PD325901

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Product No	Price	Quantity	Subtotal
P1202-5mg	$74.80
P1202-25mg	$275.00
P1202-100mg	$572.00
	Total

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Description

A potent inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to inhibit tumor cell growth, has antiangiogenic and antiproliferative activities.

Specifications

Cas No.	391210-10-9
Product ID	P1202
Product Name	PD325901
Formula Wt.	482.19
Solubility	Soluble in DMSO at 12 mg/mL; soluble in ethanol at 6.3 mg/mL with slight warming; very poorly soluble in water
References	Barret, S.D., Bridges, A.J., Dudley, D.T., et al. Bioorg Med Chem Lett 18: 6501-6504 (2008). Ciuffreda L, Del Bufalo D, Desideri M, et al. Neoplasia, 11:720-731, (2009).