. It also has protective effects against lung and pancreatic carcinogenesis.

Gensler HL, Williams T, Huang AC, Jacobson EL. Nutr Cancer. 34:36-41 (1999).
Nikonova TV, Draudin-Krylenko VA, Bukin Iu V, Turusov VS. Eksp Onkol. 10:17-9 (1998).
Pour PM, Lawson T. J Natl Cancer Inst. 73:767-70 (1984).
50 g $46.10
N3213 Nidulal
A natural product isolated from Nidula candida. It induces differentaition of human HL-60 promyelocytic leukemia cells, and preferentially activates the transcription factor complex AP-1-mediated expression of secreted alkaline phosphatase in COS-7 cells.

Erkel G, Necker U, Anke T et al. J Antibiot (Tokyo) 49:1189-95 (1996).
0.5 mg $304.60
N3228 Nifedipine
2-8 oC 4-(2'nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine
C17H18N2O6      Mol.Wt.: 346.3             [21829-25-4]
Ca+2 channel blocker, induces apoptosis in human glioblastoma cells.

Miller RJ. Science. 235:46 (1987).
1 g
5 g
25 g
$30.80
$80.00
$230.50
N3422 Nifekalant Hydrochloride
A class III antiarrhythmic drug. It has been shown to be effective against ventricular tachyarrhythmias by inhibiting HERG channels in a voltage-dependent and frequency-dependent manner.

Kushida S, Ogura T, Komuro I et al. Eur J Pharmacol. 457:19-27 (2002).
Shiga T, Matsuda N, Fuda Y et al. J Cardiol. 39:159-64 (2002).
10 mg
25 mg
$80.10
$154.00
N3322 Niflumic acid
A NSAID, found to be a potent anion channel blocker.
White MM, Aylwin M. Mol. Pharm. 37:720-724 (1990).
25 g
100 g
$34.00
$61.10
N3520 Nifursol
Salfuride
An antibiotic used as a feed additive.

Callait MP, Granier C, Chauve C et al. Poult Sci. 81:1122-7 (2002).
Kowalski P, Oledzka I, Lamparczyk H. J Pharm Biomed Anal. 32:937-47 (2003).
25 g
100 g
$55.50
$154.00
N3225 Nigericin
A potassium ionophore, found to induce cell death and promote the maturation and release of IL-1β in lipopolysaccharide primed monocytes and macrophages. It also enhances rapamycin action.

Fang A, Wong GK, Demain AL. J Antibiot (Tokyo). 53:158-62 (2000).
Hentze H, Lin XY, Choi MS et al. Cell Death Differ. 10:956-68 (2003).
1 mg
5 mg
10 mg
$20.00
$48.70
$91.00
N3230 Nigrin b
-20 oC Nigrin b is a two chain type 2 ribosome-inactivating protein isolated from elder bark (Sambucus nigra L.). It inhibits protein synthesis by inactivation of mammalian ribosomes but not plant nor E. coli ribosomes.

Girbes T et al. Plant Mol. Biol. 22, 1181 (1993).
Batelli MG et al. Arch. Toxicol. 71, 360 (1997).
Olsnes S et al. J.Biol. Chem. 249, 803 (1993).
1 mg $230.50
N3450 Nimesulide
Inhibits prostaglandin synthetase (COX-2 inhibitor), and has anti-inflammatory activity. It induces apoptosis and inhibits carcinogenesis.

Huskisson EC. Clin Exp Rheumatol. 19:S21-5 (2001).
Kitayama W, Denda A, Okajima E. Carcinogenesis. 20:2305-10 (1999).
Hida T, Kozaki K, Muramatsu H. Clin Cancer Res. 6:2006-11 (2000).
Nakatsugi S, Ohta T, Kawamori T. Jpn J Cancer Res. 91:886-92 (2000).
5 g
10 g
25 g
$38.50
$69.30
$138.40
N3448 Nimodipine
A calcium channel antagonist.

Gupta MC, Garg SK, Das BP, Bhargava VK. Indian J Physiol Pharmacol. 47:347-51 (2003).
500 mg
1 g
5 g
$49.30
$86.30
$308.00
N3452 Nimustine Hydrochloride
1-(4-amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitrosourea, ACNU
DNA cross-linker used to treat malignant glioma.

Kono K, Takahashi JA, Ueba T. J. Neuro-Oncol. 56:101-108 (2002).
100 mg
500 mg
1 g
$34.00
$74.60
$101.70
9-Nitro-20(S)-camptothecin
See Camptothecin, 9-nitro-20(S)
N3278 7-Nitroindazole
A neuronal nitric oxide synthase (nNOS) inhibitor. It enhances amphetamine-evoked release, and kainic acid induced cholinergic neurotoxicity in the rat striatum.

Guevara BH, Cespedes GC, Cubeddu LX. Cell Mol Neurobiol. 22:827-34 (2002).
Nowak P, Brus R, Oswiecimska J et al. J Physiol Pharmacol. 53:251-63 (2002).
500 mg
1 g
5 g
$55.50
$74.00
$246.40
N3276 Nitroso(acetoxymethyl)methylamine
-20 oC Stable derivative of dimethylnitrosoamine metabolite, a potent carcinogen.

Frank N, Janzowski C, Wiessler M. Biochem. Pharm. 29:383-7 (1980).
Rice JSR, Wenk JM, Roller ML, Keefer LK. J. Nalt. Cancer Inst. 58:1531-35 (1977).
10 mg
50 mg
100 mg
$75.00
$224.90
$396.00
N3378 S-Nitrosoglutathione
An antioxidant that annihilates free radicals and promotes neuro protection via its c-GMP independent nitrosylation actions. It is also reported that S-nitrosoglutathione induces apoptosis in human adenocarcinoma cells in the presence of Cu and Ni ions.

Chiueh CC, Rauhala P. Free Radic Res. 31:641-50 (1999)
Ho Y S, Liu H L, Duh J S et al. Molecular Carcinogenesis. 26:201-11 (1999).
5 mg
10 mg
25 mg
$50.10
$84.60
$113.40
N3496 Nizatidine
A H2-receptor antagonist, found to be a potent inhibitor of gastric acid secretion.

Lin TM, Evans DC, Warrick MW et al. J Pharmacol Exp Ther. 239:406-10 (1986).
Abdel-Rahman SM, Johnson FK, Connor JD et al. J Pediatr Gastroenterol Nutr. 38:442-51 (2004).
5 g
10 g
$33.60
$56.00
N5210 Nociceptin
Orphanin FQ
The endogenous ligand for the opioid-receptor-like receptor 1. It mediates essential functions in the central and peripheral nervous systems.

Li N, Wei SY, Yu LC et al. Brain Res. 1025:67-74 (2004).
1 mg $161.30
N5211 Nocistatin
0.5 mg
1 mg
2.5 mg
$192.00
$326.40
$576.00
N5409 Nocodazole
Microtubule inhibitor.

Karbowski M, Spodnik JH, Teranishi Ma et al. J Cell Sci. 114:281-291 (2001).
Samson F, Donoso JA, Heller-Bettinger I et al. J Pharmacol Exp Ther. 208:411-7 (1979).
10 mg
50 mg
$95.00
$350.00
N5550 Nomilin
RT Nomilin is a natural product isolated from grapefruit seed. It is an inducer of Phase II detoxifying enzymes and inhibitor of chemcially induced carcinogenesis.

Maier V P, Hasegawa S, Bennett, R. D, Echols L.C. In: Citrus Nutrition and Quality, ed. by S. Nagy and J. A. Attaway, ACS Symposium Series 143, ACS, Washington, D.C. pp 63-81 (1980).
Lam LKT, Hasegawa S. Nutr. Cancer. 12:43-47 (1989).
Miller EG, Fanous R, Rivera-Hidalgo F et al. Carcinogenesis. 10:1535-1537 (1989).
25 mg
100 mg
500 mg
$75.10
$187.30
$655.70
N5652 Nonactin
C40H64O12              Mol Wt: 736.934             [6833-84-7]
A selective ionophore used in the determination of ammonium ions.

Karakus E, Pekyardimci S, Kilic E. Artif Cells Blood Substit Immobil Biotechnol. 34:523-34 (2006).
1 mg
5 mg
10 mg
$20.00
$40.00
$72.00
N5655 Nonoxynol, n=9
Polyoxynol nonylpheyl ether, a surfactant used as a vaginal contraceptive and condom luricant.

Van damme L. AIDS Read. 10:552-4. (2000).
Sonnenschein C, Soto AM. J Steroid Biochem Mol Biol. 65:143-50 (1998).
50 g
100 g
$30.80
$53.90
Noradrenaline
See Norepinephrine
N5669 Nordihydroguaiaretic acid
RT A naturally ocurring antioxidant and potent lipoxygenase inhibitor with antipromoter activity.

Nakadate T, Yamamoto S, Iseki H et al. Gann. 73:841-843 (1982).
500 mg
1 g
5 g
$51.80
$88.80
$332.70
N5766 Norepinephrine bitartrate
Norepinephrine activates protein kinases Erk1/2. It is cytotoxic to human promyelocytic leukemic HL-60 cells.

Lindquist JM, Fredriksson JM, Rehnmark S et al. J Biol Chem. 275:22670-7 (2000).
Kawase M, Motohashi N, Kurihara T et al. Anticancer Res. 18:1069-74 (1998).
500 mg
1 g
$69.30
$107.60
N5767 Norethindrone
Norethisterone
A synthetic progestin that possesses antiestrogenic effects. It is progestational in low dose and antiestrogenic in high dose. It has also been shown to cause a time-dependent loss of cytochrome P-450 when incubated in vitro with rat liver microsomal fractions and NADPH-generating systems.

White IN, Muller-Eberhard U. Biochem J. 166:57-64 (1997).
Tamaya T, Ishihara S, Motoyama T et al. Nippon Naibunpi Gakkai Zasshi. 51:1033-42 (1975).
250 mg
1 g
5 g
$39.50
$64.10
$246.40
Norethisterone
See Norethindrone
N5768 Norfloxacin
RT A fluorosquinolone antibacterial. 10 g
50 g
$56.20
$199.70
N5769 Norfloxacin Nicotinate
10 g
50 g
$55.50
$197.20
Norgestrel
See Levonorgestrel
N5778 Notoginsenoside R1
Active ingredient isolated from Panax notoginseng. It induces tissue-type plasminogen activator synthesis in cultured human umbilical vein endothelial cells.

Zhang W, Wojta J, Binder BR. Arterio Throm. 14:1040-1046 (1994).
5 mg
10 mg
25 mg
$94.90
$162.70
$318.60
N6020 NPF
1 mg
2 mg
5 mg
$102.40
$172.80
$307.20
N6076 N(p-Tosyl)-GPR-pNA
C26H34N8O7S              Mol Wt: 602.0 100 mg $536.00
N7604 NTB (Naltriben)
An opoid antagonist that has been shown to suppress alcohol intake in rats.

Krishnan-Sarin S, Portoghese PS, Li TK, Frohlich JC. Pharmcol Biochem Behav 52: 153-9 (1995).
0.5 mg
1 mg
2.5 mg
$70.40
$118.40
$211.20
N9874 Nystatin
An antifungal drug.

Patton LL, Bonito AJ, Shugars DA. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 92:170-9 (2001).
500 KU
1 MU
5 MU
$12.50
$14.70
$36.70
Alphabetized - N
 
 
   
 
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