| Q4370 |
Q-K-R-P-S-Q-R-S-K-Y-L |
1 mg |
$43.00 |
| |
C60H103N21O17 FW 1390.62 |
2 mg |
$71.70 |
| |
|
5 mg |
$129.00 |
| |
|
|
|
| Q8016 |
Quercetin Dihydrate |
25 g |
$33.30 |
| |
C15H10O7.2H2O FW 338.26 [6151-25-3] |
100 g |
$106.50 |
| |
A common flavonol, which inhibits lipoxygenase and ornithine decarboxylase induction. |
|
|
| |
Nakadate T, Aizu E, Yamamoto S, Kato R. Prostaglandins. 30:357-368 (1985). |
|
|
| |
|
|
|
| Q8019 |
Quetiapine Fumarate |
1 g |
$39.20 |
| |
2(C21H25N3O2S).C4H4O4 FW883.09[111974-72-2] |
5 g |
$140.00 |
| |
Is a psychotropic agent belonging to a chemical class, the dibenzothiapines. |
25 g |
$280.00 |
| |
Used in the treatement of dementia related psychosis. It is proposed that the |
|
|
| |
mechanism of action is through a dopamine type 2 and serotonin type 2 receptor. |
|
|
| |
Cortese, L. Journal of Clinical Psychopharmacology (2008), 28(1), 69-73. |
|
|
| |
|
|
|
| Q8133 |
Quinacrine Dihydrochloride Dihydrate |
10 g |
$32.00 |
| |
C23H30ClN3O.2HCl.2H2O FW 508.92 [6151-30-0] |
25 g |
$62.60 |
| |
A phospholipase A2 inhibitor. Showed synergistic inhibition of of prostate |
|
|
| |
cancer cells when used in combination with paclitaxel or lovastatin. |
|
|
| |
de Souza PL, Castillo M, Myers CE. Br J Cancer. 75:1593-600 (1997). |
|
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| |
|
|
|
| Q8134 |
Quinapril Hydrochloride |
100 mg |
$38.10 |
| |
C25H30N2O5.HCl FW 474.99 [82586-55-8] |
500 mg |
$113.90 |
| |
A firmly established and well tolerated angiotensin-converting enzyme inhibitor. |
1 g |
$182.20 |
| |
It attenuates the myocardial infarction induced rise in cardiac cytokine expression. |
|
|
| |
Clinical trials show that quinapril prevents restenosis after coronary stenting in |
|
|
| |
patients with angiotensin-coverting enzyme D allele. |
|
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| |
Warnica JW, Gilst WV, Baillot R, Johnstone D, Block P et al. Can J Cardiol. 18:1191-200 (2002). |
|
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| |
We GC, Siroi MG, QuR, Liu P, Roulea JL. Cardiovasc Drugs Ther. 16:29-36 (2002). |
|
|
| |
Culy CR, Jarvis B. Drugs. 62:339-85 (2002). |
|
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| |
|
|
|
| Q8135 |
Quinestrol |
100 mg |
$40.30 |
| |
Eston, Estrovis, Plestrovis |
250 mg |
$80.60 |
| |
C25H32O2 FW 364.52 [152-43-2] |
1 g |
$224.00 |
| |
It is used in estrogen replacement therapy. |
|
|
| |
Mann V, Huber C, Kogianni G, Collins F, Noble B Bone. 40:674-684 (2006). |
|
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| |
|
|
|
| R0105 |
Rabeprazole |
10 mg |
$106.60 |
| |
C18H21N3O3S FW 359.44 [117976-89-3] |
25 mg |
$188.20 |
| |
A proton pump/ATP-ase inhibitor. |
100 mg |
$602.10 |
| |
Furuta T, Shirai N, Sugimoto M et al. Pharmacogenomics. 5:181-202 (2004). |
|
|
| |
|
|
|
| R0109 |
Racecadotril |
100 mg |
$42.60 |
| |
C21H23NO4S FW 385.48 [81110-73-8] |
500 mg |
$121.50 |
| |
A potent enkephalinase inhibitor exhibits selective antisecretory activity. |
1 g |
$205.10 |
| |
Primi MP, Bueno L, Baumer P et al. Ali. Pharm Ther. 13 suppl6:3-7 (1999). |
|
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| |
|
|
|
| |
Racemethorphan (See Dextromethorphan Hydrobromide) |
|
|
| |
|
|
|
| R0110 |
Ractopamine |
1 g |
$50.40 |
| |
C18H23NO3 FW 301.38 [90274-24-1] |
5 g |
$201.60 |
| |
An adrenergic beta-Agonistsagonist with effects of increasing muscle mass and |
|
|
| |
decreasing body fat in rodents and lifestock. |
|
|
| |
Page et. al. Domest Anim Endocrinol. 26:23-31 (2004). |
|
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| |
|
|
|
| R0212 |
Radicicol |
1 mg |
$82.00 |
| |
Monorden |
5 mg |
$327.90 |
| |
C18H17ClO6 FW 364.78 [12772-54-5] |
|
|
| |
Macrolactone antibiotic from several fungi. It has antifungal activity. It is a tyrosine kinase |
|
|
| |
inhibitor, cell differentiation modulator, and has antiangiogenic activity. |
|
|
| |
Shimada et al. J. Antibiot. 48:824 (1995). |
|
|
| |
Pillay et al. Cell Growth Differ. 7:1487 (1996). |
|
|
| |
Oikawa et al. Eur J Pharmacol. 241:221 (1993). |
|
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| |
|
|
|
| R0243 |
Raloxifene Hydrochloride |
250 mg |
$73.90 |
| |
C28H27NO4S.HCl FW 510.05 [82640-04-8] |
500 mg |
$114.80 |
| |
A selective estrogen receptor modulator (SERM. It is effective for the prevention |
1 g |
$205.10 |
| |
of postmenopausal osteoporosis. It has been found to have caner chemopreventive |
|
|
| |
activity in laboratory animals and antiproliferative effecs in human breast cancer. |
|
|
| |
Anzano MA, Peer CW, Smith JM et al. J Natl Cancer Inst. 88:123-5 (1996). |
|
|
| |
Dowsett M, Bundred NJ, Decensi A et al. Cancer Epidemiol Biomarkers Prev. 10:961-6 (2001). |
|
|
| |
Seeman E. J Bone Miner Metab. 19:65-75 (2001). |
|
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| |
|
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|
| R0245 |
Raltitrexed |
10 mg |
$50.00 |
| |
|
25 mg |
$100.00 |
| |
An antimetabolite drug used in cancer chemotherapy which is an inhibitor |
100 mg |
$300.00 |
| |
of thymidylate synthase. |
|
|
| |
Liao, Zhi-Yong, Cancer Research (2005), 65(11), 4844-4851. |
|
|
| |
|
|
|
| R0249 |
Ramipril |
500 mg |
$69.00 |
| |
C23H32N2O5 FW 416.51 [87333-19-5] |
1 g |
$107.60 |
| |
An angiotensin-converting enzyme (ACE) inhibitor. |
5 g |
$414.00 |
| |
Ramipril is a prodrug of the active metabolite ramiprilat which is formed upon absorption. |
|
|
| |
Warner GT, Perry CM. Am J Cardiovasc Drugs. 3:113-6 (2003). |
|
|
| |
|
|
|
| R0349 |
Ramosetron |
10 mg |
$72.80 |
| |
C17H17N3O FW 279.34 [132036-88-5] |
25 mg |
$168.00 |
| |
Is a serotonin 5HT3 receptor antagonist for the treatment of nausea and vomiting |
100 mg |
$504.00 |
| |
in post-operative situations |
|
|
| |
Lee, H.-J. European Journal of Anaesthesiology (2008), 25(9), 756-762. |
|
|
| |
Matsueda, Kei. Scandinavian Journal of Gastroenterology (2008), 43(10), 1202-1211. |
|
|
| |
|
|
|
| R0250 |
Ranatensin |
1 mg |
$43.00 |
| |
C61H85N16O13S FW 1281.5 [29451-71-6] |
2 mg |
$71.70 |
| |
A frog skin peptide that interferes with nociception by action on the D2 receptor. |
5 mg |
$129.00 |
| |
Zhu HZ, Ji XQ, Wu SX et al. Chung Kuo Yao Li Hseuh Pao. 12(4):291-293 (1991). |
|
|
| |
|
|
|
| R0251 |
Ranatensin R |
1 mg |
$161.30 |
| |
C90H134N30O24S FW 2052.3 [70572-93-9] |
2 mg |
$274.20 |
| |
|
5 mg |
$483.80 |
| |
|
|
|
| R0253 |
Ranitidine hydrochloride |
1 g |
$24.60 |
| |
C13H23ClN4O3S FW 350.86 [66357-59-3] |
5 g |
$59.10 |
| |
A histamine H2-receptor antagonist used in the treatment of gastrointestinal |
|
|
| |
lesions due to excessive gastric acid secretion. |
|
|
| |
Grant SM, Langtry HD, Brogden RN. Drugs. 37:801-70 (1989). |
|
|
| |
Boyd EJ, Wilson JA, Wormsley KG. J Clin Gastroenterol. 5 Suppl 1:133-41 (1983). |
|
|
| |
|
|
|
| R0154 |
Ranolazine Dihydrochloride |
100 mg |
$110.40 |
| |
C24H33N3O4.2HCl FW 500.47 [95635-56-6] |
500 mg |
$414.00 |
| |
A novel metabolic modulator and membrane stabilizer. It is an antiischaemic and |
1 g |
$620.90 |
| |
antianginal agent. Shifts myocardial energy metabolism away from free fatty acids |
|
|
| |
and toward glucose as the substrate for production of adenosine triphosphate. |
|
|
| |
Schofielf RS, Hill JA. Expert Opin Investig Drugs. 11:117-23 (2002). |
|
|
| |
McCormack JG, Barr RL, Wolff AA et al. Circulation. 93:135-42 (1996). |
|
|
| |
Lodge JP, Lam FT, Perry SL et al. Transplantation. 50:755-9 (1990). |
|
|
| |
|
|
|
| R0161 |
Rapamycin |
1 mg |
$91.20 |
| |
C51H79NO13 FW 914.17 [53123-88-9] |
10 mg |
$239.60 |
| |
An antifungal antibiotic that has immunosuppressive activity. It blocks |
25 mg |
$524.60 |
| |
cytokine-mediated signal transduction pathways. |
|
|
| |
Singh K, Sun S. Vezina C. J Antibiot (Tokyo). 32:630-45 (1979). |
|
|
| |
Sehgal SN. Ther Drug Monit. 17:660-5 (1995). |
|
|
| |
|
|
|
| |
|
|
|
| R0272 |
Rasagiline |
25 mg |
$45.00 |
| |
C11H11N FW 157.21 [136236-51-6] |
100 mg |
$125.00 |
| |
Rasagiline is an irreversible inhibitor of monoamine oxidase used as a |
250 mg |
$200.00 |
| |
monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases. |
|
|
| |
It is selective for MAO type B over type A by a factor of fourteen. |
|
|
| |
Zhu, W. Journal of Neurochemistry (2008), 105(5), 1970-1978. |
|
|
| |
|
|
|
| R1806 |
Rebamipide |
1 g |
$34.50 |
| |
C19H15ClN2O4 FW 370.79 [90098-04-7] |
5 g |
$138.00 |
| |
An antiulcer agent that enhances mucosal resistance. It increases endogenous |
25 g |
$482.90 |
| |
prostaglandin in gastric mucosa, and also scavenges oxygen-derived free radicals |
|
|
| |
and inhibits their production. |
|
|
| |
Otsubo K. Morita S. Uchida M et al. Chem Pharm Bull. 39:2906-9 (1991). |
|
|
| |
Iinuma S. Naito Y. Yoshikawa T et al. Dig Dis Sci. 43:35S-39S (1998). |
|
|
| |
|
|
|
| R2711 |
Recombinant HCV-Core antigens |
100 µg |
$207.00 |
| |
|
1 mg |
$482.90 |
| |
|
|
|
| R2712 |
Recombinant HCV-NS3 antigens |
100 µg |
$207.00 |
| |
|
1 mg |
$482.90 |
| |
|
|
|
| R2713 |
Recombinant HCV-NS4 antigens |
100 µg |
$207.00 |
| |
|
1 mg |
$482.90 |
| |
|
|
|
| R2714 |
Recombinant HCV-NS5 antigens |
100 µg |
$207.00 |
| |
|
1 mg |
$482.90 |
| |
|
|
|
| R2811 |
Recombinant HIV-1 gp-41 |
100 µg |
$269.10 |
| |
|
1 mg |
$793.40 |
| |
|
|
|
| R2812 |
Recombinant HIV-1 gp-120 |
100 µg |
$269.10 |
| |
|
1 mg |
$793.40 |
| |
|
|
|
| R2815 |
Recombinant HIV-1"O"group consensus |
100 µg |
$345.00 |
| |
|
1 mg |
$965.90 |
| |
|
|
|
| R2816 |
Recombinant HIV-2 gp36 |
100 µg |
$269.10 |
| |
|
1 mg |
$793.40 |
| |
|
|
|
| R2710 |
Recombinant Multi-epitope Chimeric |
100 µg |
$207.00 |
| |
HCV antigen |
1 mg |
$482.90 |
| |
(Core, NS3, NS4, NS5) |
|
|
| |
|
|
|
| |
|
|
|
| R2810 |
Recombinant Multi-epitope Chimeric |
100 µg |
$407.10 |
| |
HIV antigen-1 |
1 mg |
$1,207.40 |
| |
(gp41, "O"IDR, gp36) |
|
|
| |
|
|
|
| |
|
|
|
| R3010 |
Recombinant Tp-chimeric protein |
100 µg |
$248.40 |
| |
(TpN15, TpN17, TpN44.5, TpN47) |
1 mg |
$724.40 |
| |
|
|
|
| |
|
|
|
| R3011 |
Recombinant TpN 15 protein |
100 µg |
$248.40 |
| |
|
1 mg |
$724.40 |
| |
|
|
|
| R3012 |
Recombinant TpN 17 protein |
100 µg |
$248.40 |
| |
|
1 mg |
$724.40 |
| |
|
|
|
| R3013 |
Recombinant TpN 44.50 protein |
100 µg |
$248.40 |
| |
|
1 mg |
$724.40 |
| |
|
|
|
| R3014 |
Recombinant TpN 47 protein |
100 µg |
$248.40 |
| |
|
1 mg |
$724.40 |
| |
|
|
|
| R1752 |
Renin Inhibitor Peptide |
5 mg |
$86.00 |
| |
C52H73N13O9 FW 1024.24 |
10 mg |
$145.20 |
| |
|
25 mg |
$258.00 |
| |
|
|
|
| R1774 |
Resiniferatoxin |
1 mg |
$86.10 |
| |
C37H40O9 FW 628.73 [57444-62-9] |
5 mg |
$408.10 |
| |
Natrual product isolated from Euphorbia poisonii. RTX is an irritant to skin |
10 mg |
$774.50 |
| |
and mucous membranes, but not a tumor promoter. It is an extremely potent |
|
|
| |
capsaicin analog that stimulates, with subsequent desensitization of specific subpopulations, |
|
|
| |
sensory receptors. |
|
|
| |
Hergenhahn M, Kusumoto S, Hecker EJ. Cancer Res. Clin.Oncol. 108:98-109 (1984). |
|
|
| |
Szallasi A, Blumber PM, Life Sci. 47:1399-1408 (1990). |
|
|
| |
Dray A, Biochem. Pharm. 44:611-615 (1992). |
|
|
| |
|
|
|
| R1775 |
Resiniferonol-9,13,14-orthophenyl acetate (ROPA) |
1 mg |
$80.60 |
| |
C28H32O6 FW 464.56 [57852-42-3] |
5 mg |
$323.00 |
| |
ROPA is a hydrolysis product of resiniferatoxin. |
10 mg |
$624.50 |
| |
ROPA retains its strong skin irritant property. |
|
|
| |
It is used to reconstitute either resiniferatoxin or tinyatoxin. |
|
|
| |
Jang M, Cai L, Udeani GO et al. Science, 275:218-220 (1997). |
|
|
| |
Carbo N, Costelli P, Baccino FM, Lopez-Soriano FJ. Biochem Ciophys Res Commun. 254:739-43 (1999). |
|
|
| |
Gautam SC, Xu YX, Dumaguin M et al. Bone Marrow Transplant. 25:639-45 (2000). |
|
|
| |
|
|
|
| R1776 |
Resveratrol |
100 mg |
$64.30 |
| |
C14H12O3 FW 228.24 [501-36-0] |
500 mg |
$270.10 |
| |
An antioxidant found in grapes, shown to have significant chemopreventive activity. |
|
|
| |
Jang M, Cai L, Udeani GO et al. Science. 275:218-220 (1997). |
|
|
| |
Carbo N, Costelli P, Baccino FM, Lopez-Soriano FJ. Biochem Ciophys Res Commun. 254:739-43 (1999). |
|
|
| |
Gautam SC, Xu YX, Dumaguin M et al. Bone Marrow Transplant. 25:639-45 (2000). |
|
|
| |
|
|
|
| R1777 |
9-cis-Retinoic acid |
1 mg |
$44.90 |
| |
C20H28O2 FW 300.44 m.p. 189-1900C [5300-03-8] |
5 mg |
$149.10 |
| |
A vitamin A analog that inhibits cell proliferation and induces cell differentiation. |
25 mg |
$596.10 |
| |
Kelloff GJ, Crowell JA, Hawk ET et al. J. Cell. Biochem Suppl. 26:54-71 (1996). |
|
|
| |
Zheng Y, Kramer PM, Olson G et al. Carcinogenesis. 18:2119-2125 (1997). |
|
|
| |
|
|
|
| R1779 |
13-cis-Retinoic acid |
100 mg |
$53.20 |
| |
C20H28O2 FW 300.44 m.p. 174-1750C [4759-48-2] |
250 mg |
$101.10 |
| |
A vitamin A analog that inhibits cell proliferation and induces cell differentiation. |
500 mg |
$177.10 |
| |
Kelloff GJ, Crowell JA, Hawk ET et al. J. Cell. Biochem Suppl. 26:54-71 (1996). |
|
|
| |
|
|
|
| R1780 |
trans-Retinoic acid |
500 mg |
$43.90 |
| |
C20H28O2 FW 300.44 m.p. 180-1810C [302-79-4] |
1 g |
$80.60 |
| |
The active metabolite of vitamin A. A potential chemopreventive against skin, |
5 g |
$357.50 |
| |
colon, and mammary tumors. |
|
|
| |
M Leid, Kastner P, Chambon P. Trends Biochem. Sci. 17:427-33 (1992). |
|
|
| |
Athar M, Agarwal R, Wang ZY et al. Carcinogenesis. 12:2325-9 (1991). |
|
|
| |
Stopera SA, Bird RP. Int. J. Cancer. 53:798-803 (1993). |
|
|
| |
Toma S, Isnardi L, Raffo P et al. Int. J. Cancer. 70:619-27 (1997). |
|
|
| |
|
|
|
| R1876 |
all-trans-Retinol |
100 mg |
$56.00 |
| |
|
250 mg |
$100.80 |
| |
|
500 mg |
$145.60 |
| |
Inhibits cell proliferation and induces cell differentiation. |
|
|
| |
Kelloff GJ, Boone CW, Crowell JA et al. Cancer Epidemiol. Biomarkers Prev. 3:85-98 (1994). |
|
|
| |
|
|
|
| R1878 |
Retinyl acetate |
5 g |
$46.60 |
| |
C22H32O2 FW 328.49 m.p. 57-580C [127-47-9] |
25 g |
$140.90 |
| |
A vitamin A analog that inhibits cell proliferation and induces cell differentiation. |
100 g |
$406.80 |
| |
A chemopreventive against rat mammary tumors. |
|
|
| |
Grubbs CJ, Eto I, Juliana MM et al. Anticancer Res. 10:661-666 (1990). |
|
|
| |
|
|
|
| R1879 |
Retinyl palmitate |
25 g |
$21.20 |
| |
C36H60O2 FW 524.86 [79-81-2] |
100 g |
$57.70 |
| |
A vitamin A analog that inhibits cell proliferation and induces |
|
|
| |
cell differentiation. Effective in lung cancer chemoprevention. |
|
|
| |
Pastorino U, Soresi E, Clerici, M et al. Acta Oncol. 27:773-782 (1988). |
|
|
| |
|
|
|
| R1985 |
Reveromycin A |
100 µg |
$232.10 |
| |
C36H52O11 FW 660.79 [134615-37-5] |
5 x 10 µg |
$940.80 |
| |
An inhibitor of eukaryotic cell growth. Shown to have a strong antitumor effect against |
|
|
| |
human ovarian carcinoma BG-1. |
|
|
| |
Takahashi H, Yamashita Y, Takaoka H. Oncol Res. 9:7-11 (1997). |
|
|
| |
Osada H. Curr Med Chem. 10:727-732, (2003). |
|
|
| |
|
|
|
| R2112 |
RFDS |
5 mg |
$60.30 |
| |
C22H33N7O8 FW 523.5 |
|
|
| |
|
|
|
| R2353 |
R-F-NH2 |
5 mg |
$35.80 |
| |
C15H24N6O2 FW 320.4 |
10 mg |
$60.90 |
| |
|
25 mg |
$107.50 |
| |
|
|
|
| R2369 |
RFRP-1, human |
0.5 mg |
$43.00 |
| |
C67H101N19O14S FW 1428.73 |
1 mg |
$73.10 |
| |
|
2.5 mg |
$129.00 |
| |
|
|
|
| R2512 |
RGD |
5 mg |
$35.80 |
| |
C12H22N6O6 FW 346.3 [99896-85-2] |
10 mg |
$60.90 |
| |
Antineoplastic agent. |
25 mg |
$107.50 |
| |
|
|
|
| R2510 |
RGD-4C |
1 mg |
$129.00 |
| |
C42H60N14O16S4 FW 1145.29 |
2 mg |
$218.60 |
| |
|
5 mg |
$387.10 |
| |
|
|
|
| R2511 |
R-G-D-C |
5 mg |
$35.80 |
| |
C15H26N7O7S1 FW 448.48 |
10 mg |
$60.90 |
| |
|
25 mg |
$107.50 |
| |
|
|
|
| R2513 |
RGDS |
5 mg |
$53.80 |
| |
C15H27N7O8 FW 433.4 [91037-65-9] |
|
|
| |
Platelet aggregation inhibitor. |
|
|
| |
|
|
|
| R2514 |
RGDV |
5 mg |
$35.80 |
| |
C17H31N7O7 FW 445.5 [93674-99-8] |
10 mg |
$60.90 |
| |
The 4-residue sequence found at the cell-adhesive region of the peptide vitronectin. |
25 mg |
$107.50 |
| |
Lin HB, Garcia-Echeverria C, Asakura S et al. Biomaterials. 13:905-914 (1992). |
|
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| |
|
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|
| R2516 |
R-G-E-S |
0.5 mg |
$28.70 |
| |
C16H29N7O8 FW 447.45 |
1 mg |
$48.80 |
| |
A tetrapeptide structurally similar to RGDS. RGDS is a synthetic peptide that |
2.5 mg |
$86.00 |
| |
represents the fibroblast binding site of fibronectin. RGES is often used in fibro |
|
|
| |
blast binding experiments. |
|
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| |
Pasula R, Wisniowski P, Martin WJ 2nd. Infect Immun. 70:1287-92 (2002). |
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| |
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|
| R2599 |
R-G-Y-S-L-G |
1 mg |
$43.00 |
| |
C28H45N9O9 FW 651.73 |
2 mg |
$73.10 |
| |
A synthetic peptide that represents the active site of a protein kinase. |
5 mg |
$129.00 |
| |
Pattanaik A, Gowda DC, Urry DW. Biochem Biophys Res Commun. 178:539-45 (1991). |
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| |
|
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|
| R2917 |
Rhein |
100 mg |
$82.90 |
| |
C15H8O6 FW 284.22 [478-43-3] |
500 mg |
$365.70 |
| |
Induces apoptosis in cancer cell lines and inhibits transforming growth |
1 g |
$620.90 |
| |
factor beta1 induced plasminogen activator inhibitor-1 in endothelial cells. |
|
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| |
Zhu J, Liu Z, Huang H, Chen Z, Li L. Chin Med J (Engl).116:354-9 (2003). |
|
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| |
Huang YH, Zhen YS. Yao Xue Xue Bao. 36:334-8 (2001). |
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| |
|
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|
| R3205 |
Ribavirin |
50 mg |
$80.60 |
| |
C8H12N4O5 FW 244.2 [36791-04-5] |
100 mg |
$143.40 |
| |
Synthetic broad-spectrum antiviral nucleoside found to have antitumor activity |
500 mg |
$447.60 |
| |
on L1210 leukemia in mice. It regulates signal transduction in human ovarian cancer cells. |
|
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| |
Li W, Shen F, Weber G. Oncol Res. 11:243-7 (1999). |
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| |
Jolley WB, Chu WT, Salter JM. Ann N Y Acad Sci. 284:585-90 (1977). |
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| |
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|
| R3206 |
Riboflavin |
25 g |
$20.70 |
| |
C17H20N4O6 FW 376.4 [83-88-5] |
100 g |
$49.50 |
| |
Riboflavin deficiency causes formation of single strand breaks in nuclear DNA, |
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| |
increases carcinogen-DNA binding and decreases hepatic glutathione content. All of |
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| |
this can be reversed by riboflavin supplementation. |
|
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| |
Webster RP, Gawde MD, Bhattacharya RK. Cancer Lett. 98:129-35 (1996). |
|
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| |
Pangrekar J, Krishnaswamy K, Jagadeesan V. Food Chem Toxicol. 31:745-50 (1993). |
|
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| |
Chiao CH, Chung Hua Chung Liu Tsa Chih.11:92-4 (1989). |
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| |
|
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|
| R3310 |
Ricobendazole |
10 g |
$44.20 |
| |
Albendazole sulfoxide |
25 g |
$82.90 |
| |
C12H15N3O3S FW 281.33 [54029-12-8] |
100 g |
$241.50 |
| |
Active metabolite of albendazole, an anthelmintic. |
|
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| |
Castillo JA, Palomo-Canales J, Garcia JJ et al. Drug Dev Ind Pharm. 25:1241-8 (1999). |
|
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| |
|
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|
| R3312 |
Ridaifen A Dihydrochloride |
25 mg |
$67.20 |
| |
C30H40Cl2N2O2 FW 531.56 |
100 mg |
$196.00 |
| |
Ridaifen-B (RID-B) is a novel tamoxifen (TAM) analog that significantly augm |
250 mg |
$420.00 |
| |
ents apoptosis-inducing effect of TAM in estrogen receptor (ER)-negatives cells. |
|
|
| |
Nagahara, Y. Cancer Science (2008), 99(3), 608-614. |
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| |
|
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|
| R3220 |
Rifampin |
1 g |
$29.50 |
| |
Rifampicin |
5 g |
$98.40 |
| |
C43H58N4O12 FW 822.94 [13292-46-1] |
25 g |
$368.80 |
| |
An antibacterial from 3-formyl rifamycin SV. |
|
|
| |
Maggi et al. Chemotherapia. 11:285 (1966). |
|
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| |
|
|
|
| R3221 |
Rifamycin SV-3 formyl |
1 g |
$49.30 |
| |
C38H47NO13 FW 725.78 [13292-22-3] |
5 g |
$183.70 |
| |
A derivative of rifamycins found to interact with biological membranes. It causes |
10 g |
$332.10 |
| |
a change in permeability to K+ and H+ in the mitochondrial membrane. |
|
|
| |
Inouye B, Uchinomi Y, Wachi T, Utsumi K. J Antibiot (Tokyo). 30:494-9 (1977). |
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| |
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| |
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|
| R3222 |
Rifamycin SV-Sodium |
1 g |
$32.90 |
| |
C37H46NNaO12 FW 719.75 [14897-39-3] |
5 g |
$106.50 |
| |
An antimicrobial agent, inhibits DNA polymerase. |
|
|
| |
Furesz S, Arioli V, Pallanza R. Antimicrob Agents Chemother. 5:770-7 (1965). |
|
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| |
Frolova LY, Meldrays YA, Kochkina LL et al. Nucleic Acids Res. 4:523-38 (1977). |
|
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| |
|
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| |
|
|
|
| R3321 |
Rifaximin |
500 mg |
$75.90 |
| |
C43H51N3O11 FW 785.88 [80621-81-4] |
1 g |
$110.40 |
| |
A rifamycin derivative. It is a non-absorbable broad-spectrum antibiotic that |
5 g |
$482.90 |
| |
possesses in vitro activity against a wide range of bacteria. It acts by inhibiting |
|
|
| |
bacterial ribonucleic (RNA) synthesis. |
|
|
| |
Prasad ES, Wenman WM. Diagn Microbiol Infect Dis. 16:135-6 (1993). |
|
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| |
Gillis JC, Brogden RN. Drugs. 49:467-84 (1995). |
|
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| |
|
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|
| R3224 |
Rigin |
5 mg |
$43.00 |
| |
C18H32N8O6 FW 456.51 [77727-17-4] |
10 mg |
$73.10 |
| |
Tuftsin-like tetrapeptide that stimulates phagocytosis activity. Rigin |
25 mg |
$129.00 |
| |
demonstrates high stress-protective activity in neuroendocrine and immune systems |
|
|
| |
in rats. It stimulates release of interleukin-1 and tumor necrosis factor from mouse peritoneal |
|
|
| |
macrophages and from human monocytes. |
|
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| |
Rocchi R, Biondi L, Filira F, Tzehoval E, Dagan S, Fridkin M.Int J Pept Protein Res. 37:161-6 (1991). |
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| |
Klusha VE, Mutsenietse RK, Svirskis ShV, Zalitis GM, Liepa IR. Biull Eksp Biol Med. 104:186-7 (1987). |
|
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| |
|
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|
| R3249 |
Rimantadine Hydrochloride |
25 mg |
$68.10 |
| |
C12H21N.HCl FW 215.77 [1501-84-4] |
50 mg |
$121.70 |
| |
Used for influenza A treatment and prevention. |
|
|
| |
Tominack RL, Hayden FG. Infect Dis Clin North Am. 1:459-78 (1987). |
|
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| |
|
|
|
| R3347 |
Riluzole |
25 mg |
$44.80 |
| |
Rilutek |
250 mg |
$336.00 |
| |
C8H5F3N2OS FW 234.1983 [1744-22-5] |
500 mg |
$537.60 |
| |
Has anticonvulsant activity and inhibits glutamate release. Has been used to treat |
|
|
| |
amyotrophic lateral sclerosis. |
|
|
| |
Mantz, et al Anesthesiology 76:844 (1992). |
|
|
| |
van Kan HJ, Groeneveld GJ, Kalmijn S, Spieksma M, van den Berg LH, Guchelaar HJ Br. J. Clin. Pharmacol. 59:310-3 (2005). |
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| |
|
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|
| R3373 |
Risedronate sodium |
100 mg |
$96.30 |
| |
C7H10NO7P2Na FW 305.10 [1154326-72-1] |
|
|
| |
A pyridinyl biphosphonate. It inhibits osteoclast-mediated bone resorption. |
|
|
| |
Boiser S, Ferreras M, Peyruchaud O, Magnetto S. Cancer Res. 60:2949-54 (2000). |
|
|
| |
Goa KL, Balfour JA. Drugs Aging. 13:83-91 (1998). |
|
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| |
|
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|
| R3374 |
Risedronic acid |
100 mg |
$87.80 |
| |
C7H11NO7P2 FW 283.11 [105462-24-6] |
|
|
| |
A biophosphonate that displays potent inhibition of bone resorption. Shown to prevent |
|
|
| |
bone metastases in rats. |
|
|
| |
Muhlbauer RC, Bauss F, Schenk R. J Bone Miner Res. 6:1003-1011 (1994). |
|
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| |
|
|
|
| R3475 |
Risperidone |
100 mg |
$56.00 |
| |
C23H27FN4O2 FW 410.48 [106266-06-2] |
250 mg |
$106.40 |
| |
Is an atypical anti-psychotic used for the treatment of schizophrenic and bipolar |
1 g |
$313.60 |
| |
disorders. A typical neuroleptic, it is a strong dopamine antagonist with a high |
|
|
| |
affinity for D2 dopaminergic receptors. |
|
|
| |
Vehof, J. Journal of Clinical Psychopharmacology (2008), 28(6), 625-630. |
|
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| |
|
|
|
| R3477 |
Ritodrine |
250 mg |
$67.20 |
| |
Ritodrina, Ritodrinium |
1 g |
$207.20 |
| |
C17H21NO3.HCl FW 323.81 [23239-51-2] |
5 g |
$672.00 |
| |
Adrenergic b2-agonist that relaxes uterine muscle. It is used to stop premature labor. |
|
|
| |
Bassett JM, Symonds ME Am. J. Physiol. 275:R112-R119 (1998). |
|
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| |
|
|
|
| R3586 |
Rivastigmine Hydrogen Tartrate |
100 mg |
$89.60 |
| |
C18H28N2O8 FW 400.42 [129101-54-8] |
250 mg |
$179.20 |
| |
is a parasympathomimetic or cholinergic agent for the treatment of mild to |
1 g |
$560.00 |
| |
moderate dementia of the AlzheimerÕs type and Parkinson's disease. |
|
|
| |
Winblad, Bengt, Expert Opinion on Drug Delivery (2008), 5(12), 1377-1386 |
|
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| |
|
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|
| R5611 |
Rocuronium Bromide |
10 mg |
$50.40 |
| |
C32H35BrN2O4 FW 609.68 [119302-91-9] |
25 mg |
$112.00 |
| |
an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used |
100 mg |
$325.00 |
| |
in modern anesthesia to facilitate endotraceal intubation. |
|
|
| |
Auer, U. Veterinary Journal (2007), 173(2), 422-427. |
|
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| |
|
|
|
| R5661 |
Ropinirole Hydrochloride |
25 mg |
$50.20 |
| |
C16H24N2O.HCl FW 296.84 [91374-21-9] |
100 mg |
$106.60 |
| |
A dopamine receptor agonist commonly used to treat Parkinson disease and |
500 mg |
$439.00 |
| |
restless legs sydrome. |
|
|
| |
Gallagher G Jr, Lavanchy PG, Webster CA et al. J Med Chem. 28:1533-1536 (1985). |
|
|
| |
Anonymous, Health News. 10:2 (2004). |
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| |
|
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|
| R5874 |
Rosmarinic Acid |
10 mg |
$103.30 |
| |
C18H16O8 FW 360.31 [20283-92-5] |
25 mg |
$186.00 |
| |
Natural product isolated from rosemary, sweet basal and perilla. It has |
100 mg |
$619.60 |
| |
anti-inflammatory activity and inhibits the proliferation of murine mesangial cells. |
|
|
| |
Makino T, Ono T, Muso E et al. Nephrol Dial Transplant. 15:1140-5 (2000). |
|
|
| |
Englberger W, Hadding U, Etschenberg E et al. Int J Immunopharmacol. 10:729-37 (1988). |
|
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| |
|
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|
| R5974 |
Rosuvastatin |
25 mg |
$67.20 |
| |
C22H28FN3O6S FW 481.54 [287714-41-4] |
100 mg |
$224.00 |
| |
|
250 mg |
$425.60 |
| |
|
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| |
|
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| |
|
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| |
|
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| |
|
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| R5894 |
Roxatidine Acetate Hydrochloride |
100 mg |
$103.30 |
| |
C19H28N2O4.HCl FW 384.90 [93793-83-0] |
500 mg |
$364.30 |
| |
A histamine H2-receptor antagonist used in ulcer treatment. |
1 g |
$576.80 |
| |
Found to inhibit platelet function in vitro. |
|
|
| |
Brandstatter G, Marks IN, Lanza F et al. Clin Ther. 17:467-478 (1995). |
|
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| |
Nakamura K, Kariyazono H, Shinkawa, T et al. Human Exptal Tox. 18: 487-492 (1999). |
|
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| |
|
|
|
| R5992 |
Roxithromycin |
1 g |
$16.60 |
| |
C41H76N2O15 FW 837.05 [80214-83-1] |
5 g |
$55.20 |
| |
An antibiotic with a wide antibacterial spectrum against oral pathogens and an |
10 g |
$80.10 |
| |
immunomodulatory effect. It has also been shown to increase neutrophil apoptosis, |
|
|
| |
reduce tumor size of B16BL6 melanoma, and inhibit pulmonary metastasis of B16BL6 cells. |
|
|
| |
Yatsunami J, Tsuruta N, Fukuno Y et al. Clin Exp Metastasis. 17:119-24 (1999). |
|
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| |
Oyama T, Sakuta T, Matsushita K et al. J Periodontal. 71:1546-53 (2000). |
|
|
| |
|
|
|
| R6871 |
RR-SRC |
5 mg |
$157.70 |
| |
C64H106N22O21 FW 1519.7 |
10 mg |
$268.10 |
| |
A tyrosine kinase-specific substrate often used in experiments to determine |
25 mg |
$473.10 |
| |
Tyr kinase activity. |
|
|
| |
Shen SS, Kinsey WH, Lee SJ. Dev Growth Differ. 41: 345-55 (1999). |
|
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| |
|
|
|
| R6873 |
R-S-R |
1 mg |
$35.80 |
| |
C15H31N9O5 FW 417.5 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
|
|
|
| R8206 |
Rubescensin A |
25 mg |
$60.80 |
| |
Oridonin |
100 mg |
$182.20 |
| |
C20H28O6 FW 364.43 [28957-04-2] |
500 mg |
$607.20 |
| |
A diterpene isolated from the leaves of Rabdosia rubescens Hora. It appears to have |
|
|
| |
antitumor activity in cell culture studies. |
|
|
| |
Li XT, Lin C, Li PY. Chinese J Oncology. 8:184-186 (1986). |
|
|
| |
Fuji K, Node M, Sai M et al. Chem Pharmaceut Bull. 37:1472-1476 (1989). |
|
|
| |
|
|
|
| R8207 |
b-Rubromycin |
1 mg |
$73.80 |
| |
C27H20O12 FW 536.44 [27267-70-5] |
5 mg |
$295.10 |
| |
A quinone antibiotic agent. Found to inhibit reverse transcrisptase from HIV-1 to a greater |
|
|
| |
degree than it inhibits cellular DNA polymerase alpha. |
|
|
| |
Goldman ME, Salituro GS, Bowen JA et al. Mol Pharmacol. 38:20-25 (1990). |
|
|
| |
|
|
|
| R8122 |
Rufloxacin Hydrochloride |
25 mg |
$48.40 |
| |
C17H18FN3O3S.HCl FW 399.87 [106017-08-7] |
100 mg |
$165.60 |
| |
A fluoroquinolone antibacterial that shows photosensitizing properties toward |
500 mg |
$669.30 |
| |
biological substrates. It inhibits B-cell differentiation in human mononuclear cells. |
|
|
| |
Gollapudi S, Perumal V, Thadepalli H, J Antimicrob Chemother. 29:669-76 (1992). |
|
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| |
Condorelli G. De Guidi G, Giuffrida S et al. Photochem Photobiol. 70:280-6 (1999). |
|
|
| |
|
|
|
| R8178 |
Rutaecarpine |
10 mg |
$98.80 |
| |
Rutecarpine |
25 mg |
$209.60 |
| |
C18H13N3O FW 287.32 [84-26-4] |
100 mg |
$667.90 |
| |
An alkaloid isolated from the chinese herb Evodia rutaecarpa. It has vasorelaxing effect and |
|
|
| |
inhibits platelet aggregation and COX-2. It is a selective inhibitor of cytochrome P450 1A. |
|
|
| |
Chiou WF, Chou CJ, Liao JF et al. Europ J Pharm. 257:59-66 (1994). |
|
|
| |
Sheu JR, Hung WC, Lee YM, Yen MH. Europ J Pharm. 318:469-475 (1996). |
|
|
| |
Moon TC, Murakami M, Kudo I et al. Inflam Res. 48:621-625 (1999). |
|
|
| |
Ueng, YF., Jan, WC., Lin, LC. et al Drug Metab. Disp. 30:349-353 (2002). |
|
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| |
|
|
|
| R8076 |
Rutin Hydrate |
50 g |
$27.60 |
| |
C27H30O16 FW 610.52 [153-18-4] |
100 g |
$48.00 |
| |
A glycoside of quercetin. Inhibits the initiation and promotion |
500 g |
$180.00 |
| |
stages of carcinogenesis, and enhances detoxification. An effective |
|
|
| |
inhibitor of carcinogen-induced aberrant crypt foci in the rat colon. |
|
|
| |
Elangovan V, Sekar N, Govindasamy S. Cancer Lett. 87:107-113 (1994). |
|
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| |
Wargovich MJ, Chen CD, Jimenez A et al. Cancer Epidimiol. Biomarkers Prev. 5:355-360 (1996). |
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