Doramapimod

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Product No	Price	Quantity	Subtotal
D5868-10mg	$63.80
D5868-25mg	$132.00
D5868-100mg	$352.00
	Total

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Description

A pyrazole phenyl urea derivative is a reversible, competitive inhibitor of p38 MAP kinase. It interferes with ATP binding of p38. It also blocks tumor necrosis factor-alpha and IL-1β synthesis.

Specifications

Cas No.	2859873-48-4
Product ID	D5868
Product Name	Doramapimod
Chemical Name	1-(3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl)-3-(4-(2-(morpholin-4-yl)ethoxy)naphthalen-1-yl)urea
Synonym	1-[2-(4-Methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea
Formula Wt.	527.66
References	Pargellis, C., Tong, L., Churchill, L., et al. Nat. Struct. Biol. 9, 268-272 (2002).