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Description
Is a nicotinic receptor partial agonist. Varenicline is a partial agonist of the α4β2 subtype of the nicotinic acetylcholine receptor. In addition it acts on α3β4 and weakly on α3β2 and α6-containing receptors. A full agonism was displayed on α7-receptors.
Specifications
Cas No.
375815-87-5
Product ID
V0369
Product Name
Varenicline Tartrate
Formula Wt.
361.35
Store Temp
Ambient
References
Mihalak KB, Carroll FI, Luetje CW (2006). "Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors". Mol. Pharmacol. 70 (3): 801–5.