Kenpaullone |
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Description
A potent inhibitor of CDK1/cyclin B, that also inhibits CDK2/cyclin A, CDK2/cycline E,
and CDK5/p25. It acts by competitive inhibition of ATP binding.
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| Specifications |
| Cas No. |
142273-20-9 |
| Product ID |
K1655 |
| Product Name |
Kenpaullone |
| Chemical Name |
9-Bromo-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one |
| Formula Wt. |
327.18 |
| Melting Point |
>330oC |
| Purity |
≥95%
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| Solubility |
Soluble in DMSO. Insoluble in water and ethanol. |
| Store Temp |
+4oC |
| References |
Zaharevitz DW, Gussio R, Leost M et al. Cancer Res. 59:2566-9 (1999).
Cole A, Frame S, Cohen P. Biochem J. 377:249-55 (2004). |
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