Bongkrekic acid

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Description

A mitochondrial permeability transition pore blocker. It has been shown to inhibit apoptosis by preventing PARP cleavage and DEVDase activity.

Specifications

Cas No.	11076-19-0
Product ID	B5753
Product Name	Bongkrekic acid
Chemical Name	3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,14,18,20-heptaenedioic acid
Formula Wt.	486.6
Melting Point	50^oC-60^oC
Purity	≥98%
Solubility	Soluble as 2N in NH4OH.
Stability	Protect from light.
Store Temp	-20^oC
References	Yoon HS, Moon SC, Kim ND et al. Biochem Bioph Res Co. 276:151-6 (2000). Zamora M, Granell M, Mampel T et al. FEBS Letters. 563:155-60 (2004).