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Description
A seleno-organic compound showing glutathione peroxidase-like activity that has anti-inflammatory, anti-oxidant, and anti-malarial effects. It has been shown to inhibit NO-induced apoptosis of differentiated PC12 cells, and protect Ca2+ blockage.
Specifications
Cas No.
60940-34-3
Product ID
E0073
Product Name
Ebselen
Synonym
2-Phenyl-1,2-benzisoselenazolin-3-one
Formula Wt.
274.18
Melting Point
180oC-181oC
Purity
≥98%
Solubility
Soluble in DMSO.
Store Temp
-20oC
References
Moretto MB, Franco J, Posser T et al. Neurochem Res. 29:1801-6 (2004).
Lindenblatt N, Schareck W, Belusa L et al. Thromb Haemostasis. 90:882-92 (2003).
Sarker KP, Biswas KK, Rosales JL et al. J Neurochem. 87:1345-53 (2003).