Description
Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats.
Product Unit Size | Cost | Quantity | Stock |
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Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats.
Cas No. | 61413-54-5 |
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Purity | ≥98% |
Formula | C16H21NO3 |
Formula Wt. | 275.35 |
Chemical Name | 4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one |
IUPAC Name | 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone |
Synonym | ZK62711, Rolipramum |
Melting Point | 128-129°C |
Solubility | Soluble in DMSO (warm 25mg/ml), ethanol (25 mg/ml warm). |
Appearance | White to off-white powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Hu S, Cao Q, Xu P, et al. Rolipram stimulates angiogensis and attenuates neuronal apoptosis through the cAMP/cAMP-responsive element binding protein pathway following ischemic stroke in rats. Exp Ther Med. 2016 Mar; 11(3):1005-1010. PMID: 26998028.
Li YF, Huang Y, Amsdell S, et al. Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus. Neuropsychopharmacology. 2009 Oct; 34(11):2404-2419. PMID: 19516250.
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