Tolvaptan

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Description

A potent human vasopressin V2-receptor antagonist. It increases serum sodium concentration in patients with euvolemic or hypervolemic hyponatremia.

Specifications

Cas No.	150683-30-0
Product ID	T5847
Product Name	Tolvaptan
Chemical Name	N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide
Synonym	OPC-41061
Formula Wt.	448.94
References	Yamamura Y, Nakamura S, Itoh S, et al. J. Pharmacol Exp Ther. 287:860-7 (1998). Schrier RW, Gross P, Gheorghiade M, et. al N Engl J Med 355:2099-112 (2006).