Description
GTPL-5846 activates GPR84, exhibiting pro-inflammatory activity. This compound increases chemotaxis of polymorphonuclear leukocytes and macrophages and stimulates production of pro-inflammatory cytokines.
Product Unit Size | Cost | Quantity | Stock |
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GTPL-5846 activates GPR84, exhibiting pro-inflammatory activity. This compound increases chemotaxis of polymorphonuclear leukocytes and macrophages and stimulates production of pro-inflammatory cytokines.
Cas No. | 83797-69-7 |
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Purity | ≥98% |
Formula | C12H21N3O2 |
Formula Wt. | 239.32 |
Chemical Name | 6-(octylamino)-1H-pyrimidine-2,4-dione |
IUPAC Name | 6-(Octylamino)-2,4(1H,3H)-pyrimidinedione |
Synonym | 6-n-octylaminouracil, 6-OAU |
Solubility | DMSO: < 7 mg/mL |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Suzuki M, Takaishi S, Nagasaki M, et al. Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor. J Biol Chem. 2013 Apr 12;288(15):10684-91. PMID: 23449982.
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