Rapamycin

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Description

An antifungal antibiotic that has immunosuppressive activity. It blocks cytokine-mediated signal transduction pathways.

Specifications

Cas No.	53123-88-9
Product ID	R0161
Product Name	Rapamycin
Synonym	Sirolimus; Rapamune; AY-22989
Formula Wt.	914.17
Melting Point	183^oC-185^oC
Purity	≥98%
Solubility	Soluble in ether, chloroform, acetone, methanol, DMF, DMSO, and ethanol (up to 2 mM). Sparingly soluble in hexane and petr ether. Insoluble in water.
Stability	Protect from light. Hygroscopic.
Store Temp	+4^oC
References	Singh K. Sun S. Vezina C. J Antibiot (Tokyo). 32:630-45 (1979). Sehgal SN. Ther Drug Monit. 17:660-5 (1995).