Description
Lomustine is a nitrosourea alkylator that exhibits anticancer chemotherapeutic activity. Lomustine is clinically used to treat various forms of cancer and is one component of the “PCV” regimen.
Product Unit Size | Cost | Quantity | Stock |
---|
Lomustine is a nitrosourea alkylator that exhibits anticancer chemotherapeutic activity. Lomustine is clinically used to treat various forms of cancer and is one component of the “PCV” regimen.
Cas No. | 13010-47-4 |
---|---|
Purity | ≥98% |
Formula | C9H16ClN3O2 |
Formula Wt. | 233.70 |
Chemical Name | N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea |
IUPAC Name | 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea |
Synonym | Belustine, Cecenu' CeeNU, CiNU |
Melting Point | 90°C |
Solubility | Soluble in ethanol (45 mg/mL), chloroform, acetone, DMSO (45 mg/mL). |
Appearance | Yellowish Crystal |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Buccheri G, Ferrigno D, Rosso A. A phase II study of methotrexate, doxorubicin, cyclophosphamide, and lomustine chemotherapy and lonidamine in advanced non-small cell lung cancer. Cancer. 1993 Sep 1;72(5):1564-72. PMID: 8394198.
Kamiya S. Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action. Eisei Shikenjo Hokoku. 1986;(104):1-19. PMID: 3471287.
p38 MAPK inhibitor.
Alkaloid found in Fabaceae family plants; α3β...
Saponin found in Dioscorea; Na+/K+ ATPase and C...
Cell membrane permeability modulator, topoisome...
Semi-synthetic diterpene originally found in Ta...
Indirect activator of STING signaling
Macrolide; threonyl-tRNA synthetase/ligase inhi...
JAK1/2/3 inhibitor.
Triterpene sapogenin found in species of Panax;...
Histamine H2 antagonist, GSK-3β inhibitor.
Mycotoxin produced by Aspergillus; actin polyme...
Nucleoside (thymidine) analog.
RXR agonist.
Used to study embryonic cloning; microtubule po...
Anthracycline, DNA intercalator; topoisomerase ...
CDK7 inhibitor
Nucleoside (adenosine) analog; DNA chain termin...
Estradiol metabolite.
Nucleoside (thymidine) analog; DNA chain termin...
Aromatase inhibitor.