Description
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Product Unit Size | Cost | Quantity | Stock |
---|
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Cas No. | 1246560-33-7 |
---|---|
Purity | ≥98% |
Formula | C17H22N8O |
Formula Wt. | 354.41 |
IUPAC Name | 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine |
Synonym | SB2343, SB-2343, VS5584 |
Solubility | DMSO 71 mg/mL (200.33 mM) Ethanol 3 mg/mL (8.46 mM) Water Insoluble |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013 Feb;12(2):151-61. PMID: 23270925.
NSAID; COX-1/2 inhibitor.
Mixture of kavalactones found in Piper methysti...
Cysteine protease inhibitor.
Recombinant HIV-1 antigen fragment.
JAK2 inhibitor.
Oxidative phosphorylation inhibitor.
Peptide produced in tomato leaves; potential ca...
Alkaline phosphatase substrate used to quantify...
Heterocyclic light-emitting compound, natural l...
Loop diuretic; NKCC symporter inhibitor, CFTR C...
PKA inhibitor.
ATP competitive CDK inhibitor.
Peptide; NMDA partial agonist.
Anthraquinone pigment found in madder root; O-a...
Inhibitor of Monoacyglycerol lipase (MAGL).
Endogenous sphingolipid involved in cell signal...
Cholesterol ester transfer protein inhibitor.
Diterpene found in brewed, unfiltered coffee; F...
Found in propolis; 5-lipoxygenase inhibitor.
MET, FGFR, PDGFR inhibitor.