Levosimendan

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Product No	Price	Quantity	Subtotal
L1884-100mg	$80.40
L1884-250mg	$146.80
L1884-1g	$463.60
	Total

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Description

A Ca(2+) sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration. It has been shown to reduce circulating proinflammatory cytokine interleukin-6 and soluble apoptosis mediators.

Specifications

Cas No.	141505-33-1
Product ID	L1884
Product Name	Levosimendan
Chemical Name	Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6- oxo-3-pyridazinyl)phenyl)hydrazone
Synonym	Simdax
Formula Wt.	280.28
Melting Point	210^oC-214^oC
Purity	≥98%
Solubility	Soluble in water.
Stability	Store in a cool, dry place. Protect from direct light.
Store Temp	+4^oC
References	Udvary E, Papp JG, Vegh A. Br J Pharmacol. 114:656-61 (1995). Parissis JT, Adamopoulos S, Antoniades C et al. Am J Cardiol. 93:1309-12 (2004). Eriksson O, Pollesello P, Haikala H. J Cardiovasc Pharmacol. 44:316-21 (2004).