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Description
A synthetic glucocorticoid with anti-inflammatory and anti carcinogenesis properties. It inhibits tumor promotion in mouse skin when applied with a promoting agent at the early stages of promotion. It was also found to inhibit induction of early growth response-1 (Egr-1) gene in SENECAR mice and phospholipid peroxidation in CD1 mice which were exposed to 12-O-tetradecanoyl phorbol-13- acetate (TPA) treatment.