Irinotecan

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Product No	Price	Quantity	Subtotal
I6932-5mg	$65.00
I6932-10mg	$80.00
I6932-25mg	$180.00
I6932-100mg	$400.00
	Total

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Description

Irinotecan is inhibitor of the nuclear enzyme topoisomerase I, which is involved in cellular DNA replication and transcription. During replication Topoisomerase I mediates the relaxation of super coiled DNA, and it's inhibition results in breakage of the

Specifications

Cas No.	97682-44-5
Product ID	I6932
Product Name	Irinotecan
Chemical Name	[1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11- diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo- 1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester
Formula Wt.	586.68
Purity	≥98%
Solubility	Insoluble in water. Soluble in DMSO
Store Temp	Ambient
References	Kellner U, Rudolph P, Parwaresch R. Onkologie. 23:424-430 (2000). Kalemkerian GP, Worden FP. Expert Opin Investing Drugs. 9:565-79 (2000). Saltz LB. Curr Oncol Rep. 1:155-160 (1999).