| S0006 |
S6-1 |
|
|
|
A sythetic octapeptide that represents the
phosphorylated region of the S6 protein.
Hecht LB, Straus DS. Endocrinology. 119: 470-80 (1986). |
1 mg
2 mg
5 mg |
$44.80
$76.80
$134.40 |
| S0132 |
Saikosaponin A |
|
|
|
The saikosaponins have potent anti-inflammatory
activity on mouse ear edema induced by the tumor promoter, phorbol myristate
acetate. In cell culture studies, they have been found to induce
differentiation without growth inhibition and apoptosis in B16 melanoma
cells.
Zong Z, Fujikawa-Yamamoto K, Ota T et al. Cell Struct Funct. 23:265-272
(1998).
Bermejo BP, Abad Martinez MJ, Silvan Sen AM et al. Life Sci. 63:1147-1156
(1998).
Zong Z, Fujikawa-Yamamoto K, Tanino M et al. Biochem Biophys
Res Commun. 219:480-485 (1996).
Ohtsuka M, Fukuda K, Yano H, Kohiro M. Jpn J Cancer Res. 86:1131-1135
(1995).
Qian L, Murakami T, Kimura Y et al. Pathol Int. 45:207-214 (1995). |
1 mg
5 mg |
$168.40
$658.70 |
| S0032 |
Saikosaponin B1 |
|
|
|
Saidosaponin B1 induces PGE2 release in C6 rat
glioma cells. In cultured fibroblasts saikosaponin B1 suppresses the
blockage of signal transduction after binding of EGF resulting in growth
stimulation.
Kyo R, Nakahata N, Kodama Y et al. Biol Pharm Bull.
22:1385-7 (1999).
Nishiyama T, Horii I, Nakayama Y et al. Matrix. 10:412-9 (1990). |
1 mg
5 mg |
$61.60
$228.00 |
| S0033 |
Saikosaponin B2 |
|
|
|
Saikosaponin B2 inhibits the proliferation of B16
melanoma cells in culture by induction of apoptosis. The inhibition is a
result of G1 phase accumulation.
Zong Z, Fujikawa-Yamamoto K, Tanino M, et al. Biochem Biophys Res Commun.
219:480-5 (1996). |
1 mg
5 mg |
$61.60
$228.00 |
| S0133 |
Saikosaponin C |
|
|
|
Saikosaponin C was found to have inhibiting activity
in hepatitis B virus DNA replicaiton.
Chiang LC, Ng LT, Liu LT et al. Planta Med. 69:705-9 (2003). |
1 mg
5 mg |
$168.40
$658.70 |
| S0134 |
Saikosaponin D |
|
|
|
Saikosaponin D was found to stimulate
corticotropin-releasing factor (CRF) gene expression and CRF release. It
also increases adrenocorticotropin release.
Dobashi I, Tozawa F, Horiba N et al. Neurosci Lett. 197:235-238 (1995). |
1 mg
5 mg |
$168.40
$658.70 |
| S0044 |
Salbutamol free base |
|
|
|
Albuterol
A beta-adrenoceptor agonist.
Church MK, Hiroi J. Br J Pharmacol. 90:421-9 (1987). |
25 mg
50 mg
100 mg
500 mg |
$29.40
$51.30
$87.90
$322.00 |
| S0045 |
Salbutamol sulfate |
|
|
|
Albuterol sulfate
A beta-adrenoceptor agonist.
Church MK, Hiroi J. Br J Pharmacol. 90:421-9 (1987). |
25 mg
50 mg
100 mg
500 mg |
$29.40
$51.30
$84.90
$307.50 |
| S0048 |
Salicin |
|
|
|
An analgesic and antipyretic. Reported to have
antileukemic activity.
Smith ID, Temple DM, Shearman RP. Prostaglandins. 10:41-57 (1975).
El-Shemy HA, Aboul-Enein AM, Aboul-Enein MI et al. J Biochem Mol Biol. 36:
387-389 (2003). |
5 g
25 g |
$22.40
$95.20 |
| S0049 |
Salmon Calcitonin Acetate |
|
|
|
Salmon calcitonin acetate positively influences bone
mass density due to its inhibiting effect on osteoclast activity. For the
treatment of osteoporosis, paget’s disease, hypercalcemia, reflex sympathetic
dystrophy (algodistrophy or Sudeck’s disease).
Kopaliani M. Georgian Med News. 121: 38-42 (2005). |
|
Please inquire |
| S0046 |
Salsolidine |
|
|
|
A tetrahydroisoquinolone that is a steroselective
competitive inhibitor of the enzyme monoamine oxidase. It is also a
competitive inhibitor of catechol-O-methyltransferase.
Bembenek ME, Abell CW, Chrisey LA et al. J Med Chem. 33:147-52 (1990).
Dostert P, Strolin Benedetti M, Dordain G. J Neural Transm. 74:61-74
(1988).
Sanft K, Thomas H. Z Naturforsch [C]. 44:173-6 (1989). |
25 mg
100 mg |
$37.00
$104.80 |
| S0047 |
Salsoline |
|
|
|
Salsoline, a tetrahydroisoquinolone, is an active
metabolite of dopamine. It inhibits cholinesterase activity.
Sallstrom Baum S, Hill R, Kiianmaa K, Rommelspacher H. Alcohol. 1:165-9
(1999).
Maizel EB, Rozengart EV, Khakimov IuP et al. Biokhimiia.
43:1150-6 (1978). |
25 mg
100 mg |
$37.00
$104.80 |
| S0200 |
SAMs Peptide |
|
|
|
A synthetic peptide often used to determine
AMP-activated protein kinase activity.
Kishimoto A, Ogura T, Esumi H. Mol Biotechnol. 32: 17-21 (2006). |
0.5 mg
1 mg
2.5 mg |
$70.40
$120.00
$211.20 |
| S0053 |
α-Santonin |
|
|
|
An anthelmintic shown to have antiinflammatory,
antipyretic and analgesic activity comparable to those of the NSAID,
diclofenac sodium.
Al-Harbi MM, Ourreshi S, Ahmed MM et al. Japanese J Pharmacol. 64:135-139
(1994). |
5 g
10 g
25 g |
$20.40
$29.80
$67.80 |
| S0170 |
Sarafloxacin Hydrochloride |
|
|
|
A fluoroquinolone antibacterial agent found to be
effective against Mycobacterium tuberculosis.
Chu DT, Fernandes PB, Claiborne AK et al. J Med Chem. 28:1558-64
(1985).
Berlin OG, Young LS, Bruckner DA. J Antimicrob Chemother. 19:611-5 (1987). |
5 g
10 g
25 g |
$59.20
$92.40
$184.80 |
| S0171 |
Sarafotoxin 6c |
|
|
|
A selective endothelin subtype B receptor agonist
that induces muscle contractions.
Fellner SK, Arendshorst W. Am J Physiol Renal Physiol. 292: F175-84 (2007). |
0.5 mg
1 mg
2.5 mg |
$198.40
$337.60
$595.20 |
| S0368 |
Sarcophine |
|
|
|
It is a cembranoid marine natural product that is
reposted to possess cancer chemopreventive properties. Sarcophine was found
to be an effective inhibitor of JB6 cell transformation.
Sawant, S. S.; Youssef, D. T. A.; Reiland, J.; Ferniz, M.; Marchetti,
D.; El Sayed, M. D. J. Nat. Prod. 69:1010-1013 (2006).
El Sayed, K. A.; Hamann, M. T.; Waddling, C. A.; Jensen, C.; Lee, S. K.;
Dunstan, C. A.; Pezzuto, J. M. J. Org. Chem.63:7449-7455 (1998).
Katsuyama, I.; Fahmy, H.; Zjawiony, J. K.;
Khalifa, S. I.; Kilada, R. W.; Konoshima, T.; Takasaki, M.; Tokuda, H. J.
Nat. Prod. 65:1809-1814 (2002).
Sawant, S. S.; Sylvester, P. W.; Avery, M. A.; Desai, P.; Youssef, D. T. A.;
El Sayed, K. A. J. Nat. Prod. 67:2017-2023 (2004). |
10 mg |
$125.30 |
|
2-epi-16-deoxysarcophine |
|
|
|
See Deoxysarcophine, 2-epi-16- |
|
|
| S0278 |
Satraplatin |
|
|
|
An orally active novel platinum IV anticancer agent.
It shows promise against lung cancer and ovarian cancer.
Bengtson EM, Rigas JR. Drugs. 58 Suppl 3:57-69 (1999).
Piccart MJ, Lamb H. Vermorken JB. Ann Oncol. 12:1195-203 (2001). |
5 mg
10 mg
50 mg |
$123.20
$207.00
$800.80 |
| S0381 |
Sauvagine |
|
|
|
A frog skin peptide that has been shown to inhibit
production of prolactin.
Falaschi P, D'Urso R, Negri L et al. Endicrinology. 111: 693-695 (1982). |
0.5 mg
1 mg
2.5 mg |
$198.40
$337.60
$595.20 |
| S0830 |
R(+) Schisandrin A |
|
|
|
R(+) Schizandrin A; R(+) deoxyschisandrin A; R(+)
deoxyschizandrin A |
5 mg
10 mg |
$71.50
$117.10 |
| S0831 |
S(-) Schisandrin B |
|
|
|
S(-) Schizandrin B; S(-)-schisandrin; S(-) wuwei zi
su; gomisin N
Schisandrin B shows antioxidant activity which may be responsible for its
hepatic protecting activity. It also increases glutathione level and
Dt-diaphorase enzyme activity.
Lee IS, Lee HK, Dat NT. Planta Med.
69:63-4 (2003).
Chen DF, Zhang SX, Xie L et al. Bioorg Med Chem. 5:1715-23 (1997).
Ip SP, Yiu HY, Ko KM. Mol Cell Biochem. 208:151-5 (2000). |
5 mg
10 mg |
$71.50
$117.10 |
| S0930 |
Schisantherin A |
|
|
|
Schizantherin A; Gomisin C; Wuweizi ester A
A lignan from Schisandra chinensis. It has shown a positive effect in
lowering the serum glutamic-pyruvic transaminase level of patients suffering
from chronic viral hepatitis.
Liu CS, Fang SD, Huang MF. Sci Sin.
21:483-502 (1978). |
5 mg
10 mg |
$71.50
$117.10 |
| S1058 |
Scopolamine N-butylbromide |
|
|
|
Hyoscine butylbromide
An antispasmodic agent.
Ayre-Smith G. Acta Radiol Diagn (Stockh). 17:701-13 (1976). |
1 g
5 g |
$29.60
$76.40 |
| S1059 |
Scopolamine Hydrobromide |
|
|
|
An anticholinergic agent.
De Souza H, Palermo-Neto J. Gen Pharmacol. 16:533-6 (1985). |
1 g
5 g
25 g |
$44.80
$145.60
$492.80 |
| S1060 |
SCPA |
|
|
|
Small cardioactive peptide A. A neuropeptide that
modulates neuromuscular synapsis in Aplysia.
Fox LE, Lloyd PE. J Neurophysiol. 83:1567-79 (2000). |
1 mg
2 mg
5 mg |
$38.40
$65.60
$115.20 |
| S1061 |
SCPB |
|
|
|
Small cardioactive peptide B
An antagonistic inhibitor of cAMP-dependent Cl- current in sensory neurons
of Aplysia via activation of protein kinase A.
Buttner N, Siegelbaum SA. J Neurophysiol. 90: 586-98 (2003). |
1 mg
2 mg
5 mg |
$38.40
$65.60
$115.20 |
| S1343 |
Ac-S-D-K-P |
|
|
|
A synthetic hemopeptide shown to inhibit
hematopoietic proliferation in stem cells.
Dai G, Huang C, Li Y, Pi YH, Wang BH. Cell Biol Int. 30: 514-20 (2006). |
5 mg
10 mg
25 mg |
$76.80
$131.20
$230.40 |
| S1810 |
Secnidazole |
|
|
|
An antimicrobial used as amoebecide and
trichomonacide.
Benazet F, Guillaume L. Bull Soc Pathol Exot Filiales. 69:309-19
(1976).
Gillis JC, Wiseman LR. Drugs. 51:621-38 (1996). |
5 g
10 g
25 g |
$37.00
$55.50
$92.40 |
| S1604 |
Secretin Acetate |
|
|
|
|
|
Please inquire |
| S1605 |
Secretin, human |
|
|
|
Secretin is a polypeptide gastrointestinal hormone.
It stimulates exocrine pancreatic secretion.
Chey WY, Chang TM. J Gastroenterol. 38:1025-35 (2003).
Konturek SJ, Thor P, Dembinski A et al. Gastroenterology. 68:1527-35
(1975). |
1 mg
2 mg
5 mg |
$121.60
$206.40
$364.80 |
| S1606 |
Secretin, porcine |
|
|
|
|
5 mg
10 mg
25 mg |
$364.80
$620.80
$1,094.40 |
| S1607 |
Secretin, rat |
|
|
|
|
0.5 mg
1 mg
2.5 mg |
$72.00
$121.60
$214.40 |
| S1609 |
Securinine |
|
|
|
A g-aminobutyric acid (GABA) receptor antagonist.
Recently, it was found to induce apoptosis in human leukemia HL-60
cells.
Beutler JA, Karbon EW, Brubaker AN et al. Brain Res. 330:135-40 (1985).
Dong NZ, Gu ZL, Chou WH, Kwok CY. Chung Kuo Yao
Li Hsueh Pao. 20:267-70 (1999). |
500 mg
1 g |
$71.50
$104.80 |
| S1612 |
Sedanolide |
|
|
| -20 oC |
(3-Butyl-3a,4,5,6-tetrahydro-1(3H)-isobenzofuranone)
Natural product isolated from celery seed oil. Inducer of glutathione
S-transferase enzyme system. Inhibitor of chemically induced
carcinogenesis.
Zheng G-q, Kenney, PM, Lam LKT. Nutr. Cancer. 19:77-86
(1993). |
100 mg
500 mg
1 g |
$98.70
$321.30
$567.40 |
| S1843 |
L-Selectin |
|
|
|
A glycoprotein receptor that mediates lymphocyte
rolling in high endothlial venules.
Sperandio M, Frommhold D, Babushkina I and Ellies LG et. al. Eur J Immunol.
36: 3207-15 (2006). |
1 mg
2 mg
5 mg |
$112.70
$192.00
$338.00 |
| S1845 |
L-(+)-Selenomethionine |
|
|
| -20 oC |
Inhibitor of 2-acetylaminofluorene-induced
hepatocarcinogenesis.
Mukherjee B, Ghosh S, Chatterjee M. J Exp Ther Oncol. 14:209-217 (1996). |
10 mg
25 mg
100 mg |
$17.20
$35.40
$117.40 |
| S1848 |
Se-methylseleno-L-cysteine |
|
|
|
Inhibitor of DMBA-induced mammary tumors.
Ip C, Ganther HE. Carcinogenesis. 7:1167-1170 (1992). |
100 mg
250 mg |
$74.30
$148.60 |
| S1969 |
Sermorelin Acetate |
|
|
|
Secretin stimulates the secretion of bicarbonate by
the pancreas and inhibits the production of gastrin and acid production in
the stomach. It also potentiates the release of digestive enzymes from the
pancreas triggered by cholecystokinin. Diagnosis of pancreatic dysfunctionand
the presence of a gastrinoma treating. For the treatment of autism-not yet
approved applications. |
|
Please inquire |
| S1970 |
Serum Thymic Factor |
|
|
|
A thymic peptide hormone that induces the formation
of E rosettes.
Incefy GS, Mertelsmann R, Yata K, Dardenne M, Bach JF, Good RA.
Haematologia (Budap). 13: 203-11 (1980). |
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| S2044 |
S-F-L-L-R |
|
|
|
A protease-activated receptor 1 agonist peptide that
exhibits cell proliferation effects.
Hirota Y, Osuga Y, Hirata T and Yoshino O et. al. J Clin Endocrinol Metab.
90: 3673-9 (2005). |
1 mg
2 mg
5 mg |
$51.20
$86.40
$153.60 |
| S3033 |
Shikimic acid |
|
|
|
An antimicrobial agent with antagonistic effects.
It inhibits rapamycin biosynthesis in Streptomyces hygroscopicus.
Ma Y, Xu QP, Sun JN et al. Chung Kuo Yao Li Hsueh Pao. 20:701-4 (1999).
Fang A, Demain AL. Folia Microbiol (Praha). 40:607-10
(1995). |
1 g
5 g |
$55.50
$215.60 |
| S3343 |
Silybin |
|
|
| 0 oC |
The major component of silymarin, a group of
polyphenolic flavonoids derived from milk thistle (Silybum marianum) that has
anti-inflammatory, cytoprotective and anti-carcinogenic effects . It is
reported that Silybin has protective effect against skin cancer and inhibits
mitogen-activated protein kinase.
Manna SK, Mukhopadhyay A, Van NT, Aggarwal BB. J Immunol. 163:6800-9
(1999).
Zi X, Agarwal R, Biochem Biophys Res Commun. 263:528-36 (1999). |
500 mg
1 g
5 g |
$23.20
$38.50
$153.70 |
| S3345 |
Silymarin |
|
|
| -20 oC |
Flavanoid antioxidant isolated from milk thistle
that is effective chemopreventive agents.
Steele VE, Kelloff GJ, Wilkinson BP, Arnold JT. Cancer Res. 50:2068-2074
(1990).
Zi X, Mukhtar H, Agarwal R. Biochem Biophys Res Commun. 239:334-9 (1997). |
10 g
50 g |
$21.70
$67.40 |
| S3449 |
Simvastatin (For sodium salt - please inquire) |
|
|
| RT |
Synvinolin
A potent HMG-CoA reductase inhibitor and hypocholesterolemic agent.
Inhibits cell proliferation of human glioma cells and of acute myeloid
leukemia cells. Anti-carcinogenic during the promotion phase of
radiation-induced mammary tumors.
Inano H, Suzuki K, Onoda M. Wakabayashi K Carcinogenesis. 18:1723-7
(1997).
Kikuchi T, Nagata Y, Abe T. J Neurooncol. 34:233-9 (1997).
Lishner M, Bar-Sef A, Elis A, Fabian I. J Investig Med. 49:319-24
(2001).
Mol, MJ et al. Lancet. 2:936 (1986). |
50 mg
100 mg
500 mg |
$104.00
$156.70
$655.50 |
| S3452 |
Sinalbin |
|
|
|
C30H42N2O15S2 Mol. Wt.: 34.79
[20196-67-2]
A glucoside found in the seeds of white mustard. Has anti-androgen and
anti-inflammation acitities. Has been shown to inhibit mice prostatic
hyperplasia.
Wu GX, Lin YX, Ou MR, Tan DF Zhongguo Zhong Yao Za Zhi
28:643-6 (2003). |
5 mg
10 mg |
$50.00
$78.00 |
| S3351 |
Sincalide (CCK-8) |
|
|
|
Sincalide corresponds to the C-terminal octapeptide
of cholecystokinin (CCK) which acts on receptors within the gallbladder wall
causing it to contract. |
|
Please inquire |
| S3353 |
Sinomenine |
|
|
|
Sinomenine is an alkaloid isolated from the Chinese
medicinal plant Sinomenium acutum. It has immunomodulating and
anti-inflammatory activities. Its anti-arthritic property is related to the
antiproliferative effects on synovial fibroblasts and lymphocytes. Other
antirheumatic mechanisms are attributed to its ability to decrease PGE2 and
leukotriene C4 synthesis, and inhibit NO production.
Vieregge B, Resch K, Kaever V. Planta Med. 65:80-82 (1999).
Liu L, Buchner E, Beitze D et al. Int J Immunopharmacol.
18:529-43 (1996).
Candinas D, Mark W, Kaever V et al. Transplantation. 62:1855-1860
(1996).
Liu L, Resch K, Kaever V. Int J Immunopharmacol. 16:685-691 (1994).
Liu L. Riese J, Resch K, Kaever V. Arzneimittelforsching. 44:1223-1226
(1994). |
10 g
25 g
50 g |
$38.50
$130.60
$230.50 |
| S3585 |
SIVmac239-1 |
|
|
|
A pathogenic molecular clone of simian
immunodeficiency virus (SIV).
Luciw PA, Pratt-Lowe E, Shaw KE, Levy JA, Cheng-Mayer C. Proc Natl Acad Sci
U S A. 92: 7490-4 (1995). |
1 mg
2 mg
5 mg |
$51.20
$86.40
$153.60 |
| S3586 |
SIVmac239-2 |
|
|
|
|
1 mg
2 mg
5 mg |
$51.20
$86.40
$153.60 |
| S5200 |
SNA 1 |
|
|
| -20 oC |
SNA 1 is a four chain lectin isolated from the bark
of the common elder. It is a ribosome-inactivating protein with low activity
on mammalian ribosomes.
Broekaert WF et al. Biochem J. 221:163 (1984).
VanDamme EJM et al. Eur J Biochem. 235:128
(1996). |
1 mg |
$107.60 |
| SB5776 |
Snake venom - Bothrops alternatus (urutu) |
|
|
|
Known for myotoxic activity. Bothroalternin isolated
from the venom is a new thrombin inhibitor.
Arruda EZ, Silva NM, Moraes RA, Melo PA. Braz Jmed Biol Res. 35:723-726
(2002).
Castro HC, Dutra DL, Oliveira-Carvalho AL, Zingali RB. Toxicon 36:1903-12
(1998). |
100 mg |
$284.60 |
| SB5778 |
Snake venom - Bothrops neuwiedi diporous |
|
|
|
|
100 mg |
$149.10 |
| SC7056 |
Snake venom - Crotalus durissus terrificus |
|
|
|
A potent neurotoxin. Crotoxin (CT), a phospholipase
A2 (PLA2) derived from the venom is a heterodimeric protein. PLA2 is found to
have anti-proliferative activity.
Hawgood BJ. Toxicon 39:1277-82 (2001).
Donato NJ, Martin CA, Perez M, Newman
RA, Vidal JC, Etcheverry M. Biochem Pharmacol. 51:1535-43 (1996). |
100 mg |
$74.60 |
| S5746 |
Solanesol |
|
|
|
A trisesquiterpene alcohol present in tobacco leaf.
It is a possible precusor of polycyclic aromatic hydrocarbons.
Severson RF, Ellington JJ, Schlotzhauer PF et al. J Chromatogr. 139:269-82
(1977). |
50 mg
100 mg
500 mg |
$80.10
$123.20
$400.40 |
| S5745 |
[Tyr1] Somatostatin |
|
|
|
|
1 mg
2 mg
5 mg |
$57.60
$97.60
$172.80 |
| S5747 |
[Tyr11] Somatostatin |
|
|
|
|
1 mg
2 mg
5 mg |
$57.60
$97.60
$172.80 |
| S5748 |
Somatostatin |
|
|
|
|
5 mg
1 g |
$107.60
$3,870.80 |
| S5749 |
Somatostatin-14 |
|
|
|
Growth hormone-release inhibiting factor. It
affects cell proliferation. Induces apoptosis in MCF-7 human breast cancer
cells.
Patel YC. Front Neuroendocrinol. 20:157-98 (1999).
Hocker M. Wiedenmann B. Ital J Gastroenteril. 31 Suppl 2:S139-42
(1999).
Thangaraju M, Sharma K, Liu D et al. Cancer Res. 59:1649-54 (1999). |
5 mg
10 mg
25 mg |
$76.80
$131.20
$230.40 |
| S5751 |
Somatostatin-25 |
|
|
|
|
0.5 mg
1 mg
2.5 mg |
$102.40
$174.40
$307.20 |
| S5750 |
Somatostatin-28 |
|
|
|
|
1 mg |
$416.70 |
| S5752 |
Somatostatin-28 (1-12) |
|
|
|
|
1 mg
2 mg
5 mg |
$108.80
$185.60
$326.40 |
| S5753 |
Somatostatin-28 (1-14) |
|
|
|
|
1 mg
2 mg
5 mg |
$60.80
$185.60
$326.40 |
| S5754 |
Somatostatin Acetate |
|
|
|
|
|
Please inquire |
| S6000 |
Sparfloxacin |
|
|
|
A fluoroquniolone antibacterial, acts on DNA
gyrase.
Piddock LJ, Zhu M. Antimicrob Agents Chemother. 35:2423-7 (1991). |
500 mg
1 g |
$161.10
$263.50 |
| S6018 |
Spectinomycin hydrochloride |
|
|
|
A broad-spectrum aminocyclitol antibiotic that is
highly effective in the treatment of gonorrhea. It has shown neuromuscular
blocking activity by a predominant action on acetylcholine release.
Singh YN, Marshall IG, Harvey AL. Clin Exp Pharmacol Physiol.
6:159-65 (1979).
Holloway WJ. Med Clin North Am. 66:169-73 (1982). |
5 g
25 g |
$44.40
$141.70 |
| S6019 |
Speract |
|
|
|
A peptide associated with eggs of sea urchin,
Lytechinus pictus. It has been shown ot bind to the plasma membrane receptor
of spermatozoa and stimulate sperm respiration.
Repaske DR, Garbers DL. J Biol Chem. 258: 6025-9 (1983). |
1 mg
2 mg
5 mg |
$51.20
$86.40
$153.60 |
| S6129 |
D-Sphingosine |
|
|
| 0 OC |
It induces apoptosis by inhibiting protein kinase.
It is also reported to cause inhibition of adrenaline stimulated cyclic AMP
accumulation, permeation of cells and making them leaky to ATP, inhibition of
adrenaline-stimulated adenylate cyclase inhibition of cyclic AMP.
Souktani R, Berdeaux A, Ghaleh B et al. Am J Physiol cell Physiol.
2797:C158-65 (2000).
Ju TZ, Chen HL, Gu JX, Qin H. Glycoconj J. 12:767-72 (1995).
Johnson JA, Clark RB. Biochem J. 268:507-11 (1990). |
5 mg
25 mg |
$46.10
$172.20 |
| S6131 |
Sphingosine, N, N-dimethyl |
|
|
| 0 OC |
A general modulator of protein kinases. Inhibites
protein kinase C and stimulates src kinase; induces apoptosis in human
leukemia HL-60 cells.
Igarashi Y et al. J Biol Chem. 265:5385 (1990). |
5 mg |
$92.20 |
| S6130 |
Sphingosine 1-phosphate |
|
|
| 0 OC |
Ligand for a family of specific G-protein that
regulates a wide variety of important cellular functions, including vascular
maturation, angiogenesis, apoptosis, cell growth, survival, cytoskeletal
rearrangement and cell motility by divergent pathways.
Spiegel S, Milstien S. Biochem Soc trans. 31:1216-9 (2003). |
1 mg |
$193.70 |
| S6134 |
Spinorphin, bovine |
|
|
|
An endogenous factor that exhibits inhibitory
effects on enkephalin-degrading enzymes.
Yamamoto Y, Ono H, Ueda A, Shimamura M, Nishimura K, Hazato T. Curr Protein
Pept Sci. 3: 587-99 (2002). |
5 mg
10 mg
25 mg |
$166.40
$283.20
$499.20 |
| S6232 |
Spiramycin |
|
|
|
A macrolide antibiotic. It has been shown to
decrease the replication index of human lymphocytes.
Rencuzogullari E, Ila HB, Topatkas M et al. Teratogenesis Carcinogenesis
Mutagenesis. 22:51-58 (2002). |
1 g
5 g |
$39.20
$134.40 |
| S6234 |
Spiramycin Embonate |
|
|
|
|
1 g
5 g |
$51.60
$154.60 |
| S6233 |
Spiramycin Hexanedioate |
|
|
|
Spiramycin Adipate |
1 g
5 g |
$50.40
$151.20 |
| S6235 |
Spironolactone |
|
|
|
An aldosterone antagonist. It directly interferes
with the biosynthesis of aldosterone in bovine and certain human adrenal
cortical tissue.
Cheng SC, Suzuki K, Sadee W et al. Endocrinology. 99:1097-106 (1976).
Bendtzen K, Hansen PR, Rieneck
K. Clin Exp Immunol. 134:151-8 (2003). |
1 g
5 g |
$37.00
$147.90 |
| S7080 |
SR Poly Caspases Assay Kit |
|
|
|
SR-VAD-FMK |
25 Tests
100 Tests |
$178.10
$435.70 |
| S7081 |
SR Caspases 3 and 7 Assay Kit |
|
|
|
SR-DEVD-FMK |
25 Tests
100 Tests |
$200.50
$480.50 |
| S7082 |
SR Caspase 9 Assay Kit |
|
|
|
SR-LEHD-FMK |
25 Tests
100 Tests |
$200.50
$480.50 |
| S7083 |
SR-101-Phe-CMK FLISPTM Assay Kit |
|
|
|
SFCK |
25 Tests
100 Tests |
$144.50
$413.30 |
| S7084 |
SR-101-Leu-CMK FLISPTM Assay Kit |
|
|
|
SLCK |
25 Tests
100 Tests |
$144.50
$413.30 |
| S7600 |
Staurosporine |
|
|
| 2-8 oC |
C28H26N4O3 Mol.Wt.: 466.5 [62996-74-1]
A protein kinase C inhibitor that induces apoptosis in many cell types.
Experimental results obtained in a cell-free assay suggest that cytoplasmic
proteins directly modulated by staurosporine may be involved in signaling the
induction of DNA fragmentation and apoptosis.
Romanova D, Novotny L, Sedlak J et al. Neoplasma. 45: 204-9. (1998).
Zhang H, Hoang T, Saeed B, Ng SC. Prostate. 29:69-76 (1996).
Bertrand R, Solary E, O'connor P et al. Exp Cel
Res. 211:314-21 (1994). |
1 mg
5 mg |
$307.50
$1,200.00 |
| S7717 |
Sterigmatocystin |
|
|
|
C18H12O6 Mol. Wt.: 324.28
[10048-13-2]
Mycotoxin produced by strains of the common molds. Induces sister chromatid exchanges in bone marrow cells of mice. It causes necrosis of the liver and
kidney and has an inhibitory effect on orotic acid incorporation into
nuclear RNA.
Curry PT et al. Mutat. Res. 137:111 (1984).
Terao K Acta Pathol. Jpn. 23:647-53 (1973).
Nel W, Pretorius HE Biochem. Pharmacol. 19:957-9 (1970). |
1 mg
5 mg
10 mg |
$35.00
$132.00
$238.00 |
| S7769 |
Streptomycin sulfate |
|
|
|
An aminosugar containing antibiotic from
Streptomyces griseus. It was the first antibiotic used for the treatment of
tuberculosis. Its mechanism of action is the inhibition of ribosome protein
synthesis.
Kornder JD. Med Hypotheses. 58:34-46 (2002). |
25 g
50 g
100 g |
$19.80
$33.30
$56.70 |
| S7870 |
Streptozocin |
|
|
|
Streptozotocin;
N-(methyl-nitrosocarbamoyl)-a-D-glucosamine
An antitumor agent, used primarily for the treatment of pancreatic cancers.
DuPriest RW Jr., Huntington MC, Massey WH et al. Cancer. 35:358-367
(1975). |
50 mg
100 mg
500 mg |
$20.20
$31.40
$106.40 |
| S7871 |
Stresscopin, human |
|
|
|
A neuropeptide with high affinity for type 2
corticotropin-releasing factor receptor. It is a potent regulator of
cardiovascular functions.
Nazarloo HP, Buttrick PM, Saadat H, Dunn AJ. Curr Protein Pept Sci. 7:
229-39 (2006). |
0.5 mg
1 mg
2.5 mg |
$147.20
$249.60
$441.60 |
| S7872 |
Stresscopin-Related Peptide, human |
|
|
|
A type 2 corticotropin-releasing factor receptor
agonist.
Gardiner SM, March JE, Kemp PA, Bennett T. J Pharmacol Exp Ther. 321: 221-6
(2007). |
0.5 mg
1 mg
2.5 mg |
$160.00
$272.00
$480.00 |
| S8005 |
Substance P |
|
|
|
A neurotransmitter peptide that is distributed in
sensory nerve fibers, bone, and bone-related tissue. It is involved in pain
signal transmission and modulates the function of inflammatory and immune
responses.
Michalski CW, Autschbach F, and Selvaggi F et. al. Am J
Surg. 193: 476-81 (2007).
Corcoran KE, Patel N, Rameshwar P. J Immunol. 178: 2075-82 (2007).
Monnikes H, van der Voort IR, and Wollenberg B et. al. Digestion 71:111-23
(2005). |
5 mg
10 mg
25 mg |
$57.60
$97.60
$172.80 |
| S8006 |
Substance P (1-4) |
|
|
|
|
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| S8007 |
Substance P (1-7) |
|
|
|
|
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| S8008 |
Substance P (1-9) |
|
|
|
|
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| S8009 |
Substance P (7-11) |
|
|
|
|
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| S8010 |
[Nle11] Substance P |
|
|
|
|
1 mg
2 mg
5 mg |
$32.00
$54.40
$96.00 |
| S8011 |
[Pro9] Substance P |
|
|
|
|
0.5 mg
1 mg
2.5 mg |
$32.00
$54.40
$96.00 |
| S8012 |
[Sar9] Substance P |
|
|
|
|
1 mg
2 mg
5 mg |
$44.80
$76.80
$134.40 |
| S8013 |
[Tyr8] Substance P |
|
|
|
|
1 mg
2 mg
5 mg |
$51.20
$86.40
$153.60 |
| S8014 |
Substance P, Free Acid |
|
|
|
|
5 mg
10 mg
25 mg |
$57.60
$97.60
$172.80 |
| S7908 |
Suc-APA-pNA |
|
|
|
C21H27N5O8 Mol Wt: 477.5 |
100 mg
1g |
$60.80
$376.00 |
| S7909 |
Suc-LEPF-pNA |
|
|
|
C35H44N6O11 Mol Wt: 724.7 |
1 mg
10 mg |
$64.00
$256.00 |
| S7910 |
Suc-RGPF-pNA |
|
|
|
C32H41N9O9 Mol Wt: 695.7 |
1 mg
10 mg |
$64.00
$256.00 |
| S7911 |
Suc-SDPF-pNA |
|
|
|
C31H36N6O12 Mol Wt: 684.6 |
1 mg
10 mg |
$64.00
$256.00 |
| S8244 |
Sulbactam |
|
|
|
A beta-lactamase inhibitor that has similar
characteristics as ampicillin. Often used in combination with other
antibiotics.
Wexler HM, Molitoris E, Finegold SM. Antimicrob Agents Chemother.
35:1219-24 (1991).
Foulds G, Stankewich JP, Marshall DC et al.
Antimicrob Agents Chemother. 2:692-9 (1983). |
500 mg
1 g
5 g |
$66.00
$114.20
$439.10 |
| S8243 |
Sulbactam sodium salt |
|
|
|
|
500 mg
1 g
5 g |
$61.60
$112.00
$436.80 |
| S8245 |
Sulfadiazine |
|
|
|
Anti-microbial agent. Its chlorambucil derivative is
found to be a potent antitumor agent.
Huang Z, Yang G, Lin Z, Huang J. Bioorg Med Chem Lett 11:1099-103 (2001). |
50 g
100 g
500 g |
$16.30
$27.20
$108.50 |
| S8246 |
Sulfadimethoxine |
|
|
|
A sulfonamide antibiotic.
Fish JG, Morgan DW, Horton CR. Vet Med Small Anim Clin. 60:1201-3 (1965). |
10 g
25 g
100 g |
$36.70
$66.00
$183.10 |
| S8144 |
Sulfadoxine |
|
|
|
An antibacterial agent.
Bohni E, Fust B, Rieder J. Chemotherapy. 14:195-226 (1969). |
10 g
25 g
100 g |
$43.20
$92.40
$246.40 |
| S8248 |
Sulfamethoxazole |
|
|
|
An antimicrobial. Used in conjunction with
trimethoprim as the first-line treatment for P. carinii pneumonia.
Kovacs JA, Gill VJ, Meshnick S et al. JAMA. 286: 2450-2460 (2001).
Rodriguez MR, Pizzorno MT, Albonico SM. J Pharm Sci. 66:121-123
(1977). |
10 g
25 g
100 g |
$22.40
$39.20
$112.00 |
| S8247 |
Sulfasalazine |
|
|
|
It is a disease-modifying antirheumatic drug (DMARD)
that inhibits extracelluar release of proinflammatory secretory phospholipase A2. It was found to induce
neutrophil apoptosis and regulate human B cell function.
Pruzanski W, Stefanski
E, Vadas P, Ramamurthy NS. Biochem Pharm. 53:1901-1907 (1997).
Akahoshi T, Namai R, Sekiyama N et al. J Leuk Biol. 62:817-826 (1997).
Hirohata S, Ohshima N, Yanagida T, Aramaki K. Int Immunopharm. 2:631-640
(2002). |
10 g
50 g
100 g |
$40.70
$122.00
$196.60 |
| S8251 |
Sulfluramid |
|
|
|
A delayed-action insecticide.
Reid BL, Bennett GW, Barcay SJ. J Econ Entomol. 83:148-152 (1990). |
500 mg
1 g
5 g |
$42.60
$61.60
$246.40 |
| S8044 |
R,S-Sulforaphane |
|
|
| -20 oC |
1-Isothiocyanato-4-(methylsulfinyl)-butane,
D,L-sulforaphane
Sulforaphane is a Phase II enzyme inducer present in brocolli. It was found
to inhibit chemically induced mammary tumor formation in rats. R,S-sulforaphane is a synthetic compound.
Zhang Y, Talalay P, Cho CG, Posner GH. Proc Natl Acad Sci USA. 89:2399-2403
(1992).
Zhang Y, Kensler TW, Cho CG et al. Proc Natl Acad Sci USA. 91:3147-3150
(1994). |
25 mg
50 mg
100 mg
500 mg |
$97.30
$161.80
$291.20
$981.70 |
| S8045 |
S-Sulforaphane |
|
|
|
(+)1-Isothiocyanato-4S-(methylsulfinyl)-butane, D-sulforaphane |
5 mg
10 mg |
$115.30
$196.60 |
| S8046 |
R-Sulforaphane |
|
|
| +4 oC |
(-)1-Isothiocyanato-4R-(methylsulfinyl)-butane,
L-sulforaphane Chiral natural product from broccoli. Inducer of phase II enzymes.
Zhang Y, Talalay P, Cho C-G, Posner GH. Proc Natl Acad Sci USA. 89:2399-2403
(1992). |
10 mg
25 mg
50 mg |
$140.40
$280.60
$530.80 |
| S8049 |
S-Sulforaphene |
|
|
| -20 oC |
(-)4-Isothiocyanato-4S-(methylsulfinyl)-1-butene,
L-sulforaphene
Chiral natural product from radish. |
10 mg
25 mg
50 mg |
$140.40
$280.60
$530.80 |
| S8145 |
Sulindac |
|
|
| RT |
Non-steroidal anti-inflammatory agent. Has
undergone clinical trials as a chemopreventive.
Kelloff GJ, Boone CW, Crowell JA et al. Cancer Epidemiol, Biomarkers Prev.
3:85-98 (1994). |
5 g
25 g |
$32.30
$109.80 |
| S8147 |
Sulindac sulfide |
|
|
| RT |
An active metabolite of Sulindac. Inhibits
cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism.
Meade EA, Smith WL, DeWitt DL. J Biol Chem. 268:6610-6614 (1993).
Piazza GA, Rahm AL, Krutzsch et al. Cancer Res.
55:3110-3116 (1995). |
25 mg
100 mg
500 mg |
$66.00
$183.10
$585.50 |
| S8146 |
Sulindac sulfone |
|
|
|
A metabolite of Sulindac, found to inhibit rat colon
and mammary carcinogenesis without reducing prostaglandin levels.
Piazza GA, Alberts DS, Hixson LJ et al. Cancer Res. 57:2909-2915
(1997).
Thompson HJ, Jiang C, Lu J et al. Cancer Res. 57:267-271
(1997). |
50 mg
250 mg
500 mg |
$66.00
$190.20
$307.50 |
| S8151 |
Sumatriptan Succinate |
|
|
|
Antimigrane. |
100 mg
250 mg
1 g |
$75.00
$145.00
$450.00 |
| S8169 |
Suramin hexasodium salt |
|
|
| +4 deg C |
An antitumor and antiparasitic compound. Uncouples
G-proteins from receptors. A potent inhibitor of melanoma heparanase and tumor cell metastasis.
Huang RR, Dehaven RN, Cheung AH et al. Mol Pharmacol. 37:304-310 (1990).
Nakajima M, DeChavigny A, Johnson CE et al. J BiolChem. 266:9661-9666
(1991). |
50 mg
250 mg |
$108.20
$365.80 |
| S9753 |
Synephrine |
|
|
| 2-8 oC |
1-[4-Hydroxyphenyl]-2-[methyl-amino]ethanol
A biogenic amine present in herbal products and citrus juices. It has
antidepressant-like effects by stimulating a1-adrenoceptors in mice.
Hurlbut JA, Carr JR, Singleton ER et al. J Aoac Int. 81:1121-1127
(1998).
Cancalon PF. J Aoac Int. 82:95-106 (1999).
Song DK, Suh HW, Jung JS et al. Neurosci Lett. 214:107-110 (1996).
Brown CM, McGrath JC, Midgley JM. Br J Pharmacol. 3:417-429 (1988). |
1 g
5 g
10 g |
$27.60
$100.10
$153.70 |
| S9754 |
Syntide 2 |
|
|
|
A synthetic substrate for Ca2+ calmodulin-dependent
protein kinase II.
Colavizza M, Hervagault JF. Biochimie. 84: 605-10 (2002). |
1 mg
2 mg
5 mg |
$64.00
$108.80
$192.00 |
| S9775 |
Systemin |
|
|
|
A polypeptide induces the expression of proteinase
inhibitor gene in (tomato).
Wasternack C, Stenzel I and Hause B et. al. J Plant Physiol. 163: 297-306
(2006). |
0.5 mg
1 mg
2.5 mg |
$57.60
$97.60
$172.80 |
