| S0006 |
S6-1 |
1 mg |
$50.20 |
| |
C39H75N17O11 FW 958.14 |
2 mg |
$86.00 |
| |
A sythetic octapeptide that represents the phosphorylated region of the S6 protein. |
5 mg |
$150.50 |
| |
Hecht LB, Straus DS. Endocrinology. 119: 470-80 (1986). |
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| |
|
|
|
| S0132 |
Saikosaponin A |
1 mg |
$188.60 |
| |
C42H68O13 FW 780.98 [20874-52-6] m.p. 225-2320C |
5 mg |
$737.70 |
| |
The saikosaponins have potent anti-inflammatory activity on mouse ear edema induced by |
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|
| |
the tumor promoter, phorbol myristate acetate. In cell culture studies, they have been found to |
|
|
| |
induce differentiation without growth inhibition and apoptosis in B16 melanoma cells. |
|
|
| |
Zong Z, Fujikawa-Yamamoto K, Ota T et al. Cell Struct Funct. 23:265-272 (1998). |
|
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| |
Bermejo BP, Abad Martinez MJ, Silvan Sen AM et al. Life Sci. 63:1147-1156 (1998). |
|
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| |
Zong Z, Fujikawa-Yamamoto K, Tanino M et al. Biochem Biophys Res Commun. 219:480-485 (1996). |
|
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| |
Ohtsuka M, Fukuda K, Yano H, Kohiro M. Jpn J Cancer Res. 86:1131-1135 (1995). |
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| |
Qian L, Murakami T, Kimura Y et al. Pathol Int. 45:207-214 (1995). |
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| |
|
|
|
| S0032 |
Saikosaponin B1 |
1 mg |
$69.00 |
| |
C42H68O13 FW 780.98 [58558-08-0] |
5 mg |
$255.40 |
| |
Saidosaponin B1 induces PGE2 release in C6 rat glioma cells. In cultured fibroblasts saikosaponin B1 |
|
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| |
suppresses the blockage of signal transduction after binding of EGF resulting in growth stimulation. |
|
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| |
Kyo R, Nakahata N, Kodama Y et al. Biol Pharm Bull. 22:1385-7 (1999). |
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| |
Nishiyama T, Horii I, Nakayama Y et al. Matrix. 10:412-9 (1990). |
|
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| |
|
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|
| S0033 |
Saikosaponin B2 |
1 mg |
$69.00 |
| |
C42H68O13 FW 780.98 |
5 mg |
$255.40 |
| |
Saikosaponin B2 inhibits the proliferation of B16 melanoma cells in culture by induction |
|
|
| |
of apoptosis. The inhibition is a result of G1 phase accumulation. |
|
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| |
Zong Z, Fujikawa-Yamamoto K, Tanino M, et al. Biochem Biophys Res Commun. 219:480-5 (1996). |
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| |
|
|
|
| S0133 |
Saikosaponin C |
1 mg |
$188.60 |
| |
|
5 mg |
$737.70 |
| |
Saikosaponin C was found to have inhibiting activity in hepatitis B virus DNA replicaiton. |
|
|
| |
Chiang LC, Ng LT, Liu LT et al. Planta Med. 69:705-9 (2003). |
|
|
| |
|
|
|
| S0134 |
Saikosaponin D |
1 mg |
$188.60 |
| |
|
5 mg |
$737.70 |
| |
Saikosaponin D was found to stimulate corticotropin-releasing factor (CRF) gene expression and |
|
|
| |
CRF release. It also increases adrenocorticotropin release. |
|
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| |
Dobashi I, Tozawa F, Horiba N et al. Neurosci Lett. 197:235-238 (1995). |
|
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| |
|
|
|
| S0044 |
Salbutamol free base |
25 mg |
$32.90 |
| |
Albuterol |
50 mg |
$57.50 |
| |
|
100mg |
$98.40 |
| |
A beta-adrenoceptor agonist. |
500mg |
$360.60 |
| |
Church MK, Hiroi J. Br J Pharmacol. 90:421-9 (1987). |
|
|
| S0045 |
Salbutamol sulfate |
25 mg |
$32.90 |
| |
Albuterol sulfate |
50 mg |
$57.50 |
| |
(C13H21NO3)2.H2SO4 FW 576.7 [51022-70-9] |
100mg |
$95.10 |
| |
A beta-adrenoceptor agonist. |
500mg |
$344.40 |
| |
Church MK, Hiroi J. Br J Pharmacol. 90:421-9 (1987). |
|
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| |
|
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|
| S0048 |
Salicin |
5 g |
$25.10 |
| |
C13H18O7 FW 286.28 [138-52-3] |
25 g |
$106.60 |
| |
An analgesic and antipyretic. Reported to have antileukemic activity. |
|
|
| |
Smith ID, Temple DM, Shearman RP. Prostaglandins. 10:41-57 (1975). |
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| |
El-Shemy HA, Aboul-Enein AM, Aboul-Enein MI et al. J Biochem Mol Biol. 36: 387-389 (2003). |
|
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| |
|
|
|
| S0049 |
Salmon Calcitonin Acetate |
Please inquire |
|
| |
C145H240N44O48S2 FW 3431.9 [47931-85-1] |
|
|
| |
Salmon calcitonin acetate positively influences bone mass density due to its inhibiting effect |
|
|
| |
on osteoclast activity. For the treatment of osteoporosis, pagetÕs disease, hypercalcemia, reflex |
|
|
| |
sympathetic dystrophy (algodistrophy or SudeckÕs disease). |
|
|
| |
Kopaliani M. Georgian Med News. 121: 38-42 (2005). |
|
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| |
|
|
|
| S0244 |
Salsalate |
25 g |
$35.00 |
| |
C14H10O5 FW 2589.23 [552-94-3] |
100 g |
$100.00 |
| |
Salsalate is a non-steroidal anti-inflammatory drug (NSAID). Salsalate is in a class |
|
|
| |
of drugs called salicylates. Salsalate may work by inhibiting the production of and release of prostaglandins. |
|
|
| |
Gupta, S. K. AIDS (2008), 22(5), 653-655. |
|
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|
|
|
| S0046 |
Salsolidine |
25 mg |
$41.40 |
| |
C12H17NO2 FW 207.27 [493-48-1] |
100mg |
$117.40 |
| |
A tetrahydroisoquinolone that is a steroselective competitive inhibitor of the enzyme monoamine oxidase. |
|
|
| |
It is also a competitive inhibitor of catechol-O-methyltransferase. |
|
|
| |
Bembenek ME, Abell CW, Chrisey LA et al. J Med Chem. 33:147-52 (1990). |
|
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| |
Dostert P, Strolin Benedetti M, Dordain G. J Neural Transm. 74:61-74 (1988). |
|
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| |
Sanft K, Thomas H. Z Naturforsch [C]. 44:173-6 (1989). |
|
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| |
|
|
|
| S0047 |
Salsoline |
25 mg |
$41.40 |
| |
C11H15NO2 FW 193.24 [101467-40-7] |
100mg |
$117.40 |
| |
Salsoline, a tetrahydroisoquinolone, is an active metabolite of dopamine. |
|
|
| |
It inhibits cholinesterase activity. |
|
|
| |
Sallstrom Baum S, Hill R, Kiianmaa K, Rommelspacher H. Alcohol. 1:165-9 (1999). |
|
|
| |
Maizel EB, Rozengart EV, Khakimov IuP et al. Biokhimiia. 43:1150-6 (1978). |
|
|
| |
|
|
|
| S0200 |
SAMs Peptide |
0.5 mg |
$78.80 |
| |
C74H131N29O18S2 FW 1779.18 |
1 mg |
$134.40 |
| |
A synthetic peptide often used to determine AMP-activated protein kinase activity. |
2.5 mg |
$236.50 |
| |
Kishimoto A, Ogura T, Esumi H. Mol Biotechnol. 32: 17-21 (2006). |
|
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| |
|
|
|
| S0053 |
a-Santonin |
5 g |
$22.80 |
| |
C15H18O3 FW 246.30 [481-06-1] |
10 g |
$33.40 |
| |
An anthelmintic shown to have antiinflammatory, antipyretic and analgesic |
25 g |
$75.90 |
| |
activity comparable to those of the NSAID, diclofenac sodium. |
|
|
| |
Al-Harbi MM, Ourreshi S, Ahmed MM et al. Japanese J Pharmacol. 64:135-139 (1994). |
|
|
| |
|
|
|
| S0170 |
Sarafloxacin Hydrochloride |
5 g |
$66.30 |
| |
C20H17F2N3O3.HCl FW 421.83 [91296-87-6] |
10 g |
$103.50 |
| |
A fluoroquinolone antibacterial agent found to be effective against |
25 g |
$207.00 |
| |
Mycobacterium tuberculosis. |
|
|
| |
Chu DT, Fernandes PB, Claiborne AK et al. J Med Chem. 28:1558-64 (1985). |
|
|
| |
Berlin OG, Young LS, Bruckner DA. J Antimicrob Chemother. 19:611-5 (1987). |
|
|
| |
|
|
|
| S0171 |
Sarafotoxin 6c |
0.5 mg |
$222.20 |
| |
C103H147N27O37S5 FW 2515.8 |
1 mg |
$378.10 |
| |
A selective endothelin subtype B receptor agonist that induces muscle contractions. |
2.5 mg |
$666.60 |
| |
Fellner SK, Arendshorst W. Am J Physiol Renal Physiol. 292: F175-84 (2007). |
|
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| |
|
|
|
| S0368 |
Sarcophine |
10 mg |
$140.30 |
| |
C20H28O3 FW 316.43 [55038-27-2] |
|
|
| |
It is a cembranoid marine natural product that is reposted to possess cancer chemopreventive properties. |
|
|
| |
Sarcophine was found to be an effective inhibitor of JB6 cell transformation. |
|
|
| |
Sawant, S. S.; Youssef, D. T. A.; Reiland, J.; Ferniz, M.; Marchetti, D.; El Sayed, M. D. J. Nat. Prod. 69:1010-1013 (2006). |
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| |
El Sayed,K. A.;Hamann,M.T.;Waddling,C.A.;Jensen,C.;Lee,S.K.; Dunstan,C. A.; Pezzuto,J.M. J.Org.Chem.63:7449-7455(1998). |
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| |
Katsuyama,I.;Fahmy,H.;Zjawiony,J.K.;Khalifa,S.I.;Kilada,R.W.;Konoshima,T.;Takasaki,M.;Tokuda,H.J.Nat.Prod.65:1809-1814(2002). |
|
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| |
Sawant, S. S.; Sylvester, P. W.; Avery, M. A.; Desai, P.; Youssef, D. T. A.; El Sayed, K. A. J. Nat. Prod. 67:2017-2023 (2004). |
|
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| |
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| |
2-epi-16-deoxysarcophine (See Deoxysarcophine, 2-epi-16-) |
|
|
| |
|
|
|
| S0278 |
Satraplatin |
5 mg |
$138.00 |
| |
C10H22Cl2N2O4Pt FW 500.28 [129580-63-8] |
10 mg |
$231.80 |
| |
An orally active novel platinum IV anticancer agent. It shows |
50 mg |
$896.90 |
| |
promise against lung cancer and ovarian cancer. |
|
|
| |
Bengtson EM, Rigas JR. Drugs. 58 Suppl 3:57-69 (1999). |
|
|
| |
Piccart MJ, Lamb H. Vermorken JB. Ann Oncol. 12:1195-203 (2001). |
|
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| |
|
|
|
| S0381 |
Sauvagine |
0.5 mg |
$222.20 |
| |
C202H347N56O63S FW 4599.4 [74434-59-6] |
1 mg |
$378.10 |
| |
A frog skin peptide that has been shown to inhibit production of prolactin. |
2.5 mg |
$666.60 |
| |
Falaschi P, D'Urso R, Negri L et al. Endicrinology. 111: 693-695 (1982). |
|
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| |
|
|
|
| S0830 |
R(+) Schisandrin A |
5 mg |
$80.10 |
| |
R(+) Schizandrin A; R(+) deoxyschisandrin A; R(+) deoxyschizandrin A |
10 mg |
$131.20 |
| |
C24H32O6 FW 416.51 m.p. 117-1180C [61281-38-7] |
|
|
| |
[a]D:+1100 (C=1.15, CHCl3) |
|
|
| |
|
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| |
|
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| |
|
|
|
| S0831 |
S(-) Schisandrin B |
5 mg |
$80.10 |
| |
S(-) Schizandrin B; S(-)-schisandrin; S(-) wuwei zi su; gomisin N |
10 mg |
$131.20 |
| |
C23H28O6 FW 400.46 m.p. 100-1020C [61281-37-6] |
|
|
| |
[a]D:-510 (c=0.15, CHCl3) |
|
|
| |
Schisandrin B shows antioxidant activity which may be responsible for its hepatic protecting activity. |
|
|
| |
It also increases glutathione level and Dt-diaphorase enzyme activity. |
|
|
| |
Lee IS, Lee HK, Dat NT. Planta Med. 69:63-4 (2003). |
|
|
| |
Chen DF, Zhang SX, Xie L et al. Bioorg Med Chem. 5:1715-23 (1997). |
|
|
| |
Ip SP, Yiu HY, Ko KM. Mol Cell Biochem. 208:151-5 (2000). |
|
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| |
|
|
|
| S0930 |
Schisantherin A |
5 mg |
$80.10 |
| |
Schizantherin A; Gomisin C; Wuweizi ester A |
10 mg |
$131.20 |
| |
C30H32O9 FW 536.57 m.p. 116-1180C |
|
|
| |
[a]D:-190.90 (c=0.995, CHCl3) |
|
|
| |
A lignan from Schisandra chinensis. It has shown a positive effect in lowering the serum |
|
|
| |
glutamic-pyruvic transaminase level of patients suffering from chronic viral hepatitis. |
|
|
| |
Liu CS, Fang SD, Huang MF. Sci Sin. 21:483-502 (1978). |
|
|
| |
|
|
|
| S1058 |
Scopolamine N-butylbromide |
1 g |
$33.20 |
| |
Hyoscine butylbromide |
5 g |
$85.60 |
| |
C21H30BrNO4 FW 440.38 [149-64-4] |
|
|
| |
An antispasmodic agent. |
|
|
| |
Ayre-Smith G. Acta Radiol Diagn (Stockh). 17:701-13 (1976). |
|
|
| |
|
|
|
| S1059 |
Scopolamine Hydrobromide |
1 g |
$50.20 |
| |
C17H21NO4.HBr.3H2O FW 438.32 [114-49-8] |
5 g |
$163.10 |
| |
An anticholinergic agent. |
25 g |
$551.90 |
| |
De Souza H, Palermo-Neto J. Gen Pharmacol. 16:533-6 (1985). |
|
|
| |
|
|
|
| S1060 |
SCPA |
1 mg |
$43.00 |
| |
Small cardioactive peptide A |
2 mg |
$73.50 |
| |
C59H92N18O12S FW 1277.57 |
5 mg |
$129.00 |
| |
A neuropeptide that modulates neuromuscular synapsis in Aplysia. |
|
|
| |
Fox LE, Lloyd PE. J Neurophysiol. 83:1567-79 (2000). |
|
|
| |
|
|
|
| S1061 |
SCPB |
1 mg |
$43.00 |
| |
Small cardioactive peptide B |
2 mg |
$73.50 |
| |
C52H80N14O11S2 FW 1141.43 |
5 mg |
$129.00 |
| |
An antagonistic inhibitor of cAMP-dependent Cl- current in sensory neurons of Aplysia |
|
|
| |
via activation of protein kinase A. |
|
|
| |
Buttner N, Siegelbaum SA. J Neurophysiol. 90: 586-98 (2003). |
|
|
| |
|
|
|
| S1069 |
Scriptaid |
1 mg |
$60.80 |
| |
C18H18N2O4 FW 326.35 |
5 mg |
$233.40 |
| |
An inhibitor of histone deacetylase found to decrease tumor growth. Shown to disrupt |
|
|
| |
the intracellular protein aggregate transport associated with ALS. |
|
|
| |
Keen JC, Yan L, Mack KM et al. Breast Cancer Res Tr. 81:177-186 (2003). |
|
|
| |
Corcoran LJ, Mitchison TJ, Liu Q. Curr Biol. 14:488-492 (2004). |
|
|
| |
|
|
|
| S1343 |
Ac-S-D-K-P |
5 mg |
$86.00 |
| |
C20H33N5O9 FW 487.51 |
10 mg |
$146.90 |
| |
A synthetic hemopeptide shown to inhibit hematopoietic proliferation in |
25 mg |
$258.00 |
| |
stem cells. |
|
|
| |
Dai G, Huang C, Li Y, Pi YH, Wang BH. Cell Biol Int. 30: 514-20 (2006). |
|
|
| |
|
|
|
| S1810 |
Secnidazole |
5 g |
$41.40 |
| |
C7H11N3O3 FW 185.18 [3366-95-8] |
10 g |
$62.20 |
| |
An antimicrobial used as amoebecide and trichomonacide. |
25 g |
$103.50 |
| |
Benazet F, Guillaume L. Bull Soc Pathol Exot Filiales. 69:309-19 (1976). |
|
|
| |
Gillis JC, Wiseman LR. Drugs. 51:621-38 (1996). |
|
|
| |
|
|
|
| S1604 |
Secretin Acetate |
Please inquire |
|
| |
C130H220N44O41 FW 3055.41 [10813-74-8] |
|
|
| |
|
|
|
| |
|
|
|
| S1605 |
Secretin, human |
1 mg |
$136.20 |
| |
C130H220N44O40 FW 3039.4 |
2 mg |
$231.20 |
| |
Secretin is a polypeptide gastrointestinal hormone. It stimulates exocrine |
5 mg |
$408.60 |
| |
pancreatic secretion. |
|
|
| |
Chey WY, Chang TM. J Gastroenterol. 38:1025-35 (2003). |
|
|
| |
Konturek SJ, Thor P, Dembinski A et al. Gastroenterology. 68:1527-35 (1975). |
|
|
| |
|
|
|
| S1606 |
Secretin, porcine |
5 mg |
$408.60 |
| |
C130H220N44O41 FW 3055.4 |
10 mg |
$695.30 |
| |
|
25 mg |
$1,225.70 |
| |
|
|
|
| S1607 |
Secretin, rat |
0.5 mg |
$80.60 |
| |
C129H216N42O42 FW 3027.42 |
1 mg |
$136.20 |
| |
|
2.5 mg |
$240.10 |
| |
|
|
|
| S1609 |
Securinine |
500 mg |
$80.10 |
| |
C13H15NO2 FW 217.26 [5610-40-2] |
1 g |
$117.40 |
| |
A g-aminobutyric acid (GABA) receptor antagonist. Recently, it was found to induce apoptosis in |
|
|
| |
human leukemia HL-60 cells. |
|
|
| |
Beutler JA, Karbon EW, Brubaker AN et al. Brain Res. 330:135-40 (1985). |
|
|
| |
Dong NZ, Gu ZL, Chou WH, Kwok CY. Chung Kuo Yao Li Hsueh Pao. 20:267-70 (1999). |
|
|
| |
|
|
|
| S1612 |
Sedanolide |
100mg |
$110.50 |
| |
(3-Butyl-3a,4,5,6-tetrahydro-1(3H)-isobenzofuranone) |
500mg |
$359.90 |
| |
C12H18O2 FW 194.27 m.p. 30-310C [6415-59-4] |
1 g |
$635.50 |
| |
Natural product isolated from celery seed oil. Inducer of glutathione S-transferase |
|
|
| |
enzyme system. Inhibitor of chemically induced carcinogenesis. |
|
|
| |
Zheng G-q, Kenney, PM, Lam LKT. Nutr. Cancer. 19:77-86 (1993). |
|
|
| |
|
|
|
| S1843 |
L-Selectin |
1 mg |
$126.20 |
| |
C62H105N16O18S2 FW 1426.75 |
2 mg |
$215.00 |
| |
A glycoprotein receptor that mediates lymphocyte rolling in high |
5 mg |
$378.60 |
| |
endothlial venules. |
|
|
| |
Sperandio M, Frommhold D, Babushkina I and Ellies LG et. al. Eur J Immunol. 36: 3207-15 (2006). |
|
|
| |
|
|
|
| S1845 |
L-(+)-Selenomethionine |
10 mg |
$19.30 |
| |
2-Amino-4-(methylseleno)butanoic acid |
25 mg |
$39.60 |
| |
C5H11NO2Se FW 196.11 m.p. 2650C [3211-76-5] |
100mg |
$131.50 |
| |
Inhibitor of 2-acetylaminofluorene-induced hepatocarcinogenesis. |
|
|
| |
Mukherjee B, Ghosh S, Chatterjee M. J Exp Ther Oncol. 14:209-217 (1996). |
|
|
| |
|
|
|
| S1848 |
Se-methylseleno-L-cysteine |
100mg |
$83.20 |
| |
2-Amino-3-methylselenyl propionic acid |
250 g |
$166.40 |
| |
C4H9NO2Se FW 182.08 [26046-90-2] |
|
|
| |
Inhibitor of DMBA-induced mammary tumors. |
|
|
| |
Ip C, Ganther HE. Carcinogenesis. 7:1167-1170 (1992). |
|
|
| |
|
|
|
| S1968 |
Seratrodast |
25 mg |
$67.20 |
| |
C22H26O4 FW 354.44 [112665-43-7] |
100mg |
$196.00 |
| |
Is a thromboxane receptor antagonist used primarily in the treatment of asthma. |
250mg |
$392.00 |
| |
Fukuoka, T. Journal of Asthma (2003), 40(3), 257-264 |
|
|
| |
|
|
|
| S1969 |
Sermorelin Acetate |
Please inquire |
|
| |
C149H246N44O42S FW 3358.03 [86168-78-7] |
|
|
| |
Secretin stimulates the secretion of bicarbonate by the pancreas and inhibits the production of |
|
|
| |
gastrin and acid production in the stomach. It also potentiates the release of digestive enzymes |
|
|
| |
from the pancreas triggered by cholecystokinin. Diagnosis of pancreatic dysfunctionand the |
|
|
| |
presence of a gastrinoma treating. For the treatment of autism-not yet approved applications. |
|
|
| |
|
|
|
| S1970 |
Serum Thymic Factor |
1 mg |
$35.80 |
| |
C33H54N12O15 FW 858.89 |
2 mg |
$60.90 |
| |
A thymic peptide hormone that induces the formation of E rosettes. |
5 mg |
$107.50 |
| |
Incefy GS, Mertelsmann R, Yata K, Dardenne M, Bach JF, Good RA. Haematologia (Budap). 13: 203-11 (1980). |
|
|
| |
|
|
|
| S2044 |
S-F-L-L-R |
1 mg |
$57.30 |
| |
C30H50N8O7 FW 634.78 |
2 mg |
$96.80 |
| |
A protease-activated receptor 1 agonist peptide that exhibits cell |
5 mg |
$172.00 |
| |
proliferation effects. |
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| |
Hirota Y, Osuga Y, Hirata T and Yoshino O et. al. J Clin Endocrinol Metab. 90: 3673-9 (2005). |
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| |
|
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|
| S3033 |
Shikimic acid |
1 g |
$62.20 |
| |
C7H10O5 FW 174.15 [138-59-0] |
5 g |
$241.50 |
| |
An antimicrobial agent with antagonistic effects. It inhibits rapamycin |
|
|
| |
biosynthesis in Streptomyces hygroscopicus. |
|
|
| |
Ma Y, Xu QP, Sun JN et al. Chung Kuo Yao Li Hsueh Pao. 20:701-4 (1999). |
|
|
| |
Fang A, Demain AL. Folia Microbiol (Praha). 40:607-10 (1995). |
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| |
|
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|
| S3343 |
Silybin |
500mg |
$26.00 |
| |
C25H22O10 FW 482.44 [22888-70-6] |
1 g |
$43.10 |
| |
The major component of silymarin, a group of polyphenolic flavonoids derived |
5 g |
$172.10 |
| |
from milk thistle (Silybum marianum) that has anti-inflammatory, cytoprotective and |
|
|
| |
anti-carcinogenic effects . It is reported that Silybin has protective effect against skin cancer |
|
|
| |
and inhibits mitogen-activated protein kinase. |
|
|
| |
Manna SK, Mukhopadhyay A, Van NT, Aggarwal BB. J Immunol. 163:6800-9 (1999). |
|
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| |
Zi X, Agarwal R, Biochem Biophys Res Commun. 263:528-36 (1999). |
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| |
|
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|
| S3345 |
Silymarin |
10 g |
$24.30 |
| |
C25H22O10 FW 482.44 [65666-07-1] |
50 g |
$75.50 |
| |
Flavanoid antioxidant isolated from milk thistle that is effective |
|
|
| |
chemopreventive agents. |
|
|
| |
Steele VE, Kelloff GJ, Wilkinson BP, Arnold JT. Cancer Res. 50:2068-2074 (1990). |
|
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| |
Zi X, Mukhtar H, Agarwal R. Biochem Biophys Res Commun. 239:334-9 (1997). |
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| |
|
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|
| S3449 |
Simvastatin |
50 mg |
$116.50 |
| |
Synvinolin |
100mg |
$175.50 |
| |
C25H38O5 FW 418.57 m.p. 135-1380C [79902-63-9] |
500mg |
$734.20 |
| |
A potent HMG-CoA reductase inhibitor and hypocholesterolemic agent. Inhibits |
|
|
| |
cell proliferation of human glioma cells and of acute myeloid leukemia cells. |
|
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| |
Anti-carcinogenic during the promotion phase of radiation-induced mammary tumors. |
|
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| |
Inano H, Suzuki K, Onoda M. Wakabayashi K Carcinogenesis. 18:1723-7 (1997). |
|
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| |
Kikuchi T, Nagata Y, Abe T. J Neurooncol. 34:233-9 (1997). |
|
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| |
Lishner M, Bar-Sef A, Elis A, Fabian I. J Investig Med. 49:319-24 (2001). |
|
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| |
Mol, MJ et al. Lancet. 2:936 (1986). |
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| |
|
|
|
| S3351 |
Sincalide (CCK-8) |
Please inquire |
|
| |
C49H62N10O16S3 FW 1143.29 [25126-32-3] |
|
|
| |
Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) which acts on |
|
|
| |
receptors within the gallbladder wall causing it to contract. |
|
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| |
|
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|
| S3353 |
Sinomenine |
10 g |
$43.10 |
| |
C19H23NO4 FW 329.39 [115-53-7] m.p. 1620C |
25 g |
$146.30 |
| |
Sinomenine is an alkaloid isolated from the Chinese medicinal plant |
50 g |
$258.20 |
| |
Sinomenium acutum. It has immunomodulating and anti-inflammatory activities. |
|
|
| |
Its anti-arthritic property is related to the antiproliferative effects on synovial fibroblasts |
|
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| |
and lymphocytes. Other antirheumatic mechanisms are attributed to its ability to decrease |
|
|
| |
PGE2 and leukotriene C4 synthesis, and inhibit NO production. |
|
|
| |
Vieregge B, Resch K, Kaever V. Planta Med. 65:80-82 (1999). |
|
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| |
Liu L, Buchner E, Beitze D et al. Int J Immunopharmacol. 18:529-43 (1996). |
|
|
| |
Candinas D, Mark W, Kaever V et al. Transplantation. 62:1855-1860 (1996). |
|
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| |
Liu L, Resch K, Kaever V. Int J Immunopharmacol. 16:685-691 (1994). |
|
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| |
Liu L. Riese J, Resch K, Kaever V. Arzneimittelforsching. 44:1223-1226 (1994). |
|
|
| |
|
|
|
| S3585 |
SIVmac239-1 |
1 mg |
$57.30 |
| |
C65H115N21O23S1 FW 1590.83 |
2 mg |
$96.80 |
| |
A pathogenic molecular clone of simian immunodeficiency virus (SIV). |
5 mg |
$172.00 |
| |
Luciw PA, Pratt-Lowe E, Shaw KE, Levy JA, Cheng-Mayer C. Proc Natl Acad Sci U S A. 92: 7490-4 (1995). |
|
|
| |
|
|
|
| S3586 |
SIVmac239-2 |
1 mg |
$57.30 |
| |
C70H123N19O25 FW 1630.87 |
2 mg |
$96.80 |
| |
|
5 mg |
$172.00 |
| |
|
|
|
| S5200 |
SNA 1 |
1 mg |
$120.50 |
| |
SNA 1 is a four chain lectin isolated from the bark of the common elder. It is a ribosome- |
|
|
| |
inactivating protein with low activity on mammalian ribosomes. |
|
|
| |
Broekaert WF et al. Biochem J. 221:163 (1984). |
|
|
| |
VanDamme EJM et al. Eur J Biochem. 235:128 (1996). |
|
|
| |
|
|
|
| SB5776 |
Snake venom - Bothrops alternatus (urutu) |
100mg |
$318.80 |
| |
Known for myotoxic activity. Bothroalternin isolated from |
|
|
| |
the venom is a new thrombin inhibitor. |
|
|
| |
Arruda EZ, Silva NM, Moraes RA, Melo PA. Braz Jmed Biol Res. 35:723-726 (2002). |
|
|
| |
Castro HC, Dutra DL, Oliveira-Carvalho AL, Zingali RB. Toxicon 36:1903-12 (1998). |
|
|
| |
|
|
|
| SB5778 |
Snake venom - Bothrops neuwiedi diporous |
100mg |
$167.00 |
| |
|
|
|
| SC7056 |
Snake venom - Crotalus durissus terrificus |
100mg |
$83.60 |
| |
A potent neurotoxin. Crotoxin (CT), a phospholipase A2 (PLA2) derived |
|
|
| |
from the venom is a heterodimeric protein. PLA2 is found to have |
|
|
| |
anti-proliferative activity. |
|
|
| |
Hawgood BJ. Toxicon 39:1277-82 (2001). |
|
|
| |
Donato NJ, Martin CA, Perez M, Newman RA, Vidal JC, Etcheverry M. Biochem Pharmacol. 51:1535-43 (1996). |
|
|
| |
|
|
|
| S5746 |
Solanesol |
50 mg |
$89.70 |
| |
C45H74O FW 631.07 [13190-97-1] |
100mg |
$138.00 |
| |
A trisesquiterpene alcohol present in tobacco leaf. It is a possible |
500mg |
$448.40 |
| |
precusor of polycyclic aromatic hydrocarbons. |
|
|
| |
Severson RF, Ellington JJ, Schlotzhauer PF et al. J Chromatogr. 139:269-82 (1977). |
|
|
| |
|
|
|
| S5745 |
[Tyr1] Somatostatin |
1 mg |
$64.50 |
| |
C82H108N18O20S2 FW 1730.01 |
2 mg |
$109.30 |
| |
|
5 mg |
$193.50 |
| |
|
|
|
| S5747 |
[Tyr11] Somatostatin |
1 mg |
$64.50 |
| |
C76H102N18O20S2 FW 1651.91 |
2 mg |
$109.30 |
| |
|
5 mg |
$193.50 |
| |
|
|
|
| S5749 |
Somatostatin-14 |
5 mg |
$86.00 |
| |
C76H104N18O19S2 FW 1637.92 [38916-34-6] |
10 mg |
$146.90 |
| |
Growth hormone-release inhibiting factor. It affects cell proliferation. |
25 mg |
$258.00 |
| |
Induces apoptosis in MCF-7 human breast cancer cells. |
|
|
| |
Patel YC. Front Neuroendocrinol. 20:157-98 (1999). |
|
|
| |
Hocker M. Wiedenmann B. Ital J Gastroenteril. 31 Suppl 2:S139-42 (1999). |
|
|
| |
Thangaraju M, Sharma K, Liu D et al. Cancer Res. 59:1649-54 (1999). |
|
|
| |
|
|
|
| S5751 |
Somatostatin-25 |
0.5 mg |
$114.70 |
| |
C127H191N37O34S3 FW 2876.36 |
1 mg |
$195.30 |
| |
|
2.5 mg |
$344.10 |
| |
|
|
|
| S5750 |
Somatostatin-28 |
1 mg |
$466.70 |
| |
C137H207N41O39S3 FW 340.4 [75037-27-3] |
|
|
| |
|
|
|
| |
|
|
|
| S5752 |
Somatostatin-28 (1-12) |
1 mg |
$121.90 |
| |
C49H81N17O19S1 FW 1244.36 |
2 mg |
$207.90 |
| |
|
5 mg |
$365.60 |
| |
|
|
|
| S5753 |
Somatostatin-28 (1-14) |
1 mg |
$68.10 |
| |
C61H105N23O21S FW 1528.72 |
2 mg |
$207.90 |
| |
|
5 mg |
$365.60 |
| |
|
|
|
| S5754 |
Somatostatin Acetate |
Please inquire |
|
| |
C76H104N18O19S2 FW 1637.88 [378916-34-6] |
|
|
| |
|
|
|
| |
|
|
|
| S5868 |
Sorafenib |
25 mg |
$100.80 |
| |
C21H16ClF3N4O3 FW 464.82 [284461-73-0] |
100mg |
$324.80 |
| |
Sorafenib is a small molecular inhibitor of several protein kinases. Protein |
|
|
| |
kinases are overactive in many of the molecular pathways that cause cells to become cancerous. |
|
|
| |
Yang, F. Molecular Cancer Therapeutics (2008), 7(11), 3519-3526. |
|
|
| |
|
|
|
| S5976 |
Sotalol |
25 mg |
$44.80 |
| |
C12H20N2O3S FW 272.36 [3930-20-9] |
100mg |
$112.00 |
| |
Is a hypertension and cardiac arrhythmias. Inhibits the potassium channels in |
250mg |
$201.60 |
| |
the heart. The L-form of this compound is also a beta blocker. |
|
|
| |
de Graaf, C. Journal of Medicinal Chemistry (2008), 51(20), 6620. |
|
|
| |
|
|
|
| S6000 |
Sparfloxacin |
500mg |
$180.40 |
| |
C19H22F2N4O3 FW 392.40 [110871-86-8] |
1 g |
$295.10 |
| |
A fluoroquniolone antibacterial, acts on DNA gyrase. |
|
|
| |
Piddock LJ, Zhu M. Antimicrob Agents Chemother. 35:2423-7 (1991). |
|
|
| |
|
|
|
| |
|
|
|
| S6018 |
Spectinomycin hydrochloride |
5 g |
$49.70 |
| |
C14H24N2O7.2HCl.5H2O FW 495.25 [22189-32-8] |
25 g |
$158.70 |
| |
A broad-spectrum aminocyclitol antibiotic that is highly effective in the treatment of gonorrhea. |
|
|
| |
It has shown neuromuscular blocking activity by a predominant action on acetylcholine release. |
|
|
| |
Singh YN, Marshall IG, Harvey AL. Clin Exp Pharmacol Physiol. 6:159-65 (1979). |
|
|
| |
Holloway WJ. Med Clin North Am. 66:169-73 (1982). |
|
|
| |
|
|
|
| S6019 |
Speract |
1 mg |
$57.30 |
| |
C38H57N11O14 FW 891.94 |
2 mg |
$96.80 |
| |
A peptide associated with eggs of sea urchin, Lytechinus pictus. It has been |
5 mg |
$172.00 |
| |
shown ot bind to the plasma membrane receptor of spermatozoa and stimulate sperm respiration. |
|
|
| |
Repaske DR, Garbers DL. J Biol Chem. 258: 6025-9 (1983). |
|
|
| |
|
|
|
| S6129 |
D-Sphingosine |
5 mg |
$51.60 |
| |
C18H37NO2 FW 299.5 [123-78-4] |
25 mg |
$192.90 |
| |
It induces apoptosis by inhibiting protein kinase. It is also reported to cause inhibition |
|
|
| |
of adrenaline stimulated cyclic AMP accumulation, permeation of cells and making them leaky |
|
|
| |
to ATP, inhibition of adrenaline-stimulated adenylate cyclase inhibition of cyclic AMP. |
|
|
| |
Souktani R, Berdeaux A, Ghaleh B et al. Am J Physiol cell Physiol. 2797:C158-65 (2000). |
|
|
| |
Ju TZ, Chen HL, Gu JX, Qin H. Glycoconj J. 12:767-72 (1995). |
|
|
| |
Johnson JA, Clark RB. Biochem J. 268:507-11 (1990). |
|
|
| |
|
|
|
| S6131 |
Sphingosine, N, N-dimethyl |
5 mg |
$103.30 |
| |
C20H41NO2 FW 327.5 [119567-63-4] |
|
|
| |
A general modulator of protein kinases. Inhibites protein kinase C and stimulates src kinase; |
|
|
| |
induces apoptosis in human leukemia HL-60 cells. |
|
|
| |
Igarashi Y et al. J Biol Chem. 265:5385 (1990). |
|
|
| |
|
|
|
| S6130 |
Sphingosine 1-phosphate |
1 mg |
$216.90 |
| |
C18H38NO5P FW 379.47 [26993-30-6] |
|
|
| |
Ligand for a family of specific G-protein that regulates a wide variety of important cellular functions, |
|
|
| |
including vascular maturation, angiogenesis, apoptosis, cell growth, survival, cytoskeletal |
|
|
| |
rearrangement and cell motility by divergent pathways. |
|
|
| |
Spiegel S, Milstien S. Biochem Soc trans. 31:1216-9 (2003). |
|
|
| |
|
|
|
| S6134 |
Spinorphin, bovine |
5 mg |
$186.40 |
| |
C45H64N8O10 FW 877.06 |
10 mg |
$317.20 |
| |
An endogenous factor that exhibits inhibitory effects on enkephalin-degrading |
25 mg |
$559.10 |
| |
enzymes. |
|
|
| |
Yamamoto Y, Ono H, Ueda A, Shimamura M, Nishimura K, Hazato T. Curr Protein Pept Sci. 3: 587-99 (2002). |
|
|
| |
|
|
|
| S6232 |
Spiramycin |
1 g |
$43.90 |
| |
[8025-81-8] |
5 g |
$150.50 |
| |
A macrolide antibiotic. It has been shown to decrease the replication index of human |
|
|
| |
lymphocytes. |
|
|
| |
Rencuzogullari E, Ila HB, Topatkas M et al. Teratogenesis Carcinogenesis Mutagenesis. 22:51-58 (2002). |
|
|
| |
|
|
|
| S6234 |
Spiramycin Embonate |
1 g |
$57.80 |
| |
|
5 g |
$173.20 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| S6233 |
Spiramycin Hexanedioate |
1 g |
$56.40 |
| |
Spiramycin Adipate |
5 g |
$169.30 |
| |
|
|
|
| |
|
|
|
| |
|
|
|
| |
|
|
|
| S6168 |
Spirapril Hydrochloride |
100mg |
$65.00 |
| |
C22H30N2O5S2 FW 466.61 [83647-97-6] |
250mg |
$125.00 |
| |
Selectively suppresses the renin-angiotensin-aldosterone system; inhibits ACE, |
1 g |
$400.00 |
| |
prevents conversion of angiotensin I to angiotensin II; results in dilation of arterial and venous vessels. |
|
|
| |
Smith, Elizabeth M. Journal of Medicinal Chemistry (1989), 32(7), 1600-6. |
|
|
| |
|
|
|
| S6235 |
Spironolactone |
1 g |
$41.40 |
| |
C24H32O4S FW 416.57 [52-01-7] |
5 g |
$165.60 |
| |
An aldosterone antagonist. It directly interferes with the biosynthesis of |
|
|
| |
aldosterone in bovine and certain human adrenal cortical tissue. |
|
|
| |
Cheng SC, Suzuki K, Sadee W et al. Endocrinology. 99:1097-106 (1976). |
|
|
| |
Bendtzen K, Hansen PR, Rieneck K. Clin Exp Immunol. 134:151-8 (2003). |
|
|
| |
|
|
|
| S7080 |
SR Poly Caspases Assay Kit |
25Tests |
$199.50 |
| |
SR-VAD-FMK |
100 Tests |
$488.00 |
| |
|
|
|
| S7081 |
SR Caspases 3 and 7 Assay Kit |
25 Tests |
$224.60 |
| |
SR-DEVD-FMK |
100 Tests |
$538.20 |
| |
|
|
|
| S7082 |
SR Caspase 9 Assay Kit |
25 Tests |
$224.60 |
| |
SR-LEHD-FMK |
100 Tests |
$538.20 |
| |
|
|
|
| S7083 |
SR-101-Phe-CMK FLISPTM Assay Kit |
25 Tests |
$161.80 |
| |
SFCK |
100 Tests |
$462.90 |
| |
|
|
|
| S7084 |
SR-101-Leu-CMK FLISPTM Assay Kit |
25Tests |
$161.80 |
| |
SLCK |
100Tests |
$462.90 |
| |
|
|
|
| S7600 |
Staurosporine |
1 mg |
$344.40 |
| |
C28H26N4O3 FW 466.5 [62996-74-1] |
5 mg |
$1,344.00 |
| |
A protein kinase C inhibitor that induces apoptosis in many cell types. Experimental results |
|
|
| |
obtained in a cell-free assay suggest that cytoplasmic proteins directly modulated by staurosporine |
|
|
| |
may be involved in signaling the induction of DNA fragmentation and apoptosis. |
|
|
| |
Romanova D, Novotny L, Sedlak J et al. Neoplasma. 45: 204-9. (1998). |
|
|
| |
Zhang H, Hoang T, Saeed B, Ng SC. Prostate. 29:69-76 (1996). |
|
|
| |
Bertrand R, Solary E, O'connor P et al. Exp Cel Res. 211:314-21 (1994). |
|
|
| |
|
|
|
| S7603 |
Stavudine |
100 mg |
$50.40 |
| |
C10H12N2O4 FW 224.21 [3056-17-5] |
250 mg |
$112.00 |
| |
Is a nucleoside analog reverse transcriptase inhibitor active against HIV. |
1 g |
$280.00 |
| |
Stavudine triposphate inhibits HIV reverse transcriptase and terminates DNA synthesis. |
|
|
| |
Liu, Lian Jin. Bulletin of the Korean Chemical Society (2008), 29(9), 1723-1728. |
|
|
| |
Byakika-Kibwika, P. Journal of Antimicrobial Chemotherapy (2008), 62(5), 1113-1117. |
|
|
| |
|
|
|
| S7717 |
Sterigmatocystin |
1 mg |
$39.20 |
| |
C18H12O6 FW 324.28 [10048-13-2] |
5 mg |
$147.80 |
| |
Mycotoxin produced by strains of the common molds. Induces sister chromatid |
10 mg |
$266.60 |
| |
exchanges in bone marrow cells of mice. It causes necrosis of the liver and kidney |
|
|
| |
and has an inhibitory effect on orotic acid incorporation into nuclear RNA. |
|
|
| |
Curry PT et al. Mutat. Res. 137:111 (1984). |
|
|
| |
Terao K Acta Pathol. Jpn. 23:647-53 (1973). |
|
|
| |
Nel W, Pretorius HE Biochem. Pharmacol. 19:957-9 (1970). |
|
|
| |
|
|
|
| S7769 |
Streptomycin sulfate |
25 g |
$22.20 |
| |
(C21H39N7O12)2.3H2SO4 FW 1457.39 [3810-74-0] |
50 g |
$37.30 |
| |
An aminosugar containing antibiotic from Streptomyces griseus. It was the |
100 g |
$63.50 |
| |
first antibiotic used for the treatment of tuberculosis. Its mechanism of action is the |
|
|
| |
inhibition of ribosome protein synthesis. |
|
|
| |
Kornder JD. Med Hypotheses. 58:34-46 (2002). |
|
|
| |
|
|
|
| S7870 |
Streptozocin |
50 mg |
$22.60 |
| |
Streptozotocin; N-(methyl-nitrosocarbamoyl)-a-D-glucosamine |
100 mg |
$35.20 |
| |
C8H15N3O7 FW 265.22 [18883-66-4] |
500 mg |
$119.20 |
| |
An antitumor agent, used primarily for the treatment of pancreatic cancers. |
|
|
| |
DuPriest RW Jr., Huntington MC, Massey WH et al. Cancer. 35:358-367 (1975). |
|
|
| |
|
|
|
| S7871 |
Stresscopin, human |
0.5 mg |
$164.90 |
| |
C195H326N56O53S2 FW 4367.24 |
1 mg |
$279.60 |
| |
A neuropeptide with high affinity for type 2 corticotropin-releasing factor |
2.5 mg |
$494.60 |
| |
receptor. It is a potent regulator of cardiovascular functions. |
|
|
| |
Nazarloo HP, Buttrick PM, Saadat H, Dunn AJ. Curr Protein Pept Sci. 7: 229-39 (2006). |
|
|
| |
|
|
|
| S7872 |
Stresscopin-Related Peptide, human |
0.5 mg |
$179.20 |
| |
C205H358N68O57 FW 4687.56 |
1 mg |
$304.60 |
| |
A type 2 corticotropin-releasing factor receptor agonist. |
2.5 mg |
$537.60 |
| |
Gardiner SM, March JE, Kemp PA, Bennett T. J Pharmacol Exp Ther. 321: 221-6 (2007). |
|
|
| |
|
|
|
| S7970 |
Strontium Ranelate |
1 g |
$50.00 |
| |
C12H10N2O8S FW 342.28 [135459-87-9] |
5 g |
$200.00 |
| |
A medication for osteoporosis. It is unusual in the sense that it both increases |
|
|
| |
deposition of new bone osteoblasts and reduces the resorption of bone by osteoclasts. |
|
|
| |
It is therefore promoted as a "dual action bone agent" (DABA). |
|
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| |
Fuchs, R. K. Osteoporosis International (2008), 19(9), 1331-1341. |
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| S8005 |
Substance P |
5 mg |
$64.50 |
| |
C63H98N18O13S1 FW 1347.66 |
10 mg |
$109.30 |
| |
A neurotransmitter peptide that is distributed in sensory nerve fibers, bone, |
25 mg |
$193.50 |
| |
and bone-related tissue. It is involved in pain signal transmission and modulates the |
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| |
function of inflammatory and immune responses. |
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| |
Michalski CW, Autschbach F, and Selvaggi F et. al. Am J Surg. 193: 476-81 (2007). |
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Corcoran KE, Patel N, Rameshwar P. J Immunol. 178: 2075-82 (2007). |
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Monnikes H, van der Voort IR, and Wollenberg B et. al. Digestion 71:111-23 (2005). |
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| S8006 |
Substance P (1-4) |
1 mg |
$35.80 |
| |
C22H40N8O5 FW 496.6 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
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| S8007 |
Substance P (1-7) |
1 mg |
$35.80 |
| |
C41H65N13O10 FW 900.06 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
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|
| S8008 |
Substance P (1-9) |
1 mg |
$35.80 |
| |
C52H77N15O12 FW 900.06 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
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| S8009 |
Substance P (7-11) |
1 mg |
$35.80 |
| |
C31H44N6O5S1 FW 612.8 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
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|
| S8010 |
[Nle11] Substance P |
1 mg |
$35.80 |
| |
C64H100N18O13 FW 1329.62 |
2 mg |
$60.90 |
| |
|
5 mg |
$107.50 |
| |
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|
| S8011 |
[Pro9] Substance P |
0.5 mg |
$35.80 |
| |
C66H102N18O13S1 FW 1387.73 |
1 mg |
$60.90 |
| |
|
2.5 mg |
$107.50 |
| |
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| S8012 |
[Sar9] Substance P |
1 mg |
$50.20 |
| |
C64H100N18O13S FW 1361.61 |
2 mg |
$86.00 |
| |
|
5 mg |
$150.50 |
| |
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| S8013 |
[Tyr8] Substance P |
1 mg |
$57.30 |
| |
C63H98N18O14S1 FW 1363.66 |
2 mg |
$96.80 |
| |
|
5 mg |
$172.00 |
| |
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| S8014 |
Substance P, Free Acid |
5 mg |
$64.50 |
| |
C63H97N17O14S FW 1348.65 |
10 mg |
$109.30 |
| |
|
25 mg |
$193.50 |
| |
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| S7908 |
Suc-APA-pNA |
100 mg |
$68.10 |
| |
C21H27N5O8 FW 477.5 |
1g |
$421.10 |
| |
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| S7909 |
Suc-LEPF-pNA |
1 mg |
$71.70 |
| |
C35H44N6O11 FW 724.7 |
10 mg |
$286.70 |
| |
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| S8110 |
Sucralfate |
1 g |
$39.20 |
| |
Sucrose Octasulfate-Aluminum Complex |
5 g |
$134.40 |
| |
C12H30Al8O51S8. [Al(OH)3]x.(H2O)y x=8 to 10; y=22 to 3 [54182-58-0] |
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| |
Is an oral gastrointestinal medicationi primarily used for the treatment of |
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| |
gastroesophageal reflux disease and stress orders. The mechanism of action involves |
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| |
the complex binding to hydrochloric acid in the stomach and forms a paste-like . |
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| |
substance which provides protection to the stomach lining |
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| |
Du, Y. Digestive Diseases and Sciences (2008), 53(11), 2886-2895. |
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| S7910 |
Suc-RGPF-pNA |
1 mg |
$71.70 |
| |
C32H41N9O9 FW 695.7 |
10 mg |
$286.70 |
| |
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| |
Sucrose Octasulfate-Aluminum Complex (See Sucralfate) |
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| |
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| S7911 |
Suc-SDPF-pNA |
1 mg |
$71.70 |
| |
C31H36N6O12 FW 684.6 |
10 mg |
$286.70 |
| |
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| |
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| S8244 |
Sulbactam |
500 mg |
$73.90 |
| |
C8H11NO5S FW 233.24 [68373-14-8] |
1 g |
$127.90 |
| |
A beta-lactamase inhibitor that has similar characteristics as ampicillin. |
5 g |
$491.80 |
| |
Often used in combination with other antibiotics. |
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| |
Wexler HM, Molitoris E, Finegold SM. Antimicrob Agents Chemother. 35:1219-24 (1991). |
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| |
Foulds G, Stankewich JP, Marshall DC et al. Antimicrob Agents Chemother. 2:692-9 (1983). |
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| S8243 |
Sulbactam sodium salt |
500 mg |
$69.00 |
| |
C8H10NNaO5S FW 255.22 [69388-84-7] |
1 g |
$125.40 |
| |
|
5 g |
$489.20 |
| |
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| |
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| S8245 |
Sulfadiazine |
50 g |
$18.30 |
| |
C10H10N4O2S FW 250.28 [68-35-9] |
100 g |
$30.50 |
| |
Anti-microbial agent. Its chlorambucil derivative is found to be a potent |
500 g |
$121.50 |
| |
antitumor agent. |
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| |
Huang Z, Yang G, Lin Z, Huang J. Bioorg Med Chem Lett 11:1099-103 (2001). |
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| S8246 |
Sulfadimethoxine |
10 g |
$41.10 |
| |
C12H14N4O4S FW 310.33 [122-11-2] |
25 g |
$73.90 |
| |
A sulfonamide antibiotic. |
100 g |
$205.10 |
| |
Fish JG, Morgan DW, Horton CR. Vet Med Small Anim Clin. 60:1201-3 (1965). |
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| S8144 |
Sulfadoxine |
10 g |
$48.40 |
| |
C12H14N4O4S FW 310.33 [2447-57-6] |
25 g |
$103.50 |
| |
An antibacterial agent. |
100 g |
$276.00 |
| |
Bohni E, Fust B, Rieder J. Chemotherapy. 14:195-226 (1969). |
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| S8248 |
Sulfamethoxazole |
10 g |
$25.10 |
| |
C10H11N3O3S FW 253.28 [723-46-6] |
25 g |
$43.90 |
| |
An antimicrobial. Used in conjunction with trimethoprim as the first-line |
100 g |
$125.40 |
| |
treatment for P. carinii pneumonia. |
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| |
Kovacs JA, Gill VJ, Meshnick S et al. JAMA. 286: 2450-2460 (2001). |
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| |
Rodriguez MR, Pizzorno MT, Albonico SM. J Pharm Sci. 66:121-123 (1977). |
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| S8247 |
Sulfasalazine |
10 g |
$45.60 |
| |
C18H14N4O5S FW 398.39 [599-79-1] |
50 g |
$136.60 |
| |
It is a disease-modifying antirheumatic drug (DMARD) that inhibits extracelluar |
100 g |
$220.20 |
| |
release of proinflammatory secretory phospholipase A2. It was found to induce |
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| |
neutrophil apoptosis and regulate human B cell function. |
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| |
Pruzanski W, Stefanski E, Vadas P, Ramamurthy NS. Biochem Pharm. 53:1901-1907 (1997). |
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| |
Akahoshi T, Namai R, Sekiyama N et al. J Leuk Biol. 62:817-826 (1997). |
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| |
Hirohata S, Ohshima N, Yanagida T, Aramaki K. Int Immunopharm. 2:631-640 (2002). |
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| S8251 |
Sulfluramid |
500 mg |
$47.70 |
| |
C10H6F17NO2S 527.20 [4151-50-2] |
1 g |
$69.00 |
| |
A delayed-action insecticide. |
5 g |
$276.00 |
| |
Reid BL, Bennett GW, Barcay SJ. J Econ Entomol. 83:148-152 (1990). |
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| S8044 |
R,S-Sulforaphane |
25 mg |
$109.00 |
| |
1-Isothiocyanato-4-(methylsulfinyl)-butane, D,L-sulforaphane |
50 mg |
$181.20 |
| |
C6H11NOS2 FW 177.29 b.p. 125-1350C (0.01mm) [4478-93-7] |
100 mg |
$326.10 |
| |
d=1.183 |
500 mg |
$1,099.50 |
| |
Sulforaphane is a Phase II enzyme inducer present in brocolli. It was found to |
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| |
inhibit chemically induced mammary tumor formation in rats. R,S-sulforaphane is a synthetic compound. |
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| |
Zhang Y, Talalay P, Cho CG, Posner GH. Proc Natl Acad Sci USA. 89:2399-2403 (1992). |
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| |
Zhang Y, Kensler TW, Cho CG et al. Proc Natl Acad Sci USA. 91:3147-3150 (1994). |
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| S8045 |
S-Sulforaphane |
5 mg |
$129.10 |
| |
(+)1-Isothiocyanato-4S-(methylsulfinyl)-butane, D-sulforaphane |
10 mg |
$220.20 |
| |
C6H11NOS2 FW 177.29 b.p. 125-1350C (0.01 mm) |
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| |
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| S8046 |
R-Sulforaphane |
10 mg |
$157.20 |
| |
(-)1-Isothiocyanato-4R-(methylsulfinyl)-butane, L-sulforaphane |
25 mg |
$314.30 |
| |
C6H11NOS2 FW 177.29 [142825-10-3] |
50 mg |
$594.50 |
| |
[a]22D -73.1 +/-0/40 (c=1, CHCl3) b.p. 125-1350C (0.01mm) |
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| |
Chiral natural product from broccoli. Inducer of phase II enzymes. |
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| |
Zhang Y, Talalay P, Cho C-G, Posner GH. Proc Natl Acad Sci USA. 89:2399-2403 (1992). |
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| S8049 |
S-Sulforaphene |
10 mg |
$157.20 |
| |
(-)4-Isothiocyanato-4S-(methylsulfinyl)-1-butene, L-sulforaphene |
25 mg |
$314.30 |
| |
C6H9NOS2 FW 175.27 [592-95-0] [a]D-99.60 |
50 mg |
$594.50 |
| |
Chiral natural product from radish. |
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| |
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| S8145 |
Sulindac |
5 g |
$36.20 |
| |
C20H17FO3S FW 356.42 [38194-50-2] |
25 g |
$123.00 |
| |
Non-steroidal anti-inflammatory agent. Has undergone clinical |
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| |
trials as a chemopreventive. |
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| |
Kelloff GJ, Boone CW, Crowell JA et al. Cancer Epidemiol, Biomarkers Prev. 3:85-98 (1994). |
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| S8147 |
Sulindac sulfide |
25 mg |
$73.90 |
| |
C20H17FO2S FW 340.4 [32004-67-4] |
100 mg |
$205.10 |
| |
An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces |
500 mg |
$655.80 |
| |
apoptosis by a cyclooxygenase-independent mechanism. |
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| |
Meade EA, Smith WL, DeWitt DL. J Biol Chem. 268:6610-6614 (1993). |
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| |
Piazza GA, Rahm AL, Krutzsch et al. Cancer Res. 55:3110-3116 (1995). |
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| S8146 |
Sulindac sulfone |
50 mg |
$73.90 |
| |
C20H17FO4S FW 372.41 [59864-04-9] |
250 mg |
$213.00 |
| |
A metabolite of Sulindac, found to inhibit rat colon and mammary |
500 mg |
$344.40 |
| |
carcinogenesis without reducing prostaglandin levels. |
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| |
Piazza GA, Alberts DS, Hixson LJ et al. Cancer Res. 57:2909-2915 (1997). |
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| |
Thompson HJ, Jiang C, Lu J et al. Cancer Res. 57:267-271 (1997). |
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| |
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| S8151 |
Sumatriptan Succinate |
100 mg |
$84.00 |
| |
C14H21N3O2S.C4H6O4 FW413.49 [103628-48-4] |
250 mg |
$162.40 |
| |
Antimigrane. |
1 g |
$504.00 |
| |
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| S8253 |
Sunitinib Malate |
25 mg |
$89.60 |
| |
Sutent |
100 mg |
$280.00 |
| |
C26H33FN4O7 FW 532.56 [341031-54-7] |
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| |
Inhibitor of VEGF and PDGF tyrosine kinase. |
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| |
Sosman JA, Puzanov I, Atkins MB Clin. Cancer Res. 13:764s-769s (2007). |
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| |
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| S8169 |
Suramin hexasodium salt |
50 mg |
$121.20 |
| |
C51H34N6O23S6Na6 FW 1429.19 [129-46-4] |
250 mg |
$409.70 |
| |
An antitumor and antiparasitic compound. Uncouples G-proteins from receptors. |
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| |
A potent inhibitor of melanoma heparanase and tumor cell metastasis. |
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| |
Huang RR, Dehaven RN, Cheung AH et al. Mol Pharmacol. 37:304-310 (1990). |
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| |
Nakajima M, DeChavigny A, Johnson CE et al. J BiolChem. 266:9661-9666 (1991). |
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| S9753 |
Synephrine |
1 g |
$30.90 |
| |
1-[4-Hydroxyphenyl]-2-[methyl-amino]ethanol |
5 g |
$112.10 |
| |
C9H13NO2 FW 167.21 [94-07-5] |
10 g |
$172.10 |
| |
A biogenic amine present in herbal products and citrus juices. It has antidepressant-like effects |
|
|
| |
by stimulating a1-adrenoceptors in mice. |
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| |
Hurlbut JA, Carr JR, Singleton ER et al. J Aoac Int. 81:1121-1127 (1998). |
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| |
Cancalon PF. J Aoac Int. 82:95-106 (1999). |
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| |
Song DK, Suh HW, Jung JS et al. Neurosci Lett. 214:107-110 (1996). |
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| |
Brown CM, McGrath JC, Midgley JM. Br J Pharmacol. 3:417-429 (1988). |
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| S9754 |
Syntide 2 |
1 mg |
$71.70 |
| |
C68H122N20O18 FW 1507.85 |
2 mg |
$121.90 |
| |
A synthetic substrate for Ca2+ calmodulin-dependent protein kinase II |
5 mg |
$215.00 |
| |
Colavizza M, Hervagault JF. Biochimie. 84: 605-10 (2002). |
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| |
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| S9775 |
Systemin |
0.5 mg |
$64.50 |
| |
C85H144N26O28S FW 2010.32 |
1 mg |
$109.30 |
| |
A polypeptide induces the expression of proteinase inhibitor gene in (tomato). |
2.5 mg |
$193.50 |
| |
Wasternack C, Stenzel I and Hause B et. al. J Plant Physiol. 163: 297-306 (2006). |
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