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Description
Inhibits NF-Kappa-B activiation by preventing TNF-alpha induced degradation and phosphorylation. Renders HL-60 cells susceptible to TNF-alpha induced apoptosis by enhancing caspase3 and caspase8 activities.
Specifications
Cas No.
477-43-0
Product ID
D1627
Product Name
Dehydrocostus Lactone
Formula Wt.
230.3
Store Temp
-20oC
References
Loizzo, M. Anticancer Research (2007), 27(5A), 3293-3300.
Jeong, Gil-Saeng. European Journal of Pharmacology (2007), 565(1-3), 37-44.