Aminopterin |
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Description
An inhibitor of dihydrofolate reductase, shown to induce apoptosis in a mouse HGPRT(-) myeloma cell line.
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| Specifications |
| Cas No. |
54-62-6 |
| Product ID |
A5001 |
| Product Name |
Aminopterin |
| Chemical Name |
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid |
| Synonym |
4-Aminofolic acid |
| Formula Wt. |
440.41 |
| Melting Point |
230oC-235oC (dec) |
| Purity |
≥98%
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| Solubility |
Soluble in DMSO or 2 N NaOH (50mg/mL). |
| Store Temp |
Ambient |
| References |
Chung YH, Youn J, Choi Y et al. Immunol Lett. 77:127-31 (2001).
Kremer P, Hartung G, Bauder-Wust U et al. Anticancer Drugs. 13:615-23 (2002). |
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