Description
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Product Unit Size | Cost | Quantity | Stock |
---|
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Cas No. | 305-03-3 |
---|---|
Purity | ≥99% |
Formula | C14H19Cl2NO2 |
Formula Wt. | 304.21 |
Chemical Name | 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid |
IUPAC Name | 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid |
Synonym | Amboclorin, Leukeran |
Melting Point | 64-66°C |
Solubility | Soluble in alcohol, chloroform or acetone (500 mg/mL). Insoluble in water. |
Appearance | White to off white powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Begleiter A, Mowat M, Israels LG, et al. Chlorambucil in chronic lymphocytic leukemia: mechanism of action. Leuk Lymphoma. 1996 Oct;23(3-4):187-201. PMID: 9031099.
Kundu GC, Schullek JR, Wilson IB. The alkylating properties of chlorambucil. Pharmacol Biochem Behav. 1994 Nov;49(3):621-4. PMID: 7862715.
NSAID; COX-1/2 inhibitor.
Bactericidal
Impurity of omeprazole
Somewhat selective in inhibiting COX-2 over COX...
Endogenous tachykinin peptide, involved in infl...
AurKA inhibitor.
Pt-based DNA cross-linker.
1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...
Synthetic steroid hormone used in HRT; SERM, PR...
Endogenous tachykinin peptide, involved in infl...
Calcium channel blocker.
O-methylated coumarin; Ca2+ channel blocker.
Statin; HMG-CoA reductase inhibitor.
5-FU prodrug; thymidylate synthase inhibitor.
Antimicrobial peptide found in Apis mellifera.<...
Nitrobenzene; HPPD inhibitor.
MAO and histone demethylase LSD1 inhibitor.
Nonpeptide angiotensin II receptor antagonist
Type A trichothecene mycotoxin produced by Fusa...
COVID-19 research