| P0001 |
P1 |
0.5 mg |
$50.20 |
| |
C39H63N11O13 FW 894.0 |
1 mg |
$86.00 |
| |
|
2.5 mg |
$150.50 |
| |
|
|
|
| P0055 |
P55-TNFR |
1 mg |
$86.00 |
| |
C57H95N15O22 FW 1342.48 |
2 mg |
$146.90 |
| |
|
5 mg |
$258.00 |
| |
|
|
|
| P0075 |
P75-TNFR |
1 mg |
$86.00 |
| |
C53H85N15O156S1 FW 1204.42 |
2 mg |
$146.90 |
| |
|
5 mg |
$258.00 |
| |
|
|
|
| P0005 |
PACAP (1-27), human, ovine, rat |
0.5mg |
$164.90 |
| |
C142H224N40O39S1 FW 3147.68 |
1 mg |
$279.60 |
| |
|
2.5mg |
$494.60 |
| |
|
|
|
| |
|
|
|
| P0006 |
PACAP (1-38), human, ovine, rat |
0.5mg |
$222.20 |
| |
C203H331N63O53S1 FW 4534.36 |
1 mg |
$378.10 |
| |
|
2.5mg |
$666.60 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| P0007 |
PACAP (6-27), human, ovine, rat |
0.5mg |
$121.90 |
| |
C203H331N63O65S FW 4534.4 |
1 mg |
$207.90 |
| |
|
2.5 mg |
$365.60 |
| |
|
|
|
| |
|
|
|
| P0008 |
PACAP(6-38), human, ovine, rat |
0.5mg |
$207.90 |
| |
Pituitary adenylate cyclase activating peptide |
1 mg |
$353.00 |
| |
C203H331N63O65S FW 4534.4 [137061-48-4] |
2.5mg |
$623.60 |
| |
A hypothalamic peptide that affects anterior pituitary cell function. It also plays |
|
|
| |
a key role in the embryogenesis of brain, protection of brain nerve cells from |
|
|
| |
ischemia-induced death, injuring and apoptosis. |
|
|
| |
Chepurnov SA, Chepurnova NE, Ponomarenko AA et al. Usp Fiziol Nauk. 30:3-20 (1999). |
|
|
| |
Arbogast LA, Voogt JL. Brain Res. 655:17-24 (1994). |
|
|
| |
|
|
|
| P0009 |
PACAP 38, frog |
0.5mg |
$250.90 |
| |
C204H333N63O53S FW 4548.38 |
1 mg |
$426.50 |
| |
|
2.5mg |
$752.60 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| P0010 |
PACAP-Related Peptide (PRP), human |
0.5mg |
$179.20 |
| |
C139H229N41O42 FW 3146.62 |
1 mg |
$304.60 |
| |
|
2.5mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| P0011 |
PACAP-Related Peptide (PRP), rat |
0.5mg |
$179.20 |
| |
C148H242N42O45S1 FW 3361.9 |
1 mg |
$304.60 |
| |
|
2.5mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| P0092 |
Paclitaxel, (Natural), 99% |
1 mg |
$22.40 |
| |
C47H51NO14 FW 853.91 m.p. 213-2160C [33069-62-4] |
5 mg |
$39.20 |
| |
Natural diterpenoid isolated from the stem bark of the Pacific yew tree |
25 mg |
$89.60 |
| |
(Taxus brevifolia Nutt.). It promotes the assembly of stable microtubules and inhibits |
100mg |
$201.60 |
| |
the disassembly process of microtubules to tubulin. |
|
|
| |
Wani MC, Taylor HL, Wall ME et al. J. Am. Chem. Soc. 93:2325 (1971). |
|
|
| |
SuffnessM,CordellGA.Antitumor Alkaloids.In:TheAlkaloids.ChemistryandPharmacology,Brossi |
|
|
| |
Ed.; Acad Pr: N Y, Vol. XXV, pp. 3-355 (1985). |
|
|
| |
Manfredi JJ, Horwitz SB. Pharmacol. Ther. 25:83 (1984). |
|
|
| |
|
|
|
| P0093 |
Paclitaxel (Semi-synthetic) |
5 mg |
$35.80 |
| |
C47H31NO14 FW 853.9 |
25 mg |
$84.00 |
| |
A natural diterpenoid originally isolated from the stem bark of Taxus brevifolia. |
|
|
| |
It promotes the assembly of stable microtubules and inhibits the disassembly process |
|
|
| |
of microtubules to tubulin by calcium ions and by low temperature. Taxol was shown to |
|
|
| |
have activity against cancers, such as P388 and L1210 leukemia, B16 melanoma, WM-256 |
|
|
| |
carcinosarcoma, Sarcoma 180, Lewis lung tumor, and several xenografts of human tumors |
|
|
| |
including MX-1 mammary, LX-1 l |
|
|
| |
Wani, M. C., Taylor, H. L., Wall, M. E., Coggon, P., McPhail, A. T. J. Am. Chem. Soc. 93:2325 (1971). |
|
|
| |
|
|
|
| P0218 |
Paeoniflorin |
1 mg |
$68.90 |
| |
C23H28O11 FW 480.46 [23180-57-6] |
5 mg |
$249.80 |
| |
Paeoniflorin is a glycoside isolated from the root of Paeonia lactiflora. It has |
10 mg |
$364.80 |
| |
been used as an anticonvulsant and has hypoglycemic effect. It reverses guanethidine- |
|
|
| |
induced hypotension by activating the central adenosine A1 receptors in the brain. |
|
|
| |
Abel-Hafez AA, Meselgy MR, Nakamura N et al.Chem.Pharm.Bull (Tokyo).46:1486-1487 (1998). |
|
|
| |
Hsu FL, Lai CW, Cheng JT. Planta Med. 63:323-325 (1997). |
|
|
| |
Cheng JT, Wang CJ, Hsu FL. Clin. Ecp. Pharmacol Physiol. 26:815-816 (1999). |
|
|
| |
|
|
|
| P0219 |
Paeonol |
1 g |
$27.40 |
| |
C9H10O3 FW 166.17 [552-41-0] |
5 g |
$98.80 |
| |
Active ingredient isolated from Paeonia suffruticosa Andr. Its pharmacologic |
|
|
| |
functions include anti-inflammatory, antiaggregatory, and anti-ischemia |
|
|
| |
reperfusion damage and anti-lipid peroxidation effects. |
|
|
| |
Harada M, Yamashita A, Aburada M. J Pharm Soc Japan 92:750-756 (1972). |
|
|
| |
Hirai A, Terano T, Hamazaki T et al. Throm Res. 31:29-40 (1983). |
|
|
| |
Zhang WG, Zhang ZS. Acta Pharm Sinica 29:145-148 (1994). |
|
|
| |
|
|
|
| P0144 |
Paliperidone |
25 mg |
$50.40 |
| |
C23H27FN4O3 FW 426.48 [144598-75-4] |
100mg |
$143.40 |
| |
It is indicated in the treatment of schizophrenia, as well as manic and mixed |
500mg |
$573.40 |
| |
episodes occurring in conjunction with Bipolar I Disorder, and depression. |
|
|
| |
Narasimhan, M. Expert Review of Clinical Pharmacology (2008), 1(6), 737-744. |
|
|
| |
Marino, J. Pharmacotherapy (2008), 28(10), 1283-1298. |
|
|
| |
|
|
|
| P0245 |
Palmatine Chloride Hydrate |
1 g |
$30.90 |
| |
C21H22NO4.Cl.xH2O FW 387.86 [171869-95-7] |
5 g |
$77.60 |
| |
Palmatine is a protoberberine alkaloid isolated from medicinal herbs such as |
10 g |
$129.20 |
| |
Coptis chinensis Franch. It is a selective toposomerase I and II poison. The sedative |
|
|
| |
effect of palmatine is related to its ability to inhibit dopamine biosynthesis. |
|
|
| |
Palmatine is a vasodilator that reduces [Ca2+]. |
|
|
| |
Sanders MM, Liu AA, Li TK et al. Biochem. Pharmacol. 56:1157-1166 (1998). |
|
|
| |
Pilch DS, Yu C, Makhey D et al. Biochemistry. 36:12542-12553 (1997). |
|
|
| |
Shin JS, Kim EI, Kai M, Lee MK. Neurochem. Res. 25:363-368 (2000). |
|
|
| |
Hsieh MT, Su SH, Tsai HY et al. Jpn. J.Pharmacol. 61:1-5 (1993). |
|
|
| |
Chang YL, Usami S, Hsieh MT, Jiang MJ. Life Sci. 64:597-606 (1999). |
|
|
| |
|
|
|
| P0145 |
Palmitoyl-DL-carnitine Chloride |
100mg |
$48.40 |
| |
C23H45NO4.HCl FW 436.1 [6865-14-1] |
500mg |
$215.30 |
| |
A specific protein kinase C inhibitor. It inhibits 12-O-tetra decanoyl-phorbol-13-acetate (TPA) |
|
|
| |
enhanced transformation in BALB/3T3 cells. |
|
|
| |
Semba M, Ini N. Toxicol Lett. 51:7-12 (1990). |
|
|
| |
|
|
|
| P0146 |
Palmitoyl-L-carnitine Chloride |
5 mg |
$74.90 |
| |
C23H45NO4.HCl FW 436.1 [18877-64-0] |
10 mg |
$130.90 |
| |
Protein kinase inhibitor. |
|
|
| |
Butler AP, Mar PK, McDonald FF, Ramsay RL. Exp Cell Res. 194:56-61 (1991). |
|
|
| |
|
|
|
| P0049 |
Pamidronate Disodium |
10 mg |
$37.50 |
| |
C3H9NNa2O7P2.5H2O FW 279.03 [57248-88-1] |
50 mg |
$152.20 |
| |
Calcium metabolism regulator. |
100mg |
$286.70 |
| |
Man Z, Otero AB, Rendo P et al. Lancet. 335:663 (1990). |
|
|
| |
Fitton A, McTavish D. Drugs. 41:289-318 (1991). |
|
|
| |
|
|
|
| P0253 |
Panaxadiol |
5 mg |
$109.30 |
| |
C30H52O3 FW 460.74 [19666-76-3] |
10 mg |
$189.80 |
| |
Sapogenin isolated from Panax ginseng. |
25 mg |
$379.50 |
| |
|
|
|
| |
|
|
|
| P0254 |
Panaxatriol |
5 mg |
$109.30 |
| |
C30H52O4 FW 476.73 |
10 mg |
$189.80 |
| |
Sapogenin isolated from Panax ginseng. |
25 mg |
$379.50 |
| |
|
|
|
| |
|
|
|
| P0350 |
Pancreatic Polypeptide, avian |
0.5 mg |
$164.90 |
| |
C190H283N53O58 FW 4237.69 |
1 mg |
$279.60 |
| |
|
2.5 mg |
$494.60 |
| |
|
|
|
| |
|
|
|
| P0351 |
Pancreatic Polypeptide, rat |
0.5 mg |
$179.20 |
| |
C195H298N58O57S FW 4398.9 [90419-12-8] |
1 mg |
$304.60 |
| |
A gut hormone released from the pancreas in response to ingestion of food. It |
2.5 mg |
$537.60 |
| |
has been found to cause a sustained decrease in both appetite and food intake. |
|
|
| |
Batterham RL, Le Roux CW, Cohen MA et al. J Clin Endocrinol Metab. 88:3989-92 (2003). |
|
|
| |
|
|
|
| P0353 |
Pancreatic Polypeptide, human |
0.5 mg |
$121.90 |
| |
C185H287N53O54S2 FW 4181.7 [75976-10-2] |
1 mg |
$207.90 |
| |
|
2.5 mg |
$365.60 |
| |
|
|
|
| |
|
|
|
| P0352 |
Pancreastatin, porcine |
0.5 mg |
$430.10 |
| |
C214H330N68O76S FW 5103.4 |
1 mg |
$731.10 |
| |
A regulatory peptide with a general inhibitory effect on secretion. Inhibits |
2.5 mg |
$1,290.20 |
| |
DNA and protein synthesis by producing NO in HTC rat hepatoma cells, and |
|
|
| |
modulates insulin signaling in rat. |
|
|
| |
Gonzalez-Yanes C, Sanchez-Margalet V. Diabetes. 49:1288-94 (2000). |
|
|
| |
Sanchez-Margalet V, Gonzalez-Yanes C, Najib S. J Hepatol. 35:80-5 (2001). |
|
|
| |
|
|
|
| P0252 |
Pancuronium Bromide |
10 mg |
$39.20 |
| |
C35H60Br2N2O4 FW 732.67 [15500-66-0] |
50 mg |
$128.80 |
| |
A muscle relaxant which acts as a competitive acetycholine antagonist on |
100 mg |
$224.00 |
| |
neuromuscular junctions. |
250 mg |
$420.00 |
| |
Stankov-Jovanovic, V. Analytical and Bioanalytical Chemistry (2006), 385(8), 1462-1469. |
|
|
| |
Delogu, G. Acta Anaesthesiologica Scandinavica (2003), 47(9), 1138-1144. |
|
|
| |
|
|
|
| P0255 |
Pantoprazole |
100mg |
$34.50 |
| |
C16H15F2N3O4S FW 383.37 [102625-70-7] |
500mg |
$99.50 |
| |
A proton pump inhibitor. Inhibits vesicular gastric H+/K(+)-ATPase under acid |
1 g |
$165.60 |
| |
transporting conditions by accumulating in the acid space generated by the pump. |
|
|
| |
It has an inhibitory effect on acid secretion. |
|
|
| |
Krusekopf S, Roots I, Hildebrandt AG et al. Xenobiotica. 33:107-18 (2003). |
|
|
| |
Shin JM, Besancon M, Simon A et al. Biochim Biophys Acta. 1148:223-33 (1993). |
|
|
| |
|
|
|
| P0256 |
Pantoprazole Sodium |
1 g |
$34.50 |
| |
C16H15F2N3NaO4S FW 405.36 [138786-67-1] |
5 g |
$117.40 |
| |
Antiulcerative. |
25 g |
$414.00 |
| |
|
|
|
| P0260 |
Papain Inhibitor |
5 mg |
$43.00 |
| |
C19H29N7O6 FW 451.49 |
10 mg |
$73.50 |
| |
|
25 mg |
$129.00 |
| |
|
|
|
| P0268 |
Parasin I |
0.5 mg |
$136.20 |
| |
C82H154N34O24 FW 2000.36 |
1 mg |
$231.20 |
| |
|
2.5 mg |
$408.60 |
| |
|
|
|
| P0269 |
Parathyroid Hormone (1-34), bovine |
0.5 mg |
$179.20 |
| |
Teriparatide |
1 mg |
$304.60 |
| |
C183H288N54O50S2 FW 4108.7 |
2.5 mg |
$537.60 |
| |
A hormone shown to increase bone mass in a variety of animals and humans with osteoporosis. |
|
|
| |
Frolik CA, Black EC, Cain RL et al. Bone. 33:372-9 (2003). |
|
|
| |
|
|
|
| P0370 |
Paromomycin Sulphate |
1 g |
$50.20 |
| |
C23H45N5O14.H2SO4 FW 713.71 [1263-89-4] |
5 g |
$163.10 |
| |
A aminoglycoside antibiotic. |
25 g |
$551.90 |
| |
Konno T, Takahashi T, Muto A et al. Nucleic Acids Res Suppl. (3):235-6 (2003). |
|
|
| |
Lando D, Cousin MA, Ojasoo T et al. Eur J Biochem. 66:597-606 (1976). |
|
|
| |
|
|
|
| P0297 |
Paroxetine Hydrochloride |
100mg |
$115.50 |
| |
C19H20FNO3.HCl.1/2H2O FW 374.84 [110429-35-1] |
500mg |
$425.00 |
| |
A potent selective 5-hydroxytryptamine reuptake inhibitor used as a treament of |
1 g |
$736.30 |
| |
major depression. |
|
|
| |
Johnson AM. Int. Clin. Psych. 6:Suppl 4:5-24 (1992). |
|
|
| |
|
|
|
| P0270 |
Parthenolide |
25 mg |
$39.20 |
| |
C15H20O3 FW 248.32 [20554-84-1] |
100mg |
$95.20 |
| |
Sesquiterpene lactone and active ingredient of feverfew. Anti-inflammatory |
250mg |
$218.40 |
| |
agent. Induces apoptosis and cell necrosis. Suppresses NF-kappaB activity. |
|
|
| |
Pozarowski P et al Cytometry 54:118-124 (2003). |
|
|
| |
Wen J et al J. Biol. Chem. 277:38954-38964 (2002). |
|
|
| |
|
|
|
| P0278 |
Patulin |
1 mg |
$24.60 |
| |
Clavacin, clavatin, penicidin |
5 mg |
$94.10 |
| |
C7H6O4 FW 154.12 [149-29-1] |
10 mg |
$172.50 |
| |
Produced by a number of fungi species of Aspergillus and Penicillium. |
|
|
| |
It has anti-bacterial, carcinogenic and mutagenic activities. |
|
|
| |
Birkinshaw M et. Al. Lancet 245:625 (1943). |
|
|
| |
Dickens Brit. Med. Bull. 20:96 (1964). |
|
|
| |
|
|
|
| P0392 |
Paxilline |
5 mg |
$132.20 |
| |
C27H33NO4 FW 435.56 [57186-25-1] |
10 mg |
$241.90 |
| |
A tremorgenic indole alkaloid that selectively blocks |
|
|
| |
high-conductance Ca2+-activated K+-channels. |
|
|
| |
Sanchez M et al Neuropharmacology 35:963 (1996). |
|
|
| |
Young C et al Curr. Genet. 33:368 (1998). |
|
|
| |
|
|
|
| P0398 |
Pazufloxacin Mesylate |
500mg |
$124.20 |
| |
C16H15FN2O4.CH3SO3H FW 414.41 [163680-77-1] |
1 g |
$179.40 |
| |
A fluoroquinolone antimicrobial agent. It has a broad spectrum of activity |
5 g |
$662.40 |
| |
and potent activity against gram-positive and gram-negative bacteria. |
|
|
| |
Fukuoka Y, Ikeda Y, Yamashiro Y et al. Antimicrob Agents Chemother. 37:384-92 (1993). |
|
|
| |
Muratani T, Inoue M, Mitsuhashi S. Antimicrob Agents Chemother. 36:2293-303 (1992). |
|
|
| |
|
|
|
| P1622 |
Pefloxacine Mesylate |
5 g |
$34.50 |
| |
Pefloxacine Methansulfonate dihydrate |
25 g |
$117.40 |
| |
C17H20FN3O3.CH3SO3H.2H2O FW 465.50 [149676-40-4] |
100 g |
$172.50 |
| |
A fluoroquinolone antimicrobial agent. It was found to inhibit cell growth |
|
|
| |
of normal hematopoietic progenitor cells and leukemic cell lines. |
|
|
| |
Kondo H, Sakamoto F, Kawakami K, Tsukamoto G. J Med Chem. 31:221-5 (1988). |
|
|
| |
Somekh E, Douer D, Shaked N, Rubinstein E. J Pharmacol Exp Ther. 248:415-8 (1989). |
|
|
| |
|
|
|
| P1625 |
Peganine |
10 mg |
$124.20 |
| |
C11H12N2O FW 188.23 [6159-55-3] |
25 mg |
$245.60 |
| |
Peganine is an alkaloid isolated from Peganum harmala L. It has anti-cholinesterase activity. |
100mg |
$717.60 |
| |
Tuliaganov N, Sadritdinov FS, Suleimanova GA. Farmakol Toksikol. 49:37-40 (1986). |
|
|
| |
|
|
|
| P1849 |
Pemetrexed |
100mg |
$45.00 |
| |
|
250mg |
$82.00 |
| |
is a chemotherapy drug used for the treatment of pleural mesothelioma as well |
1 g |
$240.00 |
| |
as non-small cell lung cancer. |
|
|
| |
Hanauske, Axel-R, European Journal of Cancer (2008), 44(16), 2444-2452 |
|
|
| |
|
|
|
| P1754 |
Penciclovir |
100mg |
$62.90 |
| |
C10H15N5O3 FW 253.26 [39809-25-1] |
500mg |
$268.60 |
| |
Nucleoside analog that blocks DNA replication. |
1 g |
$402.90 |
| |
Shaw T, Amor P, Civitico G, Boyd M, Locarnini S. Antimicrob Agents Chemother. 38:719-23 (1994). |
|
|
| |
Earnshaw DL, Bacon TH, Darlison SJ et al. Antimicrob Agents Chemother. 36:2747-57 (1992). |
|
|
| |
|
|
|
| P1753 |
Penicillamine |
1 g |
$20.70 |
| |
C5H11NO2S FW 149.21 [52-67-5] |
5 g |
$68.90 |
| |
Exogenous NOS modulator, found to inhibit urease activity. |
25 g |
$275.40 |
| |
Chen JX, Berry LC, Tanner M, et al. J Cell Physiol.186:116-23 (2001). |
|
|
| |
Sissons CH, Yakub S. Oral Microbiol Immunol. 15:317-324 (2000). |
|
|
| |
|
|
|
| P1854 |
Penicillic acid |
5 mg |
$40.30 |
| |
C8H10O4 FW 170.16 [90-65-3] |
10 mg |
$71.70 |
| |
Anibiotic mycotoxin produced by various strains of Penicillium and Aspergillu. |
50 mg |
$300.20 |
| |
It has been found in corn and tabacco. Induces DNA single-strand breaks. |
|
|
| |
Keblys M, Bernhoft A, Hofer CC, Morrison E, Larsen HJ, Flaoyen A Mycopathologia 158:317-24 (2004) |
|
|
| |
|
|
|
| P1852 |
Penicillin G procaine |
10 g |
$13.90 |
| |
C29H38N4O6S.H2O FW 588.73 [6130-64-9] |
25 g |
$19.40 |
| |
Semisynthetic antibiotic. |
100 g |
$55.20 |
| |
|
|
|
| P1853 |
Penicillin V Potassium |
10 g |
$16.60 |
| |
C16H17KN2O5S FW 388.48 [132-98-9] |
25 g |
$27.70 |
| |
A bactericidal against penicillin-susceptible microorganisms during the stage of |
100 g |
$69.00 |
| |
active multiplication. It produces its effect by inhibiting biosynthesis of cell-wall mucopeptide. |
|
|
| |
Spitzer TQ. Harris BA. South Med J. 70:41-2 (1977). |
|
|
| |
Bolme P, Eriksson M. Acta Paediatr Scand. 65:253-6 (1976). |
|
|
| |
|
|
|
| P1952 |
Penitrem A |
1 mg |
$44.80 |
| |
Tremortin A |
5 mg |
$215.00 |
| |
C37H44ClNO6 FW 634.2014 [12627-35-9] |
|
|
| |
AĘtremorgenic indole alkaloid. Inhibits high-conductance Ca2+-activated K+ channels. |
|
|
| |
Knaus HG Biochemistry 33:5819-5828 (1994). |
|
|
| |
|
|
|
| P1955 |
Pentagastrin |
1 mg |
$78.80 |
| |
C37H50N7O9S1 FW 768.79 |
2 mg |
$134.40 |
| |
|
5 mg |
$236.50 |
| |
|
|
|
| P1764 |
Pep-1 |
0.5 mg |
$86.00 |
| |
C37H50N7O9S1 FW 768.79 |
1 mg |
$146.90 |
| |
|
2.5 mg |
$258.00 |
| |
|
|
|
| P1860 |
Pepaglinide |
100mg |
$72.80 |
| |
C27H35N2O4 FW 452.59 [135062-02-1] |
250mg |
$140.00 |
| |
is for the treatment of type II diabetes. |
1 g |
$448.00 |
| |
Sunaga, Yasuhiro, European Journal of Pharmacology (2001), 431(1), 119-125. |
|
|
| |
|
|
|
| P1765 |
Peptide Standard 1 |
0.5 mg |
$86.00 |
| |
C98H144N25O26S2 FW 2152.52 |
1 mg |
$146.90 |
| |
|
2.5 mg |
$258.00 |
| |
|
|
|
| P1766 |
Peptide B, bovine |
0.5 mg |
$114.70 |
| |
C163H239N39O53S2 FW 3657.08 |
1 mg |
$195.30 |
| |
|
2.5 mg |
$344.10 |
| |
|
|
|
| P1767 |
Peptide F, bovine |
1 mg |
$236.50 |
| |
C163H239N39O53S2 FW 3657.08 |
2 mg |
$401.40 |
| |
|
5 mg |
$709.60 |
| |
|
|
|
| |
|
|
|
| P1760 |
Peptide T |
1 mg |
$62.70 |
| |
C35H55N9O16 FW 857.8 [106362-32-7] |
|
|
| |
A potent HIV cell entry inhibitor. Acts by blocking chemokine-5 receptors (CCR5). |
|
|
| |
Polianova MT, Ruscetti FW, Pert CB et al. Peptides. 24(7): 1093-1098 (2003). |
|
|
| |
|
|
|
| P1763 |
Peptide YY, human |
1 mg |
$308.20 |
| |
C194H295N55O57 FW 4309.8 [118997-30-1] |
2 mg |
$523.30 |
| |
An appetite inhibiting protein secreted by the intestine. |
5 mg |
$924.70 |
| |
Butler MG, Bittel DC, Talebizadeh Z. J Ped Endocrinology. 17(9):1177-1184 (2002). |
|
|
| |
|
|
|
| P1762 |
Peptide YY, porcine |
1 mg |
$308.20 |
| |
C190H288N54O57 FW 4240.7 [81858-94-8] |
2 mg |
$523.30 |
| |
|
5 mg |
$924.70 |
| |
|
|
|
| P1768 |
Peptide YY(3-36), PYY, human |
0.5 mg |
$179.20 |
| |
C180H279N53O54 FW 4049.55 |
1 mg |
$304.60 |
| |
|
2.5 mg |
$537.60 |
| |
|
|
|
| |
|
|
|
| P1755 |
Pentoxifylline |
10 g |
$34.50 |
| |
C13H18N4O3 FW 278.31 [6493-05-6] |
50 g |
$129.20 |
| |
A vasodilator that has potential as radiation sensitizer. It is capable of |
100 g |
$206.60 |
| |
stimulating drug induced apoptosis in leukemic cells. |
|
|
| |
Johnson FE, Harrison BR, McKirgan LW et al. Int J Oncol. 13:801-5 (1998). |
|
|
| |
|
|
|
| P1761 |
Pepstatin |
5 mg |
$37.60 |
| |
C34H63N5O9 FW 685.89 [26305-03-3] |
25 mg |
$112.90 |
| |
An inhibitor of acid proteases isolated from streptomyces. It has been shown to |
100mg |
$376.30 |
| |
induce contractile effects on rat aorta rings. |
|
|
| |
Petrescu G, Costuleanu M, Slatineanu SM et al. Rev Med Chir Soc Med Nat Iasi. 106:741-5 (2002). |
|
|
| |
Guyene TT, Devaux C, Menard J et al. J Clin Endocrinol Metab. 43:1301-6 (1976). |
|
|
| |
|
|
|
| P1770 |
Perillyl Alcohol |
10 g |
$52.10 |
| |
C10H16O FW 152.23 [536-59-4] |
50 g |
$154.90 |
| |
A monoterpene derived from Lavender, that induces apoptosis in colon tumor cells. Inhibits |
|
|
| |
mammary cancer by inducing hepatocyte phase II enzymes, glutathione-S-transferase. |
|
|
| |
Reddy BS, Wang CX, Samaha H et al. Cancer Res. 57:420-425 (1997). |
|
|
| |
Gould MN. Environ Health Perspect. 105 (Suppl 4):977-979 (1997). |
|
|
| |
|
|
|
| P1869 |
Perindopril |
100mg |
$44.80 |
| |
C19H32N2O5 FW 368.47 [82834-16-0] |
250mg |
$89.60 |
| |
A potent angiotensin converting enzyme inhibitor used for antihypertensive |
1 g |
$263.20 |
| |
therapy. |
|
|
| |
Yamamoto Y, Oiwa K, Hayashi M, Ohara T, Muranishi M. Hypertens Res. 28:571-8 (2005). |
|
|
| |
Ajayi AA, Lees KR, Reid JL. Eur J Clin Pharmacol. 30: 177-82 (1986). |
|
|
| |
|
|
|
| P2445 |
PGLa |
1 mg |
$233.00 |
| |
C88H162N26O22S FW 1968.5 [102068-15-5] |
|
|
| |
An antimicrobial peptide isolated from frog skin, which exerts its activity by permeabilizing |
|
|
| |
bacterial membranes. |
|
|
| |
da Silva A Jr, Teschke O. Biochim Biophys Acta. 1643:95-103 (2003). |
|
|
| |
Wieprecht T, Apostolov O, Beyermann M et al. Biochemistry. 39:442-52 (2000). |
|
|
| |
|
|
|
| P2303 |
Phallacidin |
1 mg |
$232.10 |
| |
C37H50N8O13S FW 846.91 [26645-35-2] |
5 mg |
$934.50 |
| |
A actin filament stabilizer isolated from Amanita phalloides. It differs from |
|
|
| |
Phalloidin in that it contains a carboxy group for coupling reactions. |
|
|
| |
Papakonstanti EA, Stournaras C. Mol Biol Cell. 15:1273-86 (2004). |
|
|
| |
Sampson K, Pickett-Heaps JD. Protoplasma. 217:166-76 (2001). |
|
|
| |
|
|
|
| P2304 |
Phalloidin |
1 mg |
$163.10 |
| |
C35H48N8O11S FW 788.87 [14766-45-4] |
5 mg |
$689.90 |
| |
An actin filament stabilizer isolated from Amanita phalloides. |
|
|
| |
Dubin M, Maurice M, Feldmann G et al. Gastroenterology. 75:450-5 (1978). |
|
|
| |
Thamilselvan V, Basson MD. Gastroenterology. 126:8-18 (2004). |
|
|
| |
|
|
|
| |
|
|
|
| P2400 |
Phenethyl caffeate |
50 mg |
$51.40 |
| |
Caffeic acid phenethyl ester, CAPE |
100mg |
$81.30 |
| |
C17H16O4 FW 283.31 [104594-70-9] |
500mg |
$266.90 |
| |
Active ingredient of honeybee hive products, propolis. Cytotoxic agent against |
|
|
| |
cancer cell lines. Inhibitor of ornithine decarboxylase and protein tyrosine kinase. |
|
|
| |
Grunberger D, Banerjee R, Eisinger K et al. Experientia 44:230-232 (1988). |
|
|
| |
Rao CV, Desai D, Kaul B, Amin S et al. Chem. Biol. Interactions 84:277-290 (1992). |
|
|
| |
|
|
|
| P2410 |
Phenethyl dimethyl caffeate |
50 mg |
$47.00 |
| |
C19H20O4 FW 312.37 M.P. 97-980C [14551-14-0] |
100mg |
$68.40 |
| |
Inhibitor of ornithine decarboxylase and protein tyrosine kinase. |
500mg |
$224.30 |
| |
Rao CV, Desai D, Kaul B et al. Chem. Biol. Interactions 84:277-290 (1992). |
|
|
| |
|
|
|
| P2502 |
Phenethyl glucosinolate potassium salt, 97% |
5 mg |
$131.50 |
| |
C15H19NO9S2K FW 460.55 [499-30-9] |
10 mg |
$239.90 |
| |
One of the numerous glucosinolates widely distributed in cruciferus vegetables. |
100mg |
$1,558.30 |
| |
Synthetic potassium salt of gluconasturtiin. |
|
|
| |
|
|
|
| P2508 |
Phenethyl isothiocyanate, 98% |
5 g |
$51.60 |
| |
2-Isothiocyanatoethylbenzene |
10 g |
$94.80 |
| |
C9H9NS FW 163.24, b.p.113oC/1mm [2257-09-2] d. 1.094 |
50 g |
$421.90 |
| |
Inhibitor of NNK-induced lung tumorigenesis. |
|
|
| |
Jiao D, Smith TJ, Yang CS et al. Carcinogenesis. 11:2143-2147 (1997). |
|
|
| |
|
|
|
| |
Phenethyl isothiocyanate N-acetyl-L-cysteine conjugate |
|
|
| |
See N-acetyl-S-(N'-phenethylthiocarbamoyl)-L-cysteine |
|
|
| |
|
|
|
| P2817 |
Phentolamine Hydrochloride |
50 mg |
$34.50 |
| |
C17H19N3O.HCl FW 317.81 [73-05-2] |
100mg |
$51.60 |
| |
a-Adrenergic blocker. |
500mg |
$206.60 |
| |
Meier R et al. Proc Soc Exp Biol Med 71:70 (1949). |
|
|
| |
|
|
|
| |
|
|
|
| P2818 |
Phentolamine mesylate |
50 mg |
$34.50 |
| |
C17H19N3O.CH3SO3H FW 377.46 [65-28-1] |
100mg |
$51.60 |
| |
a-Adrenergic blocker. Used to treat male erectile dysfunction. |
500mg |
$206.60 |
| |
McMahon CG. Int J Impot Res. 8:233-6 (1996). |
|
|
| |
|
|
|
| |
|
|
|
| P2919 |
L-Phenylalaninol |
1 g |
$31.80 |
| |
(S)-(-)-2-Amino-3-phenyl-1-propanol |
5 g |
$135.30 |
| |
C9H13NO FW 151.21 [3182-95-4] |
25 g |
$482.90 |
| |
It inhibits ulcer formaiton by the reduction of gastric acid secretion. |
|
|
| |
Hashizume H, Miyamae T, Morikawa T, Hagiwara M. Chem Pharm Bull (Tokyo). 40:3113-4 (1992). |
|
|
| |
|
|
|
| P2810 |
Phenylbutazone |
25 g |
$26.00 |
| |
C19H20N2O2 FW 308.37 [50-33-9] |
100 g |
$68.90 |
| |
A non steroidal anti-inflammatory drug (NSAID). Several lines of evidence suggest that NSAID |
|
|
| |
may be effective in preventing colorectal cancer. Phenylbutazone lowers the incidence of pancreatic |
|
|
| |
carcinoma in experimental animals treated with N-nitrosobis (2-oxopropyl) amine. |
|
|
| |
Hixson LJ, Alberts DS, Krutzsch et al. Cancer Epidemiol Biomarkers Prev. 3:433-8 (1994). |
|
|
| |
Takahashi M, Furukawa F, Toyoda K et al. Carcinogenesis. 11:393-5 (1990). |
|
|
| |
|
|
|
| P2510 |
4-Phenylbutyl isothiocyanate |
1 g |
$47.00 |
| |
C11H13NS FW 191.308 [61499-10-3] d. 1.006 |
5 g |
$180.20 |
| |
A synthetic phenyl alkyl isothiocyanate that has been found to induce Phase II |
10 g |
$335.80 |
| |
detoxifying enzymes. It also inhibits chemically induced carcinogenesis. |
|
|
| |
Morse M A, Eklind K I, Amin SG et al. Carcinogenesis. 10:1757-1759 (1989). |
|
|
| |
Wilkinson JT, Morse .A et al. Carcinogenesis 16:1011-1015 (1995). |
|
|
| |
|
|
|
| P2815 |
Phenylbutyrate |
1 g |
$34.50 |
| |
4-Phenylbutyric acid sodium salt |
5 g |
$112.10 |
| |
C10H11O2 FW 186.18 [1716-12-7] |
25 g |
$447.60 |
| |
An aromatic fatty acid that induces cytostasis, differentiation and apoptosis in primary myeloid |
|
|
| |
leukemic cells, human prostate cancer cell lines and human colon carcinoma cells. It also |
|
|
| |
has chemopreventive effects against chemically induced colon carcinogenesis in experimental animals. |
|
|
| |
Digiuseppe JA, Weng LJ, Yu KH et al. Leukemia. 13:1243-53 (1999). |
|
|
| |
Ng AY, BAles W, Veltri RW. Anls Quant Cyto Histol. 22:45-54 (2000). |
|
|
| |
Huang Y, Horvath CM, Waxman S. Cancer Res. 60:3200-6 (2000). |
|
|
| |
Wargovich MJ, Jimenez A, Mc kee K et al. Carcinogenesis. 21:1149-55 (2000). |
|
|
| |
|
|
|
| P1917 |
Phenylethyl 3-methylcaffeate |
50 mg |
$49.50 |
| |
C18H18O4 FW 298.33 [71835-85-3] |
100mg |
$77.80 |
| |
It has chemopreventive property against chemically induced colon |
500mg |
$254.40 |
| |
carcinogenesis,and enhances apoptosis in azoxymethane induced colon tumors. |
|
|
| |
Rao CV, Desai O, Rivenson A et al. Cancer Res. 55: 2310-5 1 (1995). |
|
|
| |
Samaha HS, Kelloff G J, Steele V et al. Cancer Res. 57:1301-5 (1997). |
|
|
| |
|
|
|
| P2918 |
Phenylethyl 4-methylcaffeate |
25 mg |
$51.10 |
| |
C18H18O4 FW 298.33 |
50 mg |
$80.60 |
| |
|
250mg |
$268.60 |
| |
|
|
|
| P2819 |
6-Phenyl-hexa-3,5-dien-2-one |
5 mg |
$160.60 |
| |
C12H12O FW 172.22 [4173-44-8] |
10 mg |
$275.40 |
| |
A minor component of kava kava extract. |
|
|
| |
|
|
|
| P2922 |
Phenylhexyl isothiocyanate |
100mg |
$82.00 |
| |
C13H17NS FW 219.35 [133920-06-6] |
250mg |
$164.00 |
| |
Chemopreventive agent in mouse lung. Found to enhance colon and esophageal |
500mg |
$246.00 |
| |
tumorigenesis in the rat. |
|
|
| |
Morse MA, Eklind KI, Hecht SS. et al. Cancer Res. 51:1846-50 (1991). |
|
|
| |
Rao CV, Rivenson A, Simi B et al. Cancer Res. 55:4311-8 (1995). |
|
|
| |
Stoner GD, Siglin JC, Morse MA et al. Carcinogenesis. 16:2473-6 (1995). |
|
|
| |
|
|
|
| P2513 |
Phenyl isothiocyanate |
50 g |
$22.20 |
| |
Phenyl mustard oil, PITC |
100 g |
$36.20 |
| |
C7H5NS FW 135.19 b.p. 2210C [103-72-0] d. 1.130 |
|
|
| |
Inhibitor of NNK-induced lung tumorigenesis. |
|
|
| |
Jiao D, Smith TJ, Yang CS et al. Carcinogenesis. 11:2143-2147 (1997). |
|
|
| |
|
|
|
| P2515 |
3-Phenylpropyl isothiocyanate |
5 g |
$139.30 |
| |
C10H11NS FW 177.27 [2627-27-2] d. 1.070 |
10 g |
$251.90 |
| |
Synthetic phenyl isothiocyanate that has been found to induce Phase II detoxifying |
|
|
| |
enzymes. It also inhibits chemically induced carcinogenesis. |
|
|
| |
Morse M A, Eklind K I, Amin SG et al. Carcinogenesis. 10:1757-1759 (1989). |
|
|
| |
Benson AM, Barretto PB. Cancer Res. 45:4219-4223 (1985). |
|
|
| |
Sparnins VL, Chuan J, Wattenberg LW. Cancer Res. 42:1205-1207 (1982). |
|
|
| |
Morse MA, Amin SG, Hecht SS, Chung FL. Cancer Res 49:2894-2897 (1989). |
|
|
| |
Wilkinson JT, Mors MA, Kresty LA, Stoner GD. Carcinogenesis. 16:1011-1015 (1995). |
|
|
| |
|
|
|
| P2816 |
S-(N-3-Phenylpropylthiocarbamoyl)-L-cysteine |
100mg |
$42.00 |
| |
C13H18N2O2S2 FW 298.42 m.p. 202-2080C [137915-13-0] |
500mg |
$124.80 |
| |
|
1 g |
$220.80 |
| |
Cysteine conjugate of phenylpropyl isothiocyanate. |
|
|
| |
|
|
|
| P2832 |
PHI, porcine |
1 mg |
$281.00 |
| |
C136H216N36O40 FW 2995.4 |
|
|
| |
Peptide hisitidine isoleucine has been shown to induce an anorexigenic response in rats. |
|
|
| |
It also plays a critical role in the generation of circadian oscillations. |
|
|
| |
|
|
|
| P2833 |
PHI, rat |
0.5 mg |
$121.90 |
| |
C136H216N36O41 FW 3011.45 |
1 mg |
$207.90 |
| |
|
2.5 mg |
$365.60 |
| |
|
|
|
| P2845 |
Phleomycin |
5 mg |
$50.20 |
| |
C51H75N17O21S2 FW 1326.38 [11006-33-0] |
25 mg |
$175.60 |
| |
A glycopeptide antibiotic from the bleomycin family. It catalyzes double- |
100mg |
$526.80 |
| |
strand breaks in DNA. |
|
|
| |
He CH, Masson JY, Ramotar D. Can J Microbiol. 42:1263-6 (1996). |
|
|
| |
Nakada D, Shimomura T, Matsumoto K et al. Nucleic Acids Res. 31:1715-24 (2003). |
|
|
| |
|
|
|
| P2856 |
Phorbol-12,13-dibutyrate |
1 mg |
$75.30 |
| |
C30H46O8 FW 504.61 [37558-16-0] |
5 mg |
$177.50 |
| |
PKC activator. |
|
|
| |
Less potent than TPA. |
|
|
| |
|
|
|
| P2857 |
Phorbol-12-myristate-13-acetate |
1 mg |
$46.70 |
| |
|
5 mg |
$139.70 |
| |
C36H56O8 FW 616.83 [16561-29-8] |
|
|
| |
A very potent promoter of carcinogenesis. Binds to and activates protein kinase C. |
|
|
| |
Blumberg PM. Crit. Rev. Toxicol. 8:153-197 (1980). |
|
|
| |
|
|
|
| P2858 |
4-a-Phorbol-12-myristate-13-acetate |
1 mg |
$93.50 |
| |
C36H56O8 FW 616.83 [63597-44-4] |
5 mg |
$372.50 |
| |
An inactive negative control for TPA. |
|
|
| |
Van Duuren BL, Tseng SS, Segal A et al. Cancer Res. 39:2644-2646 (1979). |
|
|
| |
|
|
|
| |
|
|
|
| P2859 |
Phosphate Acceptor Peptide |
1 mg |
$57.30 |
| |
C41H74N16O11 FW 967.15 |
2 mg |
$96.80 |
| |
|
5 mg |
$172.00 |
| |
|
|
|
| P2992 |
Phyllolitorin |
0.5 mg |
$43.00 |
| |
C49H69N11O11S1 FW 1020.24 |
1 mg |
$73.50 |
| |
|
2.5 mg |
$129.00 |
| |
|
|
|
| P2993 |
Phyllomedusin |
1 mg |
$78.80 |
| |
C52H82N16O13S1 FW 1171.41 |
2 mg |
$134.40 |
| |
|
5 mg |
$236.50 |
| |
|
|
|
| P2994 |
Physalaemin |
1 mg |
$43.00 |
| |
C56H84N14O16S1 FW 1265.48 |
2 mg |
$73.50 |
| |
|
5 mg |
$129.00 |
| |
|
|
|
| P2995 |
Physcion |
10 mg |
$75.30 |
| |
C16H12O5 FW 284.26 [521-61-9] |
25 mg |
$123.00 |
| |
A anthraquinone isolated from Rheum emodi with antifungal and |
100mg |
$376.30 |
| |
antitumor activity. |
|
|
| |
Agarwal SK, Singh SS, Verma S et al. J Ethnopharmacol. 72:43-6 (2000). |
|
|
| |
Kuo YC, Sun CM, Ou JC et al. Life Sci. 61:2335-44 (1997). |
|
|
| |
|
|
|
| P2997 |
Phytic Acid, 40-50 wt% aqueous solution |
100 ml |
$56.40 |
| |
Inositol hexaphosphate |
500 ml |
$202.40 |
| |
C6H18O24P6 FW 660.04 [83-86-3] |
|
|
| |
A constituent of wheat bran shown to have antineoplastic action in colon |
|
|
| |
carcinogenesis. Inhibits cell proliferation and increases cell differentiation. |
|
|
| |
Sakamoto K, Venkatraman G, Shamsuddin AM. Carcinogenesis 14:1815-1819 (1993). |
|
|
| |
|
|
|
| |
Piceid (See polydatin) |
|
|
| |
|
|
|
| P3313 |
Pidotimod |
1 g |
$75.30 |
| |
C9H12N2O4S FW 244.27 [121808-62-6] |
5 g |
$276.00 |
| |
A biological response modifier. It inhibits apoptosis induced by several agents, |
10 g |
$482.90 |
| |
including genistein. |
|
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| |
Migliorati G, Nicoletti I, Riccardi C. Arzneimittelforschung. 44:1421-4 (1994). |
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| |
Gourgiotis D, Padaopoulos NG, Bossios A et al. J Asthma. 41:285-7 (2004). |
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| |
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| |
Pimaricin (See natamycin) |
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| |
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| P6954 |
Pioglitazone Hydrochloride |
100mg |
$82.90 |
| |
C19H20N2O3S.HCl FW 392.91 [112529-15-4] |
500mg |
$276.00 |
| |
Orally active antihyperglycemic agent effective as treatment of non-insulin- |
1 g |
$496.80 |
| |
dependent diabetes mellitus. It inhibits cholesterol absorption and shows |
|
|
| |
anti-inflammatory and anti-arterioscleortic effects. |
|
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| |
Ikeda H, Taketomi S, Sugiyama Y et al. Arzneimittel-Forschung 40:156-162 (1990). |
|
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| |
Colca JR, Dailey CF, Palazuk BJ et al. Diabetes 40:1669-1674 (1991). |
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| |
Ishibashi M, Egashira K, Hiasa K et al. Hypertension. 40:687-693 (2002). |
|
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| |
|
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|
| P3462 |
Piperacillin |
1 g |
$41.40 |
| |
C23H27N5O7S FW 517.56 [61477-96-1] |
5 g |
$172.50 |
| |
A semisynthetic penicillin with broad spectrum of antimicrobial activity. |
10 g |
$303.60 |
| |
Jones RN, Thornsberry C, Barry AL et al. J Antibiot (Tokyo). 30:1107-14 (1977). |
|
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| |
|
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|
| P3463 |
Piperacillin sodium |
1 g |
$48.40 |
| |
C23H26N5NaO7S FW 539.54 [59703-84-3] |
5 g |
$193.20 |
| |
|
10 g |
$345.00 |
| |
|
|
|
| P3465 |
Piperine |
1 g |
$31.40 |
| |
C17H19NO3 FW 285.34 [94-62-2] |
5 g |
$131.70 |
| |
An alkaloid from black pepper. It shows chemopreventive, cytotoxic, anti-inflammatory, |
|
|
| |
and antioxidant effects. It is suggested that piperine exerts its chemopreventive effect by modulating |
|
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| |
lipid peroxidation and augmenting antioxidant defense system. |
|
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| |
Sunila ES, Kuttan G. J Ethnopharmacol. 90:339-46 (2004). |
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| |
Selvendiran K, Senthilnathan P, Magesh V et al. Phytomedicine. 11:85-9 (2004). |
|
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| |
Mittal R, Gupta RL. Methods Find Exp Clin Pharmacol. 22:271-4 (2000). |
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| |
|
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|
| P3568 |
Pirarubicin |
5 mg |
$112.00 |
| |
C32H37NO12 FW 627.64 [72496-41-4] |
10 mg |
$196.00 |
| |
An analogue of the anthracycline anti-neoplastic doxorubicin. Pirarubicin |
25 mg |
$414.40 |
| |
intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication. |
|
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| |
KudoKazuko.Journalofclinicaloncology:officialjournalofthe AmericanSocietyofClinicalOncology(2007),25(34),5442-7. |
|
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| |
|
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|
| P3269 |
Piroxicam |
1 g |
$35.30 |
| |
C14H11N3O4S FW 317.32 m.p. 198-2000C [36322-90-4] |
5 g |
$132.00 |
| |
A non-steroidal anti-inflammatory agent proven to be an effective |
10 g |
$234.90 |
| |
chemopreventive in colon and urinary bladder carcinogenesis models. |
|
|
| |
Reddy BS. Prev.Med. 25:48-50 (1996). |
|
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| |
Okajima E, Ozono S, Endo T et al. Jpn. J. Cancer Res. 88:543-552 (1997). |
|
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| |
|
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|
| P3576 |
Pitavastatin |
10 mg |
$44.80 |
| |
C50H46CaF2N2O8 FW 880.98 [147526-32-7] |
25 mg |
$84.00 |
| |
Like the other statins, it is an inhibitor of HMG-CoA reductase, the enzyme that |
100mg |
$224.00 |
| |
catalyses the first step of cholesterol synthesis. |
|
|
| |
Yamazaki, H., Journal of Atherosclerosis and Thrombosis (2006), 13(6), 295-307. |
|
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| |
SALES RESTRICTION:
This product is offered for R&D use in accordance with 35 USC 271(e)+A13(1) in the United States and similar laws and regulations in other countries only. It is not available in some countries where such sales are prohibited; not available to some institutions or for other uses. |
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| |
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|
| P3597 |
Pizotyline malate |
1 g |
$56.40 |
| |
Pizotifen malate |
5 g |
$207.00 |
| |
C19H21NS.C4H6O5 FW 429.54 [5189-11-7] |
10 g |
$351.20 |
| |
A serotonin receptor antagonist used as an antimigraine. |
|
|
| |
It has shown venoconstrictor activity in vivo. |
|
|
| |
Muller-Schweinitzer E. J Cardiovasc Pharmacol. 8:805-10 (1986). |
|
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| |
Cleland PG, Barnes D, Elrington GM et al. Eur Neurol. 38:31-8 (1997). |
|
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| |
|
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|
| P4008 |
PKC412 |
1 mg |
$140.00 |
| |
Midostaurin; 4'-N-Benzoyl staurosporine |
5 mg |
$560.00 |
| |
C35H30N4O4 FW 570.64 [120685-11-2] |
|
|
| |
Tyrosine kinase inhibitor being studied in the treatment of cancer. Cell permeable |
|
|
| |
inhibitor of protein kinases, including protein kinase C. |
|
|
| |
Moellgard, L. Cancer Chemotherapy and Pharmacology (2008), 62(3), 439-448. |
|
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| |
|
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|
| P4403 |
Plasminogen Activator Inhibitor 1 (PAI-1) |
0.5 mg |
$35.80 |
| |
C27H47N9O9S FW 673.79 |
1 mg |
$60.90 |
| |
|
2.5 mg |
$107.50 |
| |
|
|
|
| P4560 |
PLP (139-151) |
1 mg |
$107.50 |
| |
Proteolipid protein |
5 mg |
$412.20 |
| |
C72H104N20O17 FW 1521.7 |
|
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| |
|
|
|
| P5712 |
Podophyllotoxin |
50 mg |
$27.00 |
| |
C22H22O8 FW 414.41 m.p. 114-1180C [518-28-5] |
100mg |
$44.90 |
| |
An antineoplastic agent that inhibits microtubule assembly. |
500mg |
$188.00 |
| |
Roach MC et al. J. Biol. Chem. 260:3015 (1985). |
|
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| |
|
|
|
| P5845 |
Polydatin |
250mg |
$56.40 |
| |
Resveratrol 3-b-mono-D-glucoside, Piceid |
1 g |
$125.40 |
| |
C20H22O8 FW 390.38 [65914-17-2] |
|
|
| |
A natural product from Polygonum cuspidatum, found to posses prophylactic and therapeutic |
|
|
| |
effects. Polydatin has been shown to inhibit ICAM-1 expression in endothelial cells stimulated |
|
|
| |
by lipopolysaccharide. |
|
|
| |
Zhao KS, Jin C, Huang X et al. Clin Hemorheol Microcirc. 29:211-7 (2003). |
|
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| |
Shu SY, Wang XY, Ling ZY et al. Chin J Traumatol. 7:239-43 (2004). |
|
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| |
|
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|
| P5878 |
Potassium canrenoate |
1 g |
$27.70 |
| |
Canrenoic acid potassium salt |
5 g |
$69.00 |
| |
C22H29KO4 FW 396.56 [2181-04-6] |
25 g |
$310.50 |
| |
An aldosterone antagonist, antiarrhythmic and diuretic drug. It has been |
|
|
| |
found to produce genotoxic effects in cultured rat and human cells. |
|
|
| |
Martelli A, Mattioli F, Carrozzino R et al. Mutagenesis.14:463-72 (1999). |
|
|
| |
Marchetti G, Vitolo E, Di Francesco GF et al. Arch Int Pharmacodyn Ther. 266:250-63 (1983). |
|
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| |
|
|
|
| P5885 |
Povidone iodine |
50 g |
$34.50 |
| |
[25655-41-8] |
100 g |
$55.20 |
| |
A topical antiseptic. |
|
|
| |
Flynn J. Br J Community Nurs. 8:S36-42 (2003). |
|
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| |
|
|
|
| P6901 |
Pramipexole |
10 mg |
$50.40 |
| |
C10H17N3S FW 211.33 [104632-26-0] |
25 mg |
$84.00 |
| |
Is a medication for treating ParkinsonŐs disease and restless leg syndrome. |
100mg |
$224.00 |
| |
A non-ergoline dopamine agonist. |
|
|
| |
Arbouw, M. E. L. European Journal of Clinical Pharmacology (2008), 64(10), 1021-1026. |
|
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| |
|
|
|
| P6802 |
Pranoprofen |
100mg |
$50.40 |
| |
C15H13NO3 FW 255.27 [52549-17-4] |
250mg |
$89.60 |
| |
A non-steroidal antiinflammatory drug inhibits platelet aggregation. |
1 g |
$224.00 |
| |
Goto, K. Mikashima, H., Terasawa, M.et al J. Pharm Soc. Japan 97:1211-1215 (1977). |
|
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| |
|
|
|
| P6800 |
Pravastatin Lactone |
10 mg |
$53.20 |
| |
C23H34O6 FW 406.51 |
50 mg |
$159.50 |
| |
Pravastatin lactone is an antihyper- lipoproteinemic. |
100mg |
$280.90 |
| |
O'Neil, M. (ed.) The Merck Index, 13th ed. Merck & Co. Inc. Whitehouse Station, NJ 2001. |
|
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| |
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| |
|
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|
| P6801 |
Pravastatin Sodium |
10 mg |
$36.10 |
| |
C23H35NaO7 FW 446.51 |
50 mg |
$147.10 |
| |
Biologically active metabolite of mevastatin, HMG-CoA reductase inhibitor. |
100mg |
$277.50 |
|
Raasch RH. DICP. 25:388-394 (1991). |
|
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| |
Egashira K, Hirooka Y, Kai H et al. Circulation. 89:2519-24 (1994). |
|
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| |
|
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|
| P7103 |
Praziquantel |
1 g |
$22.80 |
| |
C19H24N2O2 FW 312.41 [55268-74-1] |
5 g |
$53.20 |
| |
An anthelmintic that is highly effective against all Schistosoma species. |
25 g |
$189.80 |
| |
Pearson RD, Guerrant RL. Ann. Internal Med. 99:195-198 (1983). |
|
|
| |
|
|
|
| P6818 |
Prednisolone |
1 g |
$21.70 |
| |
C21H28O5 FW 360.4 [50-24-8] |
5 g |
$82.50 |
| |
A glucocorticoid with anti-inflammatory and immuno-suppressive activity in |
10 g |
$158.40 |
| |
rabbits. It induces apoptosis in colon cancer cell lines and eosinophils. Research results |
|
|
| |
show that predinisolone in combination with TNP-470 may be a very effective drug |
|
|
| |
for angiosarcoma treatment. |
|
|
| |
Meng RD, El-Deiry WS. Exp Cell Res. 262: 154-169 (2001). |
|
|
| |
Fan GK, Itoh T, Imanaka Met al. J Allergy Clin Immunol.106: 551-8 (2000). |
|
|
| |
Ma G, Masuzawa M, Hamada Y et al. J Dermatol Scie. 24:126-33 (2000). |
|
|
| |
|
|
|
| P7012 |
Prednisolone sodium phosphate |
5 g |
$127.90 |
| |
C21H27Na2O8P FW 484.39 [125-02-0] |
10 g |
$213.00 |
| |
Water soluble form of prednisolone. |
25 g |
$409.90 |
| |
|
|
|
| |
|
|
|
| P7020 |
Prednisone |
1 g |
$20.70 |
| |
C21H26O5 FW 358.43 [53-03-2] |
5 g |
$75.90 |
| |
An anti-inflammatory adrenocortical steroid used to treat Crohn's disease. It |
25 g |
$276.00 |
| |
reduces intestinal permeability, mucosal TNF-a production and levels of NF-kB expression. |
|
|
| |
Wild GE, Waschke KA, Bitton A, Thomson AB. Aliment Pharmacol Ther. 18:309-17 (2003). |
|
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| |
|
|
|
| P7021 |
Prednisone Acetate |
1 g |
$24.90 |
| |
C23H28O6 FW 400.46 [125-10-0] |
5 g |
$82.90 |
| |
|
25 g |
$289.90 |
| |
|
|
|
| |
|
|
|
| P7023 |
Pregnenolone |
5 g |
$27.70 |
| |
5-Pregnen-3b-ol-20-one |
25 g |
$75.90 |
| |
C21H32O2 FW 316.48 [145-13-1] |
100 g |
$289.90 |
| |
An endogenous neurosteroid inhibits GABA-gated chloride currents by enhancing receptor |
|
|
| |
desensitization. It modulates NMDA receptors resulting in delayed apoptotic retinal cell death. |
|
|
| |
It stimulates prostate LNCaP cell proliferation through binding to the mutated androgen receptor. |
|
|
| |
Shen W, Mennerick S, Covey DF, Zorumski CF. J Neurosci. 20:3571-9 (2000). |
|
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| |
Cascio C, Guarneri R, Russo D et al. J Neurochem. 74:2380-91(2000). |
|
|
| |
Grigoryev DN, Long BJ, Njar VC, Brodie AH. J Steroid Biochem Mol Biol. 75:1-10 (2000). |
|
|
| |
|
|
|
| P7022 |
Pressinoic Acid |
1 mg |
$35.80 |
| |
C33H42N8O10S2 FW 774.08 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| P7033 |
Primaquine phosphate |
5 g |
$34.50 |
| |
C15H21N3O.2H3PO4 FW 455.29 [63-45-6] |
10 g |
$55.20 |
| |
An antimalarial drug with genotoxicity (Ames test) and |
50 g |
$186.40 |
| |
cardiotoxicity (inhibitor of cardiac Na+ current). |
|
|
| |
Chatterjee T, Muhkopadhyay A, Khan KA, Giri AK. Mutagenesis. 13:619-24 (1998). |
|
|
| |
Orta-Salazar G, Bouchard RA, Morales-Salgado F et al. Br J Pharmacol. 135 :751-63 (2002). |
|
|
| |
|
|
|
| P7034 |
Prion Peptide (106-126), human |
1 mg |
$86.00 |
| |
C80H138N26O24S2 FW 1912.28 [148439-49-0] |
2 mg |
$150.50 |
| |
|
5 mg |
$218.60 |
| |
|
|
|
| P6858 |
Procarbazine Hydrochloride |
100mg |
$43.10 |
| |
C12H19N3O.HCl FW 257.77 [366-70-1] |
500mg |
$112.10 |
| |
Antineoplastic agent. |
1 g |
$189.40 |
| |
Newell D, Gescher A, Harland S et al. Cancer Chemother Pharmacol. 19:91-102 (1987). |
|
|
| |
|
|
|
| P7056 |
Procaterol Hydrochloride |
10 mg |
$84.00 |
| |
C16H22N2O3.HCl FW 326.82 [59828-07-8] |
25 mg |
$179.20 |
| |
A vasodialator used for the long term treatment of asthma. It is also a specific |
100mg |
$616.00 |
| |
and very potent B2 antagonist. |
|
|
| |
Yu, T.-W. Drug Development and Industrial Pharmacy (2006), 32(6), 651-660. |
|
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| |
|
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| |
|
|
|
| P6859 |
Proctolin |
1 mg |
$35.80 |
| |
C30H48N8O8 FW 648.77 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| P6854 |
Progesterone |
5 g |
$18.10 |
| |
C21H30O2 FW 314.46 [57-83-0] |
25 g |
$75.50 |
| |
A steroid hormone secreted by the corpus luteum. Maintains pregnancy, |
100 g |
$295.50 |
| |
prevents ovulation. |
|
|
| |
Sivaraman L, Medina D. J Mammary Gland Biol Neoplasia. 7:77-92 (2002). |
|
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| |
|
|
|
| P6850 |
Prolactin-Releasing Peptide (1-31), human |
1 mg |
$322.60 |
| |
PrRP-31, human |
|
|
| |
C160H252N56O42S FW 3664.2 |
|
|
| |
|
|
|
| P6852 |
Propafenone Hydrochloride |
1 g |
$24.60 |
| |
C21H27NO3.HCl FW 377.91 [34183-22-7] |
5 g |
$73.90 |
| |
Antiarrhythmic agent that has little or no beta-blocking property. It appears to to inhibit Ca++ |
|
|
| |
inward current. |
|
|
| |
Muller-Peltzer H, Greger G, Neugebauer G, Hollmann M. Eur J Clin Pharmacol. 25:831-3 (1983). |
|
|
| |
Harder DR, Belardinelli L. Experientia. 36:1082-3 (1980). |
|
|
| |
|
|
|
| P6956 |
Prostaglandin E1 |
1 mg |
$91.20 |
| |
PGE1 |
5 mg |
$276.00 |
| |
C20H34O5 FW 354.48 [745-65-3] |
10 mg |
$407.10 |
| |
One of the primary prostaglandins, used as a vasodilator. |
|
|
| |
Weir EK, Reeves JT, Grover RF. Prostaglandins. 10:623-31 (1975). |
|
|
| |
|
|
|
| P6959 |
Prothionamide |
1 g |
$48.40 |
| |
C9H12N2S FW 180.27 [14222-60-7] |
5 g |
$69.00 |
| |
An antibacterial used against Mycobacterium tuberculosis. |
25 g |
$248.40 |
| |
Urbanczik R. Chemotherapy. 26:276-81 (1980). |
|
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| |
|
|
|
| P6857 |
Protocatechuic Acid |
25 g |
$44.40 |
| |
3,4-Dihydroxybenzoic acid |
50 g |
$80.60 |
| |
C7H6O4 FW 154.12 m.p. 200-2020C [99-50-3] |
100 g |
$128.90 |
| |
A phenolic acid antioxidant present in fruits, vegetables and nuts. |
|
|
| |
Found to be an efficacious chemopreventive agent in several |
|
|
| |
carcinogenesis models. |
|
|
| |
Tanaka T, Kojima T, Kawamori T, Mori H. Cancer. 75:1433-1439 (1995). |
|
|
| |
|
|
|
| P6957 |
Protopanaxadiol |
5 mg |
$121.50 |
| |
C30H52O4 FW 476.73 [7755-01-3] |
10 mg |
$212.60 |
| |
Same type saponins enhance axonal and dendritic formation activity. |
25 mg |
$417.50 |
| |
It was shown to possess characteristic effects on the proliferation of |
|
|
| |
human leukemia cells. |
|
|
| |
Popovich DG, Kitts DD. Arch Biochem Biophys. 406:1-8 (2002). |
|
|
| |
Tohda C, Matsumoto N, Zoo K, Meselhy MR, Komatsu K. Jpn J Pharmacol. 90:254-62 (2002). |
|
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| |
|
|
|
| P6958 |
Protopanaxatriol |
5 mg |
$121.50 |
| |
C30H52O4 FW 476.73 [34080-08-5] |
10 mg |
$212.60 |
| |
|
25 mg |
$417.50 |
| |
|
|
|
| |
|
|
|
| P7059 |
Proxymetacaine Hydrochloride |
100mg |
$35.00 |
| |
C16H26N2O3 FW 294.39 [499-67-2] |
250mg |
$75.00 |
| |
is a local anesthetic that is used to numb the surface of a body part. |
1 g |
$240.00 |
| |
Peyman G A; The British journal of ophthalmology (1994), 78(2), 138-41. |
|
|
| |
|
|
|
| P7082 |
Prulifloxacin |
25 mg |
$39.20 |
| |
C21H20FN3O6S FW 461.46 [123447-62-1] |
100 mg |
$100.80 |
| |
A quinoline carboxilic acid antibioterial prodrug with activities against a variety |
500 mg |
$336.00 |
| |
of Gram-positive and -negative bacteria. Shown to be an effective treatment for |
|
|
| |
urinary tract and respiratory tract infections. |
|
|
| |
Matera MG. Pulm Pharmacol Ther. 19 (Suppl 1): 20-9 (2006). |
|
|
| |
Prats G, Rossi V, Salvatori E, Mirelis B. Expert Rev Anti Infect Ther. 4:27-41 (2006). |
|
|
| |
|
|
|
| P7318 |
Pseudo ginsenoside F11 |
5 mg |
$129.10 |
| |
C48H82O19 FW 963.15 |
10 mg |
$220.20 |
| |
A componet of Panax quinquefolium L. |
25 mg |
$440.30 |
| |
Antagonized the memory dysfunction induced by scopolamine. |
|
|
| |
Li Z, Guo YY, Wu CF, Li X, Wang JH. J Pharm Pharmacol. 51:435-40 (1999). |
|
|
| |
|
|
|
| P7628 |
pTH-Related Protein (1-34) (human, rat) |
0.5 mg |
$161.30 |
| |
C180H287N57O48 FW 4017.65 [112540-82-6] |
1 mg |
$274.20 |
| |
|
2.5 mg |
$483.80 |
| |
|
|
|
| P8117 |
Puerarin, 99% |
5 mg |
$92.80 |
| |
C21H20O9 FW 416.38 [3681-99-0] |
10 mg |
$155.00 |
| |
A flavonoid derivative from the traditional oriental medicine, Ge-gen. |
25 mg |
$344.40 |
| |
Purarin has potential antioxidant activity and impairs CYP catalyzed |
|
|
| |
drug metabolism. It's metabolite calycosin has cytotoxic activity. |
|
|
| |
Guerra MC, Speroni E, Broccoli M et al. Life Sci. 67: 2997-3006 (2000). |
|
|
| |
Kim DH, Yu Ku, Bae EA, Han M. J. Biol Pharm Bull. 21: 628-30 (1998). |
|
|
| |
|
|
|
| P8118 |
Puerarin, 96% |
100mg |
$53.20 |
| |
C21H20O9 FW 416.38 [3681-99-0] |
500mg |
$113.90 |
| |
|
1 g |
$151.90 |
| |
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| P8168 |
Puromycin |
10 mg |
$24.30 |
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C22H29N7O5 FW 471.51 [53-79-2] |
25 mg |
$51.60 |
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Antibiotic substance produced by the soil actinomycete Streptomyces alboniger. |
100mg |
$175.60 |
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Inhibitor of chemical carcinogenesis |
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Bonano E, Ruzittu M, Carla EC et al. Eur J Histochem. 44:237-46 (2000). |
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Huang P, Sandoval A, Van Den Neste E, Keating M J, Plunkett W. Leukemia. 14:1405-13 (2000). |
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| P8167 |
Puromycin aminonucleoside |
25 mg |
$156.80 |
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Stylomycin aminonucleoside |
100 mg |
$483.80 |
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C12H18N6O3 FW 294.31 [58-60-6] |
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Puromycin derivative that has antibiotic and antineoplastic properties, can cause nephrosis. |
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Marshall CB, Pippin JW, Krofft RD, Shankland SJ Kidney Int. 70:1962-73 (2006). |
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Egashira Y, Nagaki S, Sanada H Int. J. Vitam. Nutr. Res. 76:28-33 (2006). |
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| P8169 |
Purpurin |
5 g |
$27.30 |
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C14H8O5 FW 256.21 m.p. 253-2560C [81-54-9] |
25 g |
$123.60 |
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A xanthine oxidase inhibitor, which inhibits azoxymethane-induced |
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aberrant crypt foci in the rat. |
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Wargovich MJ, Chen CD, Jimenez A et al. Cancer Epidemiol. Biomarkers Prev 5:355-360 (1996). |
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Sheu SY, Chiang HC. Anticancer Res. 17:3293-3297 (1997). |
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| P8270 |
Purvalanol A |
1 mg |
$92.30 |
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C19H25ClN6O FW 388.89 [212844-53-6] |
5 mg |
$359.60 |
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Arrests cell cycle progression and induces apoptosis by inhibition of cyclin-dependent kinases. |
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Has shown antiviral and anticancer activity in several studies. |
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Wang L, Deng L, Wu K et al. Mol Cell Biochem. 237:137-153 (2002). |
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Villerbu N, Gaben AM, Redeuilh H et al. Int J Cancer. 97:761-769 (2002). |
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Kudoh A, Daikoku T, Sugaya Y. J Virol. 78:105-115 (2004). |
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Gray NS, Wodicka L, Thunnissen et al. Science. 281:533-538 (1998). |
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| P9668 |
Pyrantel Pamoate |
5 g |
$19.70 |
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C11H14N2S.C23H16O6 FW 594.69 [22204-24-6] |
10 g |
$32.90 |
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An anthelmintic. |
50 g |
$106.50 |
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Desowitz RS, Bell T, Williams J, Cardines R, Tamarua M. Am J Trop Med Hyg. 19:775-8 (1970). |
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| P9671 |
Pyrazinamide |
10 g |
$27.70 |
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C5H5N3O FW 123.11 [98-96-4] |
25 g |
$44.20 |
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An antibacterial used in tuberculosis therapy often in combination with |
100 g |
$151.90 |
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rifampicin. |
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Zhang Y, Mitchison D. Int J Tuberc Lung Dis. 7:6-21 (2003). |
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| P6977 |
Pyr-Gly-Arg-pNA |
1 mg |
$53.80 |
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C19H26N8O6 FW 462.5 |
10 mg |
$179.20 |
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| P9869 |
Pyridoxine Hydrochloride |
25 g |
$22.40 |
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C8H12ClNO3 FW 205.64 [58-56-0] |
100 g |
$67.20 |
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A 4-methanol derivative of Vitamin B6. |
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| P9767 |
Pyriproxyfen |
5 g |
$43.90 |
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C20H19NO3 FW 321.37 [95737-68-1] |
25 g |
$125.40 |
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A larvicidal agent that mimics juvenile hormone. Shown to prevent maturation |
100 g |
$376.30 |
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of many species of insect. |
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Abo-Elghar GE, El-Shiekh AE, El-Sayed FM el al. Pest Manag Sci. 60:95-102 (2004). |
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Estrada JG, Mulla MS. J Am Mosquito Control Assoc. 2:314-320 (1986). |
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| P9768 |
Pyronaridine Tetraphosphate |
100mg |
$31.40 |
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C29H32ClN5O2.4H3PO4 FW 900.1 [76748-86-2] |
250mg |
$56.40 |
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A widely used antimalarial agent that has been found to significantly enhance the |
1 g |
$156.80 |
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antitumor activity of doxorubicin against multidrug-resistant cancers K562/A02 |
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and MCF-7/ADR. |
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Qi J, Wang S, Liu G et al. Biochem Bioph Res Comm. 319: 1124-1131 (2004). |
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Fu S, Bjorkman A, Wahlin B. Brit J Clin Pharmacol. 22: 93-96 (1986). |
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| P9770 |
Pyrrolostatin |
100 mg |
$83.00 |
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C15H21NO2 FW 247.33 [144314-68-1] |
1 mg |
$202.90 |
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Inhibits lipid peroxidation by scavenging free radicals. |
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Kato S, Shindo K, Kawai H et al. J Antibiotics. 46:892-899 (1993). |
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