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Wortmannin
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Product No Price Quantity Subtotal
W5769-1mg $72.90
W5769-5mg $287.70
Total 
 
Description
Is an inhibitor of PI3-K and DNa-dependent protein kinase, which is known to mediate DNA double strand break repair. It induces apoptosis and also sensitize cells to ionizing radiation.
Specifications
Cas No.
19545-26-7
Product ID
W5769
Product Name
Wortmannin
Chemical Name
(1S,6bR,9aS,11R,11bR)-11-(Acetyloxy)-1,6b,7,8,9a,10,-11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]ideno[4,5-h]-2-benzopyran-3,6,9- trione
Synonym
Wartmannin
Formula Wt.
428.43
Melting Point
240oC
Purity
≥98%
Solubility
Soluble in methanol and DMSO.
Stability
Unstable in aqueous solutions of pH 3-8. Dessicate.
Store Temp
-20oC
Ship Temp
Ambient
References
Boulton S, Kyle S, Yalcintepe L, Durkacz BW. Carcinogenesis. 17 : 2285 -90 (1996). Ng SSW, Tsao MS, Chow S, Hedley DW. Cancer Res. 60: 5451-5 (2000). Kubota N, Okada S, Inada T, Ohnishi K, Ohnishi T. Cancer Lett. 161:141-7 (2000).