Lonidamine

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Description

A mitochondria-targeting antitumor agent. It has been shown to induce apoptosis in certain cells, and potentiate cisplatin and paclitaxel activity.

Specifications

Cas No.	50264-69-2
Product ID	L5658
Product Name	Lonidamine
Chemical Name	1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid
Synonym	Diclondazolic acid; DICA; AF-1890; Doridamina.
Formula Wt.	321.16
Melting Point	207^oC
Purity	≥98%
Solubility	Soluble in methanol or acetic acid.
Store Temp	Ambient
References	Orlandi L, Zaffaroni N, Bearzatto A et al. Int J Cancer. 78:377-84 (1998). De Lena M, Lorusso V, Latorre A et al. Eur J Cancer. 37:364-8 (2001). Miyato Y, Ando K. J Radiat Res (Tokyo). 45:189-94 (2004).