Camptothecin

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Description

A cytotoxic agent, which inhibits DNA topoisomerase I, induces strand breaks in chromosomal DNA and induces apoptosis.

Specifications

Cas No.	7689-03-4
Product ID	C0150
Product Name	Camptothecin
Chemical Name	(S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione
Formula Wt.	348.35
Melting Point	264^oC-267^oC(dec.)
Purity	≥98%
Solubility	Soluble in DMSO.
Store Temp	-20^oC
Ship Temp	Ambient
References	Hertzberg, R.P., Caranfa, M.J., Hecht, S.M. Biochemistry. 28:4629-4638 (1989). Cotter, T.G., Glynn, J.M., Echeverri, F., Green, D.R. Anticancer Res. 12:773-9 (1992).