| O0829 |
Ochratoxin A |
1 mg |
$58.20 |
| |
C20H18ClNO6 FW 403.81 m.p. 1690C [303-47-9] |
5 mg |
$253.10 |
| |
A toxic fungal metabolite and carcinogen. Inhibits phosphorylase |
|
|
| |
and mitochondrial respiration in rat liver. |
|
|
| |
Applegate KL, Chipley JR. Adv. Appl. Microbiol.16:97-109 (1973). |
|
|
| |
Meisner H, Chan S. Biochemistry. 13:2795-2800 (1974). |
|
|
| |
|
|
|
| O0978 |
Octaneuropeptide |
1 mg |
$120.50 |
| |
C41H74N12O11 FW 911.1 |
|
|
| |
|
|
|
| O0977 |
Octopamine HCl |
1 g |
$30.10 |
| |
C8H11NO2.HCl FW 189.64 [770-05-8] |
5 g |
$62.70 |
| |
Octopamine is a neuromodulator that occurs naturally in nervous tissues in |
25 g |
$250.90 |
| |
many species of animals. |
|
|
| |
Goaillard JM, Schulz DJ, Kilman VL et al. J Neurosci. 24:7063-73 (2004). |
|
|
| |
Roeder T, Seifert M, Kahler C et al. Arch Insect Biochem Physiol. 54:1-13 (2003). |
|
|
| |
|
|
|
| O1078 |
Octreotide Acetate |
1 mg |
$219.50 |
| |
Sandostatin |
5 x 1 mg |
$853.00 |
| |
C49H66N10O10S2.2C2H4O2 FW 1139.36 [79517-01-4] |
|
|
| |
Somatostatin analogue with antiproliferative effect. It is able to inhibit angiogenesis |
|
|
| |
induced by hepatocellular carcinoma in vivo, and Akt/PKB and telomerase activity |
|
|
| |
of SGC7901 cells. |
|
|
| |
Stockmann F, Creutzfeldt WZ. Gastroenterol. 26:665-75 (1988). |
|
|
| |
Jia WD, Ku GL, Sun HC et al. Hepatobiliary Pancreat Dis Int. 2:404-9 (2003). |
|
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| |
Gao S, Yu BP, Li Y et al. World J Gastroenterol. 9:2362-5 (2003). |
|
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| |
|
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|
| O1176 |
n-Octyl Caffeate |
5 mg |
$28.00 |
| |
Caffeic acid n-octyl ester, 3,4-dihydroxycinnamic acid n-octyl ester. |
25 mg |
$112.00 |
| |
C17H24O4 FW 292.37 |
|
|
| |
Antioxidant and supressor ofÊiNOS. Induces apoptosis in human leukemia U937 cells. |
|
|
| |
Etzenhouser B et al. Bioorg. Med. Chem. 9:199 (2001). |
|
|
| |
Hsiao G et al. Biochem. Pharmacol. 65:1383 (2003). |
|
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| |
Ujibe M et al. Biol. Pharm. Bull. 28:2338 (2005). |
|
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| |
|
|
|
| O1177 |
n-Octyl-3,4-Dimethylcaffeate |
5 mg |
$22.40 |
| |
3,4-Dimethylcaffeic acid n-octyl ester; 3,4-dimethoxycinnamic acid n-octyl ester |
25 mg |
$89.60 |
| |
C19H28O4 FW 320.42 |
|
|
| |
Derivative of n-octyl-caffeate. |
|
|
| |
|
|
|
| O1178 |
n-Octyl-3-methylcaffeate |
5 mg |
$28.00 |
| |
3-Methylcaffeic acid n-octyl ester;4-Hydroxy-3-methoxycinnamic acid n-octyl ester |
25 mg |
$112.00 |
| |
C18H26O4 FW 306.40 |
|
|
| |
Derivative of n-octyl-caffeate. |
|
|
| |
|
|
|
| O1179 |
n-Octyl-4-methylcaffeate |
5 mg |
$112.00 |
| |
4-Methylcaffeic acid n-octyl ester; 3-Hydroxy-4-methoxycinnamic acid n-octyl ester |
25 mg |
$448.00 |
| |
C18H26O4 FW 306.40 |
|
|
| |
Derivative of n-octyl-caffeate. |
|
|
| |
|
|
|
| O2144 |
Ofloxacin |
5 g |
$53.00 |
| |
C18H20FN3O4 FW 361.37 m.p. 250-2570C [82419-36-1] |
10 g |
$89.60 |
| |
A broad spectrum, fluorinated antibacterial quinolone. |
50 g |
$354.60 |
| |
Siebert G et al. Eur. J. Clin. Microbiol. 2:548 (1983). |
|
|
| |
|
|
|
| O2146 |
R-(+)-Ofloxacin Hemihydrate |
1 mg |
$89.70 |
| |
The optically active form of ofloxacin. |
5 mg |
$393.30 |
| |
|
10 mg |
$689.90 |
| |
|
|
|
| |
|
|
|
| O2145 |
Ofloxacin Hydrochloride |
5 g |
$45.60 |
| |
C18H20FN3O4.HCl FW 397.94 |
10 g |
$68.40 |
| |
|
50 g |
$273.30 |
| |
|
|
|
| |
|
|
|
| O4101 |
Okadaic Acid |
25 µg |
$95.10 |
| |
C44H68O13 FW 805.00 [78111-17-8] |
50 µg |
$174.00 |
| |
Non-phorbol type tumor promoter. It is also a potent inhibitor |
100 µg |
$298.50 |
| |
of protein phosphatases in numerous cell types. |
1 mg |
$1,956.10 |
| |
Suganuma M et al. Proc. Natl. Acad. Sci. USA 85:1768-1771 (1988). |
|
|
| |
Cohen P et al. Trends Biochem. Sci. 15: 98-102 (1990). |
|
|
| |
|
|
|
| O4102 |
Okadaic Acid Ammonium Salt |
25 µg |
$88.50 |
| |
C44H67O13.NH4 FW 822.04 [155716-06-6] |
100 µg |
$278.80 |
| |
Ammonium salt form of okadaic acid, with somewhat greater stability after it |
1 mg |
$2,151.60 |
| |
is put into organic solvents. |
|
|
| |
|
|
|
| |
|
|
|
| O4104 |
Okadaic Acid Sodium Salt |
25 µg |
$95.10 |
| |
C44H67O13.Na FW 827.0 |
100 µg |
$278.80 |
| |
Sodium salt form of okadaic acid, with somewhat greater stability after |
1 mg |
$2,151.60 |
| |
it is put into organic solvents. |
|
|
| |
|
|
|
| |
|
|
|
| O4417 |
Oleanolic Acid |
100 mg |
$50.40 |
| |
C30H48O3 FW 456.7 [508-02-1] |
500 mg |
$168.00 |
| |
Is a naturally occurring triterpenoid found in Phytolacca Americana and garlic. |
1 g |
$224.00 |
| |
Exhibits strong anti-HIV activity. Mechanism of action is the induction of iNOS |
|
|
| |
and of Cyclooxygenase 2. |
|
|
| |
Sultana, N. Journal of Enzyme Inhibition and Medicinal Chemistry (2008), 23(6), 739-756. |
|
|
| |
Rodriguez-Rodriguez, R. British Journal of Pharmacology (2008), 155(4), 535-546. |
|
|
| |
|
|
|
| O4533 |
Oligomycin |
1 mg |
$22.40 |
| |
C45H74O11 FW 791.06 [1404-19-9] |
5 mg |
$58.20 |
| |
A mixture of oligomycins A, B and C. Has antibiotic properties. |
10 mg |
$114.20 |
| |
Inhibits membrane bound mitochondrial ATPase and phosphoryl group transfer. |
|
|
| |
Nagamune H et al. Biochim. Biophys. Acta 1141:231-237 (1993). |
|
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| |
|
|
|
| |
|
|
|
| O4556 |
Olomoucine |
5 mg |
$108.40 |
| |
C15H18N6O FW 298.34 [101622-51-0] |
25 mg |
$472.20 |
| |
Potent selective and competitive inhibitor of cyclin-dependent kinases. |
100 mg |
$1,288.70 |
| |
Vesely J et al. Eur J Biochem. 224:771-86 (1994). |
|
|
| |
|
|
|
| |
|
|
|
| O4672 |
Olsalazine Sodium |
25 mg |
$44.80 |
| |
C14H8N2Na2O6 FW 346.2 [6054-98-4] |
100 mg |
$112.00 |
| |
A medicine used in the treatment of ulcerative colitis converted to 5-amino- |
250 mg |
$224.00 |
| |
salicylic acid in the colon. |
|
|
| |
Hao, Junming. Shijie Huaren Xiaohua Zazhi (2005), 13(19), 2392-2394. |
|
|
| |
|
|
|
| O4578 |
Oltipraz |
500 mg |
$155.90 |
| |
C8H6N2S3 FW 226.34 [64224-21-1] |
1 g |
$246.00 |
| |
An antischistosomiasis drug found to inhibit carcinogenesis. It is effective |
5 g |
$950.80 |
| |
against several chemically induced tumor models. Its mechanism of action is |
|
|
| |
believed to be the induction of phase II detoxifying enzymes resulting in diminished carcinogen-DNA binding. |
|
|
| |
Bueding E, Dolan P, Leroy JP. Res Commun Chem Pathol Pharmacol. 37:293-303 (1982). |
|
|
| |
Wattenberg LW, Bueding E. Carcinogenesis. 7:1379-81 (1986). |
|
|
| |
Kensler T, Styczynski P, Groopman J et al. J Cell Biochem Suppl. 16I:167-72 (1992). |
|
|
| |
|
|
|
| O4917 |
Omeprazole |
1 g |
$72.40 |
| |
C17H19N3O3S FW 345.42 [73590-58-6] |
5 g |
$258.20 |
| |
A proton pump inhibitor. |
10 g |
$344.40 |
| |
Faiss S, Scherubl H, Riecken EO, Wiedenmann B. Recent Results Cancer Res. 142:193-207 (1996). |
|
|
| |
|
|
|
| O5212 |
Ondansetron |
100 mg |
$77.60 |
| |
C18H20ClN3O.2H2O FW 365.86 [88614-01-4] |
500 mg |
$325.50 |
| |
A serotonin-3 (5-HT3) receptor antagonists, used to prevent radiosurgery-induced nausea and |
|
|
| |
vomiting and modulation of alcohol intoxiccation. |
|
|
| |
Seynaeve C, Verweij J, de Mulder PH. Anticancer Drugs. 2:343-55 (1991). |
|
|
| |
Swift RM, Davidson D, Whelihan W, Kuznetsov O. Biol Psychiatry. 40:514-21 (1996). |
|
|
| |
|
|
|
| O6132 |
Opioid receptor antagonist Ac-RFMWMK-NH2 |
1 mg |
$120.50 |
| |
C44H66N12O7S2 FW 939.2 |
|
|
| |
|
|
|
| O7116 |
Orexin-B, human |
1 mg |
$267.20 |
| |
Hypocretin-2 |
|
|
| |
C123H212N44O35S FW 2899.4 |
|
|
| |
A hypothalamic neuropeptide encoded by a single mRNA transcript that stimulates food intake. |
|
|
| |
Lee JH, Bang E, Chae KJ et al. Eur J Biochem. 266:831-9 (1999). |
|
|
| |
|
|
|
| O6845 |
Orlistat |
100 mg |
$56.40 |
| |
(S)-2-formylamino-4-methyl-pentanoic acid (S)-1-[[(2S,3S)-3- |
500 mg |
$150.50 |
| |
hexyl-4-oxo-2-oxetanyl]methyl]-dodecyl ester |
1 g |
$250.90 |
| |
C29H53NO5 FW 495.73 [96829-58-2] |
|
|
| |
A novel inhibitor of fatty acid synthase used in the treatment of obesity. As a result of it's |
|
|
| |
ability to halt fatty acid synthase, Orlistat halts tumor cell proliferation, induces tumor cell |
|
|
| |
apoptosis, and inhibits the growth of PC-3 tumors in nude mice. |
|
|
| |
Drent ML, van der Veen EA. Obes Res. 3 Suppl 4:623-25 (1995). |
|
|
| |
Kridel SJ, Axelrod F, Rozenkrantz N et al. Cancer Res. 64:2070-5 (2004). |
|
|
| |
|
|
|
| O6953 |
Ornidazole |
5 g |
$42.60 |
| |
Tiberal, Madelen |
50 g |
$308.00 |
| |
C7H10ClN3O3 FW 219.63 [16773-42-5] |
|
|
| |
Used to treat some protozoan infections. |
|
|
| |
Khrianin AA, Reshetnikov OV Antibiot Khimioter. 51:18-21 (2006). |
|
|
| |
|
|
|
| O7053 |
L-Ornithine Hydrochloride |
10 g |
$16.60 |
| |
C5H12N2O2.HCl FW 168.62 [3184-13-2] |
25 g |
$22.20 |
| |
A nonprotein amino acid. It is used in the body in the biosynthesis of L-arginine, |
100 g |
$52.50 |
| |
L-proline and polyamines. |
1 kg |
$324.40 |
| |
Barbul A. J Parenter Enteral Nutr. 10:227-238 (1986).
|
|
|
| |
Wasaki K, Mano K, Ishihara M et al. Biochem Int. 14:971-976 (1987).
|
|
|
| |
|
|
|
| |
Orphanin FQ (See nociceptin) |
|
|
| |
|
|
|
| O7218 |
Oseltamivir Phosphate |
10 mg |
$56.00 |
| |
C16H31N2O8P FW 410.4 {204255-11-8] |
25 mg |
$95.20 |
| |
An oral anti-viral drug for the treatment of uncomplicated influenza one year |
100 mg |
$252.00 |
| |
or older. Approved by the FDA to treat type A or B influenza. |
|
|
| |
Rayner, C. R. Journal of Clinical Pharmacology (2008), 48(8), 935-947. |
|
|
| |
Johnson, D. S. Art of Drug Synthesis (2007), 95-114. |
|
|
| |
|
|
|
| O7377 |
Osthole |
250 mg |
$56.40 |
| |
C15H16O3 FW 244.29 [484-12-8] |
1 g |
$156.80 |
| |
A coumarin isolated from Cnidium monnieri (L.) Cusson. It is an antiplatelet |
5 g |
$627.20 |
| |
agent that inhibits phosphoinositide breakdown. It also prevents anti-Fas |
|
|
| |
antibody-induced hepatitis in mice by affecting the caspase-3-mediated apoptotic pathway. |
|
|
| |
Teng CM, Ko FN, Wang JP et al. J Pharm Pharmacol. 43:667-9 (1991). |
|
|
| |
Okamoto T, Kawasaki T, Hino O. Biochem Pharmacol. 65:677-81 (2003). |
|
|
| |
|
|
|
| O8503 |
OVA(323-339) |
5 mg |
$511.80 |
| |
C74H120N26O25 FW 1773.9 |
|
|
| |
|
|
|
| |
|
|
|
| O8500 |
Ovalbumin(257-264) antigen peptide |
1 mg |
$120.50 |
| |
C45H74N10O13 FW 963.2 |
|
|
| |
|
|
|
| |
|
|
|
| O9302 |
Oxacillin Sodium Monohydrate |
1 g |
$27.70 |
| |
C19H18N3NaO5S.H2O FW 441.44 [7240-38-2] |
5 g |
$69.00 |
| |
A member of the penicillin class of antibiotics. |
25 g |
$276.00 |
| |
Kirby WM, Rosenfeld LS, Brodie J. JAMA. 181:739-44 (1962). |
|
|
| |
|
|
|
| O9201 |
Oxaliplatin |
5 mg |
$77.60 |
| |
C8H14N2O4Pt FW 397.29 [61825-94-3] |
25 mg |
$301.40 |
| |
A novel platinum analogue which has wide spectrum anti-cancer activity. It is |
100 mg |
$946.70 |
| |
found to be more active against human melanoma cell lines, and has better |
|
|
| |
biochemical, pharmacological and cytotoxic properties than cisplatin and carboplatin. |
|
|
| |
Cassidy J. Int J Clin Pract. 54:399-402 (2000). |
|
|
| |
Mohammed MQ, Retsas S. Anticancer Drugs. 11:859-63 (2000). |
|
|
| |
|
|
|
| O9210 |
Oxcarbazepine |
1 g |
$41.40 |
| |
C15H12N2O2 FW 252.27 [28721-07-5] |
5 g |
$131.20 |
| |
A second-generation antiepileptic drug. It inhibits CYP2C19 and induces |
25 g |
$482.90 |
| |
CYP3A4 and CYP3A5 systems. Studies suggest that the anticonvulsant |
|
|
| |
activity of oxcarbazepine is mediated via the blocking of neuronal ion channels. |
|
|
| |
Carrazana E, Mikoshiba I. J Pain Symptom Manage. 25:S31-5 (2003). |
|
|
| |
Bang L, Goa K. Paediatr Drugs. 5:557-73 (2003). |
|
|
| |
|
|
|
| O9322 |
Oxfendazole |
10 g |
$48.40 |
| |
C15H13N3O3S FW 315.35 [53716-50-0] |
25 g |
$103.50 |
| |
An anthelmintic agent. |
100 g |
$324.40 |
| |
Corwin RM. Am J Vet Res. 38:465-7 (1977). |
|
|
| |
|
|
|
| O9334 |
Oxibendazole |
5 g |
$48.40 |
| |
C12H15N3O3 FW 249.27 [20559-55-1} |
10 g |
$82.90 |
| |
An anthelmintic agent. It has been shown to be effective in killing Trichinella |
25 g |
$172.50 |
| |
spiralis in mice, and histotrophic larvea and adult parasites in calves. |
|
|
| |
Karunakaran CS, Denham DA. J Parasitol. 66:929-32 (1980). |
|
|
| |
Theodorides VJ, DiCuollo CJ, Nawalinski T et al. Am J Vet Res. 38:809-14 (1977). |
|
|
| |
|
|
|
| O9234 |
Oxiconazole Nitrate |
1 g |
$55.20 |
| |
C18H14Cl4N4O4 FW 492.15 [64211-46-7] |
5 g |
$165.60 |
| |
An antifungal agent. |
25 g |
$551.90 |
| |
Polak A. Arzneimittelforschung. 32:17-24 (1982). |
|
|
| |
|
|
|
| O9256 |
16-Oxocafestol |
25 mg |
$119.80 |
| |
C18H24O2 FW 284.40 m.p. 168-1720C [108664-99-8] |
50 mg |
$208.80 |
| |
Synthetic derivative of cafestol. |
100 mg |
$359.90 |
| |
|
500 mg |
$1,170.10 |
| |
|
|
|
| |
|
|
|
| O9257 |
16-Oxokahweol |
10 mg |
$143.90 |
| |
C19H22O2 FW 282.39 m.p. 180-1830C [108664-99-9] |
25 mg |
$307.10 |
| |
Synthetic derivative of kahweol. |
50 mg |
$522.60 |
| |
|
100 mg |
$887.00 |
| |
|
|
|
| |
|
|
|
| O9398 |
Oxymetazoline Hydrochloride |
5 g |
$82.90 |
| |
C16H24N2O.HCl FW 296.84 [2315-02-8] |
25 g |
$303.60 |
| |
An a-adrenoceptor stimulant. |
|
|
| |
Sanders J, Miller DD, Patil PN. J Pharmacol Exp Ther. 195:362-71 (1975). |
|
|
| |
|
|
|
| |
|
|
|
| O9396 |
Oxytetracycline |
10 g |
$16.60 |
| |
C22H24N2O9 FW 460.43 [79-57-2] |
50 g |
$62.20 |
| |
An antibiotic. It impairs mitochondrial protein synthesis resulting in |
100 g |
$115.90 |
| |
proliferation arrest in s.c. and Zajdela tumor cells. Zajdela mitochondrial tumor |
|
|
| |
cells cease dividing after a few generations, which is preceded by reduction of cytochrome c oxidase |
|
|
| |
activity of the tumor cells. |
|
|
| |
van den Bogert C, Dontje BH, Wybenga JJ et al. Cancer Res. 41:1943-7 (1981). |
|
|
| |
Kroon AM, Dontje BH, Van den Bogert C. Cancer Res. 43:2247-51 (1983) |
|
|
| |
|
|
|
| O9397 |
Oxytetracycline Hydrochloride |
10 g |
$16.60 |
| |
C22H24N2O9.HCl FW 496.93 [2058-46-0] |
50 g |
$62.20 |
| |
|
100 g |
$110.40 |
| |
|
|
|
| O9497 |
Oxytocin |
5 mg |
$120.50 |
| |
C43H66N12O12S2 FW 1007.2 [50-56-6] |
25 mg |
$464.10 |
| |
Oxytocin has shown the ability to induce contractions and milk production in rats |
100 mg |
$1,568.00 |
| |
Pederson C, Prange Ar. PNAS 76(12); 6661-6665 (1979) |
1 g |
$4,335.30 |
| |
|
|
|
