LKT Labs

Biochemicals for Life Science Research

Microcystin-RR

Microcystin-RR

Product ID M3407
Cas No. 111755-37-4
Purity ≥95%
Product Unit SizeCostQuantityStock
100 µg $248.20 Please Inquire
1 mg $1,575.00 Please Inquire
Bulk Quote

Quicklinks

Description

Microcystin RR is a cyclic heptapeptide initially produced by species of cyanobacteria Microcystis. Microcystin RR exhibits cytotoxic, pro-oxidative, and carcinogenic properties. Microcystin RR induces endocrine disruption and alters cholesterol synthesis and lipid oxidation in vivo. Additionally, Microcystin RR induces mitochondrial dysfunction and oxidative stress, altering gonadal structure in development. In other animal models, Microcystin RR alters levels of Bcl-2, Bax, p53, and GRP78, inducing apoptosis and liver damage.

Product Info

Cas No.

111755-37-4
Purity

≥95%
Formula

C49H75N13O12
Formula Wt.

1038.20
IUPAC Name

(5R,8S,11R,12S,15S,18S,19S,22R)-8,15-bis[3-(diaminomethylideneamino)propyl]-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,5,12,19-tetramethyl-2-methylidene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid
Synonym

Cyanoginosin-RR
Solubility

Soluble in ethanol/water mixture 1:1 (0.5 mg/mL).

Shipping and Storage

Store Temp

-20°C
Ship Temp

Blue Ice

Downloads

MSDS

M3407 MSDS PDF
Info Sheet

M3407 Info Sheet PDF

References

Pavagadhi S, Natera S, Roessner U, et al. Insights into Lipidomic Perturbations in Zebrafish Tissues upon Exposure to Microcystin-LR and Microcystin-RR. Environ Sci Technol. 2013 Dec 17;47(24):14376-84. PMID: 24152164.

Zhao S, Xie P, Li G, et al. The proteomic study on cellular responses of the testes of zebrafish (Danio rerio) exposed to microcystin-RR. Proteomics. 2012 Jan;12(2):300-12. PMID: 22140076.

Huang P, Zheng Q, Xu LH. The apoptotic effect of oral administration of microcystin-RR on mice liver. Environ Toxicol. 2011 Oct;26(5):443-52. PMID: 20196164.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R2816

    Recombinant HIV-2 gp36

    Recombinant HIV-1 glycoprotein antigen fragment...

    ≥95%
  • R183731

    Resiquimod

    Toll-like receptor 7/8 agonist

    ≥98%
  • P2810

    Phenylbutazone

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • S801001

    SU-5402

    Inhibitor of VEGFR and FGFR.

    ≥98%
  • C179602

    CEP-28122

    ALK inhibitor.

    ≥98%
  • L5751

    Lomerizine Dihydrochloride

    L-type and T-type Ca2+ and TRP antagonist.

    ≥98%
  • S2792

    SGX-523

    MET inhibitor.

    ≥98%
  • G7346

    GSK-2636771

    p110β PI3K inhibitor.

    ≥98%
  • A5039

    Amitraz

    Insecticide; α-adrenergic agonist, MAO inhibit...

    ≥97%
  • S0033

    Saikosaponin B2

    Saponin found in Bupleurum, Heteromorpha, and S...

    ≥98%
  • M577521

    Monascorubrin

    Bulgarialactone azaphilone

    ≥98%
  • R2788

    RGW-611

    Morpholine derivative.

    ≥98%
  • D5692

    Doxifluridine

    5-Fluorouracil prodrug, pyrimidine nucleoside a...

    ≥98%
  • T7034

    Trimethoprim

    Dihydrofolate reductase inhibitor.

    ≥98%
  • G1855

    Gentiopicroside

    Secoiridoid glycoside found in Gentiana and Cep...

    ≥95%
  • S8253

    Sunitinib Malate

    Indoline; PDGFR, VEGFR, c-KIT, FLT3, mTORC1 inh...

    ≥98%
  • H1657

    Heparin-binding Peptide

    Peptide, binds heparin.

    ≥95%
  • B1603

    Beauvericin

    Cyclic hexadepsipeptide mycotoxin produced by C...

    ≥95%
  • G823720

    Gusacitinib

    SYK/JAK inhibitor

    ≥98%
  • A0963

    Adrenocorticotropic Hormone (1-10), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%