Securinine

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Description

A g-aminobutyric acid (GABA) receptor antagonist. Recently, it was found to induce apoptosis in human leukemia HL-60 cells.

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Specifications

Cas No.	5610-40-2
Product ID	S1609
Product Name	Securinine
Chemical Name	Securinan-11-one
Formula Wt.	217.26
Melting Point	142-143^oC
Purity	≥98%
Solubility	Soluble in ethanol 16 mg/mL, DMSO 50 mg/mL. Insoluble in water.
Store Temp	+4^oC
References	Beutler JA, Karbon EW, Brubaker AN et al. Brain Res. 330:135-40 (1985). Dong NZ, Gu ZL, Chou WH, Kwok CY. Chung Kuo Yao Li Hsueh Pao. 20:267-70 (1999).