Description
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
Product Unit Size | Cost | Quantity | Stock |
---|
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
Cas No. | 59277-89-3 |
---|---|
Purity | ≥98% |
Formula | C8H11N5O3 |
Formula Wt. | 225.20 |
Chemical Name | Acycloguanosine; Vipral; Zovirax |
IUPAC Name | 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one |
Melting Point | 256.5-257°C |
Solubility | Slightly soluble in water (0.7 mg/mL). Soluble in 1 M HCl (50 mg/mL), DMSO (7 mg/mL). |
Appearance | White Crystalline Powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.
Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.
Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.
Alkaline phosphatase substrate used to quantify...
σ2 agonist.
Flavonoid found in fruits, vegetables, and grai...
Recombinant HIV-1 antigen fragment.
PDE and adenosine deaminase inhibitor.
ANP fragment, natriuretic peptide; Na+/K+ ATPas...
HDAC6/10 inhibitor.
Endogenous peptide hormone fragment, involved i...
ALK inhibitor.
Endogenous steroid hormone, estradiol metabolit...
p110α PI3K inhibitor.
Endogenous peptide hormone, involved in water h...
Indole found in cruciferous vegetables; AhR ago...
Steroid; AR antagonist.
Triterpene saponin found in species of Panax; 2...
Wip1 inhibitor.
Cyclic peptide mycotoxin produced by Alternaria...
Selective inhibitor of cytochrome P450 1B1 (CYP...
Tropane alkaloid found in plants in the Solanac...
Aminocoumarin; bacterial DNA gyrase inhibitor.<...