Description
7,10-DiTroc-10-Deacetyl Baccatin III is an intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic.
Product Unit Size | Cost | Quantity | Stock |
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7,10-DiTroc-10-Deacetyl Baccatin III is an intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic.
Cas No. | 95603-44-4 |
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Purity | ≥95% |
Formula | C35H38Cl6O14 |
Formula Wt. | 895.38 |
Chemical Name | 7,10-bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetyl baccatin III |
IUPAC Name | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,15-dihydroxy-10,14,17,17-tetramethyl-11-oxo-9,12-bis(2,2,2-trichloroethoxycarbonyloxy)-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
Synonym | 7,10-Bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III,7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III,7,10-Di(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III,7,10-Di-O-[(2,2,2-trichloroethoxy)carbonyl]baccatin III,Carbonic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4a,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,6-diyl bis(2,2,2-trichloroethyl) Ester,7,10-Troc-10-DAB,0-Troc-10-DAB |
Melting Point | 232-234℃ |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet |
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Lu HF1, Sun X, Xu L, Lou LG, Lin GQ Design, synthesis and biological evaluation of novel fluorinated docetaxel analogues. Eur J Med Chem. 2009 44(2):482-91. PMID: 18524425 DOI: 10.1016/j.ejmech.2008.04.004
Iwao Ojima,Ivan Habus. Mangzhu Zhao, et.al New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of β-lactam synthon method Tetrahedron 48, 6985-7012, 1992. doi.org/10.1016/S0040-4020(01)91210-4
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