17-AAG

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Product No	Price	Quantity	Subtotal
A0025-0.5mg	$30.00
A0025-1mg	$35.00
A0025-5mg	$58.00
	Total

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Description

An anologue of geldanamycin. It is a Hsp90 antagonist that induces apoptosis in human leukemia cells. It has been shown to enhance paclitaxel-mediated cytotoxicity and down-regulate vascular endothelial factor expression.

Specifications

Cas No.	75747-14-7
Product ID	A0025
Product Name	17-AAG
Synonym	17-(Allylamino)-17-desmethoxy-geldanamycin; allylaminogeldanamycin
Formula Wt.	585.69
Melting Point	200^oC-205^oC
Purity	≥97%
Solubility	Soluble in DMSO or methanol.
Stability	Protect from light.
Store Temp	+4^oC
Ship Temp	Ambient
References	Rahmani M, Yu C, Dai Y et al. Cancer Research. 63:8420-7 (2003). Nguyen DM, Lorang D, Chen GA et al. Annals of Thoracic Surgery. 72:371-8 (2001).