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Berberine hydrochloride hydrate

Berberine hydrochloride hydrate
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Product No Price Quantity Subtotal
B1870-5g $29.00
B1870-10g $40.00
Total 
 
Description
An isoqinoline alkaloid found in plants of the genera Berberis and Coptis. It was shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. It also inhibites Activator Protein 1 (AP-1), a transcription factor which palys a critical role in inflammation and carcinogenesis.
Specifications
Cas No.
633-65-8
Product ID
B1870
Product Name
Berberine hydrochloride hydrate
Synonym
Berberine hydrochloride; Berberine chloride dihydrate
Formula Wt.
371.82
Melting Point
200oC
Purity
97%
Solubility
Soluble in boiling water. Slightly soluble in cold water.
Stability
Protect from light.
Store Temp
Ambient
References
Fukuda K., Hibiya Y., Mutoh M., Koshiji M., Akao s., Fujiwara H. J. Ethno. 66:227-33 (1999). Fukuda K., Hibiya Y., Mutah M., Koshiji M., Akao s., Fujiwara H. Planta Med. 65:381-3 (1999).