Ganciclovir

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Description

A nucleoside analog used to disrupt DNA replication. It shows antitumor activity when used in combination with HSV1-tk gene transfection.

Specifications

Cas No.	82410-32-0
Product ID	G0152
Product Name	Ganciclovir
Chemical Name	2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]- methyl]-6H-purin-6-one
Synonym	DHPG; 2'NDG; BIOLF
Formula Wt.	255.23
Melting Point	250^oC (dec)
Purity	≥98%
Solubility	Soluble in water.
Store Temp	Ambient
References	Ogilvie, et al. Can. J. Chem. 60:3005 (1982). Raskin, et al. J. Infect. Dis. 155:323 Aghi, Hochberg, Breakfield. J. Gene Med. 2:148 (2000). Li, P.X., Ngo, D., Brade, A.M., Klamut, H.J. Cancer Gene Ther. 6:179-90 (1999).