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Description
An angiotensin II subtype I (AT1) receptor antagonist used for the treatment of hypertension. It inhibits platelet activity by suppressing thrombin-induced calcium transients and thromboxane release.
Specifications
Cas No.
124750-99-8
Product ID
L5873
Product Name
Losartan potassium
Chemical Name
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'- biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol monopotassium salt
Synonym
Du Pnot-753; Losaprex; Lortaan; Neo-Lotan; Oscaar
Formula Wt.
461.01
Purity
≥98%
Solubility
Soluble in water and alcohol.
Store Temp
Ambient
Ship Temp
Ambient
References
McIntyre M, Caffe SE, Michalak RA, Reid JL. Pharmacol Ther 74:181-94 (1997).
Schwemmer M, Sommer O, Bassenge E. Cardiovasc Drugs Ther. 15:301-7 (2001).