Paclitaxel (Natural-from Taxus yunnanensis Cheng et L.K.Fu)

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Product No	Price	Quantity	Subtotal
P0092-1mg	$27.60
P0092-5mg	$48.30
P0092-25mg	$110.40
P0092-100mg	$248.40
	Total

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Description

A natural diterpenoid originally isolated from the stem bark of Taxus brevifolia. It promotes the assembly of stable microtubules and inhibits the disassembly process of microtubules to tubulin by calcium ions and by low temperature. Taxol was shown to have activity against cancers, such as P388 and L1210 leukemia, B16 melanoma, WM-256 carcinosarcoma, Sarcoma 180, Lewis lung tumor, and several xenografts of human tumors including MX-1 mammary, LX-1 l

Specifications

Cas No.	33069-62-4
Product ID	P0092
Product Name	Paclitaxel (Natural-from Taxus yunnanensis Cheng et L.K.Fu)
Synonym	Taxol; Taxol A; Paxene
Formula Wt.	853.9
Melting Point	213^oC-217^oC
Purity	≥98%
Solubility	Insoluble in water. Soluble in ethanol or DMSO (50mg/ml).
Store Temp	-20^oC
Ship Temp	Ambient
References	Wani, M. C., Taylor, H. L., Wall, M. E., Coggon, P., McPhail, A. T. J. Am. Chem. Soc. 93:2325 (1971). Manfredi, J. J., Horwitz, S. B. Pharmacol. Ther. 25:83 (1984). Parness, J., Horwitz, S. B. J. Cell Biol. 91:479 (1981). Schiff, P. B., Fant, J