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Description
A potassium ionophore, found to induce cell death and promote the maturation and release of IL-1beta
in lipopolysaccharide primed monocytes and macrophages. It also enhances rapamycin action.
Specifications
Cas No.
28643-80-3
Product ID
N3225
Product Name
Nigericin Sodium
Chemical Name
Antibiotic K 178 Sodium salt
Synonym
Azalomycin M; Helixin C; Polyetherin A.
Formula Wt.
747
Melting Point
245oC-255oC
Purity
≥98%
Solubility
Soluble in chloroform. Practically insoluble in water.
Store Temp
+4oC
References
Fang A, Wong GK, Demain AL. J Antibiot (Tokyo). 53:158-62 (2000).
Hentze H, Lin XY, Choi MS et al. Cell Death Differ. 10:956-68 (2003).