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JTE907

JTE907

Product ID J766160
Cas No. 282089-49-0
Purity ≥98%
Unit SizeCostQuantityStock
1 mg $95.00 In stock
5 mg $325.00 In stock
25 mg $1,100.00 Please Inquire
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  • Product Info
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  • References
  • Description
  • Product Info
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  • Downloads
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Description

JTE907 is a selective inverse-agonist of cannabinoid receptor 2 (CB2). It shows an antiedema effect in a carageenin-induced mouse paw model. Recently, it was used in a study to measure the effects of CB2 interactors with immune response to vaccines in mice. JTE907 enhanced immune response in a murine model.

Product Info

Cas No.

282089-49-0

Purity

≥98%

Formula

C24H26N2O6

Formula Wt.

438.48

Chemical Name

N-(1,3-benzodioxol-5-ylmethyl)-1,2-dihydro-7-methoxy-2-oxo-8-(pentyloxy)-3-Quinolinecarboxamide

IUPAC Name

N-(1,3-benzodioxol-5-ylmethyl)-7-methoxy-2-oxo-8-pentoxy-1H-quinoline-3-carboxamide

Synonym

JTE-907, JTE 907

Solubility

Soluble in DMSO (100 mM), and ethanol (10 mM).

Appearance

White to off-white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

J766160 MSDS PDF

Info Sheet

J766160 Info Sheet PDF

References

Dotsey E, Ushach I, Pone E et al. Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice. Sci Rep. 2017 Feb 17;7:42584. PMID: 28209996.

Iwamura H, Suzuki H, Ueda Y et al. In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for cannabinoid CB2 receptor. J Pharmacol Exp Ther. 2001 Feb;296(2):420-5. PMID: 11160626.

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